24 completed, 5 terminated, 3 withdrawn, 2 recruiting. 37 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 37 | Completed 24, Terminated 5, Withdrawn 3, Recruiting 2, Unknown 2, Suspended 1 |
Follow Spinal Stenosis: new trials by email Literature Review of Spinal Stenosis trials Research Report on Spinal Stenosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Spine Surgery 0.9% Sodium Chloride Injection, Dexamethasone 4 Mg/mL Injectable Solution, Dexmedetomidine injection - Spinal Fusion, Spine Disease | Phase 4 | Completed | Poznan University of Medical Sciences | 90 | 2024-03-01 | 2026-05-11 |
| Efficacy of M640 in Acute Lumbosacral Musculoskeletal Conditions. Metaxalone 640 mg Oral Tablet - Sciatica Acute, Lumbar Spinal Stenosis | Phase 4 | Recruiting | Primus Pharmaceuticals | 50 | 2023-11-15 | 2026-09-14 |
| Dexamethasone as Adjuvant to Ropivacaine in Wound Infiltration for Postoperative Analgesia Following Spinal Surgery Ropivacaine 0.75% Injectable Solution, dexamethasone 8mg - Lumbar Spinal Stenosis, Lumbar Disc Herniation | Phase 4 | Completed | University Hospital Fattouma Bourguiba | 60 | 2023-01-01 | 2023-05-23 |
| Erector Spinae Plane Block as Pain Management After Lumbar Fusion Surgery Ropivacaine Hydrochloride Injection, Sodium chloride - Spondylolisthesis, Lumbar Disc Herniation | Phase 4 | Completed | Ilse van de Wijgert | 76 | 2022-06-01 | 2024-04-17 |
| Wound Infiltration With Tramadol, Dexmedetomidine, or Magnesium Plus Ropivacaine for Pain Relief After Spine Surgery Tramadol with ropivacaine, Dexmedetomidine with ropivacaine, Magnesium with ropivacaine - Analgesia, Pain, Postoperative | Phase 4 | Completed | Aristotle University Of Thessaloniki | 72 | 2022-05-10 | 2026-09-30 |
| Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery Bupivacaine-Epinephrine 0.25%-1:200,000 Injectable Solution plus clonidine, normal saline - Lumbar Spinal Stenosis, Lumbar Disc Herniation | Phase 4 | Recruiting | John O'Toole | 125 | 2022-02-01 | 2026-02-17 |
| Methadone for Spinal Fusion Surgery. Methadone, Morphine - Pain, Postoperative, Back Pain | Phase 4 | Terminated | University of Aarhus | 114 | 2021-02-26 | 2024-11-25 |
| Degenerative Lumbar Stenosis Conservative Treatment Goldic serum, Steroid injections, Manual therapy - Spinal Stenosis Lumbar, Spinal Canal Stenosis | Phase 4 | Unknown | Sutherland Medical Center | 90 | 2020-07-01 | 2021-03-11 |
| Liposomal Bupivacaine in One-level Instrumented Posterior Spinal Fusion Liposomal bupivacaine - Lumbar Spinal Stenosis, Lumbar Disc Herniation | Phase 4 | Suspended | Allina Health System | 60 | 2019-01-26 | 2024-12-11 |
| Particulate vs. Nonparticulate Epidural Steroid Injections for Lumbar Foraminal Stenosis Kenalog Injectable Product, Decadron Phosphate, Injectable, Epidural Steroid Injection - Lumbar Spinal Stenosis | Phase 4 | Withdrawn | Hospital for Special Surgery, New York | 2017-12-01 | 2017-12-06 | |
| Efficacy of Using Solum IV and BMC With GFC in TLIF Solum IV, Bone Marrow Concentrate with general fluid concentrate (GFC) in Transforaminal Lumbar Interbody Fusion - Degenerative Disc Disease, Isthmic-lytic Spondylolisthesis | Phase 4 | Withdrawn | Seton Healthcare Family | 2017-09-30 | 2018-04-18 | |
| BIO4 Clinical Case Study: Cervical Spine 1 or 2-Level ACDF utilizing BIO4 with Bio AVS Cervical Allograft (with graft window)., Aviator Anterior Cervical Plating System - Degenerative Disc Disease, Trauma (Including Fractures) | Phase 4 | Completed | Seton Healthcare Family | 20 | 2017-04-06 | 2022-01-14 |
| Postoperative Analgesia With Buprenorphine for Postoperative Pain Control and Quality of Life After Spinal Surgery Buprenorphine, Tramadol - Spinal Stenosis, Pain, Postoperative | Phase 4 | Completed | Seoul National University Hospital | 69 | 2015-01-01 | 2017-05-03 |
| Prolotherapy Versus Epidural Steroid Injections (ESI) for Lumbar Pain Radiating to the Leg prolotherapy solution of 20% dextrose, Epidural Steroid Injection - Sciatica, Spinal Stenosis of Lumbar Region | Phase 4 | Completed | Hadassah Medical Organization | 110 | 2013-12-01 | 2023-06-29 |
| Interbody vs Instrumented Posterolateral Fusion Following Decompression for Lumbar Spinal Stenosis With Degenerative Spondylolisthesis Interbody Fusion, Posterolateral Fusion - Degenerative Spondylolisthesis, Spinal Stenosis | Phase 4 | Unknown | The London Spine Centre | 178 | 2013-12-01 | 2018-08-20 |
| Does PTH 1-34 (Teriparatide) Enhance Spinal Fusion in Humans? Teriparatide - Spinal Stenosis | Phase 4 | Completed | University Hospital, Linkoeping | 34 | 2012-08-01 | 2019-04-17 |
| Effectiveness Study of the Drug Tranexamic Acid to Reduce Post-surgery Blood Loss in Spinal Surgery Tranexamic Acid, Placebo - Lumbar Spinal Stenosis, Thoracic Spinal Stenosis | Phase 4 | Completed | Massachusetts General Hospital | 29 | 2012-08-01 | 2017-06-08 |
| Effect of Nicardipine on Renal Function in Deliberate Hypotension Nicardipine - Spinal Stenosis | Phase 4 | Completed | Yonsei University | 64 | 2012-05-01 | 2014-10-23 |
| Lumbar Epidural Steroid Injections for Spinal Stenosis Multicenter Randomized, Controlled Trial (LESS Trial) Epidural steroid with local anesthetic injection, Epidural local anesthetic injection, Epidural steroid injection - Spinal Stenosis, Low Back Pain | Phase 4 | Completed | University of Washington | 400 | 2011-04-01 | 2017-12-13 |
| Study on the Treatment of Degenerative Lumbar Spine Stenosis With a Percutaneous Interspinous Implant Spacer, physiotherapy - Lumbar Spinal Stenosis | Phase 4 | Terminated | University of Cologne | 22 | 2011-03-01 | 2016-11-07 |
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Intervertebral Disc Displacement (9) · Spondylolisthesis (8) · Low Back Pain (6) · Pain, Postoperative (4) · Spinal Diseases (4) · Intervertebral Disc Degeneration (3) · Intervertebral disc disease (2) · Radiculopathy (2) · Spondylosis (2) · Agnosia (1) · Back Pain (1) · Congenital Abnormalities (1) · Failed Back Surgery Syndrome (1) · Inflammation (1)
Bone Diseases (37) · Musculoskeletal Diseases (37) · Spinal Diseases (33) · Pathological Conditions, Signs and Symptoms (16) · Neurologic Manifestations (12) · Signs and Symptoms (12) · Pain (11) · Hernia (9) · Pathological Conditions, Anatomical (9) · Spondylolysis (8) · Back Pain (7) · Pathologic Processes (6) · Spondylosis (6) · Nervous System Diseases (5) · Postoperative Complications (5)
Dexamethasone (4) · Dexmedetomidine (3) · Laminectomy (3) · Ropivacaine (3) · Saline Solution (3) · Pregabalin (2) · Sodium Chloride (2) · Tramadol (2) · Acetaminophen (1) · Anesthetics, Local (1) · Betamethasone (1) · Buprenorphine (1) · Clonidine (1) · Diphenhydramine (1) · Diskectomy (1)
Dartmouth-Hitchcock Medical Center (3) · Medtronic Spinal and Biologics (3) · Medtronic Spine LLC (2) · Seoul National University Hospital (2) · Seton Healthcare Family (2) · University of Rochester (2) · Vertos Medical, Inc. (2) · Allina Health System (1) · Aristotle University Of Thessaloniki (1) · Coastal Orthopedics & Sports Medicine (1) · Hadassah Medical Organization (1) · Hospital for Special Surgery, New York (1) · Ilse van de Wijgert (1) · John O'Toole (1) · Massachusetts General Hospital (1)
United States (19) · Germany (4) · Poland (3) · Belgium (2) · Canada (2) · Netherlands (2) · South Korea (2) · Sweden (2) · United Kingdom (2) · Australia (1) · Denmark (1) · France (1) · Greece (1) · Iceland (1) · Israel (1)
James N. Weinstein, DO, MS (3) · Bohdan W Chopko, MD (2) · Eeric Truumees, MD (2) · Christopher Alcala-Marquez, MD (1) · Christopher S Bailey, MD (1) · Chul Ho Chang, MD, PhD (1) · David Caraway, MD (1) · David L Caraway, MD, PhD (1) · Dr. Wm Oxner, M.D. (1) · E. Wuelfert, Pharm. (1) · Georgia Tsaousi (1) · Ho-Joong Kim, MD (1) · Jae Hyup Lee, MD, PhD (1) · James L Blair, DO (1)
PMID 22048651, PMID 15995108, PMID 17119140, PMID 17119141, PMID 17538085, PMID 18287602, PMID 18777603, PMID 19018250, PMID 19075203, PMID 19487505, PMID 19755935, PMID 20453723, PMID 20648206, PMID 21311402, PMID 21358354, PMID 21971123, PMID 22272730, PMID 22791040, PMID 24988555, PMID 25692369, PMID 25705958, PMID 26010037, PMID 26096484, PMID 28396242, PMID 28730328, PMID 30863474, PMID 35899459, PMID 40601485, PMID 42053118, PMID 42246693
U01AR045444 (3)