49 completed, 18 unknown, 15 recruiting, 7 terminated. 44 Not applicable, 8 Phase 2, 8 Phase 4, 6 Phase 3, 2 Early Phase 1.
Follow Spinal Fusion: new trials by email Literature Review of Spinal Fusion trials Research Report on Spinal Fusion
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparing Outcomes in Patients Who Have Spinal Surgery Who Have No-Ice Cold and Compression Therapy Using the NICE1 Device Versus Standard of Care ice-free cryopneumatic therapy device - Spinal Surgery, Spinal Fusion | Phase 4 | Enrolling by invitation | Sarasota Memorial Health Care System | 156 | 2026-03-15 | 2026-10-27 |
| Endothelial Damage in Major Spine Surgery, Measured by Circulating Syndecan-1: an Observational Study.(GlycOrtho) Spinal Fusion | Recruiting | Istituto Ortopedico Rizzoli | 30 | 2026-02-28 | 2026-05-22 | |
| IntraVenous Iron in Kids With Iron Deficiency and Scoliosis Study Ferric carboxymaltose IV, Normal Saline (Placebo) - Scoliosis Correction, Iron Deficiency | Phase 2 / Phase 3 | Recruiting | Columbia University | 120 | 2025-11-21 | 2025-11-26 |
| Trans-Auricular Stimulation for Postoperative Inflammation in Spine Surgery Auricular vagus nerve stimulation, Sham Auricular Vagus nerve Stimulation - Spinal Fusion, Hyperglycemia | Not applicable | Recruiting | Alexander T. Yahanda | 50 | 2025-10-08 | 2026-08-18 |
| Postoperative Pain Control in AIS Using Liposomal Bupivacaine vs. 0.25% Bupivacaine With Epinephrine Bupivacaine liposome injectable suspension, Bupivacaine Hydrochloride and Epinephrine Injection - Post Operative Pain, Spinal Fusion | Not applicable | Recruiting | Boston Children's Hospital | 128 | 2025-08-15 | 2025-10-22 |
| Reassessing the Role of Routine Radiographs After Spinal Fusion Surgery Radiography, Spinal Fusion | Completed | Universitaire Ziekenhuizen KU Leuven | 978 | 2025-05-01 | 2025-10-01 | |
| Durability of Suppl. Rod Constructs-SuppleMentAry Rod Technique for Long-segment Posterior Instrumented Spinal Fusions long-segment posterior TL instrumented fusion - Spinal Fusion | Recruiting | AO Foundation, AO Spine | 1244 | 2025-03-24 | 2026-10-01 | |
| Aprepitant Treatment to Prevent Postoperative Nausea and Vomiting in Children Undergoing Scoliosis Surgery Aprepitant, Placebo - Spinal Fusion, Nausea and Vomiting, Postoperative | Phase 2 | Recruiting | IWK Health Centre | 100 | 2025-03-17 | 2026-04-27 |
| Perioperative Sleep Quality and Postoperative Pain Outcomes eCAP - Surgery, Pain | Enrolling by invitation | Grant Heydinger | 166 | 2025-02-03 | 2026-04-06 | |
| Safety and Efficacy of Subdermal Betadine During Posterior Spinal Fusion 10% Povidone-Iodine Arm, Saline Arm - Spinal Fusion | Phase 4 | Completed | Akron Children's Hospital | 60 | 2025-01-03 | 2026-10-27 |
| Swimming-Based Rehabilitation for Recovery After Thoracolumbar Spinal Fusion Swimming-Based Rehabilitation, Standard Rehabilitation - Spinal Fusion, Postoperative Recovery | Completed | Tra Vinh General Hospital | 124 | 2025-01-01 | 2026-05-19 | |
| Clinical Evaluation and Cost-effectiveness Analysis of 3D Digital Surgery in Traumatology patients treated using 3D technology and Patient-Specific Instrumentation, Patients treated with conventional surgery, without using 3D technology - Radius; Deformity, Hip Osteoarthritis | Not applicable | Recruiting | Corporacion Parc Tauli | 180 | 2024-10-21 | 2024-11-12 |
| Perioperative Smoking Cessation in Elderly Chinese Undergoing Spinal Fusion Enhanced recovery after surgery - Spinal Fusion | Not yet recruiting | The Second Hospital of Shandong University | 2000 | 2024-09-01 | 2024-08-29 | |
| Pedicle Screw Malposition in Spine Arthrodesis Surgeries With O-ARM-guided Navigation O-ARM (Medtronic, Inc, Louisville, CO), Conventional corrective surgery for arthrodesis - Spinal Fusion, Spinal Deformity | Not applicable | Unknown | Federal University of Piaui | 124 | 2024-08-01 | 2024-09-25 |
| Low Dose Dexmedetomidine as a Postoperative Pain Adjunct Dexmedetomidine, Normal Saline - Spinal Fusion, Adolescent Idiopathic Scoliosis | Phase 2 | Enrolling by invitation | Nichole Doyle | 46 | 2024-07-01 | 2026-10-05 |
| Active Video Game-Based Exercise Training and Stability Training After AIS Surgery Active Video Based Exercises, Stabilization and Strengthening Exercises, Waiting List-Spine protection principles training - Adolescent Idiopathic Scoliosis, Spinal Fusion | Not applicable | Enrolling by invitation | Istanbul University - Cerrahpasa | 51 | 2024-04-15 | 2026-05-18 |
| Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Spine Surgery 0.9% Sodium Chloride Injection, Dexamethasone 4 Mg/mL Injectable Solution, Dexmedetomidine injection - Spinal Fusion, Spine Disease | Phase 4 | Completed | Poznan University of Medical Sciences | 90 | 2024-03-01 | 2026-05-11 |
| Kids With Iron Deficiency and Scoliosis Oral ferrous sulfate, Oral placebo tablet - Adolescent Idiopathic Scoliosis, Neuromuscular Scoliosis | Not applicable | Recruiting | Columbia University | 275 | 2024-01-11 | 2026-06-26 |
| Regional Nerve Blocks to Improve Analgesia and Recovery in Older Adults Undergoing Spinal Fusion Thoracolumbar Interfascial Plane (TLIP) Block of bupivacaine, Blood Test, 3D CAM Delirium Severity Scoring - Delirium, Pain, Back | Early Phase 1 | Recruiting | University of Iowa | 50 | 2024-01-01 | 2026-03-27 |
| Pulse-Width Modulation Pulse width modulation - Spinal Fusion, Spinal Stenosis | Not applicable | Recruiting | Dartmouth-Hitchcock Medical Center | 50 | 2023-12-01 | 2026-07-09 |
Showing 20 of 102. Sign in to see all of them.
Spinal Stenosis (13) · Scoliosis (12) · Pain, Postoperative (10) · Spinal Diseases (10) · Spondylolisthesis (8) · Intervertebral Disc Degeneration (7) · Pain (6) · Agnosia (4) · Spinal Injuries (4) · Back Pain (3) · Intervertebral disc disease (3) · Postoperative Complications (3) · Spinal Fractures (3) · Ankylosis (2) · Failed Back Surgery Syndrome (2)
Bone Diseases (39) · Musculoskeletal Diseases (38) · Pathological Conditions, Signs and Symptoms (33) · Signs and Symptoms (26) · Spinal Diseases (26) · Neurologic Manifestations (24) · Pathologic Processes (20) · Pain (16) · Spinal Curvatures (13) · Nervous System Diseases (12) · Postoperative Complications (12) · Spondylolysis (8) · Spondylosis (7) · Wounds and Injuries (7) · Back Injuries (6)
Sodium Chloride (5) · Dexmedetomidine (4) · Spinal Fusion (3) · Bupivacaine (2) · Calcium Dobesilate (2) · Control Groups (2) · Dexamethasone (2) · Epinephrine (2) · Glucose (2) · Ropivacaine (2) · Saline Solution (2) · Tranexamic Acid (2) · Acetaminophen (1) · Analgesia, Patient-Controlled (1) · Aprepitant (1)
Istituto Ortopedico Rizzoli (5) · Advanced Scanners Inc. (2) · Aesculap AG (2) · Boston Children's Hospital (2) · Children's Hospital of Philadelphia (2) · Columbia University (2) · Duke University (2) · Hospital for Special Surgery, New York (2) · NYU Langone Health (2) · Nationwide Children's Hospital (2) · State University of New York - Upstate Medical University (2) · Taipei Veterans General Hospital, Taiwan (2) · University of Colorado, Denver (2) · University of Texas at Austin (2) · AO Foundation, AO Spine (1)
United States (48) · Italy (7) · Spain (5) · France (4) · Germany (4) · Taiwan (4) · Canada (3) · China (3) · Netherlands (3) · Turkey (Türkiye) (3) · Belgium (2) · Russia (2) · South Korea (2) · Vietnam (2) · Brazil (1)
Aaron Bernstein, PhD (2) · Craig Birch, MD (2) · Adreanne Rivera, BS (1) · Aleksandr V Krutko, PhD, MD (1) · Alessandro Vergari (1) · Andreas K Andresen, MD (1) · Andrey Grin, MD, PhD (1) · Antonella Granieri, Professor (1) · Ayse Zengin Alpozgen, Assoc. Prof. (1) · Basma Mohamed, M.D. (1) · Binh V. Huynh (1) · Bruce E. Fredrickson, MD (1) · Carlos Eduardo B Lima, MD, PhD (1) · Carolin Meyer, Dr. (1) · Catherine R Olinger, MD (1)
PMID 36401234, PMID 10895746, PMID 11375828, PMID 11929206, PMID 11983659, PMID 15504180, PMID 17413463, PMID 17906567, PMID 18580208, PMID 23220857, PMID 24770995, PMID 28203735, PMID 28986051, PMID 29098088, PMID 30113350, PMID 30662111, PMID 31315670, PMID 33086348, PMID 33094437, PMID 33935153, PMID 34687905, PMID 35447326, PMID 35667730, PMID 36289500, PMID 37000218, PMID 37012023, PMID 37430281, PMID 40142224, PMID 40325670, PMID 40334989, PMID 40601485, PMID 41583840, PMID 42246693, PMID 9505784, PMID 9706923
2008 (1), K23GM152933 (1)