2 completed, 2 recruiting, 1 active not recruiting, 1 enrolling by invitation. 8 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 8 | Completed 2, Recruiting 2, Active not recruiting 1, Enrolling by invitation 1, Unknown 1, Withdrawn 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow Spinal Fusion: new trials by email Literature Review of Spinal Fusion trials Research Report on Spinal Fusion
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| IntraVenous Iron in Kids With Iron Deficiency and Scoliosis Study Ferric carboxymaltose IV, Normal Saline (Placebo) - Scoliosis Correction, Iron Deficiency | Phase 2 / Phase 3 | Recruiting | Columbia University | 120 | 2025-11-21 | 2025-11-26 |
| Aprepitant Treatment to Prevent Postoperative Nausea and Vomiting in Children Undergoing Scoliosis Surgery Aprepitant, Placebo - Spinal Fusion, Nausea and Vomiting, Postoperative | Phase 2 | Recruiting | IWK Health Centre | 100 | 2025-03-17 | 2026-04-27 |
| Low Dose Dexmedetomidine as a Postoperative Pain Adjunct Dexmedetomidine, Normal Saline - Spinal Fusion, Adolescent Idiopathic Scoliosis | Phase 2 | Enrolling by invitation | Nichole Doyle | 46 | 2024-07-01 | 2026-10-05 |
| Analgesic Effects of Perioperative Propranolol Administration for Spine Surgery Propranolol Hcl 40mg Tab, Placebo oral tablet - Lumbar Disc Disease, Spinal Fusion | Phase 2 | Withdrawn | Duke University | 2020-12-01 | 2021-03-16 | |
| KUR-113 Bone Graft Versus Local Autograft for the Treatment of Single-level Transforaminal Lumbar Interbody Fusion TGplPTH1-34 in fibrin, Autologous Bone Graft - Degenerative Disc Disease, Spinal Fusion | Phase 2 | Unknown | Kuros Biosurgery AG | 50 | 2020-08-27 | 2023-08-09 |
| Abaloparatide vs. Placebo in Post-Menopausal Women and Abaloparatide in Men Receiving Initial Spinal Fusion Surgery Abaloparatide, Placebo - Spinal Fusion | Phase 2 | Active not recruiting | Hospital for Special Surgery, New York | 96 | 2019-08-14 | 2026-09-28 |
| A Comparison of Ketamine Infusion Versus Placebo in Opioid Tolerant and Opioid Naive Patients After Spinal Fusion Ketamine, Saline - Spinal Fusion | Phase 2 | Completed | NYU Langone Health | 129 | 2012-11-01 | 2018-06-14 |
| Use of Activated Recombinant FVII in Spinal Surgery eptacog alfa (activated) - Acquired Bleeding Disorder, Spinal Fusion | Phase 2 | Completed | Novo Nordisk A/S | 50 | 2004-07-01 | 2017-01-13 |
Intervertebral Disc Degeneration (2) · Scoliosis (2) · Agnosia (1) · Intervertebral disc disease (1) · Iron Deficiencies (1) · Pain (1) · Pain, Postoperative (1) · Postoperative Nausea and Vomiting (1)
Bone Diseases (4) · Musculoskeletal Diseases (4) · Pathological Conditions, Signs and Symptoms (4) · Signs and Symptoms (4) · Spinal Diseases (4) · Neurologic Manifestations (3) · Pathologic Processes (2) · Postoperative Complications (2) · Spinal Curvatures (2) · Iron Metabolism Disorders (1) · Metabolic Diseases (1) · Nausea (1) · Nervous System Diseases (1) · Neurobehavioral Manifestations (1) · Nutritional and Metabolic Diseases (1)
Glucose (2) · Saline Solution (2) · Aprepitant (1) · Dexmedetomidine (1) · Factor VII (1) · Fibrin (1) · Ketamine (1) · Propranolol (1) · Sodium Chloride (1) · abaloparatide (1)
Columbia University (1) · Duke University (1) · Hospital for Special Surgery, New York (1) · IWK Health Centre (1) · Kuros Biosurgery AG (1) · NYU Langone Health (1) · Nichole Doyle (1) · Novo Nordisk A/S (1)
United States (7) · Canada (1)
Emily Stein, MD (1) · John Chi, MD (1) · Kirsten Boenigk, MD (1) · Mathew Kiberd, MD (1) · Nichole M Doyle, MD (1) · Stephan Frangakis, MD/PhD (1) · Thomas Buchheit, MD (1) · William Maixner, DDS/PhD (1)