395 completed, 117 unknown, 79 recruiting, 44 terminated. 163 Not applicable, 102 Phase 3, 75 Phase 4, 74 Phase 2, 26 Phase 1.
Follow Ankylosis: new trials by email Literature Review of Ankylosis trials Research Report on Ankylosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Land- and Water-Based Exercise in Axial Spondyloarthritis Land-Based Combined Exercise Program, Aquatic Combined Exercise Program, Home Exercise Program - Axial Spondyloarthritis and Ankylosing Spondylitis | Not applicable | Not yet recruiting | Izmir University of Economics | 50 | 2026-12-01 | 2026-09-22 |
| Phase Ia Study of MST-931 in Healthy Adult Subjects MST-931, MST-931 Placebo - Ankylosing Spondylitis (AS) | Phase 1 | Recruiting | Mabsoft Therapeutics (Shanghai) Co., Ltd. | 32 | 2026-11-30 | 2026-11-03 |
| Pain Phenotyping of Rheumatic Diseases - An Observational Study Bedside quantitative sensory testing - Rheumatic Diseases, Lupus Erythematosus, Systemic | Recruiting | National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | 225 | 2026-11-09 | 2026-11-12 | |
| A Pragmatic Trial of Interleukin-17 Inhibition Versus Janus Kinase Inhibition After Tumor Necrosis Factor-alpha Inhibitor Failure in Axial Spondyloarthritis Secukinumab (IL-17i ), Upadacitinib (JAKi) - Axial Spondyloarthritis (AxSpA) | Phase 4 | Not yet recruiting | The University of Texas Health Science Center, Houston | 40 | 2026-11-01 | 2026-10-14 |
| Posture Exercises in Ankylosing Spondylitis Standard Breathing Exercise Program, Posture-Focused Exercise Program - Ankylosing Spondylitis (AS) | Not applicable | Not yet recruiting | Mustafa Akça | 54 | 2026-11-01 | 2026-10-16 |
| A Study of GKL-006Allo Injection in Patients With Ankylosing Spondylitis GKL-006Allo - Ankylosing Spondylitis | Phase 1 | Not yet recruiting | Beijing Gene Key Life Technology Co., Ltd | 12 | 2026-11-01 | 2026-11-04 |
| SLAMF1 Gene Expression in Ankylosing Spondylitis Ankylosing Spondylitis | Not yet recruiting | Assiut University | 100 | 2026-10-30 | 2026-10-30 | |
| Corrective Spinal Surgery for Severe Spinal Curvature in People With Ankylosing Spondylitis pedicle subtraction osteotomy - Ankylosing Spondylitis | Not applicable | Not yet recruiting | China-Japan Friendship Hospital | 35 | 2026-10-30 | 2026-11-12 |
| Ivarmacitinib With or Without Celecoxib for Ankylosing Spondylitis Ivarmacitinib with celecoxib, Ivarmacitinib Monotherapy - Ankylosing Spondylitis (AS) | Phase 4 | Not yet recruiting | Peking University Third Hospital | 138 | 2026-10-25 | 2026-10-27 |
| RENEW Intervention for Axial Spondyloarthritis RENEW - Axial Spondyloarthritis | Not applicable | Recruiting | University of Michigan | 40 | 2026-10-22 | 2026-10-29 |
| Ocular Surface Changes and Meibomian Gland Dysfunction in Rheumatologic Patients Meibomian Gland Dysfunction, Dry Eye Syndromes | Not yet recruiting | Assiut University | 150 | 2026-10-01 | 2026-09-09 | |
| Evaluation of Serum IL-41 Level in Patients With Ankylosing Spondylitis and Psoriatic Arthritis IL 41 - Ankylosing Spondylitis, Psoriasis | Not yet recruiting | Assiut University | 90 | 2026-10-01 | 2026-07-21 | |
| Postural Biofeedback and Exercise in Axial Spondyloarthritis Standard Exercise Program, Wearable Postural Biofeedback - Axial Spondyloarthritis (AxSpA), Ankylosing Spondylitis (AS) | Not applicable | Not yet recruiting | Istanbul University - Cerrahpasa | 38 | 2026-10-01 | 2026-08-21 |
| A Study to Assess the Safety of Subcutaneous Secukinumab for Treatment in Adult Indian Participants With Axial Spondyloarthritis (axSpA), Ankylosing Spondylitis (AS), and Non-Radiographic Axial Spondyloarthritis (nr-axSpA) Axial Spondyloarthritis, Ankylosing Spondylitis | Not yet recruiting | Novartis Pharmaceuticals | 60 | 2026-09-30 | 2026-07-30 | |
| Controlled Reduction of AO Spine B3 Fractures in Ankylosing Spinal Disorders Using an Inflatable Positioning Device: Technical Note and Retrospective Single-centre Case Series Spine Fracture, Osteoporosis | Not yet recruiting | Diakonie-Klinikum Stuttgart | 23 | 2026-09-20 | 2026-09-29 | |
| Surface Topography and Radiographic Spinal Damage in Radiographic Axial Spondyloarthritis DIERS Formetric 4D surface topography - Axial Spondyloarthritis, Ankylosing Spondylitis | Recruiting | Ankara Etlik City Hospital | 53 | 2026-09-19 | 2026-11-12 | |
| Vilamakitug in Spondyloarthritis Placebo-controlled Investigation for Efficacy vilamakitug, placebo - Axial Spondyloarthritis, Ankylosing Spondylitis | Phase 2 | Not yet recruiting | XBiotech, Inc. | 150 | 2026-09-01 | 2026-05-14 |
| 15-Hydroxyprostaglandin Dehydrogenase in Osteoarthritis and Ankylosing Spondylitis Osteoarthritis, Ankylosing Spondylitis | Not yet recruiting | Assiut University | 51 | 2026-08-02 | 2026-08-07 | |
| Safety and Efficacy of Allogeneic Bone Marrow MSCs in Ankylosing Spondylitis IV administration of CG-BM1, Placebo, CG-BM1 - Ankylosing Spondylitis | Phase 1 | Not yet recruiting | Eighth Affiliated Hospital, Sun Yat-sen University | 40 | 2026-07-01 | 2026-06-08 |
| Effectiveness of Retrolaminar Block in Lumbar Spine Fusion With Multimodal Analgesia retrolaminar block, Sham block - Acute Pain, Anesthesia | Not applicable | Recruiting | Pontificia Universidad Catolica de Chile | 44 | 2026-06-30 | 2026-07-06 |
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Spondylitis, Ankylosing (524) · Axial Spondyloarthritis (178) · Arthritis, Rheumatoid (165) · Arthritis, Psoriatic (126) · Spondylarthritis (64) · Crohn Disease (45) · Arthritis (40) · Osteoarthritis (38) · Psoriasis (33) · Colitis, Ulcerative (32) · Non-Radiographic Axial Spondyloarthritis (32) · Spondylarthropathies (30) · Lupus Erythematosus, Systemic (29) · Joint Diseases (21)
Musculoskeletal Diseases (729) · Joint Diseases (714) · Bone Diseases (678) · Spinal Diseases (658) · Arthritis (637) · Spondylitis (635) · Spondylarthropathies (624) · Spondylarthritis (590) · Axial Spondyloarthritis (476) · Skin and Connective Tissue Diseases (209) · Connective Tissue Diseases (179) · Immune System Diseases (178) · Rheumatic Diseases (178) · Autoimmune Diseases (162)
Etanercept (50) · Adalimumab (41) · Infliximab (36) · secukinumab (29) · golimumab (21) · Exercise (12) · Celecoxib (11) · Methotrexate (10) · Certolizumab Pegol (9) · upadacitinib (9) · Sulfasalazine (8) · Surveys and Questionnaires (8) · bimekizumab (8) · ixekizumab (8) · tofacitinib (8)
Novartis Pharmaceuticals (24) · Pfizer (21) · AbbVie (18) · Charite University, Berlin, Germany (14) · Merck Sharp & Dohme LLC (14) · Wyeth is now a wholly owned subsidiary of Pfizer (14) · Assistance Publique - Hôpitaux de Paris (12) · MicroPort Orthopedics Inc. (12) · AbbVie (prior sponsor, Abbott) (11) · UCB Biopharma SRL (9) · National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) (8) · Sun Yat-sen University (8) · Abbott (7) · Assiut University (7) · Biocad (6)
United States (128) · France (115) · Turkey (Türkiye) (99) · Germany (89) · China (88) · United Kingdom (63) · Spain (56) · Netherlands (50) · Canada (48) · Czechia (46) · Belgium (45) · Poland (44) · South Korea (39) · Russia (36) · Italy (29)
Joachim Sieper, MD (6) · Chunde Bao (3) · Finbar O'Shea (3) · Jieruo Gu, Prof (3) · Joachim Sieper, Prof. (3)
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