16 completed. 16 Phase 2, 2 Phase 1, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 16 | Completed 16 |
| Phase 1 | 2 | Completed 2 |
| Phase 3 | 2 | Completed 2 |
Follow Spasm: new trials by email Literature Review of Spasm trials Research Report on Spasm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Use of Corticosteroids in Third Molar Surgery Dexamethasone 4 Mg/mL Injectable Solution, MethylPREDNISolone 40 Mg/mL Injectable Suspension - Inflammation, Pain, Postoperative | Phase 2 / Phase 3 | Completed | Universidad de Granada | 84 | 2022-01-15 | 2023-12-06 |
| Tolperisone in Acute Muscle Spasm of the Back Tolperisone, Placebo - Back Pain, Acute Pain | Phase 2 | Completed | Neurana Pharmaceuticals, Inc. | 415 | 2019-02-01 | 2022-02-01 |
| Vaginal Diazepam for the Treatment of Female Pelvic Pain Diazepam, Placebo - Pelvic Floor Disorders, Pelvic Pain | Phase 2 | Completed | Raymond Foster | 50 | 2013-09-01 | 2024-09-03 |
| Efficacy of a Multi-strain Probiotic in the Treatment of Irritable Bowel Syndrome Kyodophilus multi-strain probiotic capsules, Kyodophilus Matching Placebo Capsules - Irritable Bowel Syndrome, Digestive System Diseases | Phase 1 / Phase 2 | Completed | The Canadian College of Naturopathic Medicine | 100 | 2013-06-01 | 2015-03-17 |
| Trismus Trial of Therabite vs Wooden Spatula in Head and Neck Cancer Patients Wooden spatula, Therabite - Oropharyngeal Cancer, Oral Cancer | Phase 2 | Completed | Brynn Chappell | 71 | 2012-12-01 | 2015-10-01 |
| Omega-3 Fatty Acids for Hyperactivity Treatment in Autism Spectrum Disorder Omega-3 Fatty Acids, Placebo - Autism Spectrum Disorders, Hyperactivity | Phase 2 | Completed | Hugo W. Moser Research Institute at Kennedy Krieger, Inc. | 57 | 2012-09-01 | 2020-08-31 |
| Classroom-based Distance Intervention for Teachers of Children With Attention Deficit Hyperactivity Disorder Teacher Help for ADHD - Attention Deficit Hyperactivity Disorder (ADHD) | Phase 2 | Completed | Dalhousie University | 116 | 2012-02-01 | 2014-03-28 |
| Safety and Efficacy Study of Antioxidants for the Treatment of the Fragile X Syndrome Ascorbic Acid (Vitamin C) and Alpha-tocopherol (Vitamin E), Placebo - Fragile X Syndrome | Phase 2 | Completed | Yolanda de Diego Otero | 30 | 2010-12-01 | 2015-04-14 |
| Topical Radial Artery Vasodilation Nitroglycerin and lidocaine, Placebo - Cardiac Catheterization, Spasm | Phase 2 / Phase 3 | Completed | University of California, San Francisco | 86 | 2010-07-01 | 2018-09-25 |
| Efficacy of a Multi-strain Probiotic in the Treatment of Irritable Bowel Syndrome (IBS) Kyodophilus multi-strain probiotic capsules, Kyodophilus Matching Placebo Capsules - Irritable Bowel Syndrome, Digestive System Diseases | Phase 1 / Phase 2 | Completed | The Canadian College of Naturopathic Medicine | 128 | 2010-05-01 | 2011-04-01 |
| Study of the Safety and Efficacy of OPC-34712 as a Complementary Therapy in the Treatment of Adult Attention Deficit/Hyperactivity Disorder OPDC-34712, Placebo, Stimulant Therapy - Attention Deficit Hyperactivity Disorder | Phase 2 | Completed | Otsuka Pharmaceutical Development & Commercialization, Inc. | 740 | 2010-03-16 | 2023-02-02 |
| Physiotherapy Treatment for Patients Suffering From Head and Neck Cancer physiotherapy - Oral Cavity Carcinoma, Oropharyngeal Cancer | Phase 2 | Completed | Copenhagen University Hospital, Rigshospitalet | 97 | 2008-12-01 | 2013-07-02 |
| The Efficacy and Safety of Phosphatidylserine-Omega3 in Children With Attention-Deficit/ Hyperactivity Disorder Phosphatidylserine-Omega3, Colored cellulose tainted with fishy odor - Attention Deficit/Hyperactivity Disorder (ADHD) | Phase 2 | Completed | Enzymotec | 200 | 2007-03-01 | 2014-03-12 |
| Effects of L-Theanine in Boys With ADHD L-theanine - Attention Deficit Hyperactivity Disorder | Phase 2 | Completed | University of British Columbia | 100 | 2005-10-01 | 2008-05-06 |
| Supplementation of Phosphatidylserine (PS) and n-3 Long Chain Fatty Acids (EPA, DHA) in Children With ADHD Phosphatidylserine-Omega3 - Attention-Deficit/Hyperactivity Disorder | Phase 2 | Completed | Tel-Aviv Sourasky Medical Center | 90 | 2004-07-01 | 2006-11-07 |
| Mexiletine for the Treatment of Focal Dystonia Mexiletine - Blepharospasm, Dystonia | Phase 2 | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 24 | 1998-07-01 | 2008-03-04 |
Attention Deficit Disorder with Hyperactivity (5) · Impulsive Behavior (3) · Trismus (3) · Anxiety Disorders (2) · Colonic Diseases, Functional (2) · Constipation (2) · Diarrhea (2) · Digestive System Diseases (2) · Irritable Bowel Syndrome (2) · Mouth Neoplasms (2) · Mucopolysaccharidosis IV (2) · Oropharyngeal Neoplasms (2) · Acute Pain (1) · Autism Spectrum Disorder (1)
Nervous System Diseases (16) · Neurologic Manifestations (16) · Neuromuscular Manifestations (16) · Pathological Conditions, Signs and Symptoms (16) · Signs and Symptoms (16) · Mental Disorders (7) · Neurodevelopmental Disorders (7) · Attention Deficit and Disruptive Behavior Disorders (5) · Behavior (4) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Genetic Diseases, Inborn (3) · Pain (3) · Carbohydrate Metabolism, Inborn Errors (2) · Child Development Disorders, Pervasive (2)
Ascorbic Acid (1) · Dexamethasone (1) · Diazepam (1) · Docosahexaenoic Acids (1) · Fatty Acids, Omega-3 (1) · Lidocaine (1) · Methylprednisolone (1) · Mexiletine (1) · Nitroglycerin (1) · Physical Therapy Modalities (1) · Tolperisone (1) · Vitamin E (1) · alpha-Tocopherol (1) · brexpiprazole (1) · theanine (1)
The Canadian College of Naturopathic Medicine (2) · Brynn Chappell (1) · Copenhagen University Hospital, Rigshospitalet (1) · Dalhousie University (1) · Enzymotec (1) · Hugo W. Moser Research Institute at Kennedy Krieger, Inc. (1) · National Institute of Neurological Disorders and Stroke (NINDS) (1) · Neurana Pharmaceuticals, Inc. (1) · Otsuka Pharmaceutical Development & Commercialization, Inc. (1) · Raymond Foster (1) · Tel-Aviv Sourasky Medical Center (1) · Universidad de Granada (1) · University of British Columbia (1) · University of California, San Francisco (1) · Yolanda de Diego Otero (1)
United States (6) · Canada (4) · Israel (2) · Spain (2) · Denmark (1) · United Kingdom (1)
Dugald Seely, ND (2) · Abraham Weizman, MD (1) · Andrew Boyle, MBBS, PhD (1) · Dr. Michael Lyon (1) · Lucia M Perez Costillas, MD PhD (1) · Nachum Vaisman, MD (1) · Nezihe Elik, PhD (1) · Paul A Law, M.D. (1) · Penny V Corkum, PhD (1) · Raymond T Foster, MD (1) · Yolanda de Diego Otero, PhD (1)
PMID 18469236, PMID 21807480, PMID 23582415, PMID 24839884, PMID 25187257, PMID 25229260, PMID 29280763, PMID 29526341, PMID 29602860
2009 (1)