586 completed, 159 unknown, 91 recruiting, 53 terminated. 528 Not applicable, 136 Phase 2, 71 Phase 3, 58 Phase 4, 35 Phase 1.
Follow Irritable Bowel Syndrome: new trials by email Literature Review of Irritable Bowel Syndrome trials Research Report on Irritable Bowel Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Well-Being Intervention for People With IBS Well-Being Intervention - Irritable Bowel Syndrome | Not applicable | Not yet recruiting | University of Wisconsin, Madison | 150 | 2026-12-01 | 2026-09-29 |
| Herbal Supplement (Biocidin REMOVE) for Bacterial Overgrowth in Irritable Bowel Syndrome Biocidin REMOVE, Placebo - Irritable Bowel Syndrome (IBS), Small Intestinal Bacterial Overgrowth Syndrome (SIBO) | Phase 2 | Not yet recruiting | Johns Hopkins University | 40 | 2026-11-01 | 2026-10-08 |
| SIMBA in Irritable Bowel Syndrome (IBS) Rifaximin (drug), fluid biopsy capsule - Irritable Bowel Syndrome (IBS), Microbiome | Phase 1 | Not yet recruiting | University of Calgary | 180 | 2026-11-01 | 2026-10-20 |
| Psyllium Husk in Pediatric IBS Psyllium Husk, Conventional therapy group - Prebiotic, IBS (Irritable Bowel Syndrome) | Not applicable | Not yet recruiting | Eman ElHaddad | 70 | 2026-10-10 | 2026-10-19 |
| Association of Diet and IBD IBD, Inflammatory Bowel Disease (Crohn's Disease and Ulcerative Colitis) | Not yet recruiting | Assiut University | 100 | 2026-10-01 | 2026-09-01 | |
| High-Resolution Measurements of Diet-Microbiome Interactions Inulin, Low-fiber control breakfast shake, Atmo Gas-Sensing Capsule - IBS (Irritable Bowel Syndrome) | Not applicable | Not yet recruiting | Stanford University | 40 | 2026-10-01 | 2026-10-05 |
| Personalized Probiotic Treatments for Irritable Bowel Syndrome Probiotic containing B longum, Probiotic Lactobacillus, Placebo - Irritable Bowel Syndrome (IBS) | Not applicable | Enrolling by invitation | McMaster University | 30 | 2026-10-01 | 2026-10-13 |
| Relationship Between Interoception and Postural Control in Constipation-Predominant Irritable Bowel Syndrome Constipation, Irritable Bowel Disease | Recruiting | Saglik Bilimleri Universitesi | 128 | 2026-10-01 | 2026-10-21 | |
| Enzymax DuoBiotics for Irritable Bowel Syndrome Enzymax DuoBiotics, Placebo - Irritable Bowel Syndrome, Irritable Bowel Syndrome (IBS) | Not applicable | Not yet recruiting | Gala Servicios Clinicos S.L. | 120 | 2026-09-30 | 2026-07-23 |
| Feasibility Study of a Guided Imagery Therapy Mobile Application for Functional Abdominal Pain Disorders in Children Guided Imagery Therapy - Functional Abdominal Pain Disorders, Irritable Bowel Syndrome (IBS) | Not applicable | Recruiting | Baylor College of Medicine | 63 | 2026-09-08 | 2026-09-17 |
| Interactive Effects of Early-Life Stress, Diet, and Metabolism on Gastrointestinal Dysfunction With Neuropsychiatric Symptoms Irritable Bowel Syndrome (IBS), Functional Dyspepsia | Not yet recruiting | Shandong University | 200 | 2026-09-01 | 2026-10-01 | |
| Effects of Aerobic Exercise and Pain Neuroscience Education in Irritable Bowel Syndrome Exercise, Pain Neuroscience Education - Irritable Bowel Syndrome | Not applicable | Not yet recruiting | Istinye University | 33 | 2026-09-01 | 2026-02-11 |
| Applications of a Functional Dairy Product in Diet Therapy new functional milk drink, conventional, acidified milk drink - Metabolic Syndrome, IBS - Irritable Bowel Syndrome | Not applicable | Enrolling by invitation | Warsaw University of Life Sciences | 80 | 2026-09-01 | 2026-08-28 |
| Calisthenics Versus Cycling Exercises on Interleukin-6 and Quality of Life in Benha University Students With Irritable Bowel Syndrome Calisthenics exercises, Cycling Exercises, diet advices - Irritable Bowel Syndrome | Not applicable | Not yet recruiting | Cairo University | 60 | 2026-08-20 | 2026-08-12 |
| Study Evaluating the Effect of UCB8600 on Mast Cell Activation in the Human Gut Sample collection - IBS (Irritable Bowel Syndrome) | Not applicable | Recruiting | Guy Boeckxstaens | 60 | 2026-08-18 | 2026-09-10 |
| Psilocybin-Assisted Psychotherapy in Treating Irritable Bowel Syndrome (IBS) Psilocybin 25 mg, Psychotherapy Treatment Session, Niacin 100 mg - IBS - Irritable Bowel Syndrome | Early Phase 1 | Not yet recruiting | NYU Langone Health | 10 | 2026-08-01 | 2026-03-05 |
| The Mechanism Underlying the Analgesic Effect of the Music of IBS Pain Music intervention - Abdominal Pain/ Discomfort, Irritable Bowel Syndrome | Not applicable | Not yet recruiting | Yale University | 30 | 2026-08-01 | 2026-07-02 |
| A Taiwan-Adapted Self-Management Program for Adults With Irritable Bowel Syndrome Comprehensive Self-Management Program, Usual Care - Irritable Bowel Syndrome | Not applicable | Not yet recruiting | National Defense Medical Center, Taiwan | 54 | 2026-07-15 | 2026-07-15 |
| IBS-Oriented CDED Versus Low FODMAP Diet for Irritable Bowel Syndrome Modified Crohn's Disease Exclusion Diet (CDED), Low FODMAP Diet - Irritable Bowel Syndrome (IBS) | Not applicable | Not yet recruiting | Ariel University | 150 | 2026-07-07 | 2026-07-16 |
| Trans Auricular Vagal Nerve Stimulation in Patients With IBS-C Transcutaneous Auricular Vagus Nerve Stimulation (ta-VNS), Sham Transcutaneous Auricular Vagus Nerve Stimulation - Irritable Bowel Syndrome (IBS-C) | Not applicable | Not yet recruiting | West Virginia University | 80 | 2026-07-01 | 2026-06-23 |
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Abdominal Pain (77) · Diarrhea (66) · Gastrointestinal Diseases (60) · Constipation (49) · Inflammatory Bowel Diseases (49) · Colitis, Ulcerative (38) · Fibromyalgia (38) · Crohn Disease (32) · Anxiety Disorders (27) · Depression (27) · Celiac Disease (24) · Fatigue Syndrome, Chronic (18) · Chronic Pain (17) · Digestive System Diseases (17)
Colonic Diseases (981) · Colonic Diseases, Functional (978) · Intestinal Diseases (976) · Digestive System Diseases (974) · Gastrointestinal Diseases (931) · Pathological Conditions, Signs and Symptoms (256) · Signs and Symptoms (214) · Signs and Symptoms, Digestive (163) · Neurologic Manifestations (116) · Pain (97) · Gastroenteritis (78) · Pathologic Processes (66) · Nervous System Diseases (65) · Nutritional and Metabolic Diseases (57) · Mental Disorders (51)
FODMAP Diet (46) · Probiotics (25) · Fecal Microbiota Transplantation (22) · Rifaximin (16) · maltodextrin (14) · Sugars (13) · Psyllium (11) · Cognitive Behavioral Therapy (10) · Diet, Gluten-Free (10) · Diet Therapy (9) · Inulin (9) · Diet (8) · Exercise (8) · linaclotide (8) · Acupuncture Therapy (6)
Mayo Clinic (19) · GlaxoSmithKline (16) · Sahlgrenska University Hospital (16) · Karolinska Institutet (14) · Maastricht University Medical Center (14) · University of Nottingham (14) · University of California, Los Angeles (13) · University Hospital, Rouen (12) · Cairo University (11) · University of Aarhus (10) · University of Michigan (10) · Astellas Pharma Inc (9) · Baylor College of Medicine (9) · Shandong University (9) · Universitaire Ziekenhuizen KU Leuven (8)
United States (292) · Italy (63) · United Kingdom (59) · Sweden (58) · China (56) · Canada (49) · France (43) · Netherlands (35) · Germany (32) · Belgium (28) · Egypt (25) · Poland (25) · Denmark (24) · Spain (22) · Turkey (Türkiye) (20)
Michael Camilleri, MD (7) · Premysl Bercik, MD (5) · Antonio Carroccio, MD (4) · James N Baraniuk, MD (4) · Jan Tack, Professor (4) · Madhusudan Grover, MBBS (4) · Giovanni Barbara, MD (3) · Jacek Piatek, Prof. Dr. (3) · Janne Fassov, PhD (3) · Kirsten Tillisch, MD (3)
PMID 24275240, PMID 9146781, PMID 27144617, PMID 28705783, PMID 34353864, PMID 22825366, PMID 23357491, PMID 25430806, PMID 27147121, PMID 28167156, PMID 12454866, PMID 16678561, PMID 18054549, PMID 23000955, PMID 23357497, PMID 24169272, PMID 24533607, PMID 25083606, PMID 26789872, PMID 26976734, PMID 27144627, PMID 27725146, PMID 28252569, PMID 28487349, PMID 30277655, PMID 30838348, PMID 31499231, PMID 31852769, PMID 32620184, PMID 33009065, PMID 33029843, PMID 33274349, PMID 33493503, PMID 35483736, PMID 35709830, PMID 35889051, PMID 39227769, PMID 40491242, PMID 42320473, PMID 10528943, PMID 10792117, PMID 10839541, PMID 10982758, PMID 11190378, PMID 11239312, PMID 11427329, PMID 11491192, PMID 11559646, PMID 11725167, PMID 11804862
2025 (4), UL1RR024150 (4), 2015 (2), R01DK079866 (2), R01NR004142 (2), R01NR005337 (2), U19AT003266 (2), 2008 (1), 2009 (1), 2014 (1), 2016 (1), 2017 (1), 2019 (1), 2023 (1), 5UH3NS115108-04 (1)