4 completed, 2 terminated, 1 unknown. 3 Phase 2, 2 Phase 1, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Terminated 2, Completed 1 |
| Phase 1 | 2 | Completed 2 |
| Phase 3 | 2 | Completed 1, Unknown 1 |
Follow Tolperisone: new trials by email Literature Review of Tolperisone trials Research Report on Tolperisone
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Tolperisone in Subjects With Pain Due to Acute Back Muscle Spasm Tolperisone Hydrochloride, Placebo - Back Muscle Spasm, Back Pain | Phase 3 | Completed | Neurana Pharmaceuticals, Inc. | 1004 | 2020-12-15 | 2022-03-22 |
| A Phase 1 PK Study of Tolperisone in Healthy Subjects Tolperisone - Healthy | Phase 1 | Completed | Neurana Pharmaceuticals, Inc. | 27 | 2020-07-28 | 2022-02-01 |
| Effects of Tolperisone on Measures of Drowsiness and Cognitive Function Tolperisone Hydrochloride, Cyclobenzaprine Hydrochloride 10 MG, Placebo - Healthy | Phase 1 | Completed | Neurana Pharmaceuticals, Inc. | 39 | 2020-06-20 | 2022-02-01 |
| The Prognostic Value of Biomarkers and the Effect of Tolperisone in Acute Low Back Pain and Sciatic Pain "BETA" Tolperisone Hydrochloride, Placebo - Low Back Pain | Phase 3 | Unknown | Semmelweis University | 150 | 2019-12-13 | 2024-04-17 |
| Tolperisone in Acute Muscle Spasm of the Back Tolperisone, Placebo - Back Pain, Acute Pain | Phase 2 | Completed | Neurana Pharmaceuticals, Inc. | 415 | 2019-02-01 | 2022-02-01 |
| Safety and Preliminary Effectiveness of AV650 in Patients With Spasticity Due to Spinal Cord Injury tolperisone HCl (AV650), Placebo - Muscle Spasticity | Phase 2 | Terminated | Avigen | 120 | 2007-09-01 | 2008-11-04 |
| Safety and Preliminary Effectiveness of AV650 in Patients With Spasticity Associated With Multiple Sclerosis tolperisone HCl - Muscle Spasticity | Phase 2 | Terminated | Avigen | 150 | 2007-09-01 | 2008-11-04 |
Back Pain (3) · Acute Pain (2) · Low Back Pain (2) · Muscle Spasticity (2) · Spasm (2) · Multiple Sclerosis (1) · Muscle Cramp (1) · Spinal Cord Injuries (1)
Neurana Pharmaceuticals, Inc. (4) · Avigen (2) · Semmelweis University (1)
United States (5) · Canada (1) · Czechia (1) · Germany (1) · Hungary (1) · Russia (1) · Serbia (1) · Ukraine (1)
Daniel Bereczki, MD, POhD,DSc (1) · Glenn Morrison, MSc, PhD (1) · Ralph J Marino, MD (1)