62 completed, 22 unknown, 12 recruiting, 5 active not recruiting. 74 Not applicable, 16 Phase 4, 5 Phase 2, 3 Phase 3, 2 Phase 1.
Follow Trismus: new trials by email Literature Review of Trismus trials Research Report on Trismus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Management of Postoperative Complications After Mandibular Third Molar Extraction Using Submucosal Triamcinolone Injection, Kinesiology Taping, and Standard Care Triamcinolone Acetonide 10mg, Kinesiology Taping, Standard Postoperative Care - Trismus, Edema | Not applicable | Not yet recruiting | Allama Iqbal Medical College | 60 | 2027-01-01 | 2026-07-22 |
| Autologous PRP Versus Triamcinolone Acetate in Patients With Oral Submucous Fibrosis Autologous Platelet-Rich Plasma, Triamcinolone Acetate - Oral Submucous Fibrosis | Not applicable | Not yet recruiting | Allama Iqbal Medical College | 40 | 2026-11-01 | 2026-11-03 |
| Swallowing Rehabilitation Program for Head and Neck Tumor Patients Swallowing Rehabilitation Program - Head and Neck Cancer (H&N) | Not applicable | Recruiting | Delta University for Science and Technology | 80 | 2026-08-31 | 2026-10-07 |
| Maitland Mobilization Versus Therapeutic Ultrasound on Trismus Following Third Molar Surgery Maitland Joint Mobilization, Therapeutic Ultrasound group, Control group - Postoperative Trismus | Not applicable | Active not recruiting | Cairo University | 60 | 2026-05-10 | 2026-07-20 |
| "Effect of Preoperative Submucosal Dexamethasone on Postoperative Discomfort After Mandibular Third Molar Surgery" Dexamethasone, No intervention - Impacted Mandibular Third Molar, Postoperative Pain | Phase 4 | Not yet recruiting | Hayat Abad Medical Complex, Peshawar | 268 | 2026-05-01 | 2026-05-01 |
| Preoperative Versus Postoperative Amoxicillin in Impacted Third Molar Surgery Amoxicillin - Impacted Mandibular Third Molar, Impacted Mandibular Third Molar Extraction | Completed | Recep Tayyip Erdogan University | 52 | 2026-04-10 | 2026-10-05 | |
| Effects of Hyaluronic Acid Complex and Dexamethasone on Pain, Swelling, and Trismus After Mandibular Third Molar Surgery Hyaluronic Acid Complex, Dexamethasone, Absorbable Hemostatic Gelatin Sponge (SPONGOSTAN™ Dental) - Postoperative Morbidity | Not applicable | Completed | Cyprus Health and Social Sciences University | 45 | 2026-03-05 | 2026-10-06 |
| Alternating Triamcinolone and Platelet-Rich Plasma Therapy for Oral Submucous Fibrosis Platelet-Rich Plasma (PRP) Injections, Triamcinolone Acetonide - Oral Submucous Fibrosis | Not applicable | Not yet recruiting | Karachi Medical and Dental College | 40 | 2026-03-01 | 2025-12-11 |
| Effect of Preoperative Long-Acting Corticosteroids on Pain, Swelling, and Trismus After Impacted Lower Third Molar Surgery Dexamethasone 8 mg IM, Normal Saline IM - Impacted Mandibular Third Molar, Postoperative Pain | Not applicable | Active not recruiting | Al Salam University | 60 | 2026-01-04 | 2026-03-05 |
| Aescin-Based Herbal Extract (Reparil) for Postoperative Sequelae After Mandibular Third Molar Surgery Escin, Ibuprofen 400 mg - Postoperative Pain, Facial Swelling | Not applicable | Recruiting | Oman Medical Speciality Board | 100 | 2026-01-01 | 2026-10-30 |
| Effect of Platelet-Rich Fibrin on Postoperative Pain, Trismus, and Edema After Mandibular Third Molar Surgery Platelet-rich fibrin (PRF), Sterile Absorbable Gelatin Sponge - Impacted Mandibular Third Molar, Postoperative Pain | Not applicable | Completed | PAEC General Hospital, Islamabad | 134 | 2025-12-09 | 2026-06-29 |
| Natural Enzyme Mouthwash After Third Molar Surgery ORAL7® Mouthwash, 0.2% Chlorhexidine Gluconate Mouthwash - Impacted Third Molar, Postoperative Pain | Not applicable | Completed | MBD MARKETING SDN. BHD. | 58 | 2025-10-06 | 2026-07-01 |
| Sugammadex-Induced Clenching During Neuromuscular Blockade Reversal Sugammadex 1 mg/kg Group, Sugammadex 2 mg/kg Group, Sugammadex 4 mg/kg Group - Neuromuscular Blockade Reversal Agent, Perioperative Complications | Not applicable | Recruiting | Wonkwang University Hospital | 240 | 2025-07-01 | 2026-07-07 |
| Effectiveness of Serratiopeptidase After Mandibular Third Molar Surgery Serratiopeptidase, Standard Postoperative Care - Trismus | Not applicable | Completed | Sharif Medical Research Center | 110 | 2025-06-06 | 2026-04-21 |
| Evaluation of the Effect of Tea Tree and Chlorhexidine Mouthwashes on Healing After Third Molar Extraction Chlorhexidine Gluconate 0.12% Mouthwash, Tea Tree Oil mouthwash - Postoperative Pain, Postoperative Complications | Not applicable | Recruiting | Harran University | 54 | 2025-04-15 | 2025-09-18 |
| Feasibility of Prospective Surveillance and Early Physical Therapy for Trismus Early physical therapy intervention - Head and Neck Cancer, Trismus | Not applicable | Recruiting | University of Alberta | 30 | 2025-03-01 | 2026-08-12 |
| Single-Session Extraoral PBM After Third Molar Extraction Dual-wavelength GaAlAs laser (650+904 nm) - Impacted Mandibular Third Molar, Edema | Not applicable | Completed | Konya Necmettin Erbakan Üniversitesi | 70 | 2025-02-15 | 2026-06-09 |
| Combination of Mixed Drugs vs Ibuprofen: a Randomized Clinical Trial Third molar extraction - Swelling Lips &Amp; Face, Pain | Not applicable | Completed | Universidad Complutense de Madrid | 12 | 2025-02-01 | 2025-08-21 |
| Comparison of Two Different Suture Knot Techniques on Post-Operative Trismus and Swelling After Impacted Third Molar Surgery locking and non locking suture techniques, non locking suture technique - Trismus, Swelling | Not applicable | Completed | Watim Medical & Dental College | 60 | 2025-01-01 | 2026-09-01 |
| Efficacy of Botox Injection of the Masticatory Muscles in Head &Neck Cancer Patients with Trismus After Radiotherapy Echo-guided Botox injection, echo-guided normal saline injection - Trismus, Head and Neck Cancer | Phase 4 | Recruiting | National Taiwan University Hospital | 120 | 2024-12-01 | 2024-12-16 |
Showing 20 of 107. Sign in to see all of them.
Pain (39) · Edema (32) · Pain, Postoperative (23) · Head and Neck Neoplasms (19) · Mouth Neoplasms (6) · Tooth, Impacted (5) · Agnosia (4) · Postoperative Complications (4) · Inflammation (3) · Oral Submucous Fibrosis (3) · Acute Pain (2) · Deglutition Disorders (2) · Facies (2) · Fibrosis (2)
Nervous System Diseases (107) · Neurologic Manifestations (107) · Neuromuscular Manifestations (107) · Pathological Conditions, Signs and Symptoms (107) · Signs and Symptoms (107) · Spasm (107) · Pathologic Processes (33) · Neoplasms (23) · Neoplasms by Site (23) · Pain (23) · Postoperative Complications (21) · Stomatognathic Diseases (19) · Mouth Diseases (11) · Tooth Diseases (7) · Neurobehavioral Manifestations (4)
Dexamethasone (9) · Saline Solution (4) · Amoxicillin (3) · Control Groups (3) · Low-Level Light Therapy (3) · Physical Therapy Modalities (3) · dexketoprofen trometamol (3) · serratiopeptidase (3) · Arnicae flos extract (2) · Escin (2) · Ibuprofen (2) · Methylprednisolone (2) · Metronidazole (2) · Tablets (2) · Triamcinolone Acetonide (2)
Konya Necmettin Erbakan Üniversitesi (4) · University of Medicine and Pharmacy at Ho Chi Minh City (4) · Cairo University (3) · Federal University of the Valleys of Jequitinhonha and Mucuri (3) · Universidad Complutense de Madrid (3) · Yuzuncu Yil University (3) · Allama Iqbal Medical College (2) · Hacettepe University (2) · National Taipei University of Nursing and Health Sciences (2) · PAEC General Hospital, Islamabad (2) · Taipei Medical University (2) · University of Alberta (2) · University of Sao Paulo (2) · Abant Izzet Baysal University (1) · Afyonkarahisar Health Sciences University (1)
Turkey (Türkiye) (27) · Pakistan (9) · Brazil (8) · Egypt (7) · United States (5) · Vietnam (5) · France (4) · Spain (4) · Taiwan (4) · Cyprus (3) · Belgium (2) · Canada (2) · Malaysia (2) · South Korea (2) · Sweden (2)
Dilek Menziletoglu, Dr (2) · Margaret McNeely, PhD (2) · Abdul Kalam Azad, MDS (1) · Ahmed K Fawzi, BDS, MSc, PhD (1) · Andrea Park, MD (1) · Anna Catharina V Armond (1) · Anna Janas-Naze, DMD,PhD,Prof (1) · Barbara Burgos, PhD (1) · Bijan Movahedian, Oral and maxillofacial surgeon (1) · Bozkurt Ku Isik, Prof Dr (1) · Cheolhyeong Lee, MD (1) · Claire Gourbeix, MD (1)
PMID 25229260, PMID 10071296, PMID 10772298, PMID 12361079, PMID 12625522, PMID 12988177, PMID 14600686, PMID 15172646, PMID 15979480, PMID 16280237, PMID 16915978, PMID 17157479, PMID 18457329, PMID 18985681, PMID 19375022, PMID 20014446, PMID 20623305, PMID 21541945, PMID 21740371, PMID 21794962, PMID 21840283, PMID 21845387, PMID 22090247, PMID 22108231, PMID 22398186, PMID 22422558, PMID 22434715, PMID 22654361, PMID 22864015, PMID 23078983, PMID 23122432, PMID 23358022, PMID 23444095, PMID 23512235, PMID 23720248, PMID 24478217, PMID 24658376, PMID 2469747, PMID 24817237, PMID 24909649, PMID 24986051, PMID 25224592, PMID 25290132, PMID 25529005, PMID 25853044, PMID 26607842, PMID 26910697, PMID 26984249, PMID 2734406, PMID 28397778
2019 (3)