150 completed, 46 unknown, 17 recruiting, 11 terminated. 122 Not applicable, 28 Phase 4, 27 Phase 2, 23 Phase 3, 7 Phase 1.
Follow Spasm: new trials by email Literature Review of Spasm trials Research Report on Spasm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Management of Postoperative Complications After Mandibular Third Molar Extraction Using Submucosal Triamcinolone Injection, Kinesiology Taping, and Standard Care Triamcinolone Acetonide 10mg, Kinesiology Taping, Standard Postoperative Care - Trismus, Edema | Not applicable | Not yet recruiting | Allama Iqbal Medical College | 60 | 2027-01-01 | 2026-07-22 |
| Swallowing Rehabilitation Program for Head and Neck Tumor Patients Swallowing Rehabilitation Program - Head and Neck Cancer (H&N) | Not applicable | Recruiting | Delta University for Science and Technology | 80 | 2026-08-31 | 2026-10-07 |
| Maitland Mobilization Versus Therapeutic Ultrasound on Trismus Following Third Molar Surgery Maitland Joint Mobilization, Therapeutic Ultrasound group, Control group - Postoperative Trismus | Not applicable | Active not recruiting | Cairo University | 60 | 2026-05-10 | 2026-07-20 |
| "Effect of Preoperative Submucosal Dexamethasone on Postoperative Discomfort After Mandibular Third Molar Surgery" Dexamethasone, No intervention - Impacted Mandibular Third Molar, Postoperative Pain | Phase 4 | Not yet recruiting | Hayat Abad Medical Complex, Peshawar | 268 | 2026-05-01 | 2026-05-01 |
| Preoperative Versus Postoperative Amoxicillin in Impacted Third Molar Surgery Amoxicillin - Impacted Mandibular Third Molar, Impacted Mandibular Third Molar Extraction | Completed | Recep Tayyip Erdogan University | 52 | 2026-04-10 | 2026-10-05 | |
| Effects of Hyaluronic Acid Complex and Dexamethasone on Pain, Swelling, and Trismus After Mandibular Third Molar Surgery Hyaluronic Acid Complex, Dexamethasone, Absorbable Hemostatic Gelatin Sponge (SPONGOSTAN™ Dental) - Postoperative Morbidity | Not applicable | Completed | Cyprus Health and Social Sciences University | 45 | 2026-03-05 | 2026-10-06 |
| Alternating Triamcinolone and Platelet-Rich Plasma Therapy for Oral Submucous Fibrosis Platelet-Rich Plasma (PRP) Injections, Triamcinolone Acetonide - Oral Submucous Fibrosis | Not applicable | Not yet recruiting | Karachi Medical and Dental College | 40 | 2026-03-01 | 2025-12-11 |
| Implementation Strategies for Caregiver and Teacher Use of Behavioral Interventions: Aim 2 Positive Behavior Management Toolkit for Caregivers, Positive Behavioral Management Toolkit for Teachers - Attention Deficit Hyperactivity Disorder Symptoms | Not applicable | Enrolling by invitation | Children's Hospital of Philadelphia | 100 | 2026-02-03 | 2026-02-05 |
| Effect of Preoperative Long-Acting Corticosteroids on Pain, Swelling, and Trismus After Impacted Lower Third Molar Surgery Dexamethasone 8 mg IM, Normal Saline IM - Impacted Mandibular Third Molar, Postoperative Pain | Not applicable | Active not recruiting | Al Salam University | 60 | 2026-01-04 | 2026-03-05 |
| Aescin-Based Herbal Extract (Reparil) for Postoperative Sequelae After Mandibular Third Molar Surgery Escin, Ibuprofen 400 mg - Postoperative Pain, Facial Swelling | Not applicable | Recruiting | Oman Medical Speciality Board | 100 | 2026-01-01 | 2026-01-15 |
| Effect of Platelet-Rich Fibrin on Postoperative Pain, Trismus, and Edema After Mandibular Third Molar Surgery Platelet-rich fibrin (PRF), Sterile Absorbable Gelatin Sponge - Impacted Mandibular Third Molar, Postoperative Pain | Not applicable | Completed | PAEC General Hospital, Islamabad | 134 | 2025-12-09 | 2026-06-29 |
| The Relationship of the Joint Blockage and Muscle Spasm Mobilization technique for sacroiliac joint - NO DECOMPENSATED ILLNESS, Muscle Cramps | Not applicable | Completed | Charles University, Czech Republic | 40 | 2025-11-10 | 2025-12-04 |
| Natural Enzyme Mouthwash After Third Molar Surgery ORAL7® Mouthwash, 0.2% Chlorhexidine Gluconate Mouthwash - Impacted Third Molar, Postoperative Pain | Not applicable | Completed | MBD MARKETING SDN. BHD. | 58 | 2025-10-06 | 2026-07-01 |
| Prospective Register Study to Assess Eligibility for and Efficacy of Surgical Treatment in Patients With nEuRovascular Conflict Trigeminal Neuralgia, Tic Douloureux | Not yet recruiting | Gerrit A Schubert | 5001 | 2025-10-01 | 2025-08-21 | |
| Evaluating a Digital Cognitive Training Intervention in Adults With ADHD Digital Cognitive Training, Digital Non-cognitive Training Intervention - ADHD | Not applicable | Not yet recruiting | McMaster University | 52 | 2025-08-01 | 2025-07-22 |
| Caregiver Implementation Strategies Field Pre-Test Implementation Resource Package for Caregivers - Attention Deficit Hyperactivity Disorder Symptoms | Not applicable | Completed | Children's Hospital of Philadelphia | 20 | 2025-07-30 | 2026-01-26 |
| Magnesium and Cramping Magnesium sulfate, Ketamine, Placebo - Uterine Cramps, Postoperative Pain Management | Phase 4 | Recruiting | Corewell Health East | 150 | 2025-07-29 | 2025-08-20 |
| Dry Needling for Temporomandibular Disorder Dry Needling, sham needling - TMD/Orofacial Pain, Muscle Spasm | Not applicable | Completed | Atlas University | 40 | 2025-07-28 | 2026-03-24 |
| Sugammadex-Induced Clenching During Neuromuscular Blockade Reversal Sugammadex 1 mg/kg Group, Sugammadex 2 mg/kg Group, Sugammadex 4 mg/kg Group - Neuromuscular Blockade Reversal Agent, Perioperative Complications | Not applicable | Recruiting | Wonkwang University Hospital | 240 | 2025-07-01 | 2026-07-07 |
| Effectiveness of Serratiopeptidase After Mandibular Third Molar Surgery Serratiopeptidase, Standard Postoperative Care - Trismus | Not applicable | Completed | Sharif Medical Research Center | 110 | 2025-06-06 | 2026-04-21 |
Showing 20 of 241. Sign in to see all of them.
Trismus (106) · Attention Deficit Disorder with Hyperactivity (46) · Pain (43) · Edema (32) · Hemifacial Spasm (23) · Pain, Postoperative (23) · Head and Neck Neoplasms (19) · Impulsive Behavior (19) · Anxiety Disorders (7) · Blepharospasm (7) · Mouth Neoplasms (6) · Acute Pain (5) · Autistic Disorder (5) · Back Pain (5)
Neurologic Manifestations (241) · Neuromuscular Manifestations (241) · Pathological Conditions, Signs and Symptoms (241) · Signs and Symptoms (241) · Nervous System Diseases (239) · Mental Disorders (55) · Neurodevelopmental Disorders (48) · Attention Deficit and Disruptive Behavior Disorders (46) · Stomatognathic Diseases (42) · Pathologic Processes (41) · Pain (35) · Mouth Diseases (33) · Behavior (29) · Neoplasms (25)
Dexamethasone (9) · Botulinum Toxins, Type A (7) · Saline Solution (6) · Methylphenidate (5) · Amoxicillin (3) · Control Groups (3) · Guanfacine (3) · Low-Level Light Therapy (3) · Methylprednisolone (3) · Nitroglycerin (3) · Physical Therapy Modalities (3) · Sugars (3) · cyclobenzaprine (3) · dexketoprofen trometamol (3) · serratiopeptidase (3)
Hacettepe University (4) · Konya Necmettin Erbakan Üniversitesi (4) · Shire (4) · University of Medicine and Pharmacy at Ho Chi Minh City (4) · Cairo University (3) · Children's Hospital of Philadelphia (3) · Federal University of the Valleys of Jequitinhonha and Mucuri (3) · National Institute of Neurological Disorders and Stroke (NINDS) (3) · Universidad Complutense de Madrid (3) · Yuzuncu Yil University (3) · Assistance Publique - Hôpitaux de Paris (2) · Charles University, Czech Republic (2) · Corewell Health East (2) · Flex Pharma, Inc. (2) · Ipsen (2)
United States (57) · Turkey (Türkiye) (33) · France (14) · Canada (10) · Pakistan (10) · Brazil (9) · China (9) · Egypt (9) · Spain (8) · South Korea (6) · Belgium (5) · Germany (5) · Israel (5) · Vietnam (5) · Taiwan (4)
Dilek Menziletoglu, Dr (2) · Dugald Seely, ND (2) · Gwendolyn M Lawson, PhD (2) · Jeong Jin Lee, MD, PhD (2) · Margaret McNeely, PhD (2) · Sharon B. Wigal, Ph.D. (2) · Wei-wei Chang, Ph.D. (2) · Won Ho Kim, MD (2) · Aarthi Narasimhan, MD (1) · Abdul Kalam Azad, MDS (1) · Abraham Weizman, MD (1) · Ahmed K Fawzi, BDS, MSc, PhD (1)
PMID 25229260, PMID 35201607, PMID 37811711, PMID 10071296, PMID 10772298, PMID 12145388, PMID 12361079, PMID 12625522, PMID 12988177, PMID 1448532, PMID 14600686, PMID 15172646, PMID 15979480, PMID 16197668, PMID 16275814, PMID 16280237, PMID 16585288, PMID 16676783, PMID 16915978, PMID 17157479, PMID 17372077, PMID 17558461, PMID 18049292, PMID 18077953, PMID 18457329, PMID 18469236, PMID 18577286, PMID 18728591, PMID 18985681, PMID 19375022, PMID 19506571, PMID 20014446, PMID 20623305, PMID 21241954, PMID 21541945, PMID 21740371, PMID 21794962, PMID 21807480, PMID 21840283, PMID 21845387, PMID 22090247, PMID 22092807, PMID 22108231, PMID 22272653, PMID 22398186, PMID 22422558, PMID 22434715, PMID 22619887, PMID 22654361, PMID 22864015
2019 (3), 2009 (1), 2016 (1), 2023 (1), K23MH122577 (1), P50DA009262 (1), R01HD038461 (1), R01MH083707 (1), R01MH095766 (1), R01NS100810 (1), R34MH132718 (1)