94 completed, 29 unknown, 10 terminated, 5 recruiting. 44 Not applicable, 31 Phase 4, 27 Phase 2, 26 Phase 3, 14 Phase 1.
Follow Nitroglycerin: new trials by email Literature Review of Nitroglycerin trials Research Report on Nitroglycerin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Utilize Imaging to Assess Changes in Hepatocellular Carcinoma Perfusion as Potentiated by Intra-Arterial Nitroglycerin Parenchymal Blood Volume (PBV) Imaging, Nitroglycerin, Medical Record Review - Hepatocellular Carcinoma (HCC), Liver Cancer, Adult | Phase 2 | Not yet recruiting | University of California, San Francisco | 50 | 2026-12-15 | 2026-10-13 |
| EIT Evaluation of Different Antihypertensive Agents on the Ventilation-Perfusion Ratio in Patients With Acute Respiratory Failure Nitroglycerin, Nicardipine - Acute Respiratory Failure (ARF), Hypertension | Not applicable | Not yet recruiting | First Affiliated Hospital of Wannan Medical College | 12 | 2026-07-15 | 2026-07-02 |
| Topical Nitroglycerin Versus Lateral Internal Sphincterotomy for Chronic Anal Fissure Topical 0.2% Glyceryl Trinitrate (Nitroglycerin) Ointment, Lateral Internal Sphincterotomy - Chronic Anal Fissure | Not applicable | Completed | Sheikh Zayed Federal Postgraduate Medical Institute | 72 | 2026-06-15 | 2026-10-21 |
| Comparison of Mean Arterial Pressure After Endotracheal Intubation in Patients Undergoing Spine Surgery With Pre-emptive Nitroglycerine Versus Dexmedetomidine Nitroglycerin (NTG), Dexmedetomidine - Hemodynamics, Arterial Pressure | Not applicable | Completed | Mayo Hospital Lahore | 80 | 2026-01-10 | 2026-10-28 |
| NICardipine for Fast Achievement of Systolic BP Targets in ICH Nicardipine, Glyceryl trinitrate - Intracerebral Haemorrhage | Phase 4 | Recruiting | Aarhus University Hospital | 88 | 2025-10-01 | 2026-06-24 |
| Precise Endoscopic Application of Nitroglycerin in Preventing Post-ERCP Pancreatitis Nitroglycerin (NTG), Normal Saline (0.9% NaCl) - Pancreatitis | Phase 4 | Recruiting | National Cheng-Kung University Hospital | 440 | 2025-09-15 | 2025-12-08 |
| Effect of Nitroglycerin Hydrogel on Repairing Critical Bone Defects Nitroglycerin - Bone Regeneration, Periodontal Bone Loss | Not applicable | Not yet recruiting | Minia University | 33 | 2025-04-01 | 2025-04-13 |
| Efficacy and Safety of GTN vs. Nifedipine in Acute Anal Fissure: A Clinical Trial Glyceryl Trinitrate (GTN) 0.2% Ointment, Glyceryl Trinitrate (GTN) 0.4% Ointment, Nifedipine 0.2% Ointment - Acute Anal Fissure, Anal Pain | Phase 4 | Completed | Hafiz Muhammad Hamza | 110 | 2025-03-17 | 2025-05-14 |
| Evaluating the Effects of Nitroglycerin on Heart Function and Urinary Output in Patients With Acute Heart Failure Nitroglycerin (NTG) - Acute Heart Failure (AHF) | Phase 4 | Completed | Copenhagen University Hospital, Hvidovre | 21 | 2025-02-01 | 2026-03-18 |
| The Effect of Sublingual Nitroglycerin on Absolute Coronary Blood Flow Glycerin trinitrate (GTN), Saline (NaCl 0,9 %) (placebo) - Coronary Arterial Disease (CAD), Angina (Stable) | Phase 4 | Completed | VZW Cardiovascular Research Center Aalst | 40 | 2024-07-01 | 2025-03-28 |
| Comparative Study of Intravenous Labetalol Versus Intravenous Nitroglycerin Versus Sublingual Nifedipine Labetalol, Nitroglycerine, Nifedipine - Severe Preeclampsia | Not applicable | Unknown | Sohag University | 60 | 2024-03-30 | 2024-02-20 |
| Topical Nitro or Placebo Pre-Cath NitroBid, Placebo - Coronary Artery Disease | Phase 2 | Unknown | Thomas Jefferson University | 256 | 2024-03-01 | 2024-03-04 |
| AKI Risk Factors Analysis After Intentional Hypotensive Anesthesia Nitroglycerin - Acute Kidney Injury (Nontraumatic), Hypotension Drug-Induced | Recruiting | Kaohsiung Medical University Chung-Ho Memorial Hospital | 50 | 2024-03-01 | 2024-02-14 | |
| Preoperative Sildenafil Administration for Hepatectomy Sildenafil 100 MG - Central Venous Pressure, Hepatectomy | Not applicable | Unknown | First People's Hospital of Chenzhou | 16 | 2024-02-01 | 2024-06-27 |
| The Effect of Intranasally Administered Nitroglycerin on Hemodynamic Response to Laryngoscopy and Intubation Among Patients Undergoing Coronary Artery Bypass Grafting (CABG) Surgery Nitroglycerin (NTG) - Coronary Artery Bypass Grafting | Not applicable | Completed | Muhammad Aamir Latif | 58 | 2024-01-01 | 2024-10-15 |
| High Versus Low Dose Nitroglycerin in Acute Pulmonary Edema Nitroglycerin - Pulmonary Edema | Phase 2 / Phase 3 | Unknown | Alexandria University | 60 | 2023-11-10 | 2023-10-30 |
| Effect of Stellate Ganglion Block on Internal Mammary Artery Dynamics Left stellate ganglion block, Topical Nitroglycerine - Anesthesia | Not applicable | Completed | Ain Shams University | 70 | 2023-08-08 | 2025-06-03 |
| Study of the Glymphatic System in Migraine Nitroglycerin 0.3 MG, MRI, Blood sampling - Migraine | Recruiting | IRCCS San Raffaele | 50 | 2023-04-30 | 2026-11-06 | |
| Effect of Glyceroltrinitrate on Human Energy Expenditure and Brown Adipose Tissue Thermogenesis Glyceroltrinitrat - Brown Adipose Tissue | Early Phase 1 | Completed | University Hospital, Basel, Switzerland | 30 | 2023-03-01 | 2025-07-29 |
| Nitroglycerin Plus Radiotherapy Versus Conventional Radiotherapy in Patients With Lung Cancer. Nitroglycerin - Non-small Cell Lung Cancer, Brain Metastases | Not applicable | Recruiting | Instituto Nacional de Cancerologia de Mexico | 74 | 2023-02-23 | 2026-04-09 |
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Hypertension (10) · Raynaud Disease (8) · Coronary Artery Disease (7) · Angina Pectoris (6) · Aneurysm (5) · Angina, Stable (5) · Coronary Disease (5) · Fissure in Ano (5) · Scleroderma, Diffuse (5) · Carcinoma, Non-Small-Cell Lung (4) · Cerebral Hemorrhage (4) · Erectile Dysfunction (4) · Heart Failure (4) · Hypotension (4) · Migraine Disorders (4)
MediQuest Therapeutics (8) · Ain Shams University (5) · Mansoura University (4) · Futura Medical Developments Ltd. (3) · Guang'anmen Hospital of China Academy of Chinese Medical Sciences (3) · Medical University of Vienna (3) · Seoul National University Hospital (3) · The George Institute (3) · University of California, San Francisco (3) · Cairo University (2) · Danish Headache Center (2) · Hermina Heart Center Kemayoran (2) · Instituto de Cardiologia de Santa Catarina (2) · Mahidol University (2) · Minia University (2)
United States (38) · Egypt (17) · China (12) · United Kingdom (10) · Denmark (6) · Pakistan (6) · Canada (5) · Netherlands (5) · Austria (4) · Belgium (4) · Italy (4) · South Korea (4) · Australia (3) · Brazil (3) · France (3)
Ben He, MD,PhD (2) · Bruce B Allan, MD PhD (2) · Craig Anderson, PhD (2) · Italo Biaggioni, MD (2) · Jun Li, MD (2) · Michael Wolzt, MD (2) · Roberto L da Silva, MD (2) · Abdelrahman Hemeda, Resident (1) · Adel Nada, M.D. (1) · Ahmed S. Abd El-Hamid, Doctorate (1) · Akiko Takeuchi (1) · Andrew Boyle, MBBS, PhD (1) · Anna J Jovanovich, MD (1) · Anne-Marie C. Dingemans, MD PhD (1)
PMID 32640944, PMID 25503550, PMID 25589782, PMID 25657175, PMID 25712944, PMID 25823544, PMID 26746184, PMID 27165954, PMID 27178897, PMID 27919055, PMID 30890109, PMID 31085948, PMID 31829173, PMID 33598552, PMID 38018833, PMID 40541207, PMID 41855454, PMID 42848972, PMID 10395629, PMID 10851208, PMID 11927799, PMID 11934971, PMID 12119802, PMID 12518122, PMID 12923400, PMID 14769323, PMID 15657647, PMID 15738343, PMID 15916656, PMID 16391172, PMID 16533484, PMID 16580291, PMID 16612915, PMID 16923481, PMID 16970804, PMID 18396107, PMID 18426998, PMID 18806012, PMID 19047577, PMID 19140238, PMID 19410035, PMID 19670137, PMID 19684008, PMID 19701035, PMID 19738158, PMID 20823381, PMID 21362524, PMID 21576282, PMID 21678363, PMID 22129475
2009 (1), 2015 (1), 2016 (1), R01HL028843 (1)