12 terminated. 12 Phase 2, 5 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 12 | Terminated 12 |
| Phase 3 | 5 | Terminated 5 |
| Phase 1 | 1 | Terminated 1 |
Follow Septic Shock: new trials by email Literature Review of Septic Shock trials Research Report on Septic Shock
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Early Metabolic Resuscitation for Septic Shock Best Practice, early metabolic resuscitation - Multiple Organ Failure, Septic Shock | Phase 2 | Terminated | M.D. Anderson Cancer Center | 2 | 2019-10-04 | 2024-10-29 |
| Vitamin C, Steroids, and Thiamine, and Cerebral Autoregulation and Functional Outcome in Septic Shock Stress-dose Hydrocortisone plus Vitamin C, isotonic sodium chloride solution placebo plus isotonic sodium chloride solution placebo - Septic Shock | Phase 1 / Phase 2 | Terminated | University of Athens | 26 | 2018-09-06 | 2024-12-19 |
| Resuscitation With Plasma in Surgical and Trauma Patients With Septic Shock Plasma, Balanced crystalloids - Septic Shock | Phase 2 | Terminated | The University of Texas Health Science Center, Houston | 16 | 2018-03-26 | 2022-04-13 |
| Evaluation of Hydrocortisone, Vitamin C and Thiamine for the Treatment of Septic Shock Triple therapy group - Septic Shock, Critical Illness | Phase 2 / Phase 3 | Terminated | Hamad Medical Corporation | 106 | 2018-03-17 | 2021-12-10 |
| Heparin Anticoagulation in Septic Shock Unfractionated heparin, Venous thromboprophylaxis (VTE) - Septic Shock, Vasodilatory Shock | Phase 2 | Terminated | University of Manitoba | 178 | 2018-03-12 | 2022-05-24 |
| Selepressin Evaluation Programme for Sepsis-Induced Shock - Adaptive Clinical Trial selepressin, placebo - Septic Shock | Phase 2 / Phase 3 | Terminated | Ferring Pharmaceuticals | 868 | 2015-07-01 | 2021-04-06 |
| Treatment of Septic Shock by Inhibiting Autodigestion and Preserving Gut Integrity With Enteric LB1148 LB1148, Placebo - Septic Shock | Phase 2 | Terminated | Leading BioSciences, Inc | 8 | 2015-04-01 | 2020-06-01 |
| Esmolol to Treat the Hemodynamic Effects of Septic Shock Esmolol, Saline - Septic Shock, Hypotension | Phase 2 | Terminated | Beth Israel Deaconess Medical Center | 40 | 2015-03-01 | 2021-06-28 |
| Effect of Hydrocortison on Post-ischemic Flow-mediated Dilation and on Thenar Oxygen Saturation in Human Septic Shock. hydrocortison hemisuccinate, placebo followed by hydrocortisone hemisuccinate - Septic Shock, Adult | Phase 2 / Phase 3 | Terminated | Centre Hospitalier Régional d'Orléans | 10 | 2013-11-05 | 2020-02-11 |
| Upregulation of Alpha-1 Receptors Upon Septic Shock? Clonidine, Placebo - Septic Shock | Phase 2 / Phase 3 | Terminated | Direction Centrale du Service de Santé des Armées | 40 | 2013-08-01 | 2017-07-28 |
| The Cooling And Surviving Septic Shock Study (CASS) Mild Induced Hypothermia - Septic Shock | Phase 2 / Phase 3 | Terminated | Danish Procalcitonin Study Group | 433 | 2011-11-01 | 2016-11-22 |
| Simultaneously Using Traditional Chinese Medicine (Si-Ni-Tang) to Treat Septic Shock Patients Si-Ni-Tang/ Placebo of Si-Ni-Tang - Septic Shock | Phase 2 | Terminated | Changhua Christian Hospital | 8 | 2010-09-01 | 2012-05-23 |
Shock, Septic (12) · Sepsis (3) · Multiple Organ Failure (2) · Critical Illness (1) · Hyperlactatemia (1) · Hypotension (1) · Infections (1) · Shock (1) · Systemic Inflammatory Response Syndrome (1) · Tachycardia (1) · Toxemia (1)
Inflammation (12) · Pathologic Processes (12) · Pathological Conditions, Signs and Symptoms (12) · Infections (11) · Shock (11) · Systemic Inflammatory Response Syndrome (11) · Sepsis (9) · Arrhythmias, Cardiac (1) · Cardiac Conduction System Disease (1) · Cardiovascular Diseases (1) · Disease Attributes (1) · Heart Diseases (1) · Metabolic Diseases (1) · Nutritional and Metabolic Diseases (1) · Signs and Symptoms (1)
Ascorbic Acid (2) · Adrenergic beta-Antagonists (1) · Clonidine (1) · Cool-Down Exercise (1) · Glucose (1) · Heparin (1) · Hydrocortisone (1) · Hypothermia, Induced (1) · Parenteral Nutrition (1) · Placebo Effect (1) · Practice Guidelines as Topic (1) · Proteins (1) · Saline Solution (1) · Sodium Chloride (1) · Standard of Care (1)
Beth Israel Deaconess Medical Center (1) · Centre Hospitalier Régional d'Orléans (1) · Changhua Christian Hospital (1) · Danish Procalcitonin Study Group (1) · Direction Centrale du Service de Santé des Armées (1) · Ferring Pharmaceuticals (1) · Hamad Medical Corporation (1) · Leading BioSciences, Inc (1) · M.D. Anderson Cancer Center (1) · The University of Texas Health Science Center, Houston (1) · University of Athens (1) · University of Manitoba (1)
United States (7) · France (3) · Canada (2) · Denmark (2) · Greece (2) · Netherlands (2) · Belgium (1) · Brazil (1) · India (1) · Pakistan (1) · Philippines (1) · Qatar (1) · Taiwan (1)
Adham Mohamed, PharmD (1) · Anand Kumar, MD (1) · Anastasia Kotanidou, MD, PhD (1) · Dean A Fergusson, PhD MHA (1) · Jens Ulrik S Jensen, MD, PhD (1) · Joseph L. Nates, MBA,MD (1) · Mohamed Abdelaty, MD (1) · Ryan Zarychanski, MD MSc (1) · Shuyan Wei, MD (1) · Spyros D Mentzelopoulos, MD, PhD (1) · Spyros G Zakynthinos, MD. PhD (1) · Stylianos Orfanos, MD, PhD (1) · Thierry Boulain, MD (1)
PMID 10722036, PMID 1138591, PMID 11502226, PMID 12454520, PMID 12545007, PMID 12700374, PMID 1607900, PMID 16570523, PMID 18353115, PMID 20332511, PMID 20646908, PMID 21864392, PMID 227054, PMID 23525934, PMID 24484547, PMID 24838355, PMID 25466837, PMID 26771781, PMID 26903338, PMID 27162802, PMID 27695824, PMID 27940189, PMID 28098591, PMID 29325753, PMID 29388815, PMID 30271882, PMID 31577035, PMID 35066509, PMID 36870070, PMID 3928249, PMID 8615361, PMID 8625625
2014 (1), P30CA016672 (1)