9 completed, 2 recruiting, 2 unknown, 1 not yet recruiting. 8 Not applicable, 3 Phase 1, 2 Phase 2, 2 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Completed 6, Recruiting 1, Unknown 1 |
| Phase 1 | 3 | Completed 1, Recruiting 1, Terminated 1 |
| Phase 2 | 2 | Recruiting 1, Terminated 1 |
| Phase 3 | 2 | Completed 2 |
| Phase 4 | 1 | Unknown 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Multi-strain Probiotic Supplement for Digestive Comfort and Well-being in Healthy Women Active: Multi-strain probiotic dietary supplement, Placebo: Placebo - Gastrointestinal Discomfort, Bloating | Not applicable | Recruiting | Daily Nouri | 160 | 2026-09-19 | 2026-09-25 |
| Multidimensional Study of Dyspnea at Rest, During Exertion, Self-induced Through a Virtual Reality Scenario, and Its Placebo Effect in Patients With COPD and Control Subjects. Induced Dyspnea via Inspiratory Muscle Loading, Virtual Reality Sensory Immersion, Placebo and Active Conditions - COPD (Chronic Obstructive Pulmonary Disease) | Not yet recruiting | University of Deusto | 80 | 2026-04-01 | 2026-05-05 | |
| A Treatment for a Form of Age-Related Central Auditory Processing Disorder Consisting of Clemastine Fumarate Plus Engineered Sound Clemastine Fumarate Combined With Engineered Sound, Clemastine Fumarate Combined With Pink Noise, Placebo Drug With Engineered Sound - Central Auditory Processing Disorder, Hearing Impaired (Partially) | Phase 1 / Phase 2 | Recruiting | University of Colorado, Denver | 344 | 2025-03-31 | 2026-04-30 |
| Prophylactic Effects of Agomelatine for Poststroke Depression Agomelatine, Placebo Tablets - Depression, Acute Ischemic Stroke | Phase 4 | Unknown | First Affiliated Hospital, Sun Yat-Sen University | 420 | 2022-10-01 | 2022-07-27 |
| Primary Prevention of Infection by COVID-19 in Workers Group A: oropharygeal spray and immunostimulant emulsion, Group D:Placebo oropharyngeal spray + Placebo taken PO - COVID | Not applicable | Completed | Unidad de Investigación Genética Molecular | 152 | 2021-03-18 | 2021-07-15 |
| Vitamin C, Steroids, and Thiamine, and Cerebral Autoregulation and Functional Outcome in Septic Shock Stress-dose Hydrocortisone plus Vitamin C, isotonic sodium chloride solution placebo plus isotonic sodium chloride solution placebo - Septic Shock | Phase 1 / Phase 2 | Terminated | University of Athens | 26 | 2018-09-06 | 2024-12-19 |
| Use of Budesonide Diluted to Maximum Clinical Treatment of Patients With Chronic Rhinosinusitis With Polyoposis. Budesonide Nasal, Placebos - Chronic Rhinosinusitis (Diagnosis) | Not applicable | Unknown | Universidade Estadual de Londrina | 60 | 2018-08-10 | 2022-09-15 |
| The Effect of Hypnosis on Blood Concentrations of Endocannabinoids Hypnosis, Meditation, Conditioned pain modulation - Hypnosis, Endocannabinoids | Not applicable | Completed | Université de Sherbrooke | 33 | 2017-11-14 | 2018-10-31 |
| Assessment of the Safety, Tolerability and Pharmacodynamics After Administration of One Dose of AZD8601 to Male Patients With Type II Diabetes Mellitus (T2DM) AZD8601+Placebo (SAD), AZD8601+Placebo, Placebo+Placebo - Male Subjects With Type II Diabetes (T2DM) | Phase 1 | Completed | AstraZeneca | 44 | 2016-12-16 | 2020-01-18 |
| Dexmedetomidine and Desflurane Consumption Dexmedetomidine, Placebo, Ondansetron - Anesthesia | Not applicable | Completed | Theodor Bilharz Research Institute | 40 | 2016-02-01 | 2016-11-10 |
| Whey Protein Supplementation Associated With Resistance Training on Health Indicators in Trained Older Women Whey protein-placebo, Placebo-whey protein, Placebo-placebo - Body Composition, Healthy | Not applicable | Completed | Universidade Estadual de Londrina | 66 | 2015-12-08 | 2017-08-14 |
| Efficacy of the Mckenzie Method in Patients With Chronic Non-Specific Low Back Pain Placebo, McKenzie method - Non-specific Chronic Low Back Pain | Not applicable | Completed | Universidade Cidade de Sao Paulo | 148 | 2014-05-01 | 2016-06-10 |
| Effects of Lipoic Acid on Oxidative, Inflammatory and Functional Markers in Asthmatic Patients Lipoic acid, Placebo - Asthma, Allergic Rhinitis | Not applicable | Completed | Centro Universitario de Ciencias de la Salud, Mexico | 55 | 2010-11-01 | 2013-11-08 |
| The Effect of Nexium and Probiotics on Insulin Secretion and Cardiovascular Risk Factors in Patients With Type 2 Diabetes nexium, Yoghurt, placebo+placebo - Type 2 Diabetes | Phase 3 | Completed | Lise Tarnow | 41 | 2008-06-01 | 2012-09-03 |
| Combination Antibiotic Treatment for Reactive Arthritis Caused by Chlamydia Bacteria Doxycycline and Rifampin, Azithromycin and Rifampin, Placebo - Arthritis, Reactive, Reiter Disease | Phase 3 | Completed | University of South Florida | 42 | 2006-05-01 | 2018-11-13 |
Diabetes Mellitus, Type 2 (2) · Agnosia (1) · Arthritis, Reactive (1) · Asthma (1) · Auditory Diseases, Central (1) · Chlamydia Infections (1) · Coronavirus Infections (1) · Depression (1) · Disease (1) · Dyspnea (1) · Hearing Disorders (1) · Hearing Loss (1) · Hearing Loss, Hidden (1) · Hearing Loss, Noise-Induced (1) · Hearing Loss, Sensorineural (1)
Universidade Estadual de Londrina (2) · AstraZeneca (1) · Centro Universitario de Ciencias de la Salud, Mexico (1) · Daily Nouri (1) · First Affiliated Hospital, Sun Yat-Sen University (1) · Lise Tarnow (1) · Theodor Bilharz Research Institute (1) · Unidad de Investigación Genética Molecular (1) · Universidade Cidade de Sao Paulo (1) · University of Athens (1) · University of Colorado, Denver (1) · University of Deusto (1) · University of South Florida (1) · Université de Sherbrooke (1)
United States (3) · Brazil (2) · Canada (2) · Colombia (1) · Egypt (1) · Germany (1) · Greece (1) · Mexico (1) · Spain (1)
Abla El Hadidy, PhD (1) · Achim Klug, PhD (1) · Allan A. Vaag, MD, DMSc (1) · Anastasia Kotanidou, MD, PhD (1) · Barbara A Davis, PhD, RD (1) · Beatriz H Aristizabal, PhD (1) · Fernando R. Siller Lopez, PhD (1) · Guillaume Leonard, Ph.D. (1) · Jinsheng Zeng (1) · John D. Carter, MD (1) · Leonardo OP Costa, PhD (1) · Luciola CM Costa, PhD (1) · Rainard Fuhr, Dr. med. (1) · Samuel A Budoff, PhD, MS (1) · Serge Marchand, Ph.D. (1)
PMID 20155838, PMID 23011351, PMID 25278336, PMID 28701365, PMID 29751507, PMID 30639252, PMID 30658390, PMID 30870778, PMID 31050066
2016 (1), R21AR053646 (1)