45 completed, 11 unknown, 7 terminated, 4 not yet recruiting. 75 Phase 2, 14 Phase 3, 13 Phase 1.
Follow Puerperal Disorders: new trials by email Literature Review of Puerperal Disorders trials Research Report on Puerperal Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Tocilizumab for the Treatment of Refractory Granulomatous Lobular Mastitis Tocilizumab - Granulomatous Lobular Mastitis, Granulomatous Mastitis | Phase 1 / Phase 2 | Not yet recruiting | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 31 | 2026-06-01 | 2026-05-19 |
| Sublingual Oxytocin for the Prevention of Post-partum Hemorrhage Oxytocin sublingual, Oxytocin IM - Post Partum Hemorrhage | Phase 2 | Not yet recruiting | Insud Pharma | 330 | 2026-05-30 | 2026-04-23 |
| Role of Intravenous Calcium to Decrease Blood Loss During Intrapartum Cesarean Section Calcium Chloride, Placebo - Post Partum Haemorrhage, Cesarean Section Surgery | Phase 2 | Not yet recruiting | Pak Emirates Military Hospital | 182 | 2026-05-01 | 2026-04-24 |
| Antibiotics vs Corticosteroids in Treatment of Granulomatous Lobular Mastitis Steroid, Antibiotic - Granulomatous Mastitis | Phase 1 / Phase 2 | Not yet recruiting | All India Institute of Medical Sciences, Bhubaneswar | 72 | 2026-03-15 | 2026-03-06 |
| The Perinatal Synergistic Multi-component Intervention to alLeviate dEpressive Symptoms. A Case Series interpersonal psychotherapy (IPT), Ketamine - Postpartum Depression | Phase 2 / Phase 3 | Withdrawn | Washington University School of Medicine | 2025-10-15 | 2025-10-29 | |
| Oxytocin Pharmacokinetics and Pharmacodynamics deuterated oxytocin (d5OT) - Post Partum Hemorrhage, Cesarean Section Complications | Phase 2 | Recruiting | Stanford University | 100 | 2025-01-01 | 2026-08-21 |
| High Or Low Dose pOstpartUm Oxytocin at the Time of Cesarean Birth Oxytocin - Postpartum Hemorrhage, Pregnancy Complications | Phase 2 | Withdrawn | University of Chicago | 2024-10-01 | 2024-12-10 | |
| Efficacy of MI078 Capsules in Treating Postpartum Depression MI078 capsule dose 1, MI078 capsule dose 2, placebo - Postpartum Depression | Phase 2 | Completed | Nanjing Minova Pharmaceutical Co., Ltd. | 72 | 2024-09-09 | 2026-06-25 |
| RE104 Safety and Efficacy Study in Postpartum Depression RE104 for Injection - Postpartum Depression | Phase 2 | Completed | Reunion Neuroscience Inc | 84 | 2024-06-14 | 2026-05-14 |
| A Study to Assess the Efficacy, Safety, and Tolerability of Oral NORA520 in Adults With Severe Postpartum Depression NORA520 Dose 1, NORA520 Dose 2, Placebo - Depression, Postpartum, Postpartum Depression | Phase 2 | Completed | TWi Biotechnology, Inc. | 93 | 2024-03-28 | 2026-07-31 |
| A Study of BRII-296 in Adults With Severe Postpartum Depression (PPD) BRII-296, Depo Medrol - Severe Postpartum Depression | Phase 2 | Completed | Brii Biosciences Limited | 11 | 2023-09-29 | 2025-01-27 |
| A Phase II Study of HS-10353 in Participants With Postpartum Depression HS-10353 Capsules 30 mg, Oral, QN for 14 days, HS-10353 Capsules 50 mg, Oral, QN for 14 days, HS-10353 Capsules matching placebo, 30mg, Oral, QN for 14 days. - Postpartum Depression | Phase 2 | Unknown | Jiangsu Hansoh Pharmaceutical Co., Ltd. | 96 | 2023-08-31 | 2023-07-10 |
| Efficacy of Carbetocin in Prevention of Postpartum Hemorrhage in Obese Versus Non Obese Women Carbetocin 100 Microgram/mL Solution for Injection - Obesity, Maternal, Post Partum Hemorrhage | Phase 1 / Phase 2 | Completed | Cairo University | 150 | 2023-07-06 | 2024-01-22 |
| Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women MWSH plus Candlelit Care, MWSH - Pregnancy Related, Pregnancy Complications | Phase 2 / Phase 3 | Active not recruiting | Cedars-Sinai Medical Center | 150 | 2023-06-01 | 2026-10-22 |
| Phase 2 Clinical Trial of GH001 in Postpartum Depression GH001 - Postpartum Depression, Postnatal Depression | Phase 2 | Terminated | GH Research Ireland Limited | 10 | 2023-03-02 | 2025-02-18 |
| Prevention of Postpartum Hemorrhage With Tranexamic Acid Tranexamic acid, No intervention - Post Partum Hemorrhage | Phase 2 | Recruiting | Inova Health Care Services | 120 | 2022-12-28 | 2026-10-16 |
| The SUPPORT Study: Effectiveness and Usability of a Web-Enabled Resource for Postpartum Mental Health Postpartumcare.ca (Web-Enabled Intervention) - Postpartum Depression, Postpartum Anxiety | Phase 2 | Completed | University of British Columbia | 103 | 2022-04-20 | 2023-05-10 |
| Prevention of Primary Postpartum Haemorrhage Misoprostol, Oxytocin - Primary, Post Partum Hemorrhage | Phase 2 | Unknown | Islamabad Medical and Dental College | 180 | 2021-02-03 | 2021-02-25 |
| Maternal Mental Health Trial Transdermal patch estradiol, Transdermal patch placebo - Major Depressive Disorder, Postpartum Depression | Phase 1 / Phase 2 | Recruiting | Vibe G Frøkjær, MD, PhD | 220 | 2021-02-03 | 2021-09-23 |
| A Program to Evaluate Riastap® and FIBTEM® for the Early Control and Treatment of Postpartum Hemorrhage (PERFECT PPH) fibrinogen concentrate, Placebo - Postpartum Hemorrhage | Phase 1 / Phase 2 | Withdrawn | Yale University | 2021-01-01 | 2021-03-15 |
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Postpartum Hemorrhage (34) · Depression, Postpartum (33) · Depression (11) · Hemorrhage (5) · Pregnancy Complications (4) · Anxiety Disorders (3) · Mental Disorders (3) · Mood Disorders (3) · Anemia (2) · Behavioral Symptoms (2) · Breast Feeding (2) · Depressive Disorder (2) · Granulomatous Mastitis (2) · Mastitis (2)
Female Urogenital Diseases and Pregnancy Complications (75) · Urogenital Diseases (75) · Pregnancy Complications (71) · Pathological Conditions, Signs and Symptoms (38) · Pathologic Processes (35) · Obstetric Labor Complications (34) · Uterine Hemorrhage (34) · Depressive Disorder (31) · Mental Disorders (30) · Mood Disorders (30) · Hemorrhage (29) · Behavior (15) · Behavioral Symptoms (10) · Signs and Symptoms (6)
Misoprostol (11) · Oxytocin (11) · Tranexamic Acid (8) · Estradiol (3) · Ketamine (3) · Sodium Chloride (3) · Fibrinogen (2) · Injections (2) · Interpersonal Psychotherapy (2) · Leuprolide (2) · Progesterone (2) · Saline Solution (2) · brexanolone (2) · carbetocin (2) · ganaxolone (2)
Ain Shams University (3) · Cairo University (3) · Ain Shams Maternity Hospital (2) · Assiut University (2) · Benha University (2) · Marinus Pharmaceuticals (2) · Massachusetts General Hospital (2) · National Institute of Mental Health (NIMH) (2) · Pakistan Institute of Living and Learning (2) · Qazvin University Of Medical Sciences (2) · Supernus Pharmaceuticals, Inc. (2) · Universidad Complutense de Madrid (2) · University of North Carolina, Chapel Hill (2) · Women and Infants Hospital of Rhode Island (2) · Aga Khan University (1)
United States (26) · Egypt (11) · Pakistan (5) · Iran (4) · Canada (3) · China (3) · Denmark (2) · Spain (2) · Bangladesh (1) · Brazil (1) · Germany (1) · India (1) · Iraq (1) · Netherlands (1) · Nigeria (1)
Peter J Schmidt, M.D. (2) · Stephen J Kanes, MD, PhD (2) · Abubaker M Elnashar, MD (1) · Alison M Stuebe, MD, MSc (1) · Amgad E. Abou-Gamrah, Ass.Prof. (1) · Aminur Rahman, MBBS,MSc (1) · Amr Yehia, MD, MRCOG (1) · Anna Palatnik, MD (1) · Anne J. Wikkelsoe, MD (1) · Arash Afshari, MD (1) · Ariana Kh. Jawad, Assistant professor (1) · Arunporn Itharat, PH.D. (1) · Ashish Premkumar, MD, PhD (1)
PMID 10467792, PMID 10908457, PMID 11502292, PMID 14600674, PMID 15954876, PMID 16390366, PMID 16581405, PMID 16842791, PMID 17197859, PMID 17634155, PMID 17650319, PMID 19432563, PMID 19943825, PMID 20009308, PMID 20187965, PMID 20455694, PMID 20884642, PMID 22540529, PMID 22805300, PMID 22882240, PMID 24880136, PMID 25586727, PMID 26454186, PMID 26611780, PMID 28480799, PMID 28619476, PMID 28707488, PMID 29025850, PMID 29316912, PMID 30447565, PMID 31598047, PMID 32609374, PMID 32987448, PMID 33064852, PMID 33078388, PMID 33181049, PMID 33248975, PMID 33705565, PMID 35038612, PMID 35141873, PMID 35763351, PMID 36934142, PMID 37491196, PMID 37626292, PMID 37883133, PMID 37990597, PMID 38709329, PMID 38767196, PMID 39732915, PMID 40113655
2008 (1), 2009 (1), K23HL141640 (1), K23MH066265 (1), KL2TR001877 (1), R01HD093901 (1), R01HD110109 (1), R01MH071766 (1), R01MH074636 (1), R01MH074919 (1), R21HD090396 (1), R21MD017396 (1), R21MH085176 (1), R21MH119615 (1), UL1TR001876 (1)