4 completed, 2 recruiting, 2 terminated, 1 unknown. 10 Phase 2, 4 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Completed 4, Recruiting 2, Terminated 2, Unknown 1, Withdrawn 1 |
| Phase 3 | 4 | Completed 2, Recruiting 1, Terminated 1 |
Follow Prematurity: new trials by email Literature Review of Prematurity trials Research Report on Prematurity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Caffeine as an Adjuvant Therapy for Late Preterm Infants With Respiratory Distress Caffeine citrate, Placebo - Prematurity, Respiratory Disease | Phase 2 / Phase 3 | Recruiting | Ministry of Health, Saudi Arabia | 134 | 2023-10-12 | 2025-06-27 |
| Darbe Plus IV Iron to Decrease Transfusions While Maintaining Iron Sufficiency in Preterm Infants Darbepoetin Alfa, Low Molecular Weight Iron Dextran, Ferumoxytol injection - Prematurity, Iron-deficiency | Phase 2 | Recruiting | University of Washington | 120 | 2022-11-27 | 2026-05-26 |
| Prediction of NEC With Urinary iFABP Assessment of urinary iFABP, Administration of enteral feedings - Prematurity, Necrotizing Enterocolitis | Phase 2 | Withdrawn | Loma Linda University | 2014-11-01 | 2015-05-14 | |
| Initiation of Oral Feeding at 30 Versus 33 Weeks Postmenstrual Age Oral feeding - Prematurity | Phase 2 / Phase 3 | Completed | The University of Texas Health Science Center, Houston | 66 | 2013-01-01 | 2016-05-13 |
| Effect of Early L-Carnitine Supplementation on Neurodevelopmental Outcomes in Very Preterm Infants L-carnitine, 5% Dextrose - Prematurity, Neurodevelopmental Disorder | Phase 2 / Phase 3 | Completed | Montefiore Medical Center | 144 | 2013-01-01 | 2023-03-08 |
| Early Supplementation of Enteral Microlipid With and Without Fish Oil in Premature Infants With Enterostomies Microlipid with fish oil, Microlipid - Prematurity, Intestine Perforation | Phase 2 | Completed | Wake Forest University | 18 | 2012-10-01 | 2018-12-04 |
| Dexamethasone for Preterm Labour Dexamethasone 24 hours, Dexamethasone 12 - Prematurity | Phase 2 | Completed | Assiut University | 200 | 2012-01-01 | 2012-10-02 |
| Inhaled Prostaglandin E1 (IPGE1) for Hypoxemic Respiratory Failure (NHRF) Aerosolized Normal Saline, Inhaled PGE1 - Prematurity, Respiratory Insufficiency | Phase 2 | Terminated | NICHD Neonatal Research Network | 7 | 2011-11-01 | 2019-04-24 |
| Skin-to-skin Contact to Promote Bacterial Decolonization in Preterm Infants skin-to skin contact - PREMATURITY | Phase 2 | Unknown | Universidade Federal do Maranhão | 102 | 2008-05-01 | 2011-12-23 |
| Inhaled Nitric Oxide and Neuroprotection in Premature Infants inhaled nitric oxide, oxygen - Prematurity, Bronchopulmonary Dysplasia | Phase 2 / Phase 3 | Terminated | University of Chicago | 273 | 2008-05-01 | 2024-10-17 |
Premature Birth (10) · Bronchopulmonary Dysplasia (2) · Enterocolitis, Necrotizing (2) · Anemia (1) · Anemia, Iron-Deficiency (1) · Dyspnea (1) · Hypertension, Pulmonary (1) · Intestinal Perforation (1) · Iron Deficiencies (1) · Leukomalacia, Periventricular (1) · Neurodevelopmental Disorders (1) · Obstetric Labor, Premature (1) · Respiration Disorders (1) · Respiratory Distress Syndrome, Newborn (1) · Respiratory Insufficiency (1)
Female Urogenital Diseases and Pregnancy Complications (10) · Obstetric Labor Complications (10) · Pregnancy Complications (10) · Urogenital Diseases (10) · Obstetric Labor, Premature (9) · Respiratory Tract Diseases (4) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Infant, Newborn, Diseases (3) · Infant, Premature, Diseases (3) · Lung Diseases (3) · Cardiovascular Diseases (2) · Digestive System Diseases (2) · Enterocolitis (2) · Gastroenteritis (2) · Gastrointestinal Diseases (2)
Carnitine (1) · Darbepoetin alfa (1) · Dexamethasone (1) · Ferrosoferric Oxide (1) · Fish Oils (1) · Glucocorticoids (1) · Glucose (1) · Iron-Dextran Complex (1) · Kangaroo-Mother Care Method (1) · Oxygen (1) · Safflower Oil (1) · Saline Solution (1) · Sodium Chloride (1) · caffeine citrate (1)
Assiut University (1) · Loma Linda University (1) · Ministry of Health, Saudi Arabia (1) · Montefiore Medical Center (1) · NICHD Neonatal Research Network (1) · The University of Texas Health Science Center, Houston (1) · Universidade Federal do Maranhão (1) · University of Chicago (1) · University of Washington (1) · Wake Forest University (1)
United States (7) · Brazil (1) · Egypt (1) · Saudi Arabia (1)
Abhik Das, PhD (1) · Beena Sood, MD (1) · C. Michael Cotten, MD (1) · Fernando Lamy Filho, PhD (1) · Gerald Gollin, MD (1) · Jonathan M Klein, MD (1) · Kendell R German, MD (1) · Krisa P Van Meurs, MD (1) · Leif Nelin, MD (1) · Mamta Fuloria, MD (1) · Martin Keszler, MD (1) · Michael D. Schreiber, M.D. (1) · Namasivayam Ambalavanan, MD (1) · Nehad Nasef (1) · Pablo J Sanchez, MD (1)
PMID 20980771, PMID 23453547, PMID 25496504, PMID 25880822, PMID 41430711
R01HD107003 (1), U10HD021385 (1), U10HD027880 (1), U10HD027904 (1), U10HD034216 (1), U10HD036790 (1), U10HD040461 (1), U10HD040492 (1), U10HD040689 (1), U10HD053109 (1), U10HD068263 (1), U10HD068270 (1), U10HD068278 (1)