19 completed, 10 unknown, 2 active not recruiting, 2 not yet recruiting. 9 Not applicable, 4 Phase 2, 2 Phase 3, 1 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 9 | Completed 5, Unknown 4 |
| Phase 2 | 4 | Completed 4 |
| Phase 3 | 2 | Completed 1, Terminated 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 4 | 1 | Active not recruiting 1 |
Follow Intestinal Perforation: new trials by email Literature Review of Intestinal Perforation trials Research Report on Intestinal Perforation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Saudi Emergency Laparotomy Audit Emergency Laparotomy - Laparotomy, Laparotomy Surgery | Not yet recruiting | King Faisal Specialist Hospital & Research Center | 10000 | 2026-06-01 | 2026-02-24 | |
| Prevention of Postoperative Hernias in Emergency Surgery Incarcerated Hernia, Appendicitis Acute | Recruiting | Jan Kochanowski University | 500 | 2025-06-01 | 2025-06-15 | |
| Enhanced Recovery Versus Standard Care After Emergency Abdominal Surgery in Patients Requiring Emergency Laparotomy Enhanced Recovery After Surgery, Conventional Postoperative Care - Emergency Laparotomy, Intestinal Obstruction | Not applicable | Completed | Recep Tayyip Erdogan Hospital Pakistan - Muzaffargarh | 102 | 2025-05-01 | 2026-06-16 |
| Early Hydrocortisone Versus Regular Treatment in Shock in Extremely Preterm Neonates - an Open Randomized Controlled Trial Intravascular Hydrocortisone (stress dosage): 1 mg/k/dose each 8 hours for 5 days, Vasoactive drug therapies - Shock, Preterm Birth Complication | Phase 4 | Active not recruiting | Coordinación de Investigación en Salud, Mexico | 76 | 2025-02-01 | 2025-11-25 |
| Necrotizing Enterocolitis and Bowel Perforation in Very Preterm Infants - Long-term Follow up Necrotizing Enterocolitis, Intestinal Perforation | Not yet recruiting | University Hospital of North Norway | 150 | 2025-02-01 | 2025-01-03 | |
| Effect of Early Hydrocortisone on Risk of Gastrointestinal Perforations in Extremely Preterm Infants Hydrocortisone - Intestinal Perforation | Active not recruiting | Imperial College London | 16000 | 2024-07-30 | 2024-10-03 | |
| Soluble Immune Checkpoints in Intra-Abdominal Infections Soluble Immune checkpoint levels - Intra Abdominal Infections | Completed | Istanbul Training and Research Hospital | 75 | 2023-12-01 | 2026-07-08 | |
| Safety and Feasibility of Indocyanine Green Fluorescence for Intraoperative Assessment of Intestinal Perfusion in Young Infants and Neonates Perfusion assessment by means of the SPY-PHI camera - NEC, Atresia | Not applicable | Unknown | University Medical Center Groningen | 20 | 2023-08-01 | 2023-05-12 |
| Analysis of Integrated Clinical, Laboratory and Prognostic Data of Neonates With Necrotizing Enterocolitis Observational retrospective cohort study - Necrotizing Enterocolitis | Completed | Sixth Affiliated Hospital, Sun Yat-sen University | 400 | 2023-01-01 | 2026-03-02 | |
| Effect of Implementation of the Danish Emergency Surgery (DANAKIR) Support Network on Post-discharge Outcomes After Major Emergency Abdominal Surgery DANAKIR support network - Bowel Perforated, Bowel Obstruction | Unknown | Herlev Hospital | 400 | 2022-09-01 | 2022-07-07 | |
| Evaluation of the Clinical Utility of Endoscopic Closure Using a Dual Action Tissue (DAT) Clip DAT Clip - GI Bleeding, Perforation Colon | Recruiting | AdventHealth | 250 | 2022-08-31 | 2026-10-15 | |
| Impact of Abdominal Drains on the ERAS Pathway in Peptic Perforation ERAS protocol - Perforated Peptic Ulcer, Fast Track Surgery | Not applicable | Unknown | All India Institute of Medical Sciences, Bhubaneswar | 92 | 2022-06-15 | 2023-02-06 |
| Neokare Safety and Tolerability Assessment in Neonates With GI Problems NeoKare Breast Milk Fortifier - NEC, Gastroschisis | Unknown | University Hospital Southampton NHS Foundation Trust | 50 | 2022-06-09 | 2022-10-28 | |
| COMPARISON OF CONTINUOUS VERSUS INTERRUPTED-X SUTURING TECHNIQUE FOR CLOSURE OF RECTUS SHEATH IN PATIENTS UNDERGOING EMERGENCY LAPAROTOMY FOR HOLLOW VISCUS PERFORATION Continuous suturing, Interrupted X suturing - Duodenal Perforation, Bowel Perforated | Not applicable | Unknown | King Edward Medical University | 86 | 2022-06-02 | 2022-11-30 |
| Direct Peritoneal Resuscitation for Intra-abdominal Catastrophes there is no intervention involved in this study - Intestinal Perforation, Intestinal Obstruction | Unknown | New York Medical College | 108 | 2021-12-16 | 2022-01-26 | |
| TyVECO: Surveillance Protocol Typbar-TCV, Bharat Biotech - Typhoid Fever, Intestinal Perforation | Unknown | International Vaccine Institute | 48000 | 2021-08-09 | 2022-09-30 | |
| Timing of Stoma Closure in Neonates No intervention - observational study - Enterocolitis, Necrotizing, Atresia; Bowel | Completed | Manchester University NHS Foundation Trust | 56 | 2021-02-17 | 2023-01-18 | |
| The Best Care for Abdominal Emergencies Study Laparotomy or laparoscopy - Acute Abdomen, Bowel Obstruction | Completed | Portsmouth Hospitals NHS Trust | 2500 | 2021-01-08 | 2025-12-26 | |
| The Role of Indocyanine Green Angiography Fluorescence on Intestinal Resections in Pediatric Surgery. SPY imaging, Indocyanine Green - Intestinal Atresia, Necrotizing Enterocolitis | Not applicable | Completed | St. Justine's Hospital | 35 | 2020-03-16 | 2021-03-17 |
| ERAS vs Conventional Approach in Peptic Perforation-RCT Enhanced Recovery after Surgery group, Conventional - Peptic Ulcer Perforation, Perforated Bowel | Not applicable | Completed | All India Institute of Medical Sciences, Bhubaneswar | 60 | 2020-01-20 | 2022-03-18 |
Showing 20 of 36. Sign in to see all of them.
Enterocolitis, Necrotizing (10) · Intestinal Obstruction (8) · Premature Birth (8) · Ileus (6) · Postoperative Complications (5) · Peritonitis (4) · Abdomen, Acute (3) · Gastroschisis (3) · Intestinal Atresia (3) · Meconium Ileus (3) · Sepsis (3) · Appendicitis (2) · Emergencies (2) · Hirschsprung Disease (2)
Digestive System Diseases (36) · Intestinal Diseases (36) · Gastrointestinal Diseases (35) · Pathological Conditions, Signs and Symptoms (19) · Gastroenteritis (13) · Pathologic Processes (13) · Enterocolitis (10) · Female Urogenital Diseases and Pregnancy Complications (9) · Infections (9) · Urogenital Diseases (9) · Obstetric Labor Complications (8) · Obstetric Labor, Premature (8) · Pregnancy Complications (8) · Pathological Conditions, Anatomical (6) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (5)
Laparotomy (2) · Amoxicillin-Potassium Clavulanate Combination (1) · Anti-Inflammatory Agents, Non-Steroidal (1) · Bupivacaine (1) · Colectomy (1) · Congresses as Topic (1) · Doripenem (1) · Drainage (1) · Enhanced Recovery After Surgery (1) · Fish Oils (1) · Hydrocortisone (1) · Indocyanine Green (1) · Laparoscopy (1) · Liver Transplantation (1) · Meropenem (1)
All India Institute of Medical Sciences, Bhubaneswar (2) · NICHD Neonatal Research Network (2) · AdventHealth (1) · Baylor Research Institute (1) · Children's Hospitals and Clinics of Minnesota (1) · Coordinación de Investigación en Salud, Mexico (1) · Copenhagen University Hospital, Hvidovre (1) · Dan E. Azagury (1) · Herlev Hospital (1) · Imperial College London (1) · International Vaccine Institute (1) · Istanbul Training and Research Hospital (1) · Jan Kochanowski University (1) · Janssen Research & Development, LLC (1) · KU Leuven (1)
United States (11) · United Kingdom (5) · India (2) · Pakistan (2) · Sweden (2) · Turkey (Türkiye) (2) · Argentina (1) · Belgium (1) · Brazil (1) · Canada (1) · Chile (1) · China (1) · Colombia (1) · Democratic Republic of the Congo (1) · Denmark (1)
Abbot R. Laptook, MD (2) · Richard A. Ehrenkranz, MD (2) · Seetha Shankaran, MD (2) · Waldemar A. Carlo, MD (2) · Abhik Das, PhD (1) · Avroy A. Fanaroff, MD (1) · Barbara J. Stoll, MD (1) · Barbara Schmidt, MD, MSc (1) · Bartosz Molasy, MD, PhD (1) · Brad Yoder, MD (1) · Brenda Poindexter, MD, MS (1) · Brian C. Weiner, MD (1) · C. Michael Cotten, MD (1) · Carl D'Angio, MD (1)
PMID 24119887, PMID 14599604, PMID 15912048, PMID 16549503, PMID 16967294, PMID 19524719, PMID 20980771, PMID 22929145, PMID 23095627, PMID 23453547, PMID 25171544, PMID 25384994, PMID 26056530, PMID 26169030, PMID 27509704, PMID 28112798, PMID 28653239, PMID 30340932, PMID 30842811, PMID 30850756, PMID 30864508, PMID 31255386, PMID 32117838, PMID 32336643, PMID 32433511, PMID 32855507, PMID 34380437, PMID 35008115, PMID 35313308, PMID 36200375, PMID 36535423, PMID 36647120, PMID 37169336, PMID 37481003, PMID 37794545, PMID 38564081, PMID 38955846, PMID 39131150, PMID 39834496, PMID 39905329, PMID 40703916
M01RR008084 (2), U10HD021364 (2), U10HD021373 (2), U10HD021385 (2), U10HD027851 (2), U10HD027853 (2), U10HD027856 (2), U10HD027871 (2), U10HD027880 (2), U10HD027904 (2), U10HD034216 (2), U10HD036790 (2), U10HD040492 (2), U10HD040689 (2), 2009 (1)