50 completed, 14 terminated, 13 recruiting, 9 withdrawn. 20 Phase 3, 18 Phase 2, 16 Phase 1, 14 Not applicable, 12 Early Phase 1.
Follow Ferrosoferric Oxide: new trials by email Literature Review of Ferrosoferric Oxide trials Research Report on Ferrosoferric Oxide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Nanozymes in Endodontics Nanozyme treatment, Control (Standard treatment) - Apical Periodontitis, Endodontic Disease | Phase 4 | Enrolling by invitation | University of Pennsylvania | 72 | 2026-08-24 | 2026-10-13 |
| Ferumoxytol-enhanced Magnetic Resonance Venography in Patients With Venous Diseases Ferumoxytol injection - Venous Diseases | Phase 2 | Recruiting | Min Zhou | 50 | 2026-03-08 | 2026-03-11 |
| Handheld MPI Imaging to Track Stem Cells in Osteoarthritis Human Umbilical Cord-derived Mesenchymal Stromal Cells (hUC-MSCs), Ferumoxytol (SPIO) Solution for Injection (Placebo) - Knee Arthritis Osteoarthritis | Early Phase 1 | Enrolling by invitation | Soochow University | 10 | 2025-12-16 | 2026-05-12 |
| Advanced Imaging Techniques for Evaluating the Tumor Immune Microenvironment in Glioblastoma Patients Biospecimen Collection, Chemical Exchange Saturation Transfer Magnetic Resonance Imaging, Diffusion-Relaxation Correlation Spectrum Imaging - Glioblastoma | Phase 3 | Recruiting | Jonsson Comprehensive Cancer Center | 15 | 2025-10-27 | 2026-03-10 |
| Virtual Histology of the Bladder Wall for Bladder Cancer Staging Magnetic Resonance Imaging, Gadobutrol intravesical administration (4mM), Ferumoxytol intravesical administration (5 mM) - Urinary Bladder Neoplasms | Early Phase 1 | Recruiting | Jodi Maranchie | 42 | 2025-05-23 | 2025-12-17 |
| Enhanced MRI Imaging in Healthy Participants and Participants With Epilepsy Ferumoxytol - Epilepsy, Temporal Lobe | Phase 2 | Recruiting | University of Alberta | 50 | 2025-05-01 | 2026-05-08 |
| Calculating Wall Shear Stress in Infant Pulmonary Veins Ferumoxytol - Pulmonary Vein Stenosis | Phase 1 | Recruiting | Children's Hospital of Philadelphia | 20 | 2024-09-30 | 2026-08-05 |
| A Novel Ferumoxytol-enhanced Cardiac Magnetic Resonance for the Detection of Calcified Coronary Arteries Superparamagnetic Iron Oxide Nanoparticles - Coronary Artery Calcification | Recruiting | The First Affiliated Hospital with Nanjing Medical University | 100 | 2024-01-26 | 2026-02-10 | |
| A Novel Ferumoxytol-enhanced Cardiac Magnetic Resonance Imaging for the Detection of Intracardiac Thrombus Superparamagnetic Iron Oxide Nanoparticles - Heart Aneurysm | Unknown | The First Affiliated Hospital with Nanjing Medical University | 320 | 2023-11-06 | 2024-09-23 | |
| A Safety Study of Pharmacologic Ascorbate and Ferumoxytol in Addition to Standard of Care Chemoradiation in Glioblastoma Ferumoxytol injection, Pharmacological ascorbate, External beam radiation therapy - Glioblastoma, Glioblastoma Multiforme | Phase 1 | Active not recruiting | Bryan Allen | 16 | 2023-02-28 | 2026-07-20 |
| Darbe Plus IV Iron to Decrease Transfusions While Maintaining Iron Sufficiency in Preterm Infants Darbepoetin Alfa, Low Molecular Weight Iron Dextran, Ferumoxytol injection - Prematurity, Iron-deficiency | Phase 2 | Recruiting | University of Washington | 120 | 2022-11-27 | 2026-05-26 |
| Novel Imaging Markers in SPMS Ferumoxytol infusion, Gadoteridol, MRI Brain and Cervical Spine - Secondary Progressive Multiple Sclerosis, Multiple Sclerosis, Secondary Progressive | Early Phase 1 | Completed | University of Utah | 11 | 2022-06-01 | 2026-08-13 |
| Early Antenatal Support for Iron Deficiency Anemia Ferumoxytol, Ferrous Sulfate - Pregnancy Related, Anemia, Iron Deficiency | Phase 4 | Recruiting | Thomas Jefferson University | 80 | 2021-09-29 | 2025-12-02 |
| Assessment of Renal Vasculature and Function with Ferumoxytol-enhanced Magnetic Resonance Imaging domestic polysaccharide superparamagnetic iron oxide nanoparticle - Chronic Kidney Diseases | Phase 1 | Completed | The First Affiliated Hospital with Nanjing Medical University | 44 | 2021-09-17 | 2024-09-25 |
| Placental Lesions in Fetal Growth Restrictions Ferumoxytol infusion, MRI scan - Fetal Growth Retardation | Early Phase 1 | Completed | University of Wisconsin, Madison | 3 | 2021-04-15 | 2025-08-22 |
| Comparison of Oral Ferrous Sulfate to Intravenous Ferumoxytol in Antepartum Iron Deficiency Anemia Ferumoxytol Injection [Feraheme], Ferrous Sulfate - Pregnancy Related, Anemia, Iron Deficiency | Phase 3 | Completed | Stanford University | 83 | 2021-01-21 | 2026-06-30 |
| Radiotherapy With Iron Oxide Nanoparticles (SPION) on MR-Linac for Primary & Metastatic Hepatic Cancers Ferumoxytol injection - Liver Neoplasms, Hepatic Cirrhosis | Unknown | Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) | 40 | 2020-11-19 | 2024-01-31 | |
| Predicting Stroke Risk in ICAD With Novel MRI Feraheme - Intracranial Atherosclerosis | Phase 4 | Withdrawn | Northwestern University | 2020-09-01 | 2026-08-06 | |
| A New Clinical Use of Ferumoxytol Nanoparticles: An Antibiofilm Treatment Iron oxide nanoparticles treatment Ferumoxytol/H2O2, NaOCl, NaCl - Apical Periodontitis, Pulp Disease, Dental | Phase 4 | Completed | University of Pennsylvania | 44 | 2020-07-13 | 2024-08-28 |
| Trial of IV vs Oral Iron Treatment of Iron Deficiency Anemia in the Post-Operative Bariatric Surgical Patient Ferumoxytol, Saline, Ferrous sulfate tablets - Iron Deficiency Anemia | Phase 3 | Recruiting | Auerbach Hematology Oncology Associates P C | 104 | 2020-02-27 | 2025-10-03 |
Showing 20 of 94. Sign in to see all of them.
Anemia, Iron-Deficiency (20) · Anemia (11) · Brain Neoplasms (6) · Renal Insufficiency, Chronic (6) · Glioblastoma (5) · Esophageal Neoplasms (3) · Multiple Sclerosis (3) · Prostatic Neoplasms (3) · AIDS Dementia Complex (2) · Colorectal Neoplasms (2) · Coronary Artery Disease (2) · Dental Pulp Diseases (2) · Head and Neck Neoplasms (2) · Inflammation (2) · Intracranial Arteriosclerosis (2)
AMAG Pharmaceuticals, Inc. (17) · OHSU Knight Cancer Institute (14) · Stanford University (4) · National Cancer Institute (NCI) (3) · The First Affiliated Hospital with Nanjing Medical University (3) · University of Pennsylvania (3) · Auerbach Hematology Oncology Associates P C (2) · Brigham and Women's Hospital (2) · Dana-Farber Cancer Institute (2) · M.D. Anderson Cancer Center (2) · Massachusetts General Hospital (2) · Michael Iv (2) · Thomas Jefferson University (2) · University of Edinburgh (2) · University of Wisconsin, Madison (2)
United States (75) · Canada (8) · Poland (7) · China (5) · Hungary (5) · United Kingdom (5) · Latvia (4) · Lithuania (4) · India (3) · Germany (2) · Australia (1) · Belgium (1) · Denmark (1) · France (1) · Italy (1)
Edward Neuwelt (4) · Alexander Guimaraes (3) · Andrew M Siedlecki, MD (2) · Dinesh Shah, MD (2) · Edward A Neuwelt (2) · Edward A Neuwelt, MD (2) · Adam de Havenon, MD (1) · Alexander Kirichenko, MD, PhD (1) · Allison O'Neill, MD (1) · Beau K Nakamoto, MD, PhD (1) · Beau Nakamoto, MD, PhD (1) · Bekir Karabucak, DMD, MS (1) · Brian Rutt, PhD (1) · Chunjian Li, Dr,PhD (1) · Chunjian Li, MD, PhD (1)
PMID 22874106, PMID 18084623, PMID 18525001, PMID 18824288, PMID 19176796, PMID 22875883, PMID 23828252, PMID 24458078, PMID 24559803, PMID 26786296, PMID 27465647, PMID 28372549, PMID 28642288, PMID 28986407, PMID 29248659, PMID 30518682, PMID 30802204, PMID 31104505, PMID 31673393, PMID 32368961, PMID 33201358, PMID 34870211, PMID 36734848, PMID 36999999, PMID 37010988, PMID 37348816, PMID 37348817, PMID 37651553, PMID 41430711, PMID 41860281
R01CA137488 (3), U01HD087216 (2), 2009 (1), K08CA237809 (1), K08EB012859 (1), K12HD103084 (1), KL2TR001882 (1), P01AI054904 (1), P30CA069533 (1), P30CA124435 (1), R01CA269231 (1), R01HD107003 (1), R01NS034608 (1), R21CA270742 (1), R21NS087951 (1)