6 completed, 2 terminated, 1 enrolling by invitation, 1 recruiting. 12 Phase 3, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 12 | Completed 6, Terminated 2, Enrolling by invitation 1, Recruiting 1, Unknown 1, Withdrawn 1 |
| Phase 2 | 4 | Completed 2, Recruiting 1, Terminated 1 |
Follow Prematurity: new trials by email Literature Review of Prematurity trials Research Report on Prematurity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Preterm Neonates Brain Ultrasound With CEUS and Elastography Brain contrast enhanced ultrasound, brain ultrasound elastography, Sulfur Hexafluoride - Prematurity | Phase 3 | Withdrawn | Turku University Hospital | 2024-01-01 | 2026-01-15 | |
| Caffeine as an Adjuvant Therapy for Late Preterm Infants With Respiratory Distress Caffeine citrate, Placebo - Prematurity, Respiratory Disease | Phase 2 / Phase 3 | Recruiting | Ministry of Health, Saudi Arabia | 134 | 2023-10-12 | 2025-06-27 |
| LMWH for Treatment of Early Fetal Growth Restriction (HepaGrowth) subcutaneous Enoxaparin, standard of care - Fetal Growth Retardation, Prematurity | Phase 3 | Enrolling by invitation | Centro Hospitalar de Lisboa Central | 12 | 2022-07-18 | 2025-08-13 |
| Intratracheal Budesonide With Surfactant to Prevent Bronchopulmmonary Dysplasia. Poractant Alfa Intratracheal Suspension [Curosurf], Budesonide 0.5 MG/ML - Bronchopulmonary Dysplasia, Respiratory Distress Syndrome in Premature Infant | Phase 3 | Unknown | Hospital Clinic of Barcelona | 50 | 2021-10-01 | 2021-09-13 |
| Initiation of Oral Feeding at 30 Versus 33 Weeks Postmenstrual Age Oral feeding - Prematurity | Phase 2 / Phase 3 | Completed | The University of Texas Health Science Center, Houston | 66 | 2013-01-01 | 2016-05-13 |
| Effect of Early L-Carnitine Supplementation on Neurodevelopmental Outcomes in Very Preterm Infants L-carnitine, 5% Dextrose - Prematurity, Neurodevelopmental Disorder | Phase 2 / Phase 3 | Completed | Montefiore Medical Center | 144 | 2013-01-01 | 2023-03-08 |
| Oral Vitamin A Supplementation for Prevention of Bronchopulmonary Dysplasia in Preterm Infants Vitamin A - Bronchopulmonary Dysplasia (BPD), Prematurity | Phase 3 | Completed | Erhan Calisici | 209 | 2012-03-01 | 2026-05-11 |
| Reduction of Spontaneous Prematurity by Antibiotic Treatment (Josamycin) Josamycin, Placebo - Prematurity | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 3200 | 2008-07-01 | 2011-12-29 |
| Inhaled Nitric Oxide and Neuroprotection in Premature Infants inhaled nitric oxide, oxygen - Prematurity, Bronchopulmonary Dysplasia | Phase 2 / Phase 3 | Terminated | University of Chicago | 273 | 2008-05-01 | 2024-10-17 |
| Will CPAP Reduce Length Of Respiratory Support In Premature Infants? CPAP, Mechanical ventilation - Prematurity, Respiratory Distress Syndrome, Newborn | Phase 3 | Terminated | Children's & Women's Health Centre of British Columbia | 126 | 2007-09-01 | 2012-02-10 |
| Post-hospitalization Nursing Effectiveness (PHONE) Study Care coordination by telephone contacts with a nurse - Bronchopulmonary Dysplasia, Prematurity | Phase 3 | Completed | Wake Forest University | 150 | 1996-05-01 | 2017-11-06 |
| Indomethacin Germinal Matrix Hemorrhage/Intraventricular Hemorrhage (GMH/IVH) Prevention Trial indomethacin, placebo - Intraventricular Hemorrhage (IVH), Bleeding in the Brain | Phase 3 | Completed | Yale University | 630 | 1989-09-01 | 2013-03-28 |
Premature Birth (12) · Bronchopulmonary Dysplasia (5) · Fetal Growth Retardation (1) · Leukomalacia, Periventricular (1) · Lung Injury (1) · Neurodevelopmental Disorders (1) · Pre-Eclampsia (1) · Respiration Disorders (1) · Respiratory Aspiration (1) · Respiratory Distress Syndrome, Newborn (1) · Systemic carnitine deficiency (1)
Female Urogenital Diseases and Pregnancy Complications (12) · Obstetric Labor Complications (12) · Obstetric Labor, Premature (12) · Pregnancy Complications (12) · Urogenital Diseases (12) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (7) · Infant, Newborn, Diseases (6) · Infant, Premature, Diseases (6) · Lung Diseases (6) · Respiratory Tract Diseases (6) · Ventilator-Induced Lung Injury (5) · Lung Injury (4) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Brain Diseases (1)
Budesonide (1) · Carnitine (1) · Glucose (1) · Indomethacin (1) · Josamycin (1) · Oxygen (1) · Respiration, Artificial (1) · Sodium Chloride (1) · Standard of Care (1) · Sulfur Hexafluoride (1) · Vitamin A (1) · caffeine citrate (1) · contrast agent BR1 (1) · poractant alfa (1)
Assistance Publique - Hôpitaux de Paris (1) · Centro Hospitalar de Lisboa Central (1) · Children's & Women's Health Centre of British Columbia (1) · Erhan Calisici (1) · Hospital Clinic of Barcelona (1) · Ministry of Health, Saudi Arabia (1) · Montefiore Medical Center (1) · The University of Texas Health Science Center, Houston (1) · Turku University Hospital (1) · University of Chicago (1) · Wake Forest University (1) · Yale University (1)
United States (5) · Canada (1) · Finland (1) · France (1) · Portugal (1) · Saudi Arabia (1) · Turkey (Türkiye) (1)
Catarina Palma-dos-Reis, MD, MSc (1) · Erhan Calisici, MD (1) · Jussi Hirvonen (1) · Laura R. Ment, M.D. (1) · Mamta Fuloria, MD (1) · Marta Teresa-Palacio, MD (1) · Michael D. Schreiber, M.D. (1) · Nehad Nasef (1) · Rebecca L Sherlock, MD, FRCPC, PhD(c) (1) · Riitta Parkkola (1) · Thomas M O'Shea, MD, MPH (1) · Tiina Laurikainen (1) · Vilhelmiina Parikka (1)