60 completed, 17 recruiting, 15 not yet recruiting, 8 active not recruiting. 63 Not applicable, 19 Phase 4, 5 Phase 1, 5 Phase 3, 3 Phase 2.
Follow Postoperative Pain Management: new trials by email Literature Review of Postoperative Pain Management trials Research Report on Postoperative Pain Management
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Transversalis Fascia Plane Block Versus Surgical Wound Infiltration for Postoperative Analgesia in Open Inguinal Hernia Repair Ultrasound-Guided Transversalis Fascia Plane Block (TFPB), Surgical Wound Infiltration - Inguinal Hernia Unilateral, Postoperative Pain Management | Not applicable | Not yet recruiting | Ondokuz Mayıs University | 104 | 2027-01-01 | 2026-06-25 |
| Intraoperative Placement of Vancomycin-impregnated Calcium Sulfate Beads Conjugated With Analgesics to Improve Spine Surgery Outcomes Vancomycin (local, via calcium sulfate beads), Morphine (local, via calcium sulfate beads), Bupivacaine (local, via calcium sulfate beads) - Spine Surgery, Postoperative Pain Management | Phase 2 | Not yet recruiting | Ganesh M. Shankar | 100 | 2027-01-01 | 2026-04-16 |
| COMPARISON OF THE EFFECTS OF ERECTOR SPINAE PLANE (ESP) BLOCK AND QUADRO İLİAC PLANE (QIP) BLOCK ON POSTOPERATIVE OPIOID CONSUMPTION AND PAIN IN LUMBAR SPINAL SURGERY NRS Score, total tramadol consumption, Post Operative Pain Relievers - Postoperative Pain Management | Not applicable | Not yet recruiting | Aydin Adnan Menderes University | 80 | 2026-09-01 | 2026-10-01 |
| Methadone Pharmacokinetics in Cardiac Surgery Single dose of methadone, Split dose of methadone, Balanced split dose of methadone - Postoperative Pain Management | Phase 4 | Withdrawn | Wake Forest University Health Sciences | 2026-09-01 | 2026-08-17 | |
| Suzetrigine Versus Usual-care Opioids for Postop Pain in Sports Suzetrigine, Multimodal Pain Regimen - Postoperative Pain Management | Phase 4 | Not yet recruiting | University of California, Los Angeles | 140 | 2026-09-01 | 2026-07-31 |
| Dexmedetomidine-Enhanced PCIA After Lobectomy in Nicotine-Dependent Patients Oliceridine, Dexmedetomidine - Postoperative Pain Management | Phase 4 | Withdrawn | Shenyang Sixth People's Hospital | 2026-06-01 | 2026-04-13 | |
| Evaluating the Efficacy and Utility of the Automated Pupillometer in Pain Assessment and Opioid Administration Guidance During the Perioperative Period: A Randomized Controlled Trial Opioid Analgesic, automated pupillometry - Postoperative Pain, Postoperative Pain Management | Not applicable | Active not recruiting | University of Malaya | 68 | 2026-05-01 | 2026-05-29 |
| mTLIP vs QIPB for Postoperative Analgesia in Lumbar Microdiscectomy Surgery Modified Thoracolumbar Interfascial Plane Block (mTLIP), Quadro-Iliac Plane Block (QIPB) - Postoperative Pain Management | Not applicable | Recruiting | Bursa City Hospital | 80 | 2026-03-25 | 2026-03-27 |
| Minimum Effective Volume of Bupivacaine for Serratus Posterior Superior Intercostal Plane Block in Video-Assisted Thoracoscopic Surgery Ultrasound-Guided Serratus Posterior Superior Intercostal Plane Block - Postoperative Pain Management, Video-assisted Thoracoscopic Surgery (VATS) | Not applicable | Completed | Bursa City Hospital | 27 | 2026-03-15 | 2026-09-24 |
| Comprasion of SPSIP and Rhomboid Intercostal Plan Blocks on VATS RIB BLOCK, SPSIP block - Postoperative Pain Management | Not applicable | Recruiting | Cumhuriyet University | 40 | 2026-03-12 | 2026-06-03 |
| Effects of Ankle Block on Postoperative Analgesia in Diabetic and Non-Diabetic Patients Ultrasound-Guided Ankle Block - Diabetes Mellitus, Diabetic Neuropathy | Not applicable | Not yet recruiting | Fatih Sultan Mehmet Training and Research Hospital | 46 | 2026-03-01 | 2026-02-11 |
| Can Ultrasound-Guided Fascial Plane Blocks Reduce Postoperative Pulmonary Complications After Major Abdominal Surgery? Postoperative Pulmonary Complications (PPCs), Abdominal Surgeries | Recruiting | Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital | 500 | 2026-03-01 | 2026-04-30 | |
| ESPB vs SPSIP for Postoperative Analgesia After CABG Ultrasound-guided Erector Spinae Plane Block (ESPB), Ultrasound-guided Serratus Posterior Superior Intercostal Plane Block (SPSIPB) - Coronary Arterial Disease, Coronary Artery Bypass Grafting (CABG) Surgery | Not applicable | Recruiting | Kutahya Health Sciences University | 64 | 2026-03-01 | 2026-08-05 |
| Single- Versus Two-Level ESP Block for Analgesia After Lumbar Stabilization Surgery Single-Level Erector Spinae Plane Block, Two-Level Erector Spinae Plane Block - Postoperative Pain Management, Lumbar Spinal Fusion Surgery | Not applicable | Not yet recruiting | Ankara Etlik City Hospital | 60 | 2026-02-01 | 2026-01-23 |
| Assessment of Healthcare Professionals' Knowledge and Attitudes Toward Patient-Controlled Analgesia Patient-Controlled Analgesia Educational Program - Postoperative Pain Management | Not applicable | Completed | Kutahya Health Sciences University | 242 | 2026-01-23 | 2026-03-04 |
| SPSIP Block and Opioid Use After MICS Serratus Posterior Superior Intercostal Plane Block (SPSIPB), Sham Serratus Posterior Superior Intercostal Plane Block - Heart Valvular Disease, Minimally Invasive Cardiac Surgery | Not applicable | Completed | Ankara City Hospital Bilkent | 50 | 2026-01-22 | 2026-04-24 |
| Efficacy and Safety of Anrikefon for Postoperative Analgesia in Ophthalmic Surgery Anrikefon, Nalbuphine - Ophthalmic Surgery, Postoperative Pain Management | Phase 4 | Recruiting | Zhongshan Ophthalmic Center, Sun Yat-sen University | 204 | 2026-01-22 | 2026-04-01 |
| Effect of Intravenous Dexmedetomidine and Ketamine on Post-Operative Analgesia Dexmedetomidine, Ketamine, Saline (0.9% NaCl) - Postoperative Analgesia, Postoperative Pain Management | Phase 3 | Not yet recruiting | Zagazig University | 50 | 2026-01-20 | 2026-01-09 |
| Anatomical Measurements of Pudendal Nerve Block in Children Neurostimulation-Guided Pudendal Nerve Block - Postoperative Pain Management, Penile Surgery-Related Pain | Not yet recruiting | Istanbul University - Cerrahpasa | 50 | 2026-01-20 | 2026-01-16 | |
| Suprainguinal Fascia Iliaca Block With vs Without Dexmedetomidine Dexmedetomidine, Ropivacaine - Postoperative Pain Management | Phase 4 | Recruiting | Rhode Island Hospital | 120 | 2026-01-20 | 2026-03-25 |
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Pain, Postoperative (40) · Agnosia (23) · Pain (11) · Anxiety Disorders (4) · Hip Fractures (3) · Osteoarthritis, Knee (3) · Bites and Stings (2) · Postoperative Cognitive Complications (2) · Postoperative Complications (2) · Postoperative Nausea and Vomiting (2) · Acute Pain (1) · Behavior (1) · Breast Neoplasms (1) · Cholelithiasis (1) · Cognitive Dysfunction (1)
Pathological Conditions, Signs and Symptoms (65) · Signs and Symptoms (62) · Neurologic Manifestations (61) · Pathologic Processes (42) · Pain (40) · Postoperative Complications (40) · Nervous System Diseases (26) · Neurobehavioral Manifestations (24) · Perceptual Disorders (23) · Mental Disorders (8) · Musculoskeletal Diseases (5) · Wounds and Injuries (5) · Joint Diseases (4) · Male Urogenital Diseases (4) · Neoplasms (4)
Bupivacaine (10) · Dental Occlusion (7) · Morphine (7) · Dexmedetomidine (6) · Acetaminophen (5) · Ketamine (4) · Lidocaine (4) · Analgesia, Patient-Controlled (3) · Ibuprofen (3) · Magnesium Sulfate (3) · Parapsychology (3) · Saline Solution (3) · Single Person (3) · Sodium Chloride (3) · Analgesics, Opioid (2)
Pacira Pharmaceuticals, Inc (6) · Ataturk University (4) · Cumhuriyet University (4) · Ankara City Hospital Bilkent (3) · Gaziosmanpasa Research and Education Hospital (3) · Ain Shams University (2) · Ankara Ataturk Sanatorium Training and Research Hospital (2) · Assiut University (2) · Aydin Adnan Menderes University (2) · Başakşehir Çam & Sakura City Hospital (2) · Bezmialem Vakif University (2) · Bursa City Hospital (2) · Cairo University (2) · Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital (2) · Haisco Pharmaceutical Group Co., Ltd. (2)
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Ali Asgher, Mbbs, FCPS (2) · Igor Grachev, MD, PhD (2) · Ahmed A. Khalifa, MD (1) · Ana Maria Dumitriu, MD, PhD (1) · Arnulfo Calixto Flores, Prof MD, PhD (1) · Ashley B Bozzay, MD (1) · Aymen N Naguib, MD (1) · Ayse Cigdem Tutuncu, Professor Doctor (1)
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