6 completed, 4 recruiting, 4 terminated, 2 withdrawn. 19 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 19 | Completed 6, Recruiting 4, Terminated 4, Withdrawn 2, Active not recruiting 1, Not yet recruiting 1, Unknown 1 |
Follow Postoperative Pain Management: new trials by email Literature Review of Postoperative Pain Management trials Research Report on Postoperative Pain Management
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Methadone Pharmacokinetics in Cardiac Surgery Single dose of methadone, Split dose of methadone, Balanced split dose of methadone - Postoperative Pain Management | Phase 4 | Withdrawn | Wake Forest University Health Sciences | 2026-09-01 | 2026-08-17 | |
| Suzetrigine Versus Usual-care Opioids for Postop Pain in Sports Suzetrigine, Multimodal Pain Regimen - Postoperative Pain Management | Phase 4 | Not yet recruiting | University of California, Los Angeles | 140 | 2026-09-01 | 2026-07-31 |
| Dexmedetomidine-Enhanced PCIA After Lobectomy in Nicotine-Dependent Patients Oliceridine, Dexmedetomidine - Postoperative Pain Management | Phase 4 | Withdrawn | Shenyang Sixth People's Hospital | 2026-06-01 | 2026-04-13 | |
| Efficacy and Safety of Anrikefon for Postoperative Analgesia in Ophthalmic Surgery Anrikefon, Nalbuphine - Ophthalmic Surgery, Postoperative Pain Management | Phase 4 | Recruiting | Zhongshan Ophthalmic Center, Sun Yat-sen University | 204 | 2026-01-22 | 2026-04-01 |
| Suprainguinal Fascia Iliaca Block With vs Without Dexmedetomidine Dexmedetomidine, Ropivacaine - Postoperative Pain Management | Phase 4 | Recruiting | Rhode Island Hospital | 120 | 2026-01-20 | 2026-03-25 |
| Peritoneal Lavage Using Saline or Saline With Ondansetron for Pain Control After Laparoscopic Cholecystectomy Ondansetron Intraperitoneal Lavage, Saline Intraperitoneal Lavage - Postoperative Pain Management, Laparoscopic Cholecystectomy | Phase 4 | Active not recruiting | Instituto Mexicano del Seguro Social | 40 | 2025-12-01 | 2025-12-16 |
| Effect of Lidocaine-Dexmedetomidine on Pain, Inflammation, and Oxidative Stress After Bariatric Surgery. Intravenous Lidocaine infusion + Standard Anesthesia, Intravenous Dexmedetomidine infusion + Standard Anesthesia, Lidocaine + Dexmedetomidine Combination (LIDEX) + Standard Anesthesia - Morbid Obesity Requiring Bariatric Surgery, Postoperative Pain | Phase 4 | Recruiting | Instituto Mexicano del Seguro Social | 104 | 2025-10-06 | 2025-11-28 |
| Magnesium and Cramping Magnesium sulfate, Ketamine, Placebo - Uterine Cramps, Postoperative Pain Management | Phase 4 | Recruiting | Corewell Health East | 150 | 2025-07-29 | 2025-08-20 |
| Ultrasound-Guided Erector Spinae Plane Block Versus Intravenous Nalbuphine Erector Spinae (ESP) Block with Bupivacaine (Marcaine®) - Postoperative Pain Management | Phase 4 | Completed | Zagazig University | 102 | 2025-07-08 | 2026-02-05 |
| Low-Dose Lidocaine Infusion for Acute Pain Management Pilot Study Low-Dose Lidocaine - Postoperative Pain Management | Phase 4 | Completed | The Methodist Hospital Research Institute | 18 | 2021-07-02 | 2024-12-10 |
| Phase 4 Study in Adult Subjects Undergoing Posterior Lumbar Spine Surgeries EXPAREL and Bupivacaine, Standard of Care - Postoperative Pain Management | Phase 4 | Terminated | Pacira Pharmaceuticals, Inc | 65 | 2019-07-31 | 2021-11-09 |
| Phase 4, Controlled Study in Adult Subjects Undergoing Primary, 1-2 Level, Open Lumbar Spinal Fusion Surgery EXPAREL and bupivacaine HCl, Bupivacaine HCl - Postoperative Pain Management | Phase 4 | Terminated | Pacira Pharmaceuticals, Inc | 38 | 2017-02-21 | 2021-10-13 |
| Intravenous Lidocaine and Postoperative Pain Management Lidocaine, Saline Placebo - Postoperative Pain Management | Phase 4 | Unknown | Beijing Tongren Hospital | 80 | 2016-01-01 | 2016-12-19 |
| Early Postoperative Administration of Oxycodone +/- Naloxone and Duration of Epidural Analgesia oxycodone/naloxone, Oxycodone, Placebo - Postoperative Pain Management, Radical Cystectomy | Phase 4 | Completed | Insel Gruppe AG, University Hospital Bern | 90 | 2015-09-14 | 2017-03-07 |
| The Use of Intranasal Ketoralac for Pain Management (Sprix) Intranasal Ketoralac, Placebo - Postoperative Pain Management, Urolithiasis | Phase 4 | Terminated | Montefiore Medical Center | 50 | 2012-10-01 | 2020-02-13 |
| Low Pain Prediction in Cesarean Section Patients duramorph, placebo - Scheduled Cesarean Sections, Postoperative Pain Management | Phase 4 | Terminated | Wake Forest University Health Sciences | 13 | 2011-11-01 | 2018-09-10 |
| Pain Treatment After TKA With LIA and Intra-articular Continuous Infusion Pump Ropivacaine, Placebo - Postoperative Pain Management | Phase 4 | Completed | Region Skane | 200 | 2010-02-01 | 2014-11-26 |
| Perioperative Administration of Pregabalin in Patients Undergoing Arthroscopic Anterior Cruciate Ligament Reconstruction Pregabalin - Postoperative Pain Management | Phase 4 | Completed | Prince of Songkla University | 60 | 2009-08-01 | 2010-11-17 |
| Pregabalin, Celecoxib, Total Knee Arthroplasty and Intrathecal Morphine Pregabalin, Celecoxib, Pregabalin with celecoxib - Postoperative Pain Management, Total Knee Arthroplasty | Phase 4 | Completed | Chulalongkorn University | 100 | 2008-07-01 | 2011-08-04 |
Agnosia (4) · Pain (2) · Pain, Postoperative (2) · Kidney Calculi (1) · Postoperative Nausea and Vomiting (1) · Spasm (1) · Urolithiasis (1)
Neurologic Manifestations (7) · Pathological Conditions, Signs and Symptoms (7) · Signs and Symptoms (7) · Nervous System Diseases (5) · Neurobehavioral Manifestations (4) · Perceptual Disorders (4) · Pathologic Processes (3) · Postoperative Complications (3) · Pain (2) · Calculi (1) · Female Urogenital Diseases (1) · Female Urogenital Diseases and Pregnancy Complications (1) · Kidney Diseases (1) · Male Urogenital Diseases (1) · Nausea (1)
Bupivacaine (3) · Dexmedetomidine (3) · Lidocaine (3) · Pregabalin (2) · Ropivacaine (2) · Saline Solution (2) · Sodium Chloride (2) · ((3-methoxythiophen-2-yl)methyl)((2-(9-(pyridin-2-yl)-6-oxaspiro(4.5)decan-9-yl)ethyl))amine (1) · Celecoxib (1) · Dental Occlusion (1) · Fluocinonide (1) · Ketamine (1) · Ketorolac (1) · Magnesium Sulfate (1) · Methadone (1)
Instituto Mexicano del Seguro Social (2) · Pacira Pharmaceuticals, Inc (2) · Wake Forest University Health Sciences (2) · Beijing Tongren Hospital (1) · Chulalongkorn University (1) · Corewell Health East (1) · Insel Gruppe AG, University Hospital Bern (1) · Montefiore Medical Center (1) · Prince of Songkla University (1) · Region Skane (1) · Rhode Island Hospital (1) · Shenyang Sixth People's Hospital (1) · The Methodist Hospital Research Institute (1) · University of California, Los Angeles (1) · Zagazig University (1)
United States (7) · China (3) · Mexico (2) · Thailand (2) · Egypt (1) · Sweden (1) · Switzerland (1)
Arnulfo Calixto Flores, Prof MD, PhD (1) · Ettore Crimi, MD (1) · Fiona C Burkhard, MD (1) · Francisco Aguilar Espinosa, Dr. (1) · Gary Nevins, DC (1) · Gunnar Flivik, MD PhD (1) · Jessica Booth, MD (1) · Patrick Y Wuethrich, MD (1) · Ray Soto, MD (1) · Sasikaan Nimmaanrat, MD, MMed (1) · Singh Nair, MD (1) · Supranee Niruthisard, BSc, MD (1)
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