21 completed, 4 withdrawn, 2 terminated, 2 unknown. 14 Not applicable, 6 Phase 4, 4 Phase 3, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 14 | Completed 8, Withdrawn 4, Unknown 2 |
| Phase 4 | 6 | Completed 5, Not yet recruiting 1 |
| Phase 3 | 4 | Completed 3, Terminated 1 |
| Early Phase 1 | 1 | Terminated 1 |
Follow Postdural Puncture Headache: new trials by email Literature Review of Postdural Puncture Headache trials Research Report on Postdural Puncture Headache
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Coffee on Postdural Puncture Headache After Cesarean Section Coffee Consumption - Postdural Puncture Headache | Not applicable | Completed | Hacettepe University | 89 | 2026-02-20 | 2026-07-23 |
| Neutrophil to Lymphocyte Ratio and Postdural Headache PDPH - Preoperative Neutrophil-to-Lymphocyte Ratio (NLR), Postdural Puncture Headache | Recruiting | Istinye University | 821 | 2025-07-12 | 2025-07-24 | |
| A Prospective Cohort Study to Evaluate the Safety, Efficacy, and Usability of the EpiZact Device EpiZact-assisted epidural placement - Postdural Puncture Headache, Epidural Analgesia, Obstetric | Phase 4 | Not yet recruiting | Oregon Health and Science University | 100 | 2025-03-15 | 2025-02-14 |
| Plasma Rich Fibrin Epidural Injection by Racz Catheter Versus Epidural Blood Patch in Postdural Puncture Headache Epidural blood patch, Plasma rich fibrin epidural injection by Racz catheter - Plasma Rich Fibrin, Epidural | Not applicable | Completed | Tanta University | 60 | 2025-01-25 | 2025-12-09 |
| Plasma Rich Fibrin Epidural Injection by Racz Catheter in Postdural Puncture Headache Guided Optic Nerve Sheath Diameter Plasma rich fibrin epidural injection by Racz catheter - Plasma Rich Fibrin, Epidural | Not applicable | Completed | Tanta University | 60 | 2025-01-25 | 2025-12-02 |
| Pregabalin in Treatment of Postdural Puncture Headache Pregabalin 75mg, An epidural blood patch (EBP), conservative treatment. - Postdural Puncture Headache | Phase 3 | Completed | Al-Azhar University | 75 | 2024-02-28 | 2025-06-18 |
| Examination of Postdural Puncture Headache Frequency, Predisposing Factors and Treatment Postdural Puncture Headache | Completed | Mustafa Soner Ozcan | 400 | 2023-11-01 | 2024-09-19 | |
| Addition of Pyridostigmine to Conventional Management of Postdural Puncture Headache Pyridostigmine, Placebo - Postdural Puncture Headache | Phase 4 | Completed | Ain Shams University | 30 | 2023-07-25 | 2024-09-04 |
| Greater Occipital Nerve Block Value in Management of Postdural Puncture Headache Greater Occipital Nerve Block, Bilateral suboccipital intramuscular injection, Epidural Blood Patch - Postdural Puncture Headache | Not applicable | Completed | Benha University | 152 | 2023-03-02 | 2024-04-24 |
| The Relationship Between Post Dural Puncture Headache and Joint Laxity examination - Postdural Puncture Headache | Not applicable | Unknown | Adiyaman University Research Hospital | 80 | 2022-02-15 | 2022-02-10 |
| Postdural Punction Headache After Ceserian Section Patients who underwent cesarean section under spinal anesthesia with 25 gauge spinal needle, Patients who underwent cesarean section under spinal anesthesia with 26 gauge spinal needle, Patients who underwent cesarean section operation under spinal anesthesia with 27 gauge spinal needle - Postdural Puncture Headache, Regional Anesthesia Morbidity | Not applicable | Completed | Bakirkoy Dr. Sadi Konuk Research and Training Hospital | 750 | 2022-02-01 | 2023-03-21 |
| Effect of Anodal Transcranial Direct Current Stimulation on Postdural Puncture Headache active in therapeutic tDCS (Th-tDCS): anodal transcranial Direct Current Stimulation (a-tDCS), sham in therapeutic tDCS (Th-tDCS): anodal transcranial Direct Current Stimulation (a-tDCS), active in preventive tDCS (Pr-tDCS): anodal transcranial Direct Current Stimulation (a-tDCS) - Postdural Puncture Headache, Lumbar Puncture | Not applicable | Completed | Neuromed IRCCS | 97 | 2022-01-11 | 2025-04-02 |
| Spenopalatine Ganglion Block for Treatment of Post-dural Puncture Headaches 2% lidocaine, Placebo - Postdural Puncture Headache | Not applicable | Withdrawn | McMaster University | 2021-12-01 | 2026-07-07 | |
| Nebulized Dexmedetomidine Versus Neostigmine/Atropine in Postdural Puncture Headache Dexmedetomidine, Neostigmine/atropine, Saline placebo - Postdural Puncture Headache | Phase 3 | Completed | Assiut University | 90 | 2021-06-01 | 2021-09-08 |
| Effect of Intravenous Versus Intrathecal Dexamethazone on Postdural Puncture Headache Dexamethasone intravenous, Dexamethasone intrathecal - Postdural Puncture Headache | Not applicable | Unknown | Ain Shams University | 220 | 2021-01-20 | 2021-01-22 |
| Changes in Cerebral Blood Flow (CBF) in Prone and Sitting Position Before and After GSP-block and Before and After Epidural Blood-patch: A Substudy of NCT03652714 Ganglion sphenopalatine block with local anesthetic administered on study GSPB-2018, Ganglion sphenopalatine block with placebo administered on study GSPB-2018 - Postdural Puncture Headache, Sphenopalatine Ganglion Block | Not applicable | Withdrawn | University Hospital Bispebjerg and Frederiksberg | 2020-05-01 | 2020-11-20 | |
| Sphenopalatine Ganglion Nerve Block for Postdural Puncture Headache in Obstetrics Lidocaine 4%, Placebo - Postdural Puncture Headache, Cerebrospinal Fluid Leak | Phase 4 | Completed | Hadassah Medical Organization | 40 | 2020-01-08 | 2026-10-08 |
| Sphenopalatine Ganglion Block for Postdural Puncture Headache Conservative Treatment for Postdural Puncture Headache - Postdural Puncture Headache | Completed | Sakarya University | 110 | 2019-12-01 | 2021-05-19 | |
| Sphenopalatine Ganglion Block for Postdural Puncture Headache in the Emergency Department Sphenopalatine Ganglion Block, Placebo - Postdural Puncture Headache | Not applicable | Withdrawn | University of Arkansas | 2019-01-01 | 2019-09-25 | |
| Ondansetron and Dexamethasone for Prevention of PDPH, Nausea, and Vomiting Ondansetron 8mg, Dexamethasone, Saline - Postdural Puncture Headache, Postoperative Nausea and Vomiting | Phase 4 | Completed | Minia University | 150 | 2018-10-01 | 2025-07-18 |
Showing 20 of 31. Sign in to see all of them.
Post-Dural Puncture Headache (31) · Headache (3) · Cerebrospinal Fluid Leak (2) · Nausea (1) · Postoperative Nausea and Vomiting (1) · Vomiting (1)
Brain Diseases (31) · Central Nervous System Diseases (31) · Headache Disorders (31) · Headache Disorders, Secondary (31) · Nervous System Diseases (31) · Pathological Conditions, Signs and Symptoms (4) · Signs and Symptoms (4) · Neurologic Manifestations (3) · Pain (3) · Craniocerebral Trauma (2) · Trauma, Nervous System (2) · Wounds and Injuries (2) · Pathologic Processes (1) · Postoperative Complications (1) · Signs and Symptoms, Digestive (1)
Saline Solution (5) · Sphenopalatine Ganglion Block (5) · Blood Patch, Epidural (4) · Sodium Chloride (4) · Lidocaine (3) · Bupivacaine (2) · Conservative Treatment (2) · Morphine (2) · Anesthetics, Local (1) · Atropine (1) · Cosyntropin (1) · Dexamethasone (1) · Dexmedetomidine (1) · High-Energy Shock Waves (1) · Injections (1)
Ain Shams University (2) · Tanta University (2) · University Hospital Bispebjerg and Frederiksberg (2) · University of Arkansas (2) · Adiyaman University Research Hospital (1) · Al-Azhar University (1) · Assiut University (1) · Bakirkoy Dr. Sadi Konuk Research and Training Hospital (1) · Benha University (1) · Columbia University (1) · Diskapi Yildirim Beyazit Education and Research Hospital (1) · Hacettepe University (1) · Hadassah Medical Organization (1) · Istinye University (1) · McMaster University (1)
Egypt (9) · Turkey (Türkiye) (7) · United States (7) · Canada (2) · Denmark (2) · France (1) · Israel (1) · Italy (1)
Brandon M Togioka, MD (1) · Burak Kaya, MD (1) · Carly Eastin, MD (1) · Duygu Akyol, M.D (1) · Feyce Peralta, MD (1) · Jose CA Carvalho, MD PhD (1) · Mustafa Soner Mustafa Soner (1) · Omar Soliman (1) · Peter H Pan, MD, MSEE (1) · Richard Smiley, MD, PhD (1)
PMID 30070060, PMID 31073654, PMID 32303377, PMID 33993346, PMID 34141426, PMID 36808350, PMID 38850761, PMID 40073366, PMID 40261600