188 completed, 52 unknown, 45 recruiting, 25 not yet recruiting. 201 Not applicable, 30 Phase 2, 28 Phase 4, 18 Phase 3, 14 Phase 1.
Follow Headache Disorders, Secondary: new trials by email Literature Review of Headache Disorders, Secondary trials Research Report on Headache Disorders, Secondary
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Behavior Therapy vs Education for Persistent Headache After Mild TBI Headache reprocessing, Headache education - Post-Traumatic Headache | Not applicable | Not yet recruiting | VA Office of Research and Development | 60 | 2027-10-01 | 2025-12-26 |
| Comparing Spinal, Epidural, and Dural Puncture Epidural Anesthesia for Cesarean Delivery: Hemodynamics and Block Quality Spinal Anesthesia, Epidural Anesthesia, Dural Puncture Epidural Anesthesia - Hypotension After Neuraxial Anesthesia, Cesarean Section | Not applicable | Not yet recruiting | Bursa Yuksek Ihtisas Training and Research Hospital | 120 | 2026-12-01 | 2026-10-20 |
| Osteopathic Care Combined With Physiotherapy and Pain Education for Cervicogenic Headache Osteopathic Care, Physiotherapy, Sham (No Treatment) - Cervicogenic Headache | Not applicable | Not yet recruiting | Centro Universitário Augusto Motta | 120 | 2026-11-01 | 2026-08-31 |
| Mindful RAVANS Study Cala-RAVANS (Model CR-2), Sham - mTBI - Mild Traumatic Brain Injury, Posttraumatic Stress Disorder | Not applicable | Not yet recruiting | Spaulding Rehabilitation Hospital | 20 | 2026-11-01 | 2026-10-14 |
| Eary Infusion of Eptinezumab for TreatmEnt of ACute Post-Traumatic Headaches (ELITE-ACT) Eptinezumab, Placebo - Post Traumatic Headache | Phase 3 | Not yet recruiting | Sunnybrook Health Sciences Centre | 80 | 2026-09-30 | 2026-08-13 |
| Mulligan Technique Versus Proprioceptive Training in Cervicogenic Headache Mulligan Technique, Proprioceptive Training, Conventional physical therapy program - Cervicogenic Headache | Not applicable | Not yet recruiting | Cairo University | 48 | 2026-09-24 | 2026-09-22 |
| Effect of Intravenous Oxytocin on Post Dural Puncture Headache After Caesarean Sections oxytocin, Normal Saline - Post Dural Puncture Headache | Phase 4 | Not yet recruiting | Assiut University | 100 | 2026-09-01 | 2026-10-02 |
| Greater Occipital Nerve Blockade in Veterans With Post-concussion Headache: Sub-study 2 Bupivacaine bilateral greater occipital nerve block - Post-Traumatic Headache | Phase 2 | Recruiting | Yale University | 36 | 2026-09-01 | 2026-09-08 |
| Manual Therapy vs. Multicomponent Exercise in Cervicogenic Headache Manual Therapy Protocol, Multicomponent Exercise Program - Cervicogenic Headache, Proprioceptive Disorders | Not applicable | Not yet recruiting | Pamukkale University | 32 | 2026-09-01 | 2026-08-24 |
| CORRELATION BETWEEN FORWARD HEAD POSTURE, CERVICAL MUSCLES ENDURANCE, AND PROPRIOCEPTIVE FUCTIONS IN CERVICOGENIC HEADACHE AMONG LATE ADOLESCENT STUDENTS. Cervicogenic Headache | Not yet recruiting | Delta University for Science and Technology | 100 | 2026-08-10 | 2026-08-13 | |
| Effects of Graston Versus Myofascial Release Technique in Patients With Cervicogenic Headache Graston technique, Myofascial Release Therapy - Cervicogenic Headache | Not applicable | Not yet recruiting | Riphah International University | 48 | 2026-07-01 | 2026-07-24 |
| Predictive Value of ONSD and NIRS for PDPH Post-Dural Puncture Headache, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use | Recruiting | Ordu University | 44 | 2026-06-19 | 2026-07-27 | |
| Greater Occipital Nerve Block for Migraine With Medication Overuse Headache Lidocaine 2% and Methylprednisolone 80 mg, Placebo - Migraine Disorders, Medication Overuse Headache | Not applicable | Recruiting | Mahidol University | 130 | 2026-05-12 | 2026-10-08 |
| Comparison of Post-Dural Puncture Headache After Spinal Anesthesia Using Median Versus Paramedian Approach Spinal anesthesia using median approach (midline), Spinal anesthesia using paramedian approach - Post-Dural Puncture Headache, Headache After Spinal Puncture | Not applicable | Not yet recruiting | Mayo Hospital Lahore | 142 | 2026-05-01 | 2026-02-27 |
| Osteopathic Manipulative Treatment vs Physiotherapy in Cervicocranial Dysfunction Participants in this group will receive osteopathic manipulative treatment (OMT) targeting cervicocr, conventional physiotherapy - Cervicogenic Headache, Dizziness | Not applicable | Recruiting | Burim Peli | 50 | 2026-05-01 | 2026-04-29 |
| Ultrasound-assisted vs Palpation-guided Lumbar Punctures Ultrasound-Assisted Lumbar Puncture, Standard Palpation-Guided Lumbar Puncture - Lumbar Puncture | Not applicable | Enrolling by invitation | The Cooper Health System | 132 | 2026-04-25 | 2026-09-17 |
| Physical Profile of Cervicogenic Headache: Comparison With Neck Pain and Healthy Controls Cervicogenic Headache, Chronic Neck Pain | Recruiting | Istanbul Medipol University Hospital | 135 | 2026-04-21 | 2026-08-21 | |
| The Role Of Fascia And Breathing Exercises In The Treatment Of Cervicogenic Headache Thoracolumbar Fascia Exercise, Breathing Exercise, Conventional treatment - Cervicogenic Headache | Not applicable | Active not recruiting | Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital | 72 | 2026-04-20 | 2026-09-22 |
| The Effect of Magnesium on Post-spinal Headaches Magnesium - Post-spinal Headache | Active not recruiting | Haseki Training and Research Hospital | 300 | 2026-04-01 | 2026-07-07 | |
| Optic Nerve Sheath Diameter for Predicting Post-Dural Puncture Headache in Cesarean Section Patients Optic Nerve Sheath Diameter Measurement - Post Dural Puncture Headache | Not yet recruiting | Kocaeli University | 220 | 2026-03-20 | 2026-03-27 |
Showing 20 of 357. Sign in to see all of them.
Post-Traumatic Headache (186) · Post-Dural Puncture Headache (119) · Headache (63) · Migraine Disorders (32) · Neck Pain (24) · Headache Disorders (20) · Pain (19) · Brain Concussion (16) · Brain Injuries, Traumatic (11) · Post-Concussion Syndrome (10) · Tension-Type Headache (10) · Motor Activity (8) · Agnosia (6) · Migraine without Aura (6)
Brain Diseases (355) · Central Nervous System Diseases (354) · Nervous System Diseases (353) · Headache Disorders (337) · Pathological Conditions, Signs and Symptoms (111) · Signs and Symptoms (109) · Neurologic Manifestations (106) · Pain (75) · Wounds and Injuries (35) · Trauma, Nervous System (33) · Headache Disorders, Primary (32) · Craniocerebral Trauma (28) · Brain Injuries (22) · Wounds, Nonpenetrating (20)
Sphenopalatine Ganglion Block (16) · Sodium Chloride (14) · Saline Solution (11) · Lidocaine (10) · Blood Patch, Epidural (9) · Dry Needling (9) · Exercise (9) · Myofascial Release Therapy (7) · Neostigmine (6) · erenumab (6) · Acetaminophen (5) · Bupivacaine (5) · Dexamethasone (5) · Sumatriptan (5) · Therapeutics (5)
Riphah International University (19) · Danish Headache Center (16) · Cairo University (15) · Foundation University Islamabad (6) · Mayo Clinic (6) · Ain Shams University (5) · Assiut University (5) · Tanta University (5) · University of Calgary (5) · University of Florence (5) · University of Washington (5) · Zagazig University (5) · Ankara City Hospital Bilkent (4) · St. Olavs Hospital (4) · Al-Azhar University (3)
United States (87) · Egypt (44) · Turkey (Türkiye) (39) · Pakistan (36) · Denmark (22) · Canada (15) · Norway (14) · China (11) · France (11) · Italy (11) · Spain (8) · Brazil (5) · Israel (5) · Sweden (5) · Australia (4)
Hakan Ashina, MD (3) · Jeanne M Hoffman, PhD (3) · Ahmed M Shaat, MD (2) · Kaiming Liu, Doctor (2) · Milena Zirovich, MD (2) · Muhammad Affan Iqbal, PhD* (2) · Roger K Cady, MD (2) · Shereen E Abd Ellatif, MD (2) · Todd Schwedt (2) · Abd El-Aleem A Attia, professor (1) · Abdelgalil Allam Abdelgalil, PhD (1) · Adrien Guyot (1)
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2018 (2), 1IK2RX001136-01A2 (1), 1UL1TR003098 (1), 2004 (1), 2015 (1), 2025 (1), I21RX003612 (1), KL2TR002317-03S1 (1), R01AT007137 (1), R61NS113315 (1), UL1TR001073 (1)