5 completed, 1 not yet recruiting. 6 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 6 | Completed 5, Not yet recruiting 1 |
Follow Postdural Puncture Headache: new trials by email Literature Review of Postdural Puncture Headache trials Research Report on Postdural Puncture Headache
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Prospective Cohort Study to Evaluate the Safety, Efficacy, and Usability of the EpiZact Device EpiZact-assisted epidural placement - Postdural Puncture Headache, Epidural Analgesia, Obstetric | Phase 4 | Not yet recruiting | Oregon Health and Science University | 100 | 2025-03-15 | 2025-02-14 |
| Addition of Pyridostigmine to Conventional Management of Postdural Puncture Headache Pyridostigmine, Placebo - Postdural Puncture Headache | Phase 4 | Completed | Ain Shams University | 30 | 2023-07-25 | 2024-09-04 |
| Sphenopalatine Ganglion Nerve Block for Postdural Puncture Headache in Obstetrics Lidocaine 4%, Placebo - Postdural Puncture Headache, Cerebrospinal Fluid Leak | Phase 4 | Completed | Hadassah Medical Organization | 40 | 2020-01-08 | 2026-10-08 |
| Ondansetron and Dexamethasone for Prevention of PDPH, Nausea, and Vomiting Ondansetron 8mg, Dexamethasone, Saline - Postdural Puncture Headache, Postoperative Nausea and Vomiting | Phase 4 | Completed | Minia University | 150 | 2018-10-01 | 2025-07-18 |
| 2 Dose Neuraxial Morphine for Prevention of PDPH Morphine, Sterile normal saline - Postdural Puncture Headache | Phase 4 | Completed | Columbia University | 44 | 2015-09-01 | 2025-02-05 |
| Cosyntropin Versus Epidural Blood Patch (EBP) for Treatment of Treatment of Post Dural Puncture Headache Cosyntropin, Epidural Blood Patch - Postdural Puncture Headache | Phase 4 | Completed | United States Naval Medical Center, San Diego | 29 | 2010-08-01 | 2016-11-01 |
Post-Dural Puncture Headache (6) · Cerebrospinal Fluid Leak (1) · Headache (1) · Nausea (1) · Postoperative Nausea and Vomiting (1) · Vomiting (1)
Brain Diseases (6) · Central Nervous System Diseases (6) · Headache Disorders (6) · Headache Disorders, Secondary (6) · Nervous System Diseases (6) · Pathological Conditions, Signs and Symptoms (2) · Signs and Symptoms (2) · Craniocerebral Trauma (1) · Neurologic Manifestations (1) · Pain (1) · Pathologic Processes (1) · Postoperative Complications (1) · Signs and Symptoms, Digestive (1) · Trauma, Nervous System (1) · Wounds and Injuries (1)
Sodium Chloride (3) · Blood Patch, Epidural (1) · Cosyntropin (1) · Dexamethasone (1) · Lidocaine (1) · Morphine (1) · Ondansetron (1) · Pyridostigmine Bromide (1) · Saline Solution (1)
Ain Shams University (1) · Columbia University (1) · Hadassah Medical Organization (1) · Minia University (1) · Oregon Health and Science University (1) · United States Naval Medical Center, San Diego (1)
Egypt (2) · United States (2) · Israel (1)
Brandon M Togioka, MD (1) · Richard Smiley, MD, PhD (1) · Steven Hanling, MD (1) · Yehuda Ginosar, MBBS (1)