6 completed, 4 terminated, 1 enrolling by invitation, 1 recruiting. 6 Not applicable, 3 Phase 3, 2 Phase 4, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 4, Terminated 2 |
| Phase 3 | 3 | Recruiting 1, Terminated 1, Withdrawn 1 |
| Phase 4 | 2 | Completed 1, Terminated 1 |
| Phase 2 | 1 | Withdrawn 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy of Sphenopalatine Block Compared to Blood Patch in the Management of Post-dural Puncture Headaches Sphenopalatine Ganglion Block, Blood patch - PDPH, Post Dural Puncture Headache | Phase 3 | Recruiting | University Hospital, Clermont-Ferrand | 80 | 2026-02-19 | 2026-02-27 |
| Plasma Rich Fibrin Epidural Injection by Racz Catheter Versus Epidural Blood Patch in Postdural Puncture Headache Epidural blood patch, Plasma rich fibrin epidural injection by Racz catheter - Plasma Rich Fibrin, Epidural | Not applicable | Completed | Tanta University | 60 | 2025-01-25 | 2025-12-09 |
| Establishment of a Predictive Model for Post-dural Puncture Headache Supplement fluids - Spinal and Epidural Anaesthesia-Induced Headache During Pregnancy | Enrolling by invitation | Yilin Zhao | 480 | 2025-01-20 | 2025-01-30 | |
| Greater Occipital Nerve Block Value in Management of Postdural Puncture Headache Greater Occipital Nerve Block, Bilateral suboccipital intramuscular injection, Epidural Blood Patch - Postdural Puncture Headache | Not applicable | Completed | Benha University | 152 | 2023-03-02 | 2024-04-24 |
| Chronic Headache and Chronic Backache Following Unintentional Dural Puncture at Delivery Room. Epidural Blood patch. - Parturient Who Underwent Epidural Anesthesia During Which an Unintentional Dural Punctur Occurred, Parturient Who Develop a Postdural Puncture Headache | Completed | Shaare Zedek Medical Center | 389 | 2019-05-01 | 2020-08-14 | |
| Sphenopalatine Block or Epidural Bloodpatch for Post Dural Puncture Headache: Randomized Controlled Trial Sphenopalatine ganglion block, Epidural blood patch - Post-Dural Puncture Headache | Not applicable | Terminated | Brasilia University Hospital | 19 | 2016-12-01 | 2020-02-28 |
| Treatment of Post-dural Puncture Headache in Postpartum Patients: Sphenopalatine Ganglion Block to Epidural Blood Patch. Sphenopalatine ganglion Block, Epidural blood patch - Headache | Phase 4 | Terminated | University of Colorado, Denver | 4 | 2016-11-01 | 2020-01-23 |
| Therapeutic Epidural Patch Versus Pain Block in the Midface for Headache Epidural Blood Patch, Sphenopalatine Ganglion Block - Postdural Puncture Headache | Phase 3 | Terminated | Rutgers, The State University of New Jersey | 8 | 2016-09-01 | 2023-06-22 |
| Maintaining a Prone Position After Use of an Epidural Blood Patch for the Treatment of Post-dural Puncture Headache Prone position for 1 hour after blood patch, Blood patch - Post-Dural Puncture Headache | Not applicable | Terminated | Centre Hospitalier Universitaire de Nīmes | 3 | 2015-12-01 | 2017-02-01 |
| Spontaneous Intracranial Hypotension Treatment "SIHT" 24 hours Trendelenburg position, 24 hours bed rest, EBP - Spontaneous Intracranial Hypotension | Not applicable | Completed | Assistance Publique - Hôpitaux de Paris | 64 | 2014-12-01 | 2022-04-21 |
| HES Patch Versus Blood Patch injection of HES " Voluven® ", blood patch - Intracranial Hypotension | Not applicable | Completed | University Hospital, Strasbourg, France | 20 | 2013-06-01 | 2019-08-20 |
| Cosyntropin Versus Epidural Blood Patch (EBP) for Treatment of Treatment of Post Dural Puncture Headache Cosyntropin, Epidural Blood Patch - Postdural Puncture Headache | Phase 4 | Completed | United States Naval Medical Center, San Diego | 29 | 2010-08-01 | 2016-11-01 |
| Epidural Blood Patch on the Resolution of Postdural Puncture Headache (PDPH) Epidural Blood Patch - Post-Lumbar Puncture Headache | Phase 2 / Phase 3 | Withdrawn | The University of Texas Health Science Center, Houston | 2006-09-01 | 2020-11-05 |
Post-Dural Puncture Headache (9) · Headache (2) · Intracranial Hypotension (2) · Headache Disorders (1)
Assistance Publique - Hôpitaux de Paris (1) · Benha University (1) · Brasilia University Hospital (1) · Centre Hospitalier Universitaire de Nīmes (1) · Rutgers, The State University of New Jersey (1) · Shaare Zedek Medical Center (1) · Tanta University (1) · The University of Texas Health Science Center, Houston (1) · United States Naval Medical Center, San Diego (1) · University Hospital, Clermont-Ferrand (1) · University Hospital, Strasbourg, France (1) · University of Colorado, Denver (1) · Yilin Zhao (1)
France (4) · United States (3) · Egypt (2) · Brazil (1) · China (1) · Israel (1)
Adrien Guyot (1) · Cristina Wood, M.D. (1) · Gabriel MN Guimaraes, MsC, MD (1) · Guy Aya, MD (1) · Nicholas C.K. Lam, M.D. (1) · Steven Hanling, MD (1) · William Grubb, DDS, MD (1) · Yilin Zhao (1)
PMID 11412202, PMID 11506102, PMID 15321154, PMID 15321604, PMID 16407806, PMID 21320088, PMID 23219220, PMID 25483233, PMID 27378709, PMID 28416992, PMID 29368949, PMID 30063655, PMID 30636799, PMID 32303377, PMID 35358942, PMID 36050945, PMID 36337388, PMID 37422191, PMID 37581893, PMID 8249562, PMID 8490410, PMID 9211475, PMID 9512843
2025 (1)