14 completed, 6 unknown, 4 recruiting, 4 terminated. 22 Not applicable, 5 Phase 3, 3 Phase 4, 2 Phase 2, 1 Early Phase 1.
Follow Sphenopalatine Ganglion Block: new trials by email Literature Review of Sphenopalatine Ganglion Block trials Research Report on Sphenopalatine Ganglion Block
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Sphenopalatine Ganglion Block for Pain Relief After Pediatric Adenotonsillectomy Sphenopalatine ganglion block (Ropivacaine), Sham sphenopalatine ganglion block (Saline) - Postoperative Pain, Tonsillectomy | Phase 4 | Not yet recruiting | Vinícius C Quintão, MD, MSc, PhD | 145 | 2026-09-15 | 2026-08-28 |
| Improving Postoperative Analgesia After Functional Endoscopic Surgery Sphenopalatine ganglion block (SPGB) with Bupivacaine and Dexmedetomidine - Pain Management After Functional Endoscopic Sinuscopy | Phase 2 / Phase 3 | Not yet recruiting | South Egypt Cancer Institute | 20 | 2026-04-15 | 2026-04-29 |
| Efficacy of Sphenopalatine Block Compared to Blood Patch in the Management of Post-dural Puncture Headaches Sphenopalatine Ganglion Block, Blood patch - PDPH, Post Dural Puncture Headache | Phase 3 | Recruiting | University Hospital, Clermont-Ferrand | 80 | 2026-02-19 | 2026-02-27 |
| Prilocaine for Sphenopalatine Ganglion Block in Endoscopic Hypophysectomy Sphenopalatine Ganglion Block using 2% lidocaine, Sphenopalatine Ganglion Block - Blood Pressure Control | Not applicable | Recruiting | Kasr El Aini Hospital | 54 | 2025-12-01 | 2025-12-05 |
| The Effect of Sphenopalatine Ganglion Block on Headache and Vasalgia Sphenopalatine Ganglion Block, Sham Block - Vasalgia, Headache | Not applicable | Completed | University Hospital Bispebjerg and Frederiksberg | 42 | 2025-06-18 | 2025-07-11 |
| Sphenopalatine Block Versus BOTOX in Management of Chronic Migraine Sphenopalatine block, Botulinum Toxin Type A - Sphenopalatine Block, BOTOX | Not applicable | Recruiting | Cairo University | 64 | 2025-05-15 | 2025-05-16 |
| Effectiveness of Bilateral Endoscopic Sphenopalatine Ganglion Block on Postoperative Pain After Septoplasty Sphenopalatine Ganglion Block - Postoperative Pain | Not applicable | Not yet recruiting | Umraniye Education and Research Hospital | 50 | 2024-11-01 | 2024-11-19 |
| Sphenopalatine Block vs Dexmedetomidine Infusion in Trans Nasal Endoscopic Pituitary Surgery Sphenopalatine Ganglion Block, Dexmedetomidine, General Anesthesia (control group) - Sphenopalatine Ganglion Nerve Block, Transnasal Endoscopic Pitutary Surgery | Not applicable | Active not recruiting | Zagazig University | 69 | 2024-10-01 | 2026-01-02 |
| Sphenopalatine Ganglion Block in Bimaxillary Orthognathic Surgery Sphenopalatine Ganglion Block, Sham Block - Bimaxillar Surgery, Sphenopalatine Ganglion Block | Not applicable | Recruiting | Bezmialem Vakif University | 50 | 2024-06-25 | 2025-04-18 |
| Sphenopalatine Ganglion Block for Post-Dural Puncture Headache Sphenopalatine ganglion block, Conservative management - Post-Dural Puncture Headache, Headache | Not applicable | Completed | ISSSTE Hospital Regional "Gral. Ignacio Zaragoza" | 26 | 2024-05-29 | 2026-05-15 |
| Sphenopalatine Ganglion Block in Septorhinoplasty Sphenopalatine Ganglion Block - Pain, Postoperative, Rhinoplasty | Completed | Istanbul Medeniyet University | 50 | 2023-06-07 | 2023-12-06 | |
| A Study of SPG Block for Opioid Withdrawal sphenopalatine ganglion block - Opioid Use Disorder | Not applicable | Completed | New York State Psychiatric Institute | 3 | 2023-02-03 | 2025-10-30 |
| Lidocaine Versus Bupivacaine for Sphenopalatine Ganglion Block Sphenopalatine Ganglion Block (SPGB) - Septum; Deviation, Congenital | Not applicable | Completed | Huda Fahmy Mahmoud, PhD | 60 | 2022-03-01 | 2022-09-07 |
| Assessment of the Efficacy of the Transnasal Sphenopalatine Ganglion Block in the Treatment of Chronic Daily Headache in Children and Adolescents. Sphenopalatine ganglion block with 0.5% bupivacaine, Sphenopalatine ganglion block with saline - Chronic Daily Headache, Post-Traumatic Headache | Not applicable | Unknown | Pablo Ingelmo | 120 | 2022-02-05 | 2022-01-28 |
| The Effect of Ganglion Sphenopalatine Block (GSP-block) Follow-Up Ganglion Sphenopalatine Block - Post-Dural Puncture Headache, Ganglion Sphenopalatine Block | Completed | University Hospital Bispebjerg and Frederiksberg | 38 | 2021-11-26 | 2022-04-29 | |
| Sphenopalatine Ganglion Block for Management of Post- Dural Puncture Headache in Obstetric Patients Sphenopalatine ganglion block, paracetamol - Post-Dural Puncture Headache | Not applicable | Completed | Ain Shams University | 40 | 2021-03-15 | 2022-02-16 |
| Sphenopalatine Ganglion Block and Pain Management in Neurosurgery Sphenopalatine ganglion block, Standard Preparation - Post Operative Pain, Craniofacial Pain | Not applicable | Unknown | University Hospital of Ferrara | 84 | 2021-02-01 | 2021-11-29 |
| The Effect of Ganglion Sphenopalatine Block Versus Placebo on Persistent Headache Following COVID-19 Infection Sphenopalatine Ganglion Block with Local Anesthetic, Sphenopalatine Ganglion Block with Placebo (Isotone NaCl), "Sham"-block with Placebo (Isotone NaCl) - Headache, Covid19 | Phase 3 | Terminated | University Hospital Bispebjerg and Frederiksberg | 18 | 2021-01-12 | 2022-06-10 |
| Transnasal Sphenopalatine Ganglia Block for Management of Chronic Migraines in Pediatric Patients Headache Journal, Sphenopalatine Block, Tx360 - Migraine in Children, Pain, Neuropathic | Phase 2 | Withdrawn | Washington University School of Medicine | 2021-01-02 | 2021-02-10 | |
| Sphenopalatine Ganglion Block for Post-Dural Puncture Headache in Orthopedic Patients Sphenopalatine Ganglion Block, Medical Treatment - Sphenopalatine Ganglion Block, Adrenaline | Phase 4 | Unknown | Tanta University | 60 | 2020-12-10 | 2020-12-08 |
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Post-Dural Puncture Headache (15) · Headache (5) · Pain, Postoperative (5) · Headache Disorders (2) · COVID-19 (1) · Central Nervous System Diseases (1) · Edema (1) · Facial Pain (1) · Neuralgia (1) · Opioid-Related Disorders (1) · Pain (1) · Post-Traumatic Headache (1) · Stress Disorders, Post-Traumatic (1)
University Hospital Bispebjerg and Frederiksberg (5) · New York State Psychiatric Institute (2) · Zagazig University (2) · Ain Shams University (1) · Assiut University (1) · Bahaa Mohammed Refaie (1) · Bezmialem Vakif University (1) · Brasilia University Hospital (1) · Brigham and Women's Hospital (1) · Cairo University (1) · Derince Training and Research Hospital (1) · Huda Fahmy Mahmoud, PhD (1) · ISSSTE Hospital Regional "Gral. Ignacio Zaragoza" (1) · Istanbul Medeniyet University (1) · Kasr El Aini Hospital (1)
Egypt (9) · United States (6) · Denmark (5) · Turkey (Türkiye) (4) · Brazil (3) · Canada (1) · France (1) · Italy (1) · Mexico (1)
Adrien Guyot (1) · Burak Kaya, MD (1) · Carly Eastin, MD (1) · Christian S Meyhoff, PhD (1) · Cristina Wood, M.D. (1) · Gabriel MN Guimaraes, MsC, MD (1) · Hala Abdel-Ghaffar, MD (1) · Harun Uysal, Associate Professor (1) · Hermann S Fernandes, PhD (1) · Ismar S Cavalcanti, MD. (1) · Jacob AuBuchon, MD (1)
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