4 completed, 3 recruiting, 1 unknown, 1 withdrawn. 9 Phase 2, 2 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Completed 4, Recruiting 3, Unknown 1, Withdrawn 1 |
| Phase 1 | 2 | Recruiting 1, Unknown 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow Pain, Neuropathic: new trials by email Literature Review of Pain, Neuropathic trials Research Report on Pain, Neuropathic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Analgesic Efficacy and Safety of Topical VMD-3866 Gel in Management of Pain Induced by Chemotherapy (CIPN) VMD-3866 Gel, Placebo Gel - Chemotherapy-induced Peripheral Neuropathy, Chemotherapy-induced Neuropathic Pain | Phase 2 | Recruiting | VM Therapeutics LLC | 16 | 2025-12-12 | 2026-10-21 |
| (2R,6R)-Hydroxynorketamine for the Treatment of Neuropathic Pain Ketamine, (2R,6R)-hydroxynorketamine, Saline - Pain, Neuropathic | Phase 1 / Phase 2 | Recruiting | Rush University Medical Center | 25 | 2024-09-19 | 2026-08-03 |
| Botulinum Toxin A as Treatment for Chronic Postsurgical Pain Following Lung Cancer Surgery Onabotulinum Toxin A, Normal saline - Chronic Pain, Post-thoracotomy Pain Syndrome | Phase 1 / Phase 2 | Unknown | Allan Vestergaard Danielsen, MD | 30 | 2022-09-01 | 2021-11-09 |
| Transnasal Sphenopalatine Ganglia Block for Management of Chronic Migraines in Pediatric Patients Headache Journal, Sphenopalatine Block, Tx360 - Migraine in Children, Pain, Neuropathic | Phase 2 | Withdrawn | Washington University School of Medicine | 2021-01-02 | 2021-02-10 | |
| Ozone Therapy in Chemotherapy-induced Peripheral Neuropathy: RCT (O3NPIQ) Ozone, Oxygen - Chemotherapy-induced Peripheral Neuropathy, Pain, Neuropathic | Phase 2 / Phase 3 | Recruiting | Bernardino Clavo, MD, PhD | 42 | 2020-11-30 | 2026-09-25 |
| Valproic Acid for the Prevention of Post-Amputation Pain Valproic Acid, Cherry Syrup - Pain, Phantom, Pain, Neuropathic | Phase 2 | Completed | Duke University | 128 | 2013-12-01 | 2018-12-19 |
| Efficacy Study in Lumbosacral Radiculopathy Placebo, GS856553 - Pain, Neuropathic | Phase 2 | Completed | GlaxoSmithKline | 142 | 2010-01-07 | 2017-06-08 |
| Study in Neuropathic Pain Patients With Peripheral Nerve Injury GW856553, PLACEBO - Pain, Neuropathic | Phase 2 | Completed | GlaxoSmithKline | 168 | 2009-08-01 | 2017-02-17 |
| P38 Mitogen-activated Protein (Map) Kinase Inhibitor (SB-681323)Study In Patients With Neuropathic Pain SB681323, Placebo - Pain, Neuropathic | Phase 2 | Completed | GlaxoSmithKline | 50 | 2006-08-30 | 2017-08-22 |
Neuralgia (9) · Chronic Pain (3) · Pain (3) · Peripheral Nerve Injuries (2) · Agnosia (1) · Cancer Pain (1) · Disease (1) · Hypesthesia (1) · Pain, Postoperative (1) · Paresthesia (1) · Phantom Limb (1) · Somatoform Disorders (1)
Nervous System Diseases (9) · Neurologic Manifestations (9) · Neuromuscular Diseases (9) · Pathological Conditions, Signs and Symptoms (9) · Peripheral Nervous System Diseases (9) · Signs and Symptoms (9) · Pain (6) · Pathologic Processes (3) · Neurobehavioral Manifestations (2) · Perceptual Disorders (2) · Postoperative Complications (2) · Trauma, Nervous System (2) · Wounds and Injuries (2) · Mental Disorders (1) · Pain, Postoperative (1)
6-(5-((cyclopropylamino)carbonyl)-3-fluoro-2-methylphenyl)-N-(2,2-dimethylprpyl)-3-pyridinecarboxamide (1) · 6-hydroxynorketamine (1) · Ketamine (1) · Oxygen (1) · Ozone (1) · Saline Solution (1) · Sodium Chloride (1) · Sphenopalatine Ganglion Block (1) · Valproic Acid (1) · dilmapimod (1) · onabotulinum toxin A (1)
GlaxoSmithKline (3) · Allan Vestergaard Danielsen, MD (1) · Bernardino Clavo, MD, PhD (1) · Duke University (1) · Rush University Medical Center (1) · VM Therapeutics LLC (1) · Washington University School of Medicine (1)
Denmark (3) · United Kingdom (3) · United States (3) · Australia (2) · Germany (2) · Norway (2) · Russia (2) · Spain (2) · Sweden (2) · France (1)
Allan V Danielsen, MD (1) · Asokumar Buvanendran, MD (1) · Bernardino Clavo, MD, PhD (1) · Gustavo M Callico, Prof, PhD (1) · Jacob AuBuchon, MD (1) · Pedro G Serrano-Aguilar, MD, PhD (1) · Thomas E Buchheit, MD (1)
PMID 19260079, PMID 21427067, PMID 21575276, PMID 23102757, PMID 23549581, PMID 24687190, PMID 24733808, PMID 25699252, PMID 31779159, PMID 32379556, PMID 33738491
2019 (1)