26 completed, 7 recruiting, 7 unknown, 2 not yet recruiting. 24 Not applicable, 9 Phase 2, 5 Phase 3, 2 Early Phase 1, 2 Phase 4.
Follow Hypesthesia: new trials by email Literature Review of Hypesthesia trials Research Report on Hypesthesia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Vitamin B Complex for Inferior Alveolar Nerve Paresthesia Recovery Vitamin B Complex, Placebo - Paresthesia and Hypoesthesia | Phase 4 | Not yet recruiting | University of Sao Paulo | 50 | 2026-06-10 | 2026-05-20 |
| Neuroma-Associated Pain Management After Combat-Related Trauma in Ukraine cryoablation, Radiofrequency ablation alone - Pain Management, Quality of Life | Not applicable | Completed | Ukrainian Society of Regional Anesthesia and Pain Therapy | 100 | 2026-02-05 | 2026-10-19 |
| Comprehensive Multicenter Study on the Management of Acute Pain Following Thoracic Combat-Related Trauma in Ukraine Cryoablation, Radiofrequency ablation alone - Pain Management, Thoracic Trauma | Not applicable | Recruiting | Lviv National Medical University | 50 | 2026-01-01 | 2026-02-02 |
| Analgesic Efficacy and Safety of Topical VMD-3866 Gel in Management of Pain Induced by Chemotherapy (CIPN) VMD-3866 Gel, Placebo Gel - Chemotherapy-induced Peripheral Neuropathy, Chemotherapy-induced Neuropathic Pain | Phase 2 | Recruiting | VM Therapeutics LLC | 16 | 2025-12-12 | 2026-10-21 |
| Effects of Exercises and Electrical Current Application Aiming to Strengthen Neck and Shoulder Blades Muscles on Symptoms of a Pinched Nerve in the Neck Exercise Therapy, Superimposition of electrical muscle stimulation on active movement - Cervical Radiculopathy, Cervical Radicular Pain | Not applicable | Completed | European University of Lefke | 50 | 2025-12-01 | 2026-03-24 |
| Effect of J-Shaped Incision After Total Knee Arthroplasty (J-TKA) Conventional Midline Incision, J-shaped Incision - Osteoarthritis, Knee | Not applicable | Completed | Fatih Sultan Mehmet Training and Research Hospital | 62 | 2025-09-17 | 2026-05-29 |
| Comparative Analysis of Median Nerve Parameters for Carpal Tunnel Syndrome (CTS) Diagnosis: Ultrasound Versus Nerve Conduction Studies (NCS) Nerve Conduction Study - Carpal Tunnel Syndrome (CTS), Nerve Conduction | Not applicable | Not yet recruiting | Combined Military Hospital Kohat Pakistan | 50 | 2025-05-01 | 2025-04-15 |
| Ozone Treatment in Paresthesia (Numbness, Tingling) Secondary to Chemotherapy-induced Peripheral Neuropathy Ozone therapy, Oxygen (placebo) - Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia | Phase 2 / Phase 3 | Recruiting | Bernardino Clavo, MD, PhD | 42 | 2025-02-07 | 2026-09-18 |
| Gut Microbiome Profiles in Patients With Chemotherapy-induced Neuropathy in the RCT OzoParQT (NCT06706544). Ozone therapy, Oxygen (placebo) - Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia | Phase 2 / Phase 3 | Recruiting | Bernardino Clavo, MD, PhD | 42 | 2025-02-07 | 2026-09-25 |
| Comparison of the Results of Biostimulation Treatment of Inferior Alveolar Nerve Injury Using Nd:YAG and Diode Lasers With Different Wavelengths. Nd:YAG Laser Biostimulation, Diode Laser Biostimulation - Inferior Alveolar Nerve Injury, Neurosensory Disturbance | Not applicable | Completed | Ondokuz Mayıs University | 30 | 2024-10-27 | 2026-02-17 |
| Lidocaine Versus Bupivacaine in Orthognathic Surgery 10 cc of 0.25% bupivacaine hydrochloride with 1:200,000 epinephrine, 6.8 cc of 2% lidocaine hydrochloride with 1:100,000 epinephrine - Pain, Postoperative, Numbness | Phase 4 | Completed | Boston Children's Hospital | 64 | 2024-10-01 | 2026-08-04 |
| Peer Support for Patients With Diabetic Foot Ulcers Peer counseling group - Diabetic Foot Ulcer, Diabetic Wound | Not applicable | Unknown | Casa Colina Hospital and Centers for Healthcare | 24 | 2023-11-21 | 2023-12-06 |
| Effects of Cervical Stabilization Exercises and Vibration Application in Individuals With Parkinson's Disease Chattanooga Stabilizer pressure biofeedback, VibraSens - Focal Vibration Therapy (TechnoConcept - France), Telerehabilitation - Parkinson Disease | Not applicable | Unknown | Hacettepe University | 30 | 2023-08-30 | 2023-08-15 |
| Effects of Contemporary Cycling Saddle Designs on Penile Transcutaneus Oxygen and Carbon Dioxide Levels in Elite Road Cyclists Riding on a Stationary Trainer Biothesiometry, Transcutaneous blood gas monitoring, Cycling on a home trainer - Healthy, Cyclists | Not applicable | Completed | Milan Martínek | 14 | 2023-04-21 | 2025-12-30 |
| Multimodal Haptic Feedback for Plantar Sensory Substitution Haptic Device - Hypoesthesia | Not applicable | Completed | Shirley Ryan AbilityLab | 100 | 2023-04-20 | 2026-08-07 |
| Cybersickness in Different Multisensory Conditions in Virtual Reality Binaural beats - Cybersickness, Reduced Sensation | Not applicable | Completed | Federal University of Piaui | 10 | 2022-11-08 | 2023-11-08 |
| Prospective Study of Sensation and Satisfaction in Cancer and Transgender Mastectomy Patients Sensory testing - Sensation Disorders, Sensation, Phantom | Recruiting | Weill Medical College of Cornell University | 400 | 2022-02-09 | 2026-09-23 | |
| Stroking Versus Ergon Technique in Pregnant Women TENS - Lateral Cutaneous Nerve of Thigh Lesion | Not applicable | Unknown | Riphah International University | 24 | 2021-12-24 | 2022-12-27 |
| Observational Study on the Treatment of Trigeminal Neuralgia by Radiosurgery Trigeminal Neuralgia | Recruiting | Centre Hospitalier Princesse Grace | 150 | 2021-12-15 | 2025-02-19 | |
| Effect of Topical Lidocaine on Warm and Cold Sensation in Healthy Individuals Xylocaine spray 100mg/ml, Ethanol - Neuropathy;Peripheral, Thermal Hypesthesia | Not applicable | Unknown | University of Aarhus | 60 | 2021-03-01 | 2021-04-29 |
Showing 20 of 44. Sign in to see all of them.
Paresthesia (13) · Pain (8) · Neuralgia (5) · Anxiety Disorders (4) · Chronic Pain (4) · Agnosia (3) · Carpal Tunnel Syndrome (3) · Depression (3) · Parasomnias (3) · Peripheral Nervous System Diseases (3) · Colorectal Neoplasms (2) · Disease (2) · Fatigue (2) · Hyperalgesia (2)
Nervous System Diseases (44) · Neurologic Manifestations (44) · Pathological Conditions, Signs and Symptoms (44) · Signs and Symptoms (44) · Somatosensory Disorders (44) · Sensation Disorders (43) · Neuromuscular Diseases (13) · Peripheral Nervous System Diseases (10) · Pain (8) · Mental Disorders (6) · Pathologic Processes (6) · Neurobehavioral Manifestations (5) · Neoplasms (4) · Neoplasms by Site (4) · Perceptual Disorders (4)
Phentolamine (3) · Cryosurgery (2) · Oxygen (2) · Radiofrequency Ablation (2) · ALGRX-4975 (1) · Abdominoplasty (1) · Bariatric Surgery (1) · Blood Gas Monitoring, Transcutaneous (1) · Bupivacaine (1) · CD36 Antigens (1) · Capsaicin (1) · Carvedilol (1) · Cortisone (1) · Denervation (1) · Electroacupuncture (1)
Novalar Pharmaceuticals, Inc. (4) · Bernardino Clavo, MD, PhD (2) · Boston Children's Hospital (1) · Cantonal Hospital of St. Gallen (1) · Casa Colina Hospital and Centers for Healthcare (1) · Centre Hospitalier Princesse Grace (1) · Columbia Northwest Pharmaceuticals (1) · Columbia University (1) · Combined Military Hospital Kohat Pakistan (1) · Copenhagen University Hospital, Rigshospitalet (1) · European University of Lefke (1) · Fatih Sultan Mehmet Training and Research Hospital (1) · Federal University of Piaui (1) · Federal University of São Paulo (1) · H. Lee Moffitt Cancer Center and Research Institute (1)
United States (20) · Brazil (2) · Denmark (2) · Pakistan (2) · Spain (2) · Turkey (Türkiye) (2) · Ukraine (2) · Cyprus (1) · Czechia (1) · France (1) · Germany (1) · Monaco (1) · Norway (1) · South Korea (1) · Switzerland (1)
Athena Papas, DMD (2) · Bernardino Clavo, MD, PhD (2) · Ahmet Bozkurt, PD Dr. med. (1) · Alok Gupta, MD (1) · Arifulla Khan, MD (1) · Arun Jayaraman, PT, PhD (1) · Cathy Eng, MD, BA (1) · Charles L Loprinzi (1) · Ellen L Schaldemose, MD (1) · Elvio B Garcia, Professor (1) · Emily Rosario, PhD (1) · Erik Kubiak, MD (1)
PMID 16981050, PMID 18646107, PMID 18982397, PMID 26000320, PMID 26203063, PMID 28614678, PMID 33283264, PMID 33514270, PMID 34059410, PMID 35919449, PMID 37651553, PMID 39971386, PMID 41572235, PMID 42360437
P30CA015083 (1)