34 completed, 16 unknown, 14 recruiting, 6 terminated. 34 Not applicable, 15 Phase 2, 9 Phase 1, 5 Phase 4, 4 Phase 3.
Follow Peripheral Nerve Injuries: new trials by email Literature Review of Peripheral Nerve Injuries trials Research Report on Peripheral Nerve Injuries
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Blast-related Regional Anaesthesia and Peripheral nerVe Injury Evaluation Standardized Multimodal Analgesia, Ultrasound-Guided Regional Anaesthesia - Nerve Block, Nerve Blocks | Not applicable | Not yet recruiting | Ukrainian Society of Regional Anesthesia and Pain Therapy | 150 | 2026-12-23 | 2026-10-19 |
| Nerve Blocks or Combat Trauma: What Drives Peripheral Nerve Injury? Combat-Related Limb Injury, Nerve Block | Not yet recruiting | Ukrainian Society of Regional Anesthesia and Pain Therapy | 1000 | 2026-10-31 | 2026-10-09 | |
| High-Intensity Peripheral Magnetic Stimulation in Traumatic Peripheral Nerve Injury High-Intensity Peripheral Magnetic Stimulation, Sham Peripheral Magnetic Stimulation, Therapeutic Exercise Program - Peripheral Nerve Injuries, Traumatic Peripheral Nerve Injury | Not applicable | Recruiting | Gaziler Physical Medicine and Rehabilitation Education and Research Hospital | 40 | 2026-08-13 | 2026-09-22 |
| Early Functional Response as a Predictor of Clinical Outcomes in Hand Rehabilitation: A Prospective Feasibility Study Using a Digital Monitoring System Hand, Hand Therapy | Not yet recruiting | Hacettepe University | 60 | 2026-06-15 | 2026-04-13 | |
| Study Comparing Avance Nerve Graft and Autograft for Functional Recovery Following Mixed and Motor Peripheral Nerve Reconstruction Avance Nerve Graft, Sural nerve autograft - Peripheral Nerve Injury, Peripheral Nerve Discontinuity | Phase 4 | Recruiting | Axogen Corporation | 178 | 2026-06-11 | 2026-10-08 |
| Proximal Nerve Cryoablation Versus Perineuroma Cryoablation for Chronic Neuroma Pain After Combat-Related Amputation Perineuroma Cryoablation, Proximal Nerve Cryoablation - Neuroma, Cryoablation | Not applicable | Completed | Ukrainian Society of Regional Anesthesia and Pain Therapy | 50 | 2026-05-23 | 2026-10-26 |
| Continuous Observational Monitoring Program for Allay™ Hydrogel Cap Safety and Success Study Nerve Cap - Peripheral Nerve Injuries | Recruiting | Tulavi Therapeutics,Inc. | 1000 | 2026-05-06 | 2026-09-21 | |
| EMG-Triggered Electrical Stimulation After Median/Ulnar Nerve Repairs EMG-triggered electrical stimulation, Conventional physiotherapy group - Peripheral Nerve Injuries, Median Nerve Injury | Not applicable | Not yet recruiting | Pamukkale University | 26 | 2026-04-30 | 2026-04-16 |
| Safety, Tolerability, and Pharmacokinetics of ASCT-83 in Healthy Adults ASCT-83, Placebo - Neuropathic Pain | Phase 1 | Recruiting | Alcamena Stem Cell Therapeutics | 72 | 2026-01-06 | 2026-06-16 |
| A Study to Expand the Use of Symani® Surgical System for Peripheral Nerve Repair Symani® Surgical System, Manual Surgery - Nerve Injury, Peripheral Nerve Injuries | Not applicable | Recruiting | MMI (Medical Microinstruments, Inc.) | 100 | 2025-12-18 | 2026-02-03 |
| Analgesic Efficacy and Safety of Topical VMD-3866 Gel in Management of Pain Induced by Chemotherapy (CIPN) VMD-3866 Gel, Placebo Gel - Chemotherapy-induced Peripheral Neuropathy, Chemotherapy-induced Neuropathic Pain | Phase 2 | Recruiting | VM Therapeutics LLC | 16 | 2025-12-12 | 2026-10-21 |
| High-Purity Type I Collagen Nerve Wrapping in Peripheral Nerve Procedures: A Prospective Registry High-Purity Type I Collagen (HPTC) Nerve Wrap - Peripheral Nerve Injuries, Neuroma of Nerve Repair | Not applicable | Completed | Adichunchanagiri Institute of Medical Sciences, B G Nagara | 40 | 2025-12-09 | 2026-03-30 |
| Non-invasive Therapy to Drive Nerve Regeneration Acute Intermittent Hypoxia, Normoxia - Peripheral Nerve Injuries | Not applicable | Enrolling by invitation | University of Alberta | 80 | 2025-07-01 | 2026-02-09 |
| 4-AP Peripheral Nerve Crossover Trial 4-Aminopyridine, Placebo - Peripheral Nerve Injury, Crush Injury | Phase 2 | Recruiting | University of Arizona | 68 | 2025-04-21 | 2025-08-05 |
| A Comparison of NeuroSpan Bridge, NeuraGen Nerve Guide, and Nerve Autograft for Peripheral Nerve Repair NeuroSpan Bridge, NeuroGen Nerve Guide, Nerve Autograft - Peripheral Nerve Injuries | Not applicable | Recruiting | Auxilium Biotechnologies | 80 | 2025-03-21 | 2026-06-26 |
| This Study Will Evaluate the Effectiveness of NTX-001, a Surgical Nerve Repair Product When Used in People With Upper Extremity Nerve Lacerations. NTX-001 (PEG-Fusion) - Peripheral Nerve Injury Upper Limb, Peripheral Nerve Injury (PNI) | Phase 3 | Recruiting | Neuraptive Therapeutics Inc. | 98 | 2025-02-10 | 2026-10-06 |
| Ultrasound Guided Placental Growth Factor Vs Platelet Rich Plasma Injection in Peripheral Nerve Injury: an Interventional Study perineural injection - Peripheral Nerve Injury Upper Limb | Not applicable | Not yet recruiting | Assiut University | 75 | 2025-01-15 | 2024-10-15 |
| Effect of Nerve Stimulation on Sciatic Nerve Injury Pediatric Patients Faradic Nerve Stimulation Therapy+Standard Physiotherapy, Physiotherapy Standard Treatment with TENS machine therapy - Leg Pain, Peripheral Nerve Discontinuities | Not applicable | Recruiting | Azeem Hospital, Multan | 100 | 2024-11-18 | 2025-02-04 |
| Upper Extremity Functional Electrical Stimulation (FES) for Restoration of Upper Extremity Function After Spinal Cord Injury (SCI) MyndMove Short Term Therapy, Conventional Short Term Therapy, MyndMove Long Term Therapy - Spinal Cord Injuries, Peripheral Nerve Injuries | Not applicable | Recruiting | University of Miami | 60 | 2024-11-01 | 2026-04-23 |
| Mirror Therapy Combined With Contralaterally Controlled Functional Electrical Stimulation for Peripheral Nerve Injury mirror therapy, contralaterally controlled functional electrical stimulation, conventional physiotherapy - Peripheral Nerve Injury | Not applicable | Completed | National Taiwan University Hospital | 7 | 2024-03-29 | 2026-01-14 |
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Neuralgia (14) · Peripheral Nervous System Diseases (10) · Neuralgia, Postherpetic (6) · Chronic Pain (5) · Pain (5) · Agnosia (4) · Disease (4) · Neuroma (4) · Polyneuropathies (4) · Wounds and Injuries (4) · Nervous System Diseases (3) · Trauma, Nervous System (3) · Hyperalgesia (2) · Marijuana Abuse (2)
Neuromuscular Diseases (84) · Nervous System Diseases (81) · Trauma, Nervous System (81) · Wounds and Injuries (80) · Peripheral Nervous System Diseases (74) · Pathological Conditions, Signs and Symptoms (28) · Neurologic Manifestations (25) · Signs and Symptoms (24) · Pain (17) · Pathologic Processes (8) · Neoplasms (5) · Neuralgia (5) · Neurobehavioral Manifestations (5) · Perceptual Disorders (5) · Neoplasms by Histologic Type (4)
Mirror Movement Therapy (4) · Capsaicin (2) · Electric Stimulation (2) · Surveys and Questionnaires (2) · 4-Aminopyridine (1) · 6-(5-((cyclopropylamino)carbonyl)-3-fluoro-2-methylphenyl)-N-(2,2-dimethylprpyl)-3-pyridinecarboxamide (1) · Botulinum Toxins, Type A (1) · Etoricoxib (1) · GW406381X (1) · Lidocaine (1) · Nerve Conduction Studies (1) · Nerve Transfer (1) · Oxcarbazepine (1) · Physical Therapy Modalities (1) · Polyethylene Glycols (1)
Axogen Corporation (7) · Ruhr University of Bochum (3) · Ukrainian Society of Regional Anesthesia and Pain Therapy (3) · University of Alberta (3) · W. Dalton Dietrich (3) · Apurano Pharmaceuticals GmbH (2) · Assiut University (2) · Chang Gung Memorial Hospital (2) · GlaxoSmithKline (2) · Neuraptive Therapeutics Inc. (2) · University of Sao Paulo (2) · University of Utah (2) · Adichunchanagiri Institute of Medical Sciences, B G Nagara (1) · Alcamena Stem Cell Therapeutics (1) · Artgen Biotech (1)
United States (27) · Germany (8) · Canada (7) · United Kingdom (7) · Turkey (Türkiye) (6) · Spain (5) · Denmark (4) · Austria (3) · Sweden (3) · Taiwan (3) · Australia (2) · Belgium (2) · Brazil (2) · Bulgaria (2) · Czechia (2)
Seth Schulman, MD (2) · Yueh-Hsia Chen, PhD (2) · Adam Reid (1) · Admir Hadzic, Prof Dr (1) · Adriana Miclescu, MD, PhD, DEAA (1) · Ahmed S Sharaf, MsC (1) · Ala Elhelali, PhD (1) · Allan D. Levi, MD, PhD (1) · Allan Levi, MD, PhD (1) · Amira Mostafa El-sonbaty, lecturer (1) · Amy M Moore, MD (1) · Ana Ruiz, MD (1) · Awny M Asklany, MD (1) · Christoph Maier, Dr.med (1) · Christoph Maier, Prof. Dr. med. (1)
PMID 10194002, PMID 10811759, PMID 10961548, PMID 11386766, PMID 11533734, PMID 11580891, PMID 11762726, PMID 12625396, PMID 1301372, PMID 14641646, PMID 15068920, PMID 15206821, PMID 15217330, PMID 15647628, PMID 15785841, PMID 15862365, PMID 15899259, PMID 16019738, PMID 1725057, PMID 1843843, PMID 19800329, PMID 23466240, PMID 26786080, PMID 27634158, PMID 28158151, PMID 29661095, PMID 30679333, PMID 30908579, PMID 31858880, PMID 32685131, PMID 33791897, PMID 34554688, PMID 35005383, PMID 38147413, PMID 7067267, PMID 8393727, PMID 8441009, PMID 8676027, PMID 8994006, PMID 9285584, PMID 9602967, PMID 9680023, PMID 9862262
2009 (1), 2016 (1), R01NS111293 (1), R44NS145934 (1)