12 completed, 4 unknown, 2 recruiting, 1 active not recruiting. 6 Phase 2, 6 Phase 4, 4 Phase 1, 2 Early Phase 1, 2 Not applicable.
Follow onabotulinum toxin A: new trials by email Literature Review of onabotulinum toxin A trials Research Report on onabotulinum toxin A
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Optimal Intravesical Lidocaine Volume for Pain Relief During Office Intra-detrusor Onabotulinum Toxin a Injections Lidocaine 2% without vessel constrictor - Overactive Bladder, Overactive Bladder Syndrome | Phase 4 | Not yet recruiting | University of Louisville | 36 | 2024-12-01 | 2024-11-19 |
| Effect of Intradetrusor onabotulinumtoxinA Injection Versus Conservative Management on Female Sexual Function in Patients With Bladder Pain Syndrome Onabotulinum toxin A, Conservative management (dietary and behavioral) - Bladder Pain Syndrome, Female Sexual Dysfunction | Recruiting | Walter Reed National Military Medical Center | 159 | 2024-11-01 | 2024-12-11 | |
| Onabotulinum Toxin A (Botox) for the Treatment of Persistent Post-Stroke and Vascular Headache Botox 200 UNT Injection, Non Botox based Standard of Care Treatments for Headache/Migraine - Stroke (CVA) or TIA, Headache, Migraine | Phase 1 | Withdrawn | University of Alberta | 2023-12-01 | 2024-09-19 | |
| Botulinum Toxin A as Treatment for Chronic Postsurgical Pain Following Lung Cancer Surgery Onabotulinum Toxin A, Normal saline - Chronic Pain, Post-thoracotomy Pain Syndrome | Phase 1 / Phase 2 | Unknown | Allan Vestergaard Danielsen, MD | 30 | 2022-09-01 | 2021-11-09 |
| A Study Comparing the Safety, Efficacy, and Diffusion of Letibotulinum Toxin A Versus Other Botulinum Toxin Products in Adults With Moderate-to-Severe Forehead Wrinkles Letibotulinum toxin A, Prabotulinum toxin A, Onabotulinum toxin A - Forehead Rhytides | Phase 4 | Completed | Yonsei University | 20 | 2022-06-14 | 2025-07-18 |
| Chronic Migraine Prophylaxis: Ultrasound-Guided Greater Occipital Nerve Block Versus Medical Treatment Greater Occipital Nerve Block, Medical Treatment, bupivacaine or onabotulinum toxin A injection. - Greater Occipital Nerve Block, Medical Treatment | Not applicable | Unknown | Tanta University | 80 | 2022-05-01 | 2023-11-08 |
| Botulinum Toxin Injection for Sialorrhea in Cerebral Palsy onaBoNT-A - Sialorrhea | Completed | Cairo University | 61 | 2021-06-30 | 2023-10-27 | |
| A Study to Compare the Safety and Efficacy of Dysport® and Botox® in Adults With Upper Limb Spasticity. AboBoNT-A, OnaBoNT-A - Upper Limb Spasticity | Phase 4 | Completed | Ipsen | 464 | 2021-06-23 | 2026-07-09 |
| Split-Face Study Comparing Botox and Jeuveau in Treating Glabellar Lines PrabotulinumtoxinA, Onabotulinum toxin A - Glabellar Frown Lines | Early Phase 1 | Unknown | University of Southern California | 20 | 2021-01-01 | 2023-12-14 |
| Bladder Instillations Versus Onabotulinumtoxin A for Treatment of Interstitial Cystitis/Bladder Pain Syndrome Heparin & Alkalinized Lidocaine Bladder Instillation, Onabotulinum Toxin A - Interstitial Cystitis, Bladder Pain Syndrome | Phase 2 | Completed | Walter Reed National Military Medical Center | 58 | 2020-09-15 | 2023-10-12 |
| Efficacy of Prabotulinum and Onabotulinum Toxin-A for Facial Wrinkles Onabotulinum toxin A, Prabotulinumtoxin A - Face, Skin Fold | Phase 4 | Completed | Instituto de Oftalmología Fundación Conde de Valenciana | 26 | 2020-06-15 | 2023-05-03 |
| Intraoral Administration of Botox in Patients With Dentoalveolar Neuropathic Pain onabotulinum toxin A - Neuropathic Pain | Phase 2 | Completed | Isabel Moreno Hay | 8 | 2019-09-11 | 2026-07-30 |
| Standard Injections Versus Reduced Injections for Intravesical onabotulinumtoxinA Treatment of Overactive Bladder onaBoNT-A - Overactive Bladder | Phase 4 | Recruiting | Walter Reed National Military Medical Center | 184 | 2019-07-01 | 2020-04-28 |
| Instillation of Botox in the Bladder in Women With Overactive Bladder (OAB) onabotulinum toxin A - Overactive Bladder | Phase 2 | Completed | The Hospital of Vestfold | 14 | 2016-03-01 | 2018-11-26 |
| Sustained onabotulinumtoxinA Therapeutic Benefits in Patients With Chronic Migraine Onabotulinum toxin A - Migraine Disorders | Phase 4 | Completed | Corfu Headache Clinic | 56 | 2015-04-01 | 2018-07-30 |
| Intraprostatic Injection of Botulinum Toxin A Versus Ethanol for Treatment of Patients With Benign Prostatic Hyperplasia Botulinum toxin A, Ethanol - Male, Ultrasonography | Not applicable | Completed | Cairo University | 90 | 2013-12-01 | 2017-12-28 |
| A Pilot Study Testing Onabotulinum Toxin A Versus Incobotulinum Toxin A Injections for Facial Wrinkles Onabotulinum Toxin A, Incobotulinum Toxin A - Wrinkles | Early Phase 1 | Active not recruiting | Northwestern University | 20 | 2013-11-01 | 2026-07-01 |
| OnabotulinumtoxinA (onaBoNT-A) Versus Oral Oxybutynin ER onaBoNT-A, Oxybutynin ER - Overactive Bladder | Phase 3 | Unknown | Christopher Patrick Smith | 36 | 2013-08-01 | 2016-08-30 |
| Use of Botox to Treat Scrotal Pain Botox - Scrotal Pain | Phase 1 | Completed | Mount Sinai Hospital, Canada | 20 | 2013-03-01 | 2014-09-01 |
| Effectiveness of onaBoNT-A vs Oral Tamsulosin in Men With BPH and LUTS onaBoNT-A + placebo, Tamsulosin + placebo - Benign Prostatic Hyperplasia, Lower Urinary Track Symptoms | Phase 2 | Completed | VA Office of Research and Development | 63 | 2012-06-01 | 2021-10-05 |
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Urinary Bladder, Overactive (4) · Cystitis, Interstitial (2) · Migraine Disorders (2) · Neuralgia (2) · Prostatic Hyperplasia (2) · Urinary Incontinence (2) · Chronic Pain (1) · Facies (1) · Headache (1) · Hemorrhagic Stroke (1) · Hereditary Sensory and Autonomic Neuropathies (1) · Infections (1) · Lower Urinary Tract Symptoms (1) · Pain, Postoperative (1) · Restless Legs Syndrome (1)
Walter Reed National Military Medical Center (3) · Cairo University (2) · Allan Vestergaard Danielsen, MD (1) · Christopher Patrick Smith (1) · Corfu Headache Clinic (1) · Instituto de Oftalmología Fundación Conde de Valenciana (1) · Ipsen (1) · Isabel Moreno Hay (1) · Mount Sinai Hospital, Canada (1) · National Institute of Neurological Disorders and Stroke (NINDS) (1) · Northwestern University (1) · Tanta University (1) · The Hospital of Vestfold (1) · University of Alberta (1) · University of Louisville (1)
United States (11) · Canada (3) · Egypt (3) · Denmark (1) · France (1) · Mexico (1) · Norway (1) · Puerto Rico (1) · South Korea (1)
Allan V Danielsen, MD (1) · Angela DiCarlo-Meacham, MD (1) · Christopher P Smith, MD (1) · Christopher P. Smith, MD (1) · Fatta Nahab, MD (1) · Hjalmar A Schiotz, MD, PhD (1) · Jeffrey P Okeson, DMD (1) · Keith Jarvi, MD (1) · Mohammed S ElSheemy, Ass. Prof. (1) · Murad Alam, MD (1) · Muzaffar M Siddiqui, MD (1) · Sean Francis, MD (1) · Yonathan Garfias, PhD (1)
PMID 15126771, PMID 18461049, PMID 18478352, PMID 19054163, PMID 21791356, PMID 23098762, PMID 25164919, PMID 25311357, PMID 25500317, PMID 26233808, PMID 26381856, PMID 27910097, PMID 28840969, PMID 29765218, PMID 30152015, PMID 30232673, PMID 30617735, PMID 30893169, PMID 34562231, PMID 38768800, PMID 42159955
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