13 completed, 2 terminated, 2 unknown, 1 not yet recruiting. 4 Not applicable, 4 Phase 2, 4 Phase 4, 3 Phase 1, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Completed 3, Unknown 1 |
| Phase 2 | 4 | Completed 3, Unknown 1 |
| Phase 4 | 4 | Completed 2, Not yet recruiting 1, Terminated 1 |
| Phase 1 | 3 | Completed 3 |
| Phase 3 | 3 | Completed 2, Terminated 1 |
Follow Clomipramine: new trials by email Literature Review of Clomipramine trials Research Report on Clomipramine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy of Hydroxyzine for Patients With Panic Disorder Hydroxyzine, Escitalopram Oxalate - Panic Disorder | Phase 4 | Not yet recruiting | Sultan Qaboos University | 80 | 2023-12-30 | 2023-02-21 |
| Pharmacovigilance in Gerontopsychiatric Patients Phenobarbital, Phenytoin, Carbamazepine - Dementia, Depression | Phase 3 | Terminated | Hannover Medical School | 407 | 2015-01-01 | 2018-02-28 |
| Drug-Drug Interaction of Clomipramine HCl and Sildenafil Citrate in Healthy Males Treatment 1, Treatment 2, Treatment 3 - Healthy | Phase 1 | Completed | CTC Bio, Inc. | 30 | 2014-01-01 | 2014-09-15 |
| Interpersonal Psychotherapy for Treatment Resistant Depression IPT+ antidepressant drugs, fluoxetine, sertraline - Treatment Resistant Depression | Not applicable | Unknown | Hospital de Clinicas de Porto Alegre | 74 | 2013-04-01 | 2013-07-11 |
| Trial of PED-1 in Male Patients With Premature Ejaculation Clomipramine - Premature Ejaculation | Phase 3 | Completed | Symyoo | 159 | 2011-09-01 | 2012-10-03 |
| Phase 2 Trial of PED-1 and PED-2 in Male Patients With Premature Ejaculation Clomipramine - Premature Ejaculation | Phase 2 | Completed | Symyoo | 104 | 2010-09-01 | 2012-10-03 |
| Efficacy of Antidepressants in Chronic Back Pain cognitive behavioral therapy, desipramine hydrochloride, benztropine mesylate 0.125 mg daily - Back Pain | Phase 2 | Completed | VA Office of Research and Development | 142 | 2010-01-01 | 2016-11-29 |
| Continuation Electroconvulsive Therapy (C-ECT) for Relapse Prevention in Major Depression C-ECT, PHARMACOTHERAPY - Depression | Phase 4 | Terminated | Hospital Universitari de Bellvitge | 104 | 2009-07-01 | 2015-08-31 |
| Assessment of Pituitary Adenylate Cyclase Activating Polypeptide-Brain Derived Neurotrophic Factor (PACAP-BDNF) Signaling System Involvement in Etiology and Treatment of Major Depression SSRI; SNRI; TCA - Major Depression | Not applicable | Completed | Tirat Carmel Mental Health Center | 100 | 2009-06-01 | 2012-07-26 |
| Predicting Medication Response in Obsessive Compulsive Disorder clomipramine, escitalopram, duloxetine - Obsessive Compulsive Disorder | Not applicable | Completed | Sunnybrook Health Sciences Centre | 26 | 2009-04-01 | 2013-01-31 |
| Using Drug Augmentation to Treat Obsessive Compulsive Disorder Patients Who Did Not Respond to Previous Treatment Clomipramine (fluoxetine plus clomipramine), Quetiapine (fluoxetine plus quetiapine), Placebo (fluoxetine plus placebo) - Obsessive Compulsive Disorder | Phase 4 | Completed | University of Sao Paulo | 54 | 2007-05-01 | 2017-10-30 |
| Quetiapine Augmentation Versus Clomipramine Augmentation of SSRI for Obsessive-compulsive Disorder Patients Quetiapine, Clomipramine - Obsessive Compulsive Disorder | Phase 4 | Completed | University of Sao Paulo | 21 | 2006-01-01 | 2017-10-27 |
| Treatment of Obsessive Compulsive Disorder in Children Serotonin reuptake inhibitors management, Cognitive behavioral therapy by a psychologist, Instructional cognitive behavioral therapy by a psychiatrist - Obsessive-Compulsive Disorder | Phase 3 | Completed | Duke University | 124 | 2003-09-01 | 2014-07-29 |
| Phase II Randomized Study of Intravenous Versus Oral Clomipramine in Patients With Obsessive Compulsive Disorder Clomipramine - Obsessive-Compulsive Disorder | Phase 2 | Unknown | National Center for Research Resources (NCRR) | 76 | 1999-10-01 | 2005-06-24 |
| Effect of Antidepressants on Back Pain Desipramine, Fluoxetine, Benztropine - Back Pain, Sciatica | Phase 2 | Completed | US Department of Veterans Affairs | 130 | 1999-04-01 | 2012-06-05 |
| Citalopram vs Clomipramine vs Placebo in Recurrent Depression Citalopram, Clomipramine, placebo - Depression | Not applicable | Completed | University of Aarhus | 59 | 1997-10-01 | 2012-04-11 |
| To Demonstrate the Relative Bioavailability of Geneva and Basel (Anafranil) 25 mg Clomipramine Hydrochloride Capsules Under Fed and Fasted Conditions Geneva 25 mg Clomipramine Hydrochloride Capsules Under Fasting Conditions, Geneva 25 mg Clomipramine Hydrochloride Capsules Under Fed Conditions, Basel (Anafranil) 25 mg Clomipramine Hydrochloride Capsules Under Fed Conditions - Depression | Phase 1 | Completed | Sandoz | 18 | 1994-04-01 | 2017-03-28 |
| To Demonstrate the Relative Bioavailability of Geneva and Basel (Anafranil) 25 mg Clomipramine Hydrochloride Capsules Under Fasted Conditions Clomipramine Hydrochloride 25 mg Capsules (Geneva Pharmaceuticals), Anafranil Clomipramine Hydrochloride 25 mg Capsules (Basel) - Depression | Phase 1 | Completed | Sandoz | 36 | 1992-11-01 | 2017-03-28 |
Depression (6) · Obsessive-Compulsive Disorder (5) · Premature Ejaculation (3) · Anxiety Disorders (2) · Back Pain (2) · Agnosia (1) · Chronic Pain (1) · Dementia (1) · Depressive Disorder, Major (1) · Depressive Disorder, Treatment-Resistant (1) · Mental Disorders (1) · Neurologic Manifestations (1) · Panic Disorder (1) · Psychophysiologic Disorders (1) · Rare Diseases (1)
Sandoz (2) · Symyoo (2) · University of Sao Paulo (2) · CTC Bio, Inc. (1) · Duke University (1) · Hannover Medical School (1) · Hospital Universitari de Bellvitge (1) · Hospital de Clinicas de Porto Alegre (1) · National Center for Research Resources (NCRR) (1) · Sultan Qaboos University (1) · Sunnybrook Health Sciences Centre (1) · Tirat Carmel Mental Health Center (1) · US Department of Veterans Affairs (1) · University of Aarhus (1) · VA Office of Research and Development (1)
United States (4) · Brazil (3) · South Korea (3) · Canada (1) · Germany (1) · Israel (1) · Spain (1)
Juliana B Diniz, MD (2) · Richard Lalonde, Pharm.D. (2) · Albert Pinhasov, PhD (1) · Anatoly Kreinin, MD, PhD (1) · Helge Frieling, Prof., MD (1) · John S March, MD MPH (1) · Joseph Farah, MD (1) · Joseph H Atkinson, MD (1) · Joseph H. Atkinson, MD (1) · Kamal Farhat, MD (1) · Klaudia Rybalksy, MD (1) · Leon Raskin, PhD (1) · Lorrin Koran (1) · Marcelo PA Fleck, MD,PhD (1) · Mikel Urretavizcaya Sarachaga, MD, PhD (1)
PMID 17414235, PMID 19183470, PMID 19578654, PMID 21934055, PMID 22020357, PMID 25457929, PMID 26799332, PMID 28412602, PMID 32068667
2005 (2), R01MH055121 (1)