18 completed, 8 recruiting, 5 unknown, 3 active not recruiting. 17 Not applicable, 4 Phase 2, 2 Phase 4, 1 Early Phase 1, 1 Phase 1.
Follow Neurocognitive Dysfunction: new trials by email Literature Review of Neurocognitive Dysfunction trials Research Report on Neurocognitive Dysfunction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Neurocognitive Deficit After Paediatric Transplantation: Understanding the Role of Environment and Physical Function HSCT, Pediatric Cancer | Not yet recruiting | Copenhagen University Hospital, Rigshospitalet | 100 | 2026-02-15 | 2026-02-20 | |
| Monitoring Neurocognitive Dysfunction and the Impact of Metabolism and Physical Capacity After Paediatric HSCT Stem Cell Transplant, Late Effect | Not yet recruiting | Copenhagen University Hospital, Rigshospitalet | 175 | 2025-09-01 | 2025-09-04 | |
| Remotely Supervised tDCS+ for Complex Attention in mTBI (Cognetric) Active tDCS and Cognitive Training Intervention, Sham tDCS and Cognitive Training Intervention - Brain Concussion, Brain Trauma | Not applicable | Recruiting | United States Naval Medical Center, San Diego | 160 | 2024-07-25 | 2025-11-12 |
| Early Severe Illness TrAnslational BioLogy InformaticS in Humans Phelebotomy, Broncheoalveolar Lavage, Tracheal Aspirate - Sepsis, ARDS | Recruiting | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 1000 | 2024-04-26 | 2025-10-06 | |
| Neuro-cognitive Function 1 Year Post ICU Discharge Among VV ECMO Survivors VV ECMO - Neurocognitive Dysfunction | Completed | Meir Medical Center | 10 | 2024-03-01 | 2025-05-11 | |
| Evaluation of Memantine in the Preservation of Memory and Neurocognition Following CSI Memantine Oral Tablet - Neurocognitive Dysfunction | Phase 3 | Recruiting | Tata Memorial Centre | 101 | 2024-02-22 | 2025-04-09 |
| The DANCEREX Proof-of-Concept Study for Chronic Neurological Disorders DANCEREX-DTx, Multidimensional dance-based program, Educational Program - Sclerosis, Multiple, Neurocognitive Impairment, Mild | Not applicable | Recruiting | Fondazione Don Carlo Gnocchi ETS | 192 | 2024-01-31 | 2025-01-10 |
| Ca-Mg Butyrate in Gulf War Illness Cal-Mag Butyrate, Placebo - Gulf War Illness, Chronic Fatigue | Phase 2 | Recruiting | VA Office of Research and Development | 120 | 2024-01-15 | 2026-10-19 |
| Cognitive Functioning and Health Related Quality of Life in Retinoblastoma Survivors Neuropsychological assesment, Psychosocial functioning and quality of life (questionnaires), Parental psychosocial functioning (questionnaires) - Retinoblastoma, Neurocognitive Dysfunction | Enrolling by invitation | Amsterdam University Medical Center | 240 | 2023-10-26 | 2025-12-04 | |
| Hyperbaric Oxygen Therapy for Post-COVID-19 Syndrome Hyperbaric oxygen, Sham - Covid19, Neurocognitive Dysfunction | Not applicable | Recruiting | Assaf-Harofeh Medical Center | 91 | 2023-06-01 | 2026-04-21 |
| Perioperative Multimodal General AnesTHesia Focusing on Specific CNS Targets in Patients Undergoing carDiac surgERies EEG Monitoring, Ropivacaine, Ketamine - Postoperative Delirium, Hemodynamic Instability | Not applicable | Completed | Beth Israel Deaconess Medical Center | 70 | 2023-02-28 | 2025-11-26 |
| Intervention With Cerebral Embolic Protection in TEVAR: Gaseous Protection CO2 flushing, Saline flushing - Stroke, Silent Cerebral Infarction | Not applicable | Unknown | Imperial College London | 120 | 2022-11-14 | 2023-10-23 |
| Passive Sensor Identification of Digital Biomarkers to Assess Effects of Orally Administered Nicotinamide Riboside Emerald Device Monitoring - Alzheimer Disease, Dementia Alzheimers | Recruiting | Mclean Hospital | 40 | 2022-05-31 | 2025-11-06 | |
| Impact and Sequelae of High Ventilatory Drive in Critically Ill COVID-19 Patients COVID-19, Critical Illness | Unknown | Corporacion Parc Tauli | 126 | 2021-11-15 | 2022-05-05 | |
| An 18-year Follow-up Study on OSA in a Population-based Cohort Epidemiology, Natural History | Completed | Chinese University of Hong Kong | 202 | 2021-10-20 | 2025-12-15 | |
| Assessing Neurocognition After Cerebrovascular Intervention Neurocognitive Assessments, Measurements of inflammatory biomarkers, Carotid Artery Stenting - Carotid Artery Diseases, Neurocognitive Dysfunction | Not applicable | Recruiting | University of California, San Diego | 20 | 2021-07-15 | 2025-02-06 |
| Long-term Neurocognitive and Psychiatric Consequences in Severe COVID-19 Survivors. Exposure: COVID-19 severity - Covid19, Neurocognitive Dysfunction | Unknown | Pontificia Universidad Catolica de Chile | 80 | 2021-05-24 | 2021-08-31 | |
| Long-Term Functional, Quality-of-Life, Neuropsychological and Cognitive Outcomes in COVID-19 Critical Illness Survivors Covid19, ARDS | Unknown | University of Zurich | 200 | 2021-05-07 | 2021-05-11 | |
| tDCS and Cognitive Training in Active Duty Service Members With Mild TBI: A Pilot Study active tDCS and cognitive training intervention, sham tDCS and cognitive training intervention - Brain Concussion, Brain Trauma | Not applicable | Completed | United States Naval Medical Center, San Diego | 56 | 2021-01-19 | 2025-11-12 |
| Prospective Evaluation on Cognitive Function and Its Associated Genetic Vulnerability in Cannabis Users Genome analysis - Cannabis Use, Neurocognitive Dysfunction | Completed | The University of Hong Kong | 110 | 2020-11-01 | 2026-03-27 |
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Cognition Disorders (42) · Cognitive Dysfunction (5) · COVID-19 (4) · Brain Concussion (3) · Critical Illness (3) · Dementia (3) · Psychotic Disorders (3) · Schizophrenia (3) · Alcohol Drinking (2) · Autoimmune Diseases (2) · Brain Injuries (2) · Brain Injuries, Traumatic (2) · Endocrine System Diseases (2) · Inflammation (2) · Memory Disorders (2)
Mental Disorders (41) · Neurocognitive Disorders (40) · Nervous System Diseases (13) · Pathological Conditions, Signs and Symptoms (12) · Brain Diseases (9) · Central Nervous System Diseases (9) · Pathologic Processes (8) · Respiratory Tract Diseases (8) · Infections (7) · Lung Diseases (6) · RNA Virus Infections (6) · Virus Diseases (6) · Immune System Diseases (5) · Neurobehavioral Manifestations (5) · Neurologic Manifestations (5)
Transcranial Direct Current Stimulation (3) · Atorvastatin (1) · Cobicistat (1) · Darunavir (1) · Dexmedetomidine (1) · Emtricitabine (1) · Functional Residual Capacity (1) · Genome-Wide Association Study (1) · Hyperbaric Oxygenation (1) · Ketamine (1) · Maraviroc (1) · Melatonin (1) · Memantine (1) · Minocycline (1) · Propofol (1)
Tri-Service General Hospital (TSGH) (3) · Copenhagen University Hospital, Rigshospitalet (2) · Duke University (2) · Metagenics, Inc. (2) · United States Naval Medical Center, San Diego (2) · University of California, San Diego (2) · Amsterdam University Medical Center (1) · Assaf-Harofeh Medical Center (1) · Beth Israel Deaconess Medical Center (1) · Charite University, Berlin, Germany (1) · Chiang Mai University (1) · Children's Hospital Los Angeles (1) · Chinese University of Hong Kong (1) · Corporacion Parc Tauli (1) · Folktandvården Stockholms län AB (1)
United States (17) · Canada (3) · Israel (3) · Taiwan (3) · Denmark (2) · Italy (2) · Chile (1) · China (1) · Germany (1) · Hong Kong (1) · India (1) · Netherlands (1) · Spain (1) · Sweden (1) · Switzerland (1)
Hsin-An Chang, M.D. (3) · Joseph Lamb, MD (2) · Lars D Hungerford, PhD (2) · Aleks Leligdowicz, MD PhD (1) · Alexander A Khalessi, MD (1) · Annette C. Moll, MD PhD (1) · Arnoldo Riquelme, PhD (1) · Ashraf S Habib, MD (1) · Balachundhar Subramaniam, MD,MPH,FASA (1) · Carolina Mendez, PhD (1) · Ching Ching, Kate Dr. CHAN (1) · Claudia Spies, MD, Prof. (1) · Constanza Caneo, MD (1) · David R Santiago-Dieppa, MD (1)
PMID 31362034, PMID 33096356, PMID 34107933, PMID 34539329, PMID 35444514, PMID 36649152, PMID 37026177, PMID 37105705, PMID 37301934, PMID 37906406, PMID 38564243, PMID 39989365, PMID 40144043, PMID 41673604
I01CX002372 (1), K01AA026005 (1), U01AA020797 (1), U01AA026225 (1), U19AI135972 (1)