278 completed. 278 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 278 | Completed 278 |
Follow Mouth Diseases: new trials by email Literature Review of Mouth Diseases trials Research Report on Mouth Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of the Anti-plaque Effect of a Bioflavonoid-based Antiseptic Mouthwash Bioflavonoid mouthwash, Chlorhexidine 0.12% mouthwash - Gingival Inflammation, Dental Plaque Accumulation | Phase 4 | Completed | University of Barcelona | 24 | 2026-03-02 | 2026-09-17 |
| Comparison Between the Effect of Triclosan Toothpaste and Chlorhexidine Mouthwash on Gingival Health in a Group of Fixed Orthodontic Patients: A Randomized Controlled Clinical Trial Triclosan 0.3% toothpaste, sodium fluoride 0.24% toothpaste, Chlorhexidine 0.2% mouthwash - Gingival Inflammation | Phase 4 | Completed | University of Science and Technology, Yemen | 60 | 2026-02-14 | 2026-09-11 |
| Calcium Hydroxide Versus Triple Antibiotic Paste for Pain After Root Canal Treatment Calcium Hydroxide (CH), Triple Antibiotic Paste - Apical Periodontitis, Pulp Necrosis | Phase 4 | Completed | Rehman Medical Institute - RMI | 138 | 2026-02-01 | 2026-11-06 |
| Efficacy of Coconut Gel Compared to Corticosteroid Gel in the Management of Oral Lichen Planus Coconut oil, Triamcinolone Acetonide - Oral Lichen Planus | Phase 4 | Completed | Ain Shams University | 36 | 2025-11-11 | 2026-10-02 |
| Adjunctive Topical Melatonin Gel in Non-Surgical Periodontal Therapy for Periodontitis Topical 5% Melatonin Gel, Placebo - Periodontal Disease, Melatonin | Phase 4 | Completed | Liaquat College of Medicine and Dentistry | 30 | 2025-11-03 | 2026-05-26 |
| Melatonin Loaded in Injectable Platelet-Rich Fibrin in the Management Periodontitis Melatonin-Loaded Injectable Platelet-Rich Fibrin, injectible platelet rich fibrin (i-PRF ), scaling and root planning - Periodontitis Stage II | Phase 4 | Completed | Al-Azhar University | 30 | 2025-11-01 | 2026-11-09 |
| Ultrasound-guided Combined Perineural and Intramuscular Dextrose Injection for Management of Refractory Bell's Palsy Ultrasound-guided combined perineural and intramuscular dextrose injection. - Bell Palsy | Phase 4 | Completed | Al-Azhar University | 30 | 2025-10-10 | 2026-07-27 |
| Comparative Efficacy of Floss and Essential Oil/CPC+Zn Mouthwashes in Reducing Dental Plaque and Gingivitis Mouthwash, Floss, Toothbrush - Dental Plaque, Gingivitis | Phase 4 | Completed | Colgate Palmolive | 228 | 2025-07-07 | 2025-10-30 |
| Effect of Zinc Oxide Ointment on Recurrent Aphthous Stomatitis zinc oxide, Placabo - Recurrent Aphthous Stomatitis | Phase 4 | Completed | Faculty of Dental Medicine for Girls | 100 | 2025-06-30 | 2026-05-04 |
| Clinical and Microbiological Evaluation Of The Efficacy Of Herbal Mouthwashes in Gingivitis Tea tree oil, Thyme oil hydrosol, LISTERINE ZERO Alcohol Mouthwash COOL MINT - Periodontal Diseases | Phase 4 | Completed | Altinbas University | 52 | 2025-02-28 | 2026-08-13 |
| Melatonin Gel as an Adjuvant in the Surgical Management of Intrabony Defects Melatonin gel mixed with xenograft, Xenograft - Periodontal Disease, AVDC Stage 3 | Phase 4 | Completed | Ain Shams University | 20 | 2025-01-01 | 2025-08-29 |
| The Efficacy of Amnion Chorion Allograft in Management of Gingival Recession. Amnion Chorion membrane, connective tissue graft - Gingival Recession, Localized | Phase 4 | Completed | Minia University | 28 | 2024-08-01 | 2025-05-29 |
| The Efficacy of Erythropoietin Oral Gel Versus Erythropoietin Mouthwash in the Management of Recurrent Aphthous Stomatitis Epoetin 4000, Placebo - Recurrent Aphthous Stomatitis | Phase 4 | Completed | Future University in Egypt | 60 | 2024-07-01 | 2025-08-26 |
| The Efficacy of Selenium as an Alternative or Complementary Topical Treatment of Oral Lichen Planus Triamcinolone Acetonide 0.1% Oint, Tacrollimus Topical, Selenium - Lichen Planus, Oral | Phase 4 | Completed | Al-Azhar University | 50 | 2024-05-01 | 2025-12-31 |
| Immunogenicity of Japanese Encephalitis Vaccine Co-administered With Measles-Mumps-Rubella Vaccine (MMR) Vero cell-drived inactive Japanese encephalitis vaccine, Measles-Mumps-Rubella Vaccine - Japanese Encephalitis, Measles | Phase 4 | Completed | Liaoning Chengda Biotechnology CO., LTD | 408 | 2024-03-02 | 2025-08-28 |
| Non-surgical Treatment of Peri-implantitis Using Chitosan Brush and Tetracycline Slurry Labrida Bioclean, Tetracycline slurry - Periimplantitis, Periimplant Diseases | Phase 4 | Completed | Aristotle University Of Thessaloniki | 40 | 2024-02-05 | 2026-01-27 |
| Effectiveness of Postoperative Topical and Oral Antibiotics on Impacted Mandibular 3rd Molar Surgery. Topical Antibiotic, Oral antibiotic therapy - Impacted Tooth, Postoperative Complications in Maxillofacial Surgery | Phase 4 | Completed | Liaquat College of Medicine and Dentistry | 90 | 2024-02-01 | 2026-05-12 |
| Efficacy and Safety of add-on Apremilast Versus add-on Methotrexate in Patients With Oral Lichen Planus Prednisolone, Apremilast, Methotrexate - Oral Lichen Planus | Phase 4 | Completed | All India Institute of Medical Sciences, Bhubaneswar | 64 | 2024-01-26 | 2025-12-03 |
| The Efficacy of Thyme Honey Mouth Rinse on Polypharmacy-induced Xerostomia Honey Mouthwash, Normal saline - Xerostomia | Phase 4 | Completed | Ain Shams University | 32 | 2024-01-15 | 2025-04-29 |
| Intravenous Dexamethasone on Postoperative Pain and Complications in Jaw Surgery Dexamethasone - Tooth Extraction Status Nos, Cysts Dental | Phase 4 | Completed | Selcuk University | 60 | 2024-01-01 | 2026-06-29 |
Showing 20 of 278. Sign in to see all of them.
Periodontitis (48) · Chronic Periodontitis (41) · Gingivitis (37) · Periodontal Diseases (31) · Gingival Recession (18) · Peri-Implantitis (13) · Lichen Planus, Oral (12) · Measles (11) · Mumps (11) · Xerostomia (11) · Rubella (10) · Dental Plaque (9) · Head and Neck Neoplasms (9) · Mucositis (9) · Sjogren's Syndrome (9)
Stomatognathic Diseases (278) · Periodontal Diseases (151) · Pathological Conditions, Signs and Symptoms (71) · Infections (65) · Gingival Diseases (57) · Pathologic Processes (56) · Disease Attributes (43) · Periodontitis (43) · Chronic Disease (41) · Salivary Gland Diseases (32) · Musculoskeletal Diseases (30) · Skin and Connective Tissue Diseases (29) · Tooth Diseases (29) · Periodontal Atrophy (28)
Amoxicillin (12) · Chlorhexidine (10) · Metronidazole (10) · Root Planing (10) · Tooth Exfoliation (10) · Photochemotherapy (6) · Sodium Chloride (6) · Triamcinolone Acetonide (6) · Measles-Mumps-Rubella Vaccine (5) · Prednisolone (5) · Triclosan (5) · enamel matrix proteins (5) · hydrated silica gel-based toothpaste (5) · Alloderm (4) · Epinephrine (4)
Ain Shams University (13) · Colgate Palmolive (9) · University of Sao Paulo (9) · Tatyasaheb Kore Dental College (8) · University of Campinas, Brazil (7) · GlaxoSmithKline (6) · Al-Azhar University (4) · Procter and Gamble (4) · Proed, Torino, Italy (4) · University of Taubate (4) · Cairo University (3) · Dr. D. Y. Patil Dental College & Hospital (3) · Novartis (3) · Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre (3) · Aga Khan University (2)
United States (40) · Egypt (27) · Brazil (26) · India (14) · Italy (11) · Turkey (Türkiye) (11) · Spain (10) · Germany (8) · China (7) · Canada (6) · Sweden (6) · United Kingdom (6) · France (5) · Pakistan (5) · Switzerland (5)
Enilson A Sallum, PhD (5) · Daniele Cardaropoli, DDS (4) · Ahmed Y Gamal, Professor (2) · Chhaju Ram Goyal, DDS (2) · Fernando O Costa, PhD (2) · Girish D Deore, BDS (2) · Gustavo Avila-Ortiz, DDS, MS, PhD (2) · Jose R Cortelli, PhD (2) · Michael Lynch, DMD, PhD (2) · Ronaldo B Santana, DDS,MScD,DSc (2) · Aaron Biesbrock, DMD, PhD (1) · Abdullah AlAlwani, DDS (1) · Ahmed Khalil, professor (1)
PMID 33197289, PMID 16018754, PMID 26285807, PMID 10328647, PMID 10630935, PMID 11208206, PMID 11276867, PMID 11516756, PMID 11702237, PMID 11989392, PMID 12108756, PMID 12190139, PMID 12622859, PMID 12673463, PMID 12787214, PMID 1298430, PMID 14121956, PMID 14697016, PMID 14710766, PMID 14742657, PMID 15225944, PMID 15341352, PMID 15455740, PMID 15464564, PMID 15655026, PMID 15703760, PMID 16424527, PMID 16480503, PMID 16553634, PMID 16700739, PMID 16759558, PMID 17000452, PMID 17068477, PMID 17355365, PMID 17824884, PMID 18088730, PMID 18724841, PMID 18724858, PMID 18771373, PMID 18849193, PMID 19146143, PMID 19254123, PMID 19305145, PMID 19538334, PMID 19639449, PMID 19678861, PMID 19722800, PMID 19968743, PMID 20151809, PMID 20350159
2014 (2), 2008 (1), 2017 (1), P20RR017696 (1), R01CA091912 (1)