111 completed, 44 unknown, 24 terminated, 14 withdrawn. 74 Phase 2, 56 Not applicable, 33 Phase 3, 21 Phase 1, 11 Phase 4.
Follow Mucositis: new trials by email Literature Review of Mucositis trials Research Report on Mucositis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Methadone as an Alternative Treatment for Children Underdoing HSCT PCA plus methadone (Experimental), PCA Alone (SOC) - Leukemia, Aplastic Anemia | Phase 3 | Suspended | University of Texas Southwestern Medical Center | 60 | 2028-01-01 | 2025-10-23 |
| Music and VR Effects on Pain, Anxiety, and Fear During Oral Mucositis Care in Leukaemic Children Music intervention, Virtual reality - Anxiety, Pain | Not applicable | Not yet recruiting | Ege University | 45 | 2026-12-01 | 2026-05-19 |
| A Clinical Trial of the Administration of Light Therapy to Prevent Mouth Sores in Children With Cancer Photobiomodulation for prevention arm, Photobiomodulation for exploratory arm - Mucositis Oral | Not applicable | Not yet recruiting | Medical College of Wisconsin | 50 | 2026-11-01 | 2026-10-06 |
| Retrospective Observational Study of Oral Complications and Quality of Life in Head and Neck Cancer Patients Treated With Radiotherapy or Chemoradiotherapy. Oral Mucositis, Quality of Life | Not yet recruiting | Mucosa Innovations, S.L. | 60 | 2026-08-01 | 2026-07-31 | |
| Amimestrocel Injection for Preventing Severe Oral Mucositis in HSCT Patients Amimestrocel injection - Oral Mucositis, Stomatitis | Phase 2 | Recruiting | The First Affiliated Hospital of Soochow University | 22 | 2026-02-15 | 2026-04-14 |
| Effect of Water Flossing on Gingival Inflammation Around Single Implants Water flosser, Tooth brush and string floss - Peri Implant Mucositis | Not applicable | Not yet recruiting | King Abdulaziz University | 20 | 2026-01-01 | 2026-01-23 |
| The Effect Of Enamel Matrix Derivatives On Gingival Tissue Thickness Enamel Matrix Derivative - Dental Implantation, Missing Teeth | Not applicable | Recruiting | The University of Texas Health Science Center at San Antonio | 32 | 2025-08-31 | 2025-11-12 |
| Microbiome Modulation by PEMF on Plaque Induced Mucositis in Human Jaws PEMF abd Sham (control), Teeth wih gingivits - Microbial Colonization, Peri-Implantitis | Not applicable | Completed | Jamil awad shibli | 35 | 2025-05-11 | 2026-05-01 |
| Monitoring of Implant Diseases: Diagnosis and Monitoring With aMMP-8 Test Technology Peri-Implantitis and Peri-implant mucositis - Peri-Implant Health, Peri-Implantitis and Peri-implant Mucositis | Not applicable | Enrolling by invitation | Hanna Lahteenmaki | 50 | 2025-01-11 | 2025-03-06 |
| Effects of Enamel Matrix Derivative in the Treatment of Peri-implant Mucositis Placebo gel, Enamel Matrix Proteins Derivative - Mucositis, Peri Implant Mucositis | Not applicable | Enrolling by invitation | University of Catania | 54 | 2024-12-05 | 2025-06-04 |
| High Heated Humidity in Stem Cell Transplant Airvo, Standard of Care - Autologous Stem Cell Transplant | Phase 2 | Recruiting | AHS Cancer Control Alberta | 90 | 2024-11-05 | 2025-01-30 |
| Assessing Manual Acupuncture's Impact on Mucositis From Nasopharynx Cancer Radiotherapy: A Visual Analogue Scale (VAS) and Quality of Life Study Verum Acupuncture, Sham Acupuncture - Cancer, Nasopharyngeal Carcinoma | Not applicable | Unknown | Universitas Indonesia | 30 | 2024-07-01 | 2024-06-26 |
| Impact of an AI-Based Chatbot on Implant Patient Management: RCT AI Chatbot, Standard Oral Hygiene Education - Peri-Implant Mucositis, Peri-implantitis | Not applicable | Completed | University of Catania | 110 | 2024-06-01 | 2025-12-24 |
| RRx-001 for Reducing Oral Mucositis in Patients Receiving Chemotherapy and Radiation for Head and Neck Cancer RRx-001, Intensity Modulated Radiation Therapy (IMRT), Cisplatin for injection 100 mg/m2 - Oral Mucositis | Phase 2 | Active not recruiting | EpicentRx, Inc. | 216 | 2024-04-02 | 2026-06-26 |
| Management of Radiotherapy-related Xerostomia With Green Tea and Peppermint mix of (green tea and peppermint) - Radiation-induced Xerostomia | Not applicable | Unknown | Ain Shams University | 40 | 2024-04-01 | 2024-05-16 |
| Prevention of Oral Mucositis and Improvement of Quality of Life for Patients With Breast Cancer Undergoing Adjuvant Radiotherapy Alginos Oral Suspension - Breast Carcinoma | Phase 2 | Enrolling by invitation | Taipei City Hospital | 90 | 2024-02-15 | 2025-05-06 |
| Effect of Hawthorn Vinegar, Black Mulberry Syrup and Green Tea on Oral Mucositis Hawthorn Vinegar Group, Black Mulberry Syrup Group, Green Tea Group - Mucositis, Quality of Life | Not applicable | Completed | Karadeniz Technical University | 120 | 2024-02-06 | 2025-11-18 |
| Adjunctive Treatments for the Prevention of Radiotherapy-Induced Mucositis MEBO ointment, Symptomatic treatment only - Radiotherapy Side Effect, Mucositis | Not applicable | Completed | Beni-Suef University | 60 | 2024-01-01 | 2024-07-25 |
| Effect of Pentoxifylline on Preventing Chemotherapy-induced Toxicities in Patients With Breast Cancer Pentoxifylline 400mg plus chemotherapy, Chemotherapy - Breast Cancer Female, Breast Cancer Patients | Phase 2 | Completed | Mansoura University | 100 | 2023-12-25 | 2025-07-28 |
| Effect of Synbiotic Supplementation on the Prevention of Mucositis in Cancer Patients Undergoing Chemotherapy Symbiotic, Maltodextrin - Colo-rectal Cancer | Not applicable | Recruiting | Federal University of Minas Gerais | 80 | 2023-12-12 | 2024-08-29 |
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Head and Neck Neoplasms (46) · Stomatitis (43) · Neoplasms (21) · Xerostomia (15) · Pain (14) · Squamous Cell Carcinoma of Head and Neck (11) · Peri-Implantitis (9) · Multiple Myeloma (8) · Radiation Injuries (8) · Leukemia (7) · Ulcer (7) · Oral Ulcer (6) · Hematologic Neoplasms (5) · Lymphoma (5)
Digestive System Diseases (207) · Gastroenteritis (207) · Stomatognathic Diseases (207) · Gastrointestinal Diseases (206) · Mouth Diseases (206) · Neoplasms (82) · Neoplasms by Site (68) · Neoplasms by Histologic Type (42) · Pathological Conditions, Signs and Symptoms (42) · Hemic and Lymphatic Diseases (29) · Signs and Symptoms (28) · Hematologic Diseases (25) · Immune System Diseases (22) · Neoplasms, Glandular and Epithelial (19) · Neurologic Manifestations (19)
Radiotherapy (9) · Cisplatin (8) · Fibroblast Growth Factor 7 (7) · Low-Level Light Therapy (6) · Injections (4) · Ketamine (4) · Leucovorin (4) · Methotrexate (4) · Mouthwashes (4) · Probiotics (4) · Radiation (4) · Sodium Bicarbonate (4) · angiotensin I (1-7) (4) · Cryotherapy (3) · Drug Therapy (3)
Tarix Pharmaceuticals (4) · Ain Shams University (3) · M.D. Anderson Cancer Center (3) · Roswell Park Cancer Institute (3) · Swedish Orphan Biovitrum (3) · The University of Texas Health Science Center at San Antonio (3) · Tosk, Inc. (3) · Universidade Federal do Rio Grande do Norte (3) · University College, London (3) · Università Vita-Salute San Raffaele (3) · Vanderbilt-Ingram Cancer Center (3) · AHS Cancer Control Alberta (2) · Access Pharmaceuticals, Inc. (2) · Barbara Ann Karmanos Cancer Institute (2) · Beni-Suef University (2)
United States (69) · Italy (13) · Egypt (11) · France (9) · Spain (9) · Brazil (8) · Canada (8) · Iran (8) · China (7) · Israel (6) · Turkey (Türkiye) (6) · United Kingdom (6) · Denmark (5) · India (5) · Taiwan (4)
Anurag Singh (3) · Emile Youssef, MD, PhD (3) · Bruno CV Gurgel, Doctor (2) · Cesar O Freytes, MD (2) · Navin Khattry, MD, DM (2) · Nicole Blijlevens, MD PhD (2) · Aaron Cumpston, PharmD (1) · Abeer Abdulmaksoud, MD (1) · Abeer Saad, MD (1) · Adele K. Fielding (1) · Adrian S Dobs, MD MHS (1) · Albert Lie, Dr (1) · Alejandro De la Torre, MD (1) · Alicia Lozano, MD (1)
PMID 18973181, PMID 15057287, PMID 15777328, PMID 17053058, PMID 17760823, PMID 17896890, PMID 18468541, PMID 18724857, PMID 19081897, PMID 19634161, PMID 19885903, PMID 20937384, PMID 21109081, PMID 21547879, PMID 2179802, PMID 22092445, PMID 22167295, PMID 23095990, PMID 23176716, PMID 23292233, PMID 23379680, PMID 23909727, PMID 24733799, PMID 24877167, PMID 25123298, PMID 25151488, PMID 25495683, PMID 27480385, PMID 28075506, PMID 28150872, PMID 28190158, PMID 29392234, PMID 29734184, PMID 29926952, PMID 30046225, PMID 30557088, PMID 30718802, PMID 31101577, PMID 31405750, PMID 31448214, PMID 32676853, PMID 32700140, PMID 32764436, PMID 32786044, PMID 32790844, PMID 33225965, PMID 33580845, PMID 33660192, PMID 33774891, PMID 34193407
P30CA022453 (2), U10CA095861 (2), 1UG3DE030401-01 (1), 2009 (1), 2018 (1), K23DE016946 (1), K24AI001610 (1), P30CA006516 (1), P30CA015083 (1), P30CA068485 (1), P30CA072720 (1), R21CA158530 (1), U10CA037404 (1)