8 completed, 3 unknown, 2 recruiting, 2 withdrawn. 16 Phase 1, 6 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 16 | Completed 8, Unknown 3, Recruiting 2, Withdrawn 2, Terminated 1 |
| Phase 2 | 6 | Completed 3, Withdrawn 2, Recruiting 1 |
Follow Mitral Valve Insufficiency: new trials by email Literature Review of Mitral Valve Insufficiency trials Research Report on Mitral Valve Insufficiency
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The REValve Clinical Trial an Evaluation Of the ReValve Palmetto Valve for the Replacement of the Native Mitral VaLVE ReValve System - Mitral Regurgitation | Phase 1 | Recruiting | ReValve Solutions Inc. | 20 | 2026-09-01 | 2026-09-29 |
| Effect of Anesthetics on Troponin I and С-reactive Protein Propofol, Isoflurane, Sevoflurane - Mitral Valve Insufficiency, Aortic Valve Insufficiency | Phase 1 | Completed | Astana Medical University | 255 | 2021-11-30 | 2023-06-05 |
| The Effects of Sevoflurane, Isoflurane and Propofol During Cardiac Surgery Propofol, Isoflurane, Sevoflurane - Coronary Artery Disease, Mitral Valve Insufficiency | Phase 1 | Completed | Astana Medical University | 89 | 2021-01-22 | 2023-01-25 |
| Use of Phenylephrine for Assessment of Mitral Regurgitation Severity Mydfrin - Mitral Regurgitation | Phase 1 / Phase 2 | Recruiting | Montefiore Medical Center | 35 | 2020-12-01 | 2025-07-20 |
| Neochordae Technique in Mitral Valve Repair adjustable neochordae Technique - Mitral Valve Prolapse, Mitral Regurgitation | Phase 1 | Unknown | National Heart Institute, Egypt | 30 | 2020-03-02 | 2020-03-09 |
| Atrial Functional Mitral Regurgitation Response In Mitral Loop Cerclage Annuloplasty (AFRICA Study) Mitral Loop Cerclage Annuloplasty - Atrial Functional Mitral Regurgitation, Heart Failure | Phase 1 / Phase 2 | Completed | Tau-MEDICAL Co., Ltd. | 1 | 2018-04-02 | 2021-04-26 |
| CardiAQ-Edwards™ Transcatheter Mitral Valve Replacement (TMVR) Study Transcatheter Mitral Valve Re-placement (TMVR) with the CardiAQ-Edwards™ Transcatheter Mitral Valve - Mitral Valve Regurgitation | Phase 1 / Phase 2 | Withdrawn | Edwards Lifesciences | 2016-11-01 | 2018-01-09 | |
| St. Jude Medical Percutaneous Mitral Valve Repair Study PMVr procedure (SJM Percutaneous Mitral Valve Repair (PMVr) - Mitral Valve Prolapse | Phase 1 | Completed | Abbott Medical Devices | 2 | 2011-12-01 | 2019-02-04 |
| Mitral Insufficiency Reduction With Biventricular Pacing CRT pacing - Mitral Regurgitation | Phase 1 | Unknown | Trinity Medical Center, Illinois | 50 | 2011-01-01 | 2010-12-02 |
| Medical Versus Surgical Management of Moderate Mitral Regurgitation Following Percutaneous Coronary Intervention surgical mitral valve repair w/ mitral valve annuloplasty - Myocardial Infarction, Mitral Regurgitation | Phase 1 / Phase 2 | Withdrawn | Southern Illinois University | 2010-07-01 | 2014-06-16 | |
| VIVID - Valvular and Ventricular Improvement Via iCoapsys Delivery - Feasibility Study Percutaneous mitral valve repair - Mitral Valve Regurgitation, Left Ventricular Dysfunction | Phase 1 | Unknown | Myocor | 30 | 2008-01-01 | 2009-06-24 |
| Using Beta Blockers to Treat Mitral Regurgitation Beta-blocker therapy (TOPROL-XL® ) - Heart Disease, Mitral Regurgitation | Phase 1 | Terminated | Wake Forest University Health Sciences | 27 | 2007-10-01 | 2018-08-14 |
| Aachen Safety and Efficacy of the Percutaneous Transvenous Mitral Annuloplasty Device to Reduce Mitral Regurgitation PTMA Implant - Heart Failure, Mitral Regurgitation | Phase 1 / Phase 2 | Completed | Viacor | 4 | 2007-02-01 | 2008-11-06 |
| Safety and Efficacy of the Percutaneous Transvenous Mitral Annuloplasty Device to Reduce Mitral Regurgitation PTMA (Percutaneous Transvenous Mitral Annuloplasty) Implant - Heart Failure, Mitral Regurgitation | Phase 1 | Completed | Viacor | 12 | 2006-04-01 | 2008-11-06 |
| Montreal Safety and Efficacy of the Percutaneous Transvenous Mitral Annuloplasty Device PTMA (Percutaneous Transvenous Mitral Annuloplasty) Implant - Heart Failure, Mitral Regurgitation | Phase 1 | Completed | Viacor | 5 | 2006-04-01 | 2008-11-06 |
| Feasibility Study of a Percutaneous Mitral Valve Repair System. Percutaneous mitral valve repair (MitraClip Implant) - Mitral Valve Insufficiency, Mitral Valve Regurgitation | Phase 1 / Phase 2 | Completed | Abbott Medical Devices | 55 | 2003-07-01 | 2018-11-07 |
Heart Failure (6) · Mitral Valve Prolapse (3) · Aortic Valve Insufficiency (2) · Coronary Artery Disease (2) · Heart Diseases (2) · Myocardial Infarction (2) · Atrial Fibrillation (1) · Gastroesophageal Reflux (1) · Heart Valve Diseases (1) · Lymphoma, Follicular (1) · Myocardial Ischemia (1) · Neoplasm Metastasis (1) · Ventricular Dysfunction, Left (1)
Cardiovascular Diseases (16) · Heart Valve Diseases (15) · Heart Diseases (14) · Pathologic Processes (4) · Pathological Conditions, Signs and Symptoms (4) · Vascular Diseases (4) · Heart Valve Prolapse (3) · Myocardial Ischemia (3) · Aortic Valve Disease (2) · Arterial Occlusive Diseases (2) · Arteriosclerosis (2) · Coronary Disease (2) · Infarction (2) · Ischemia (2) · Necrosis (2)
Isoflurane (2) · Mutagenesis, Insertional (2) · Propofol (2) · Sevoflurane (2) · Adrenergic beta-Antagonists (1) · Metoprolol (1) · Mitral Valve Annuloplasty (1) · Oxymetazoline (1) · Phenylephrine (1)
Viacor (3) · Abbott Medical Devices (2) · Astana Medical University (2) · Edwards Lifesciences (1) · Montefiore Medical Center (1) · Myocor (1) · National Heart Institute, Egypt (1) · ReValve Solutions Inc. (1) · Southern Illinois University (1) · Tau-MEDICAL Co., Ltd. (1) · Trinity Medical Center, Illinois (1) · Wake Forest University Health Sciences (1)
United States (5) · Germany (3) · Canada (2) · Kazakhstan (2) · Denmark (1) · Egypt (1) · France (1) · Georgia (1) · Italy (1) · Netherlands (1) · South Korea (1) · Switzerland (1) · United Kingdom (1)
Alibek Kh Mustafin, Professor (2) · Adam A Berman, MD (1) · Amr Zaher, M.D. (1) · Christina Vassileva, M.D. (1) · Helbert Acosta, MD (1) · Jagmeet Singh, MD (1) · Lars Sondergaard (1) · Luc Bilodeau, MD (1) · Mario Garcia, MD (1) · Min Pu, MD (1) · Patrick Hranitzky, MD (1) · Rainer Hoffmann, MD (1) · Stefan Sack, MD (1) · Ted Feldman, M.D. (1) · Yong-Hyun Park, MD, PhD (1)
PMID 17543250, PMID 19329766, PMID 19679246, PMID 21422390, PMID 21492763, PMID 23580745, PMID 23633132