14 completed, 6 unknown, 5 active not recruiting, 3 terminated. 31 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 31 | Completed 14, Unknown 6, Active not recruiting 5, Terminated 3, Recruiting 2, Not yet recruiting 1 |
Follow Left Ventricular Dysfunction: new trials by email Literature Review of Left Ventricular Dysfunction trials Research Report on Left Ventricular Dysfunction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Monitoring for CardioToxicity Using WeArable deVices While Undergoing cancEr Treatments (MCT-WAVE) Mobile Cardiac Telemetry, Wearable Cardiac Monitor - Cardiotoxicity, Cancer | Not applicable | Not yet recruiting | University of Minnesota | 72 | 2026-12-01 | 2026-11-02 |
| The JenaValve ALIGN-AR LVAD Registry JenaValve Trilogy Heart Valve System - Aortic Regurgitation, Aortic Valve Insufficiency | Not applicable | Active not recruiting | JenaValve Technology, Inc. | 50 | 2024-12-09 | 2026-10-29 |
| Left Bundle Branch Pacing on Outcomes and Ventricular Remodeling in Biventricular CRT Nonresponders Cardiac Resynchronization Therapy Devices with Defibrillator Function (CRT-D) or CRT-D Leads Replacement, CRT-D or CRT-D Leads Replacement with New Lead Implantation to Left Bundle Branch and Inactivation of Conventional Right and Left Ventricular Pacing, CRT-D or CRT-D Leads Replacement with New Lead Implantation to Left Bundle Branch and Inactivation of Conventional Right Ventricular Pacing - Heart Failure, Left Bundle-Branch Block | Not applicable | Recruiting | Tomsk National Research Medical Center of the Russian Academy of Sciences | 30 | 2024-11-01 | 2024-11-22 |
| Reducing Cognitive Impairment by Management of Heart Failure as a Modifiable Risk Factor Disease management program - Heart Failure, Cognitive Impairment | Not applicable | Unknown | Baker Heart and Diabetes Institute | 168 | 2024-07-01 | 2024-08-12 |
| Microvascular Dysfunction Assessment to Predict Left Ventricular Reverse Remodeling Thermodilution based assessment of coronary microcirculation - Heart Failure, Left Ventricular Dysfunction | Not applicable | Active not recruiting | Azienda Ospedaliera Universitaria Integrata Verona | 200 | 2024-01-03 | 2026-10-28 |
| Conventional Biventricular Versus Left Bundle Branch Pacing on Outcomes in Heart Failure Patients Implantation of Cardioverter-defibrillator with a Resynchronization Function Using Biventricular Pacing, Implantation of Cardioverter-defibrillator with a Resynchronization Function Using Left Bundle Branch Pacing - Heart Failure, Left Bundle-Branch Block | Not applicable | Recruiting | Tomsk National Research Medical Center of the Russian Academy of Sciences | 60 | 2023-10-01 | 2025-09-10 |
| IMpella-Protected cArdiaC Surgery Trial (IMPACT) Impella 5.5 with SmartAssist - Left Ventricular Dysfunction | Not applicable | Completed | Abiomed Inc. | 100 | 2023-09-21 | 2026-08-28 |
| IMPACT EU Post-Market Clinical Follow-Up Study Device: Impella 5.5 with SmartAssist - Left Ventricular Dysfunction | Not applicable | Active not recruiting | Abiomed Inc. | 123 | 2023-04-27 | 2025-09-30 |
| Sodium Lowering Vascular Effects Trial Sodium Reduction Intervention - Endothelial Dysfunction, Vascular Stiffness | Not applicable | Active not recruiting | Tulane University | 256 | 2023-01-25 | 2026-10-01 |
| Evaluation of the BIOTRONIK AutoAdapt Algorithm for Continuous Automatic Adaptive Cardiac Resynchronization Echo-based assessment of the acute hemodynamic effect of the CRT AutoAdapt feature., Echocardiography AV optimization, Echocardiography - Heart Failure, Cardiac Arrhythmia | Not applicable | Completed | Biotronik SE & Co. KG | 198 | 2021-08-31 | 2025-09-18 |
| HIS-Purkinje Conduction System Pacing Optimized Trial of Cardiac Resynchronization Therapy HOT-CRT, Biventricular Pacing - Heart Failure，Congestive, Cardiomyopathies | Not applicable | Completed | Pugazhendhi Vijayaraman | 100 | 2021-04-15 | 2024-08-07 |
| Impella®-Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function Impella CP® / Impella CP® with SmartAssist® / Impella 2.5®, IABP Intra-aortic balloon pump - Left Ventricular Dysfunction, Coronary Artery Disease | Not applicable | Active not recruiting | Abiomed Inc. | 1252 | 2021-04-13 | 2026-07-28 |
| Landiolol for Rate Control in Decompensated Heart Failure Due to Atrial Fibrillation Intensive heart rate control with landiolol, Standard approach to heart rate control - Atrial Fibrillation, Atrial Fibrillation Rapid | Not applicable | Unknown | Institute for Clinical and Experimental Medicine | 40 | 2020-11-05 | 2021-01-06 |
| Effects of Home-based Exercise Rehabilitation on Healthcare Utilization in HeartMate 3 Patients Home-based Exercise Rehabilitation., Usual Care - Heart Failure, Left Ventricular Dysfunction | Not applicable | Completed | University of Rochester | 20 | 2020-10-19 | 2023-11-08 |
| Ivabradine in Cirrhotic Cardiomyopathy Betablocker + ivabradine, Betablocker - Cirrhotic Cardiomyopathy, Left Ventricular Dysfunction | Not applicable | Unknown | Post Graduate Institute of Medical Education and Research, Chandigarh | 130 | 2020-01-01 | 2024-02-13 |
| Correlations Between Oxidative Stress Biomarkers, h-FABP and Left Ventricular Dysfunction in Patients With Acute Myocardial Infarction Undergoing Primary PCI Dosing Oxidative stress biomarkers & hFABP in STEMI pPCI patients - STEMI, Oxidative Stress | Not applicable | Unknown | Grigore T. Popa University of Medicine and Pharmacy | 200 | 2019-08-01 | 2019-07-30 |
| Efficacy of Cardio-Oncology Rehabilitation Exercise for Women With Breast Cancer and Treatment Related Cardiotoxicity Exercise Rehabilitation - Breast Cancer, Left Ventricular Dysfunction | Not applicable | Terminated | University Health Network, Toronto | 2 | 2018-04-01 | 2018-10-12 |
| Strategic Management to Improve CRT Using Multi-Site Pacing Post Approval Study (Reference # C1918) CRT-D - Left Ventricular Dysfunction | Not applicable | Completed | Boston Scientific Corporation | 586 | 2018-01-05 | 2022-01-03 |
| Reprogramming to Prevent Progressive Pacemaker-induced Remodelling Personalised programming - Left Ventricular Dysfunction, Heart Failure, Systolic | Not applicable | Completed | University of Leeds | 91 | 2017-08-01 | 2019-09-26 |
| Rate RESPONSIVe Pacing in Patients With Permanent AF Underwent AV Node ABLation and bivEntricular Pacing (RESPONSIBLE) Rate Response on first (VVI biventricular pacing), Rate Response off first (VVI biventricular pacing) - Left Ventricular Dysfunction, Atrial Fibrillation | Not applicable | Completed | Azienda Ospedaliera Cardinale G. Panico | 60 | 2015-01-01 | 2015-11-30 |
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Ventricular Dysfunction, Left (31) · Heart Failure (12) · Coronary Artery Disease (4) · Atrial Fibrillation (3) · Arrhythmias, Cardiac (2) · Breast Neoplasms (2) · Bundle-Branch Block (2) · Cardiovascular Diseases (2) · Heart Failure, Systolic (2) · Motor Activity (2) · Myocardial Infarction (2) · Ventricular Remodeling (2) · Anterior Wall Myocardial Infarction (1) · Aortic Valve Disease (1) · Aortic Valve Insufficiency (1)
Ventricular Dysfunction (31) · Heart Diseases (30) · Cardiovascular Diseases (29) · Pathological Conditions, Signs and Symptoms (15) · Pathologic Processes (14) · Arrhythmias, Cardiac (7) · Vascular Diseases (7) · Myocardial Ischemia (5) · Arterial Occlusive Diseases (4) · Arteriosclerosis (4) · Cardiac Conduction System Disease (4) · Coronary Disease (4) · Infarction (3) · Ischemia (3) · Necrosis (3)
Cardiac Resynchronization Therapy (1) · Cardiac Resynchronization Therapy Devices (1) · Colloids (1) · Defibrillators (1) · Defibrillators, Implantable (1) · Dobutamine (1) · Exercise Therapy (1) · Fatty Acid Binding Protein 3 (1) · Intra-Aortic Balloon Pumping (1) · Ivabradine (1) · Mass Screening (1) · Simendan (1) · landiolol (1)
Abiomed Inc. (3) · University Health Network, Toronto (3) · Abbott Medical Devices (2) · Tomsk National Research Medical Center of the Russian Academy of Sciences (2) · Azienda Ospedaliera Cardinale G. Panico (1) · Azienda Ospedaliera Universitaria Integrata Verona (1) · Baker Heart and Diabetes Institute (1) · Biotronik SE & Co. KG (1) · Boston Scientific Corporation (1) · British Cardiovascular Intervention Society (1) · Grigore T. Popa University of Medicine and Pharmacy (1) · Institute for Clinical and Experimental Medicine (1) · JenaValve Technology, Inc. (1) · Medtronic Cardiac Rhythm and Heart Failure (1) · Post Graduate Institute of Medical Education and Research, Chandigarh (1)
United States (11) · Canada (4) · United Kingdom (4) · Czechia (3) · Germany (3) · Italy (3) · Australia (2) · Netherlands (2) · Russia (2) · Switzerland (2) · Denmark (1) · India (1) · Ireland (1) · New Zealand (1) · Romania (1)
Roman E Batalov, M.D. (2) · Tariel A Atabekov, Ph.D. (2) · Adil Bashir, PhD (1) · Adrian Covic, Professor (1) · Alan Kadish, MD (1) · Christina Eintrei, Professon (1) · Daniel Goldstein, MD (1) · Divaka Perera, MRCP, MD (1) · Dr. Gerald Kaye (1) · Edward Soltesz, MD (1) · Gabriel Sayer, MD (1) · Hermann Reichenspurner, MD, PhD (1) · Hermann Reichenspurner, Prof. Dr. Dr. (1) · Karl-Heinz Kuck, Prof. Dr. (1)
PMID 19958856, PMID 20109864, PMID 20736470, PMID 21840055, PMID 23224207, PMID 23821090, PMID 25181050, PMID 25189602, PMID 25666325, PMID 25862716, PMID 26139583, PMID 26517949, PMID 31305281, PMID 31342529, PMID 33579197, PMID 34586748, PMID 34898655, PMID 35068798, PMID 35436135, PMID 37715742, PMID 40315243, PMID 41761704, PMID 41895564