33 completed, 16 unknown, 6 terminated, 4 recruiting. 20 Not applicable, 16 Phase 2, 14 Phase 4, 9 Phase 3, 5 Phase 1.
Follow Dobutamine: new trials by email Literature Review of Dobutamine trials Research Report on Dobutamine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The PROTECT-HIE Pilot Trial Dobutamine, TnECHO - Hypoxic-ischemic Encephalopathy (HIE) | Phase 2 | Recruiting | University of Alberta | 40 | 2026-10-13 | 2026-11-05 |
| Dobutamine During Major Abdominal Surgery Dobutamine, Routine care - Intraoperative Myocardial Depression | Not applicable | Completed | University of Hamburg-Eppendorf | 100 | 2025-06-16 | 2026-04-29 |
| Dobutamine for Management of Surgical Patients With Septic Shock Dobutamine, Norepinephrine - Patients With Septic Shock, Surgical Patients | Not applicable | Completed | First Affiliated Hospital of Zhejiang University | 584 | 2024-06-18 | 2025-12-04 |
| Haemodynamic Effects of Dobutamine in Patients With Wild-type Transthyretin Amyloid Cardiomyopathy (ATTRwt) Dobutrex - ATTR Amyloidosis Wild Type | Phase 1 / Phase 2 | Recruiting | Steen Hvitfeldt Poulsen | 15 | 2024-04-08 | 2026-06-01 |
| Effect of TEE-guided Non-fluid Limited Combined With Dobutamine on Hepatic Venous Blood Flow Spectrum Dobutamine hydrochloride, Injectable, 0.9% normal saline - Laparoscopic Hepatectomy | Early Phase 1 | Unknown | Sichuan University | 51 | 2024-02-01 | 2024-01-18 |
| Use of Dobutamine in Patients With Sepsis and Maintained Hypoperfusion After Initial Volemic Resuscitation. Dobutamine - Sepsis, Hypoperfusion | Phase 2 | Unknown | Federal University of São Paulo | 120 | 2024-02-01 | 2024-01-30 |
| Dobutamine Versus Milrinone in Management of Critically Ill Low Cardiac Output Pediatric Patients at Cairo University Children's Hospital Dobutamine - Dobutamine, Milrinone , Pediatrics , Low Cardiac Output | Not applicable | Unknown | Cairo University | 40 | 2023-10-01 | 2023-08-21 |
| Consistency of Carotid Doppler Blood Flow and Thermodilution Technique passive leg raising, Dobutamine - Cardiac Surgery | Not applicable | Recruiting | Shanghai Zhongshan Hospital | 200 | 2023-05-31 | 2023-07-13 |
| Novel Echocardiographic and Invasive Haemodynamic Measurements in the Assessment of Patients Low Flow Low Gradient Aortic Stenosis Undergoing TAVI Ultrasound, Catheters, Soft study wire - Cardiovascular Abnormalities | Not applicable | Completed | The Royal Wolverhampton Hospitals NHS Trust | 7 | 2022-07-01 | 2025-01-06 |
| Ivabradine Effects in Cardiogenic Shock Requiring Inotropic Support Ivabradine 7.5Mg Tab, DOBUTamine Injectable Solution - Heart Failure, Cardiogenic Shock | Phase 3 | Unknown | The Young Investigator Group of Cardiovascular Research | 200 | 2022-07-01 | 2022-10-26 |
| Clinical Outcomes of Levosimendan Versus Dobutamine Versus Milrinone in Cases With Acute Decompensated Heart Failure With Impaired Renal Function Levosimendan, Dobutamine, Milrinone - Acute Decompensated Heart Failure (ADHF), Cardiorenal Syndrome (CRS) | Phase 4 | Completed | Ain Shams University | 60 | 2022-06-01 | 2026-09-21 |
| Low-Dose Dobutamine and Single-Dose Tocilizumab in Acute Myocardial Infarction With High Risk of Cardiogenic Shock Tocilizumab, Dobutamine, NaCl 0.9% - Acute Myocardial Infarction, Cardiogenic Shock | Phase 2 | Active not recruiting | Copenhagen University Hospital, Rigshospitalet | 100 | 2022-03-13 | 2025-07-17 |
| CAPITAL DOREMI 2: Inotrope Versus Placebo Therapy for Cardiogenic Shock Dobutamine, Milrinone, Normal Saline - Shock, Cardiogenic | Phase 4 | Recruiting | Ottawa Heart Institute Research Corporation | 346 | 2022-03-05 | 2026-05-01 |
| Objective Confirmation of thе Anti-ischemic Effectiveness of Trimetazidine 80mg Once Daily in Patients With Stable Angina Who Had a History of Myocardial Infarction (METHOD) speckle tracking mode of the stress ECHO test with dobutamine - Coronary Artery Disease | Completed | Servier Russia | 36 | 2022-03-03 | 2024-04-18 | |
| Supernormal Oxygen Delivery for Patients With Severe Burns Dobutamine - Burn Surgery, Dobutamine | Early Phase 1 | Unknown | Guangzhou Red Cross Hospital | 100 | 2022-02-28 | 2022-02-16 |
| Effect of Dobutamine on Hepatic Blood Flow During Goal-directed Hemodynamic Therapy Dobutamine Hydrochloride - General Anesthesia | Phase 4 | Completed | University Hospital, Ghent | 58 | 2021-09-14 | 2023-08-01 |
| Adjunctive DobutAmine in sePtic Cardiomyopathy With Tissue Hypoperfusion Placebos, Dobutamine - Sepsis, Cardiomyopathies | Phase 3 | Completed | University Hospital, Limoges | 136 | 2020-09-20 | 2025-11-21 |
| Dobutamine on the Cardiac Conduction System Dobutamine - Arrhythmias, Cardiac | Early Phase 1 | Completed | Northwell Health | 37 | 2020-01-14 | 2022-01-26 |
| Improving Tissue Oxygenation in Breast Reconstruction Surgery Dobutamine - Perioperative Tissue Oxygenation | Phase 1 / Phase 2 | Completed | Dr. Glenio Mizubuti (MD, PhD) | 40 | 2019-07-12 | 2025-08-05 |
| Influence of Continuous Administration of Phenylephrine Versus Dobutamine on Spinal Oxygen Saturation, Measured With Near-infrared Spectroscopy (NIRS). Phenylephrine, Dobutamine - Nfuence of Vasoactive Medication on Spinal Oxygenation | Phase 4 | Completed | University Hospital, Ghent | 36 | 2019-07-04 | 2022-12-12 |
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Heart Failure (9) · Sepsis (7) · Shock, Cardiogenic (6) · Shock (5) · Shock, Septic (5) · Coronary Artery Disease (4) · Cardio-Renal Syndrome (3) · Cardiovascular Diseases (3) · Hypotension (3) · Myocardial Ischemia (3) · Acute Kidney Injury (2) · Cardiac Output, Low (2) · Coronary Disease (2) · Femoral Fractures (2) · Hypoxia-Ischemia, Brain (2)
Ottawa Heart Institute Research Corporation (2) · University Hospital, Ghent (2) · University Hospital, Grenoble (2) · Abbott (1) · Adelina Pellicer (1) · Ain Shams University (1) · Azienda Policlinico Umberto I (1) · Brighton and Sussex University Hospitals NHS Trust (1) · Cairo University (1) · Cambridge University Hospitals NHS Foundation Trust (1) · Central Hospital, Nancy, France (1) · Chulalongkorn University (1) · Competence Network for Congenital Heart Defects (1) · Copenhagen University Hospital, Rigshospitalet (1) · Dr. Glenio Mizubuti (MD, PhD) (1)
United States (12) · France (6) · Germany (6) · China (5) · United Kingdom (5) · Canada (4) · Denmark (4) · Belgium (3) · Egypt (3) · Italy (3) · Sweden (3) · Spain (2) · Australia (1) · Brazil (1) · Chile (1)
Adelina Pellicer, MD PhD (1) · Alina Bergholz, MD (1) · Amalia Pinguello, MD (1) · Anand Chockalingam, MD (1) · Andrea Morelli, M.D. (1) · Ayse Baysal, MD (1) · Benjamin M Hibbert, MD, PhD (1) · Bruce Goldner, MD (1) · Caroline Vanpeteghem, MD (1) · Charles Phillips, M.D. (1) · Christina Eintrei, Professon (1) · Djillali Annane, MD, PhD (1) · Dov Freimark, Prof. MD. (1) · Eric Bellissant, MD, PhD (1) · Erik Sloth, Professor (1)
PMID 10716477, PMID 10889132, PMID 10892758, PMID 10987591, PMID 11190460, PMID 12135124, PMID 12407803, PMID 12520560, PMID 12868353, PMID 15497198, PMID 15519198, PMID 15769768, PMID 1579757, PMID 16376782, PMID 16461840, PMID 16464911, PMID 16980115, PMID 17331245, PMID 17377079, PMID 17473298, PMID 17720019, PMID 17982163, PMID 17982182, PMID 18036459, PMID 18279773, PMID 19001473, PMID 19114878, PMID 19539144, PMID 19717846, PMID 20156348, PMID 20359842, PMID 21182783, PMID 21546269, PMID 21670242, PMID 21935715, PMID 22064593, PMID 22429630, PMID 22929242, PMID 22995877, PMID 23067578, PMID 23837606, PMID 23996286, PMID 24291279, PMID 24329122, PMID 24438712, PMID 25032942, PMID 25173339, PMID 26116470, PMID 26290421, PMID 26794722
2009 (2), 2008 (1), 2017 (1), 2023 (1), K23HL071562 (1), R21HL106103 (1)