51 completed, 17 unknown, 9 active not recruiting, 8 recruiting. 31 Not applicable, 7 Phase 2, 7 Phase 3, 5 Phase 4, 4 Phase 1.
Follow Left Ventricular Dysfunction: new trials by email Literature Review of Left Ventricular Dysfunction trials Research Report on Left Ventricular Dysfunction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Monitoring for CardioToxicity Using WeArable deVices While Undergoing cancEr Treatments (MCT-WAVE) Mobile Cardiac Telemetry, Wearable Cardiac Monitor - Cardiotoxicity, Cancer | Not applicable | Not yet recruiting | University of Minnesota | 72 | 2026-10-29 | 2026-10-06 |
| Menopausal Hormone Therapy And Left Ventricular Function Menopausal Hormone Therapy - Menopause, Left Ventricular Dysfunction | Recruiting | Mayo Clinic | 50 | 2026-08-26 | 2026-08-27 | |
| PASCAL Precision-GDMT Registry Tricuspid Insufficiency, Tricuspid Regurgitation (TR) | Not yet recruiting | Ceric Sàrl | 50 | 2026-08-01 | 2026-05-13 | |
| Assement of Left Ventricular Function Before Decannulation in Cardiac Surgery :Visual Estimation vs TEE Intraoperative Left Ventricular Function Assessment - Cardiopulmonary Bypass Surgery, Left Ventricular Dysfunction | Recruiting | Ataturk University | 70 | 2026-01-01 | 2026-09-04 | |
| Preoperative Maltodextrin's Effect on Cardiac Function in Cardiac Surgery Maltodextrin solution, Placebo solution - Left Ventricular Dysfunction, Quality of Recovery | Phase 4 | Not yet recruiting | Jewish General Hospital | 70 | 2025-12-01 | 2025-02-24 |
| The JenaValve ALIGN-AR LVAD Registry JenaValve Trilogy Heart Valve System - Aortic Regurgitation, Aortic Valve Insufficiency | Not applicable | Active not recruiting | JenaValve Technology, Inc. | 50 | 2024-12-09 | 2026-10-26 |
| UC-MSC Transplantation for Left Ventricular Dysfunction After AMI UC-MSC, Control Group - Left Ventricular Dysfunction, Acute Myocardial Infarction | Phase 1 | Withdrawn | Shanghai Life Science & Technology | 2024-12-01 | 2026-05-11 | |
| Left Bundle Branch Pacing on Outcomes and Ventricular Remodeling in Biventricular CRT Nonresponders Cardiac Resynchronization Therapy Devices with Defibrillator Function (CRT-D) or CRT-D Leads Replacement, CRT-D or CRT-D Leads Replacement with New Lead Implantation to Left Bundle Branch and Inactivation of Conventional Right and Left Ventricular Pacing, CRT-D or CRT-D Leads Replacement with New Lead Implantation to Left Bundle Branch and Inactivation of Conventional Right Ventricular Pacing - Heart Failure, Left Bundle-Branch Block | Not applicable | Recruiting | Tomsk National Research Medical Center of the Russian Academy of Sciences | 30 | 2024-11-01 | 2024-11-22 |
| Reducing Cognitive Impairment by Management of Heart Failure as a Modifiable Risk Factor Disease management program - Heart Failure, Cognitive Impairment | Not applicable | Unknown | Baker Heart and Diabetes Institute | 168 | 2024-07-01 | 2024-08-12 |
| Pharmacokinetics of Inhaled Levosimendan Levosimendan 2.5 milligram/milliliter Injectable Solutiondose Inhaled, Levosimendan 2.5 milligram/milliliter Injectable Solutiondose Intravenous - Left Ventricular Dysfunction | Phase 2 | Unknown | Universitair Ziekenhuis Brussel | 6 | 2024-02-01 | 2024-05-20 |
| Microvascular Dysfunction Assessment to Predict Left Ventricular Reverse Remodeling Thermodilution based assessment of coronary microcirculation - Heart Failure, Left Ventricular Dysfunction | Not applicable | Active not recruiting | Azienda Ospedaliera Universitaria Integrata Verona | 200 | 2024-01-03 | 2026-10-28 |
| Conventional Biventricular Versus Left Bundle Branch Pacing on Outcomes in Heart Failure Patients Implantation of Cardioverter-defibrillator with a Resynchronization Function Using Biventricular Pacing, Implantation of Cardioverter-defibrillator with a Resynchronization Function Using Left Bundle Branch Pacing - Heart Failure, Left Bundle-Branch Block | Not applicable | Recruiting | Tomsk National Research Medical Center of the Russian Academy of Sciences | 60 | 2023-10-01 | 2025-09-10 |
| IMpella-Protected cArdiaC Surgery Trial (IMPACT) Impella 5.5 with SmartAssist - Left Ventricular Dysfunction | Not applicable | Completed | Abiomed Inc. | 100 | 2023-09-21 | 2026-08-28 |
| HIDRAdenitis Suppurativa and HEART Disease Hidradenitis, Hidradenitis Suppurativa | Active not recruiting | Herlev and Gentofte Hospital | 250 | 2023-08-01 | 2025-08-01 | |
| DAPAgliflozine to Attenuate Cardiac RemOdeling afTEr aCuTe myOcardial Infarction Dapagliflozin propanediol (FORXIGA™/FARXIGA™1), Placebo comparator - AMI, STEMI | Phase 3 | Recruiting | Assistance Publique - Hôpitaux de Paris | 450 | 2023-06-12 | 2025-12-19 |
| Acute Cardiac Dysfunction in Critical Illnes Echocardiography, Cardiac magnetic resonance imaging, Coronary CT - Multi Organ Failure, Left Ventricular Dysfunction | Unknown | Sahlgrenska University Hospital | 592 | 2023-05-29 | 2023-10-06 | |
| IMPACT EU Post-Market Clinical Follow-Up Study Device: Impella 5.5 with SmartAssist - Left Ventricular Dysfunction | Not applicable | Active not recruiting | Abiomed Inc. | 123 | 2023-04-27 | 2025-09-30 |
| London Valvular Heart Disease and Reduced Ejection Fraction Detection in a Multi-ethnic Community Using Cardiac Ultrasound Echocardiogram - Heart Valve Diseases, Left Ventricular Dysfunction | Recruiting | Queen Mary University of London | 500 | 2023-03-14 | 2026-02-23 | |
| Effects of Intrathecal Local Anesthetics on Left Ventricular Global Longitudinal Strain Intrathecal local anesthesia - Left Ventricular Dysfunction, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use | Completed | Milton S. Hershey Medical Center | 10 | 2023-02-01 | 2023-11-24 | |
| Sodium Lowering Vascular Effects Trial Sodium Reduction Intervention - Endothelial Dysfunction, Vascular Stiffness | Not applicable | Active not recruiting | Tulane University | 256 | 2023-01-25 | 2026-10-01 |
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Ventricular Dysfunction, Left (96) · Heart Failure (33) · Heart Diseases (10) · Myocardial Infarction (9) · Cardiovascular Diseases (8) · Coronary Artery Disease (7) · Ventricular Dysfunction, Right (7) · Heart Failure, Systolic (6) · COVID-19 (4) · Cardiotoxicity (4) · Myocardial Ischemia (4) · Ventricular Remodeling (4) · Acute Coronary Syndrome (3) · Arrhythmias, Cardiac (3) · Atrial Fibrillation (3)
Ventricular Dysfunction (93) · Cardiovascular Diseases (88) · Heart Diseases (86) · Pathological Conditions, Signs and Symptoms (40) · Pathologic Processes (37) · Vascular Diseases (28) · Myocardial Ischemia (18) · Infarction (13) · Ischemia (13) · Necrosis (13) · Arrhythmias, Cardiac (9) · Respiratory Tract Diseases (8) · Arterial Occlusive Diseases (7) · Arteriosclerosis (7) · Coronary Disease (7)
Echocardiography (7) · Intra-Aortic Balloon Pumping (2) · Serum Albumin, Human (2) · Simendan (2) · Anesthesia, Spinal (1) · Angptl4 protein, mouse (1) · Cardiac Resynchronization Therapy (1) · Cardiac Resynchronization Therapy Devices (1) · Caves (1) · Colloids (1) · Control Groups (1) · Defibrillators (1) · Defibrillators, Implantable (1) · Dobutamine (1) · Echocardiography, Transesophageal (1)
Eko Devices, Inc. (4) · Abiomed Inc. (3) · Herlev and Gentofte Hospital (3) · Sahlgrenska University Hospital (3) · The University of Texas Health Science Center, Houston (3) · University Health Network, Toronto (3) · Abbott Medical Devices (2) · Mayo Clinic (2) · Myocor (2) · Tomsk National Research Medical Center of the Russian Academy of Sciences (2) · Asan Medical Center (1) · Asklepios proresearch (1) · Assistance Publique - Hôpitaux de Paris (1) · Assiut University (1) · Ataturk University (1)
United States (33) · Canada (8) · Germany (7) · United Kingdom (7) · China (6) · Italy (6) · Denmark (5) · France (5) · Sweden (5) · Netherlands (4) · Czechia (3) · Australia (2) · Belgium (2) · Russia (2) · South Korea (2)
Robert Simari, MD (3) · Jonatan Oras, MD, PhD (2) · Roman E Batalov, M.D. (2) · Tariel A Atabekov, Ph.D. (2) · Adil Bashir, PhD (1) · Adrian Covic, Professor (1) · Alan Kadish, MD (1) · Amr A Youssef, MD (1) · Andrea di Lenarda, M.D. (1) · Andrew J. Einstein, MD, PhD (1) · Andrew M South, MD, MS (1) · Cafer Zorkun, MD PhD (1) · Carmelo Carlo-Stella, MD,Prof (1) · Chengxing Shen, Dr. (1) · Christina Eintrei, Professon (1)
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U01HL087318 (3), 2005 (1), K23HL148394 (1), R01HL091069 (1), R01HL165840 (1)