29 terminated. 29 Phase 3, 6 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 29 | Terminated 29 |
| Phase 2 | 6 | Terminated 6 |
Follow Ischemic Stroke: new trials by email Literature Review of Ischemic Stroke trials Research Report on Ischemic Stroke
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Maimonides Minocycline in Stroke Study Minocycline - Stroke, Acute, Ischemic Stroke | Phase 2 / Phase 3 | Terminated | Maimonides Medical Center | 2 | 2023-11-01 | 2025-12-17 |
| Improving Neurological Outcome for Acute Basilar Artery Occlusion With Sufficient Recanalization After Thrombectomy by Intraarterial Tenecteplase (INSIST-IT) Tenecteplase - Stroke, Ischemic | Phase 3 | Terminated | General Hospital of Shenyang Military Region | 145 | 2023-03-21 | 2025-07-02 |
| Comparing Between CO2 and Phenylephrine Treatment in Patients With Progressive Lacunar Infarction (CARBOGEN Study) carbogen, phenylephrine - Acute Ischemic Stroke | Phase 3 | Terminated | Yonsei University | 3 | 2021-04-05 | 2025-01-14 |
| Extending the Time Window for Tenecteplase by Effective Reperfusion in Patients with Large Vessel Occlusion Tenecteplase, Standard Care (which may include intravenous Alteplase) - Ischemic Stroke | Phase 3 | Terminated | University of Melbourne | 242 | 2020-08-01 | 2025-01-15 |
| The Norwegian Tenecteplase Stroke Trial 2 Tenecteplase, Alteplase - Stroke, Acute, Cerebrovascular Disorders | Phase 3 | Terminated | Haukeland University Hospital | 201 | 2019-10-28 | 2025-03-03 |
| MultiStem® Administration for Stroke Treatment and Enhanced Recovery Study MultiStem, Placebo - Ischemic Stroke | Phase 3 | Terminated | Healios K.K. | 206 | 2018-07-28 | 2026-08-11 |
| AtRial Cardiopathy and Antithrombotic Drugs In Prevention After Cryptogenic Stroke Apixaban, Aspirin - Stroke | Phase 3 | Terminated | Columbia University | 1015 | 2018-01-19 | 2025-04-09 |
| Tirofiban for Patients Treated With Alteplase Tirofiban, Alteplase - Ischemic Stroke | Phase 2 / Phase 3 | Terminated | Capital Medical University | 30 | 2017-12-16 | 2020-09-09 |
| Contrast Enhanced Sonothrombolysis and Sonolysis in Stroke - a Swedish Study (CE-5S) SonoVue, Sodium chloride, Transcranial Ultrasound - Ischemic Stroke | Phase 3 | Terminated | Umeå University | 1 | 2017-11-28 | 2018-05-11 |
| Rivaroxaban Versus Aspirin in Secondary Prevention of Stroke and Prevention of Systemic Embolism in Patients With Recent Embolic Stroke of Undetermined Source (ESUS) Rivaroxaban (Xarelto, BAY59-7939), Acetylsalicylic acid (Aspirin, BAY1019036), Rivaroxaban-Placebo - Stroke | Phase 3 | Terminated | Bayer | 7213 | 2014-12-23 | 2019-01-09 |
| DLBS1033 for Acute Ischemic Stroke Patients DLBS1033, Placebo - Acute Ischemic Stroke, Partial Anterior Circulation Infarct | Phase 2 / Phase 3 | Terminated | Dexa Medica Group | 80 | 2014-11-11 | 2023-12-12 |
| DLBS1033 for the Treatment of Acute Ischemic Stroke Placebo, DLBS1033 - Acute Ischemic Stroke | Phase 3 | Terminated | Dexa Medica Group | 9 | 2014-10-01 | 2017-05-04 |
| Cooling Plus Best Medical Treatment Versus Best Medical Treatment Alone for Acute Ischaemic Stroke Hypothermia, Buspirone, Pethidine - Acute Ischemic Stroke | Phase 3 | Terminated | University of Erlangen-Nürnberg Medical School | 98 | 2013-07-01 | 2019-10-02 |
| IMPACT- 24Bt Post Mech. Thrombectomy and/or rtPA TRIAL IMPlant Augmenting Cerebral Blood Flow 24 Hours From Stroke Onset The Ischemic Stroke System, Sham control - Ischemic Stroke | Phase 3 | Terminated | BrainsGate | 27 | 2013-05-01 | 2018-06-26 |
| Phase 3, Randomized, Placebo-Controlled, Double-Blinded Trial of the Combined Lysis of Thrombus With Ultrasound and Systemic Tissue Plasminogen Activator (tPA) for Emergent Revascularization in Acute Ischemic Stroke Transcranial ultrasound as an adjunctive therapy to tPA, Standard of care tPA therapy for acute ischemic stroke - Acute Ischemic Stroke | Phase 3 | Terminated | Cerevast Therapeutics, Inc. | 675 | 2013-05-01 | 2015-04-07 |
| Randomized Controlled Study of the Effectiveness of IV Fluid Infusion in Patients With Acute Ischemic Stroke (IVIS) 0.9% NaCl solution - Ischemic Stroke | Phase 3 | Terminated | Chulalongkorn University | 120 | 2013-05-01 | 2015-08-04 |
| Hypothermia in Acute Stroke With Thrombolysis Imaging Evaluation of Revascularization IV t-PA and normothermia, IV-tPA and hypothermia - Acute Ischemic Stroke | Phase 2 / Phase 3 | Terminated | University of California, Los Angeles | 6 | 2013-02-01 | 2017-04-13 |
| Endovascular Treatment for Small Core and Proximal Occlusion Ischemic Stroke Endovascular thrombectomy/thrombolysis - Ischemic Stroke | Phase 3 | Terminated | University of Calgary | 316 | 2013-01-01 | 2015-03-23 |
| Endovascular Revascularization With Solitaire Device Versus Best Medical Therapy in Anterior Circulation Stroke Within 8 Hours Solitaire FR device, Medical treatment - Acute Stroke | Phase 3 | Terminated | Fundacio Ictus Malaltia Vascular | 206 | 2012-11-01 | 2016-02-03 |
| Efficacy and Safety Study of DP-b99 in Treating Acute Ischemic Stroke DP-b99, Placebo - Acute Ischemic Stroke | Phase 3 | Terminated | D-Pharm Ltd. | 446 | 2009-12-01 | 2012-10-24 |
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Stroke (14) · Cerebrovascular Disorders (2) · Hypothermia (2) · Ischemic Attack, Transient (2) · Acute Disease (1) · Brain Ischemia (1) · Carotid Stenosis (1) · Cerebral Infarction (1) · Constriction, Pathologic (1) · Hemorrhagic Stroke (1) · Intracranial Hemorrhages (1) · Stroke, Lacunar (1) · Thromboembolism (1) · Thrombosis (1)
Brain Diseases (29) · Cardiovascular Diseases (29) · Central Nervous System Diseases (29) · Nervous System Diseases (29) · Vascular Diseases (29) · Cerebrovascular Disorders (27) · Stroke (15) · Pathological Conditions, Signs and Symptoms (6) · Brain Ischemia (3) · Pathologic Processes (3) · Body Temperature Changes (2) · Brain Infarction (2) · Embolism and Thrombosis (2) · Infarction (2) · Ischemia (2)
Abciximab (3) · Aspirin (3) · Tenecteplase (3) · Tissue Plasminogen Activator (3) · DLBS 1033 (2) · Sodium Chloride (2) · Standard of Care (2) · Albumins (1) · Buspirone (1) · Clopidogrel (1) · Cytidine Diphosphate Choline (1) · DP-b99 (1) · Fibrinolytic Agents (1) · Meperidine (1) · Minocycline (1)
Dexa Medica Group (2) · University of Zurich (2) · Bayer (1) · BrainsGate (1) · Capital Medical University (1) · Centocor, Inc. (1) · Cerevast Therapeutics, Inc. (1) · Chulalongkorn University (1) · Codman & Shurtleff (1) · Columbia University (1) · D-Pharm Ltd. (1) · Ferrer Internacional S.A. (1) · Fundacio Ictus Malaltia Vascular (1) · General Hospital of Shenyang Military Region (1) · H. Lundbeck A/S (1)
United States (11) · Canada (8) · Germany (6) · Spain (6) · Switzerland (5) · Australia (3) · Brazil (3) · China (3) · Finland (3) · France (3) · Israel (3) · Italy (3) · Portugal (3) · South Africa (3) · South Korea (3)
Ralf W. Baumgartner, MD (2) · Alex Rovira, MD (1) · Andrew M Demchuk, MD FRCPC (1) · Angel Chamorro, MD (1) · Ashfaq Shuaib, MD (1) · Bryan Due, Ph.D. (1) · Carlos Molina, MD (1) · David S Liebeskind, MD (1) · Diah H Soeryaningtias, Sp.S, MD (1) · Dian Cahyani, Sp.S, MD (1) · Dodik Tugasworo, Sp.S(K), MD (1)
PMID 30045949, PMID 18032739, PMID 21546491, PMID 22691567, PMID 23390923, PMID 24076337, PMID 24335227, PMID 24473178, PMID 24699059, PMID 24815501, PMID 24828363, PMID 24876261, PMID 25342652, PMID 25428822, PMID 25671798, PMID 25791716, PMID 25803346, PMID 25858239, PMID 25882510, PMID 25953374, PMID 25984876, PMID 26120902, PMID 26138125, PMID 26325387, PMID 26486865, PMID 26508752, PMID 26542697, PMID 26892284, PMID 26956258, PMID 27076599, PMID 27462118, PMID 27803391, PMID 27834743, PMID 27924049, PMID 27940648, PMID 28292867, PMID 28318984, PMID 28336740, PMID 28468840, PMID 28483774, PMID 29021311, PMID 29096678, PMID 29170266, PMID 29187242, PMID 29191873, PMID 29203689, PMID 29525076, PMID 29766772, PMID 30878103, PMID 31008276
U01NS054630 (2), 2008 (1), 2018 (1), R01NS077706 (1), U01NS052220 (1), U01NS095869 (1)