108 completed. 108 Phase 1, 53 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 108 | Completed 108 |
| Phase 2 | 53 | Completed 53 |
Follow Ischemia: new trials by email Literature Review of Ischemia trials Research Report on Ischemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Research Study to Evaluate the Safety and Preliminary Efficacy of SGC001 in Patients With Myocardial Infarction SGC001, Placebo - Anterior Myocardial Infarction | Phase 1 | Completed | Beijing Sungen Biomedical Technology Co., Ltd | 38 | 2025-01-20 | 2026-01-12 |
| A Research Study to Evaluate the Safety and Tolerability of SGC001 in Healthy Subjects SGC001, Placebo - Anterior Myocardial Infarction | Phase 1 | Completed | Beijing Sungen Biomedical Technology Co., Ltd | 49 | 2024-08-20 | 2025-11-25 |
| Oral Nicorandil for Prevention of No Reflow Phenomenon in Anterior STEMI Patients Undergoing PPCI Nicorandil 20mg - No Reflow Phenomenon, Anterior STEMI | Phase 1 / Phase 2 | Completed | Ain Shams University | 300 | 2024-03-10 | 2025-08-24 |
| Study to Compare the Pharmacodynamics and Pharmacokinetics of Acetylsalicylic Acid Powder for Oral Inhalation With Non-enteric-coated Chewable Aspirin in Healthy Adults. ASA, non-enteric-coated chewable aspirin - Healthy Volunteers | Phase 1 | Completed | Vectura, Inc. | 86 | 2022-10-14 | 2024-03-22 |
| A Study of NP-011 in Healthy Volunteers NP-011 (Single Ascending Dose Phase), NP-011 (Multiple Ascending Dose Phase), NP-011 (Placebo) - Myocardial Infarction | Phase 1 | Completed | Nexel Co., Ltd. | 64 | 2022-06-10 | 2023-08-03 |
| MiSaver® Stem Cell Treatment for Heart Attack (Acute Myocardial Infarction) MiSaver® - Myocardial Infarction | Phase 1 / Phase 2 | Completed | Honya Medical Inc | 11 | 2021-01-26 | 2024-03-29 |
| Efficacy and Safety of Mesenchymal Stem Cell Clusters in Patients with Critical Limb Ischemia Clusters of adipose-derived mesenchymal stem cells (Dose: 1 x 10^7 cells/1 mL/vial), Clusters of adipose-derived mesenchymal stem cells (Dose: 1 x 10^8 cells/1 mL/vial) - Critical Limb Ischemia | Phase 1 / Phase 2 | Completed | S.Biomedics Co., Ltd. | 20 | 2020-11-04 | 2024-08-30 |
| SP16 Inflammatory Response Inhibition Trial SP16 - Myocardial Infarction, Inflammation | Phase 1 / Phase 2 | Completed | Serpin Pharma, LLC | 10 | 2020-02-24 | 2023-01-30 |
| Epicardial Delivery of XC001 Gene Therapy for Refractory Angina Coronary Treatment (The EXACT Trial) AdVEGFXC1 - Coronary Artery Disease, Ischemia | Phase 1 / Phase 2 | Completed | XyloCor Therapeutics, Inc. | 41 | 2020-01-24 | 2024-01-30 |
| Neuroinflammation After Myocardial Infarction - Imaging Substudy [18F]DPA-714-PET/MRI - Myocardial Infarction | Phase 1 | Completed | University of Alabama at Birmingham | 6 | 2019-10-17 | 2026-08-26 |
| Clopidogrel Aspirin Therapy (CAT) Versus Apixiban Aspirin Therapy (AAT) After Lower Limb Revascularization Combination drug - Ischemia, Anticoagulants | Phase 1 / Phase 2 | Completed | Mansoura University | 1536 | 2019-07-03 | 2022-07-19 |
| The MOCA I Study - Microvascular Obstruction with CoFI™ System Assessment CorFlow Controlled Flow Infusion System - CoFI™ - STEMI - ST Elevation Myocardial Infarction, Microvascular Obstruction | Phase 1 | Completed | CorFlow Therapeutics AG | 73 | 2019-06-04 | 2025-03-19 |
| Pericardial Matrix With Mesenchymal Stem Cells for the Treatment of Patients With Infarcted Myocardial Tissue PeriCord: Expanded and cryopreserved allogeneic umbilical cord Wharton´s jelly-derived adult mesenchymal stem cells colonized on human pericardial matrix., Surgery by sternotomy - Myocardial Infarction | Phase 1 | Completed | Fundació Institut Germans Trias i Pujol | 12 | 2019-05-13 | 2022-12-02 |
| Bone Marrow Mononuclear Cells vs Mesenchymal Stem Cells in Diabetic Patients With Chronic Limb Ischemia Cell-based therapy - Chronic Limb-threatening Ischemia, Diabetes Mellitus | Phase 1 / Phase 2 | Completed | Fundación Oftalmológica de Santander Clínica Carlos Ardila Lulle | 24 | 2019-01-01 | 2022-11-30 |
| A Safety and Tolerability Study of RJX Drug Product in Healthy Participants RJX, Placebo - Critical Limb Ischemia | Phase 1 | Completed | Reven Pharmaceuticals, Inc. | 76 | 2018-08-24 | 2020-04-27 |
| Rituximab in Patients With Acute ST-elevation Myocardial Infarction Study RiTUXimab Injection - Ischemic Heart Disease, Myocardial Infarction | Phase 1 / Phase 2 | Completed | Papworth Hospital NHS Foundation Trust | 24 | 2017-06-01 | 2021-09-14 |
| A Clinical and Histological Analysis of Mesenchymal Stem Cells in Amputation Allogeneic bone marrow derived mesenchymal stem cells - Ischemia, Peripheral Arterial Disease | Phase 1 | Completed | Indiana University | 81 | 2017-01-23 | 2025-09-23 |
| Use of Autologous Concentrated Bone Marrow Aspirate in Preventing Wound Complications in Below Knee Amputation (BKA) Injection of cBMA aspirate into the index leg - Peripheral Artery Disease, Vascular Disease | Phase 1 | Completed | Michael Murphy | 6 | 2017-01-06 | 2024-12-12 |
| Safety/Feasibility of Vonapanitase Following Angioplasty for Patients With Peripheral Artery Disease (PAD) Below the Knee (BTK) vonapanitase, Placebo - Peripheral Artery Disease | Phase 1 | Completed | Proteon Therapeutics | 29 | 2016-11-01 | 2019-05-02 |
| Safety and Feasibility of Intracoronary Hypothermia in Acute Myocardial Infarction intracoronary infusion with saline on 22 and 4°C - Myocardial Infarction | Phase 1 / Phase 2 | Completed | Catharina Ziekenhuis Eindhoven | 10 | 2016-06-01 | 2016-11-22 |
Showing 20 of 108. Sign in to see all of them.
Myocardial Infarction (42) · Chronic Limb-Threatening Ischemia (27) · Stroke (18) · Peripheral Arterial Disease (14) · Peripheral Vascular Diseases (12) · Coronary Artery Disease (11) · Heart Failure (7) · ST Elevation Myocardial Infarction (7) · Cardiovascular Diseases (6) · Inflammation (6) · Infarction, Middle Cerebral Artery (5) · Ischemic Stroke (5) · Acute Coronary Syndrome (4) · Arterial Occlusive Diseases (3)
Pathological Conditions, Signs and Symptoms (108) · Pathologic Processes (107) · Vascular Diseases (98) · Cardiovascular Diseases (97) · Necrosis (60) · Infarction (55) · Heart Diseases (51) · Myocardial Ischemia (49) · Arteriosclerosis (40) · Arterial Occlusive Diseases (38) · Atherosclerosis (29) · Chronic Disease (27) · Disease Attributes (27) · Nervous System Diseases (21)
Aspirin (2) · Cell- and Tissue-Based Therapy (2) · Plasmalyte A (2) · Saline Solution (2) · Sodium Chloride (2) · 3-(2,4-diamino-6-(3-hydroxyphenyl)pteridin-7-yl)phenol (1) · Atorvastatin (1) · Capsules (1) · Celecoxib (1) · Constraint Induced Movement Therapy (1) · Continuous Positive Airway Pressure (1) · Control Groups (1) · Docosahexaenoic Acids (1) · Drug Combinations (1) · EVP 1001-1 (1)
Andalusian Initiative for Advanced Therapies - Fundación Pública Andaluza Progreso y Salud (2) · Beijing Sungen Biomedical Technology Co., Ltd (2) · Cedars-Sinai Medical Center (2) · Emory University (2) · Losordo, Douglas, M.D. (2) · Pluristem Ltd. (2) · Stanford University (2) · Stempeutics Research Pvt Ltd (2) · TCA Cellular Therapy (2) · University of Southern California (2) · Xijing Hospital (2) · Abbott Medical Devices (1) · AdvanceCor GmbH (1) · Ain Shams University (1) · Aldagen (1)
United States (50) · Germany (8) · Spain (7) · Netherlands (6) · China (5) · India (4) · Switzerland (4) · Brazil (3) · Canada (3) · Denmark (3) · United Kingdom (3) · Australia (2) · Egypt (2) · France (2) · Ireland (2)
Michael P Murphy, MD (2) · Adelino Leite-Moreira, PhD (1) · Ana Paula CP Carlotti, 1 (1) · Andreas Wielgosz, MD, FRCP(C) (1) · Andrew Pipe, MD (1) · Antonio Abbate, MD, PhD (1) · Antonio Chacon, MD, PhD (1) · Antonio De la Cuesta, MD (1) · Attilio Odero, Professor (1) · Cameron R. Smith, M.D., Ph.D. (1) · Carolee Winstein, PhD, PT, FAPTA (1) · Chris Blanchard, PhD (1)
PMID 22163120, PMID 35802393, PMID 15246726, PMID 19301723, PMID 19679246, PMID 19711453, PMID 19958962, PMID 19996767, PMID 20078390, PMID 20705929, PMID 21330601, PMID 21422390, PMID 21454794, PMID 21492763, PMID 21502572, PMID 21594960, PMID 21717276, PMID 22052917, PMID 22088800, PMID 22198979, PMID 22264202, PMID 22336189, PMID 22764211, PMID 22877866, PMID 22951358, PMID 22965994, PMID 22971949, PMID 23192920, PMID 23633132, PMID 23758736, PMID 23778184, PMID 23979567, PMID 24001533, PMID 24036024, PMID 24218170, PMID 24815497, PMID 25102193, PMID 25107583, PMID 25484310, PMID 25567765, PMID 25872588, PMID 26148006, PMID 26428987, PMID 26526721, PMID 27322478, PMID 28566292, PMID 29395424, PMID 30156755, PMID 30602360, PMID 31164067
2008 (1), 2014 (1), 2018 (1), R01HD065438 (1), R01HL103927 (1), U54HL081028 (1)