10 completed, 7 unknown, 4 recruiting, 1 terminated. 9 Phase 2, 9 Phase 3, 4 Phase 1, 3 Phase 4, 1 Not applicable.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A First-in-Human Trial of DS3790a in Participants With Hematological Malignancies DS3790a, Combination drug - Hematological Malignancies, B-cell Non-Hodgkin Lymphoma | Phase 1 / Phase 2 | Recruiting | Daiichi Sankyo | 420 | 2026-01-16 | 2026-08-24 |
| Anesthesia Techniques, Neuroprotection and Surgical Field in FESS Under Controlled Hypotension Propofol / Remifentanil, Ketamine + Magnesium sulfate (drug combination), Sevoflurane and Remifentanil - Magnesium Sulfate, Remifentanil | Not applicable | Recruiting | University General Hospital of Patras | 150 | 2025-09-11 | 2025-09-18 |
| A Exploratory Study of Vγ2Vδ2 T Lymphocyte-based Immunotherapy for MDR-TB Vγ2Vδ2 T lymphocyte-based immunotherapy, Treatment regimens for MDR-TB - MDR-TB, Immunotherapy | Phase 4 | Recruiting | Shanghai Pulmonary Hospital, Shanghai, China | 30 | 2022-08-03 | 2022-08-10 |
| A Phase II Randomized Therapeutic Optimization Trial for Subjects With Refractory Metastatic Colorectal Cancer Using ctDNA: Rapid 1 Trial Signatera ctDNA assay, pre-specified sequence of FDA-approved drugs and drug combinations - Metastatic Colorectal Cancer | Phase 2 | Terminated | University of Florida | 6 | 2022-03-14 | 2025-07-01 |
| Niraparib and Dostarlimab in HRD Solid Tumors Combination drug - Homologous Recombination Deficient Solid Tumors | Phase 2 | Unknown | West Cancer Center | 30 | 2021-11-29 | 2023-12-21 |
| Ketamine + Magnesium for Chronic Cluster Headache (KETALGIA) Ketamine + Magnesium sulfate (drug combination) - Refractory Chronic Cluster Headache | Phase 4 | Completed | University Hospital, Clermont-Ferrand | 93 | 2021-09-15 | 2026-05-08 |
| An Investigator Initiated Prospective, Four Arms Randomized Comparative Study of Efficacy and Safety of Saroglitazar, Vitamin E and Life Style Modification in Patients With Nonalcoholic Fatty Liver Disease (NAFLD)/ Non-alcoholic Steatohepatitis (NASH) Saroglitazar, Vitamin E, Combination drug - NAFLD | Phase 3 | Unknown | Asian Institute of Gastroenterology, India | 250 | 2021-01-31 | 2021-01-26 |
| Induction Chemotherapy for Locally Recurrent Rectal Cancer Combination drug, Chemoradiotherapy, Surgery locally recurrent rectal cancer - Recurrent Rectal Cancer | Phase 3 | Recruiting | Catharina Ziekenhuis Eindhoven | 364 | 2020-11-13 | 2022-09-06 |
| A Phase 3 Randomized Double Blind Efficacy and Safety Study of Oral Polio Vaccine and NA-831 for Covid-19 Biological: oral polio vaccine, Comparable Placebo, NA-831 - Covid19, SARS (Severe Acute Respiratory Syndrome) | Phase 3 | Unknown | Biomed Industries, Inc. | 3600 | 2020-11-01 | 2020-09-09 |
| Clinical Trail to Evaluate the Efficacy and Safety of DWJ1451 Amlodipine/Olmesartan 10/40mg (Combination drug), Ezetimibe/Rosuvastatin 10/20mg(Combination drug), Olmesartan 40mg, Ezetimibe/Rosuvastatin 10/20mg(Combination drug), Amlodipine/Olmesartan 10/40mg (Combination drug) - Hypertension, Dyslipidemia | Phase 3 | Unknown | Daewoong Pharmaceutical Co. LTD. | 237 | 2019-11-20 | 2019-11-13 |
| Roll-over Study to Continue Treatment With the Investigational Drug Rogaratinib and to Further Test Its Safety Rogaratinib (BAY1163877), Combination drug - Cancer | Phase 2 | Completed | Bayer | 1 | 2019-10-30 | 2022-04-01 |
| Selinexor as Single Agent and With Imatinib in Metastatic and/or Unresectable Gastrointestinal Stromal Tumors (SeliGIST) Selinexor, Imatinib - Maximum Tolerated Dose, GIST | Phase 1 / Phase 2 | Unknown | Grupo Espanol de Investigacion en Sarcomas | 30 | 2019-08-16 | 2023-03-27 |
| Clopidogrel Aspirin Therapy (CAT) Versus Apixiban Aspirin Therapy (AAT) After Lower Limb Revascularization Combination drug - Ischemia, Anticoagulants | Phase 1 / Phase 2 | Completed | Mansoura University | 1536 | 2019-07-03 | 2022-07-19 |
| Combination of Anti-PD-1 Antibody and Chemotherapy in Metastatic Pancreatic Cancer Combination drug, Chemotherapy - Pancreatic Cancer | Phase 2 | Completed | Zhejiang University | 110 | 2019-03-27 | 2023-01-27 |
| Daratumumab With DCEP for Multiple Myeloma With Plasmacytoma Drug Combinations - Multiple Myeloma in Relapse, Plasmacytoma | Phase 2 | Unknown | Seoul National University Hospital | 33 | 2019-01-14 | 2019-08-22 |
| Clinical Trial of Temisartan/Amlodipine & Rosuvastatin in Subjects With Hypertension and Hyperlipidemia Temisartan+Amlodipine+Rosuvastatin (Combination drug), Temisartan+Amlodipine, Temisartan+Rosuvastatin - Hypertension, Hyperlipidemia | Phase 3 | Completed | Yuhan Corporation | 202 | 2017-04-11 | 2019-01-16 |
| A Clinical Trial to Evaluate the Efficacy and Safety of Olmesartan/Amlodipine/Rosuvastatin Combination Treatment in Patients With Concomitant Hypertension and Hyperlipidemia Amlodipine/Olmesartan 10/40mg (Combination drug), Rosuvastatin 20mg, Olmesartan 40 mg, Rosuvastatin 20mg, Amlodipine/Olmesartan 10/40mg (Combination drug) - Hypertension, Hyperlipidemias | Phase 3 | Completed | Daewoong Pharmaceutical Co. LTD. | 265 | 2017-01-01 | 2022-01-11 |
| Neoadjuvant Chemotherapy for the Treatment of Resectable Locally Advanced Colon Cancer Postoperative chemotherapy, Neoadjuvant chemotherapy - Colon Cancer | Phase 2 / Phase 3 | Unknown | The First Affiliated Hospital with Nanjing Medical University | 400 | 2016-12-01 | 2016-08-30 |
| The Effect of Subsartorial Saphenous Block on Postoperative Pain Following Major Ankle and Hind Foot Surgery Bupivacaine-epinephrine, Placebo - Arthrosis, Arthritis | Phase 4 | Completed | University of Aarhus | 18 | 2016-06-21 | 2017-03-27 |
| Combined Medication for Improved Analgesia in Superficial Pain Diclofenac and Atropine combination drug, Placebo - Pain | Phase 3 | Completed | Brigham and Women's Hospital | 100 | 2014-04-01 | 2018-07-03 |
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Hypertension (3) · Hyperlipidemias (2) · Acrocephalosyndactylia (1) · Arthritis (1) · Brain Ischemia (1) · Breast Neoplasms (1) · COVID-19 (1) · Carcinoma, Non-Small-Cell Lung (1) · Carcinoma, Transitional Cell (1) · Cluster Headache (1) · Colonic Neoplasms (1) · Colorectal Neoplasms (1) · Drug-Related Side Effects and Adverse Reactions (1) · Dyslipidemias (1) · Head and Neck Neoplasms (1)
Daewoong Pharmaceutical Co. LTD. (2) · Asian Institute of Gastroenterology, India (1) · Bayer (1) · Biomed Industries, Inc. (1) · Brigham and Women's Hospital (1) · Catharina Ziekenhuis Eindhoven (1) · Daiichi Sankyo (1) · Grupo Espanol de Investigacion en Sarcomas (1) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (1) · Labopharm Inc. (1) · Mansoura University (1) · Seoul National University Hospital (1) · Shanghai Pulmonary Hospital, Shanghai, China (1) · The First Affiliated Hospital with Nanjing Medical University (1) · University General Hospital of Patras (1)
United States (6) · South Korea (4) · Belgium (2) · China (2) · France (2) · Canada (1) · Denmark (1) · Egypt (1) · Greece (1) · India (1) · Italy (1) · Japan (1) · Netherlands (1) · New Zealand (1) · Norway (1)
Cesar Serrano, MD (1) · Fumin Zhang, Professor (1) · Gregory Vidal, MD (1) · Hyunhee Na, MD (1) · Lloyd Tran, PhD (1) · Nshaat A Elsaadany, MSc (1) · Pim Burger, MD (1) · Robert R Edwards, PHD (1) · Sherise Rogers, MD (1) · Thomas Fichtner Bendtsen, MD, phD (1)
PMID 22458917, PMID 28178072, PMID 29667940, PMID 32937023, PMID 36877132, PMID 37052821
2017 (1), 2019 (1), 2025 (1)