4 completed, 1 terminated, 1 unknown, 1 withdrawn. 4 Phase 1, 3 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 3, Withdrawn 1 |
| Phase 2 | 3 | Completed 2, Unknown 1 |
| Phase 3 | 1 | Terminated 1 |
Follow Aldagen: new trials by email
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Patients With Intermittent Claudication Injected With ALDH Bright Cells ALD-301, Placebo (vehicle) - Peripheral Artery Disease, Intermittent Claudication | Phase 2 | Completed | The University of Texas Health Science Center, Houston | 82 | 2013-06-01 | 2017-04-21 |
| Study of ALD-401 Via Intracarotid Infusion in Ischemic Stroke Subjects ALD-401, Sham Procedure - Stroke, Ischemic Stroke | Phase 2 | Unknown | Aldagen | 100 | 2011-03-01 | 2014-01-16 |
| Fetal Umbilical Cord Blood (UCB) Transplant for Lysosomal Storage Diseases ALD-601 - Lysosomal Storage Diseases, Inborn Errors of Metabolism | Phase 1 | Withdrawn | Joanne Kurtzberg, MD | 2009-10-01 | 2017-06-29 | |
| ALD-101 Adjuvant Therapy of Unrelated Umbilical Cord Blood Transfusion (UCBT) in Patients With Inherited Metabolic Diseases ALD-101 - Inherited Metabolic Diseases, Lysosomal Storage Disorders | Phase 3 | Terminated | Aldagen | 40 | 2008-03-01 | 2014-07-08 |
| ALD-301 for Critical Limb Ischemia, Randomized Trial ALDH-br bone marrow cells vs. mononuclear bone marrow cells - Critical Limb Ischemia, Peripheral Arterial Disease | Phase 1 / Phase 2 | Completed | Aldagen | 20 | 2006-10-01 | 2009-05-14 |
| Intramyocardial Injection of Autologous Aldehyde Dehydrogenase-Bright Stem Cells for Therapeutic Angiogenesis (FOCUS Br) Stem Cell Therapy, Control (plasma) - Coronary Artery Disease | Phase 1 | Completed | Texas Heart Institute | 21 | 2006-04-01 | 2024-04-23 |
| Unrelated Umbilical Cord Blood Transplantation Augmented With ALDHbr Umbilical Cord Blood Cells ALDHbr Umbilical Cord Blood Cells - MDS, Anemia, Aplastic | Phase 1 | Completed | Joanne Kurtzberg, MD | 37 | 2005-10-01 | 2017-06-29 |
Metabolism, Inborn Errors (3) · Ischemia (2) · Lysosomal Storage Diseases (2) · Mucopolysaccharidosis I (2) · Mucopolysaccharidosis II (2) · Peripheral Arterial Disease (2) · Adrenoleukodystrophy (1) · Anemia, Aplastic (1) · Canavan Disease (1) · Chronic Limb-Threatening Ischemia (1) · Coronary Artery Disease (1) · Fucosidosis (1) · Gangliosidoses, GM2 (1) · Gangliosidosis, GM1 (1) · Hematologic Neoplasms (1)
United States (7)
Joanne Kurtzberg, MD (3) · Emerson C Perin, M.D., Ph.D. (1) · Emerson Perin, MD, PhD (1) · Farrell Mendelsohn, MD (1) · James Hinson, MD (1) · James M Hinson, MD (1) · Michael Murphy, MD (1) · Nicolas Chronos, MD (1) · Robert Mitchell, MD (1) · Robert Simari, MD (1)
PMID 21594960, PMID 28209728, PMID 30586746
UM1HL087318-06 (1)