22 completed, 7 unknown, 6 not yet recruiting, 4 recruiting. 19 Not applicable, 3 Phase 4, 1 Phase 1, 1 Phase 2, 1 Phase 3.
Follow Intracranial Pressure: new trials by email Literature Review of Intracranial Pressure trials Research Report on Intracranial Pressure
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Optimal Cerebral Perfusion Pressure Guided Therapy: Assessment of Target Effectiveness - II Optimal cerebral perfusion pressure - Traumatic Brain Injury, Severe Traumatic Brain Injury | Not applicable | Not yet recruiting | Maastricht University Medical Center | 62 | 2027-01-01 | 2026-09-28 |
| JUgular Gating for Upright Level Adjustment and Targeted Enhancement of Cerebral Perfusion Ultrasound assessment - Intracranial Pressure, Critical Care | Not yet recruiting | University Hospital, Bordeaux | 30 | 2026-09-01 | 2026-06-24 | |
| Remifentanil vs Esmolol During Intubation for Cerebral Aneurysm Coil Embolization Remifentanil, Esmolol - Cerebral Aneurysm Unruptured, Intracranial Pressure | Not applicable | Not yet recruiting | Fatih Sultan Mehmet Training and Research Hospital | 84 | 2026-06-22 | 2026-06-22 |
| Effect of Internal Jugular Vein Catheterization on Intracranial Pressure and Intracranial Blood Flow Internal Jugular Vein Catheterization - Intracranial Pressure, Ultrasonography | Not yet recruiting | Kanuni Sultan Suleyman Training and Research Hospital | 61 | 2026-04-15 | 2026-04-20 | |
| Comparison of the Effects of Sevoflurane and Desflurane on Optic Nerve Sheath Diameter During Laparoscopic Surgery Sevoflurane, Desflurane - Intracranial Pressure, Laparoscopic Surgery | Not applicable | Completed | Medipol University | 63 | 2026-04-15 | 2026-08-04 |
| Non-Invasive ICP Monitoring Study Brain4Care - Intracranial Pressure | Recruiting | University of Texas Southwestern Medical Center | 30 | 2026-04-10 | 2026-04-22 | |
| Age Related Thresholds for Management of Severe Head Injury in Paediatrics: An Extension of STARSHIP Traumatic Brain Injury, Pediatric | Enrolling by invitation | Cambridge University Hospitals NHS Foundation Trust | 450 | 2026-03-01 | 2026-09-24 | |
| Intracranial Pressure and a Potential Vicious Circle of Atrial Fibrillation in HFpEF Echocardiography - Heart Failure With Preserved Ejection Fraction (HFpEF), Atrial Fibrillation | Completed | Ankara Ataturk Sanatorium Training and Research Hospital | 309 | 2025-10-14 | 2026-04-09 | |
| Non-invasive Intracranial Pressure Estimation by Measurement of the Occlusion Pressure of the Isolated Periorbital Vein CPMX3 - Intracranial Pressure, Intracranial Pressure Changes | Not applicable | Recruiting | Compremium AG | 15 | 2025-09-30 | 2025-10-30 |
| Role of Non-Selective Beta-Adrenergic Blocker in Severe TBI propranolol, normal saline IV - Traumatic Brain Injury (TBI) Patients, Intracranial Pressure | Phase 3 | Not yet recruiting | Tanta University | 60 | 2025-09-20 | 2025-03-11 |
| AI-Based Ultrasound Prediction Model for Intracranial Pressure and Prognosis in Lung Cancer Patients With Leptomeningeal Metastasis: A Dual-Center Study Lung Cancer (NSCLC), Leptomeningeal Metastasis | Not yet recruiting | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 142 | 2025-07-01 | 2025-06-05 | |
| Evaluation of Optic Nerve Sheath Diameter Changes During Cardiopulmonary Bypass in Open Heart Surgery Ultrasonography of the Optic Nerve Sheath - Open Heart Surgery, Cardiopulmonary Bypass | Completed | Medipol University | 40 | 2025-06-10 | 2025-11-28 | |
| Validation of Non-Invasive Intracranial Pressure Estimation Using CPMX3 in the Periorbital Vein: A Feasibility Study in Pediatric Patients CPMX3 measurement - Intracranial Pressure | Not applicable | Withdrawn | Compremium AG | 2025-04-22 | 2026-04-24 | |
| Sevoflurane With or Without Intravenous Lidocaine Infusion Versus Propofol Anesthesia on Intracranial Pressure and Cerebral Oxygenation During Laparoscopic Hysterectomy Propofol, Sevoflurane plus lidocaine infusion, Sevoflurane - Sevoflurane, Lidocaine | Not applicable | Recruiting | Tanta University | 90 | 2025-02-01 | 2025-07-14 |
| The Effect of Arterial Carbon Dioxide Levels on Cerebral Blood Flow and Cerebral Autoregulation in the Steep Trendelenburg Position During Robot-assisted Prostatectomy, and Its Effect on Postoperative Cognition Ventilation strategy - Intracranial Pressure, Circulation System | Not applicable | Completed | University Hospital, Akershus | 46 | 2025-01-24 | 2026-06-02 |
| CoMind Early Feasibility Study Intracranial Pressure, Intracranial Pressure Changes | Recruiting | CoMind Technologies Limited | 581 | 2024-11-27 | 2026-09-29 | |
| Evaluation of Postoperative Intracranial Pressure in Patients Undergoing Intracranial Tumor Surgery USG, BCT - INTRACRANIAL TUMOR, INTRACRANIAL PRESSURE | Not applicable | Unknown | Sezen Kumaş Solak | 50 | 2024-09-15 | 2024-08-19 |
| The Effects of Positive End-expiratory Pressure (PEEP) on Optic Nerve Sheath Diameter in Laparoscopic Cholecystectomy Positive End-Expiratory Pressure (PEEP) - Positive End-expiratory Pressure (PEEP), Intracranial Pressure | Not applicable | Completed | Nigde Omer Halisdemir University | 34 | 2024-05-23 | 2026-06-02 |
| Effects of Different Anesthesia Machine Modalities on Bariatric Surgery Patients: a Prospective Randomized Controlled Study PC Ventilation mode, VC Ventilation mode, PRVC Ventilation mode - Ventilation, Bariatric Surgery | Not applicable | Unknown | Yu-Long Jia | 90 | 2024-03-01 | 2025-03-05 |
| Correlation Patterns of Brain Temperature-Pressure in Acute Brain Injury Brain temperature-pressure monitoring - Intracranial Pressure, Brain Injuries, Traumatic | Completed | Beijing Tiantan Hospital | 208 | 2024-02-15 | 2026-02-09 |
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Brain Injuries, Traumatic (6) · Brain Injuries (3) · Cerebral Hemorrhage (3) · Hydrocephalus (3) · Brain Neoplasms (2) · Pneumoperitoneum (2) · Stroke (2) · Atrial Fibrillation (1) · Brain Diseases (1) · Carcinoma, Non-Small-Cell Lung (1) · Critical Illness (1) · Dementia (1) · Depression (1) · Encephalitis (1) · Hydrocephalus, Normal Pressure (1)
Nervous System Diseases (16) · Central Nervous System Diseases (15) · Brain Diseases (14) · Pathological Conditions, Signs and Symptoms (9) · Craniocerebral Trauma (8) · Trauma, Nervous System (8) · Wounds and Injuries (8) · Pathologic Processes (7) · Brain Injuries (5) · Cardiovascular Diseases (5) · Vascular Diseases (5) · Central Nervous System Neoplasms (4) · Cerebrovascular Disorders (4) · Hemorrhage (4) · Neoplasms (4)
Positive-Pressure Respiration (2) · Propofol (2) · Sevoflurane (2) · Chest Wall Oscillation (1) · Control Groups (1) · Desflurane (1) · Dexmedetomidine (1) · Echocardiography (1) · Mannitol (1) · Propranolol (1) · Remifentanil (1) · Saline Solution, Hypertonic (1) · Spinal Puncture (1) · Ultrasonography (1) · esmolol (1)
Compremium AG (2) · Marmara University (2) · Medipol University (2) · Tanta University (2) · Yonsei University (2) · Abant Izzet Baysal University (1) · Ain Shams University (1) · Ankara Ataturk Sanatorium Training and Research Hospital (1) · Ankara City Hospital Bilkent (1) · Beijing Tiantan Hospital (1) · Beth Israel Deaconess Medical Center (1) · Cambridge University Hospitals NHS Foundation Trust (1) · Carmelo Graffagnino (1) · Centre Hospitalier Universitaire Dijon (1) · Centre Hospitalier Universitaire, Amiens (1)
United States (9) · Turkey (Türkiye) (8) · China (4) · France (4) · Denmark (3) · Egypt (3) · Canada (2) · Netherlands (2) · South Korea (2) · United Kingdom (2) · Brazil (1) · Czechia (1) · Norway (1) · Portugal (1)
Ruslan Abdullayev (2) · Azam Ahmed, MD (1) · Carmelo Graffagnino, MD (1) · DaiWai M Olson, PhD RN (1) · DaiWai M Olson, PhD RN CCRN (1) · Guoyi Gao, MD (1) · Huda Elkallaf, Resident (1) · Marianne Marianne, D.M.Sc. (1) · Ramani Balu, MD, PhD (1) · Rigmor H Jensen, Professor (1)
PMID 10969042, PMID 27012512, PMID 28219399, PMID 30215286, PMID 31978945, PMID 32015507, PMID 32150360, PMID 32230900, PMID 32283294, PMID 32314810, PMID 32747697, PMID 38773608, PMID 42000868, PMID 42256563, PMID 42447921