56 completed, 8 not yet recruiting, 7 recruiting, 7 unknown. 69 Not applicable, 6 Phase 3, 5 Phase 2, 2 Phase 1, 1 Phase 4.
Follow Positive-Pressure Respiration: new trials by email Literature Review of Positive-Pressure Respiration trials Research Report on Positive-Pressure Respiration
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| One-Hour Positive Pressure Ventilation After a Pressure Support Spontaneous Breathing Trial One-hour positive pressure ventilation, Immediate extubation - Airway Extubation, Weaning Mechanical Ventilation | Not applicable | Not yet recruiting | Hospital do Coracao | 4000 | 2027-01-01 | 2026-09-22 |
| One-Hour Positive Pressure Ventilation After a T-Piece Spontaneous Breathing Trial One-hour positive pressure ventilation, Immediate extubation - Airway Extubation, Extubation Failure | Not applicable | Not yet recruiting | Hospital do Coracao | 4000 | 2027-01-01 | 2026-09-22 |
| Mechanical Ventilator Adjustments and Patient Dyspnea Change to VC/AC, Change in Tidal Volume, Change in inspiratory flow - Respiratory Failure, Dyspnea During Mechanical Ventilation | Not applicable | Not yet recruiting | Beth Israel Deaconess Medical Center | 20 | 2026-09-01 | 2026-07-14 |
| Two Modalities of Ventilation on the Occurrence of Respiratory Complications During Inhalational Anaesthetic Induction in Children Induction with PEEP (5 cmH2O) and PSV (2-12 cmH2O), Induction in spontaneous breathing - Anaesthetic Induction, Respiratory Complications of Care | Not applicable | Not yet recruiting | Hospices Civils de Lyon | 2032 | 2026-09-01 | 2026-08-17 |
| Comparison of 5 vs 8 cmH₂O PEEP on Respiratory Mechanics in Prone Lumbar Surgery Mechanical Ventilation (PEEP) - Lumbar Disc Herniation, Spinal Surgery | Not applicable | Not yet recruiting | Harran University | 60 | 2026-08-15 | 2026-08-11 |
| Optimal PEEP for Postoperative Oxygenation and Lung Aeration (ULTRASVENT-2) Intraoperative Positive End-Expiratory Pressure (PEEP) Regulation - Postoperative Complications, Respiratory Insufficiency | Not applicable | Not yet recruiting | Moscow Multidisciplinary Clinical Center "Kommunarka" | 360 | 2026-07-01 | 2026-05-29 |
| Influence of Lung Recruitment Potential on Positive End-Expiratory Pressure (PEEP) Titration Strategies in Acute Respiratory Distress Syndrome (ARDS) Patients. Positive End-Expiratory Pressure (PEEP) Titration guided by Static Compliance, Positive End-Expiratory Pressure (PEEP) Titration guided by Transpulmonary Pressure - ARDS (Acute Respiratory Distress Syndrome) | Not applicable | Recruiting | Hospital Dr. Franco Ravera Zunino | 52 | 2026-06-01 | 2026-07-10 |
| HemodynamIc eFfects of Lung Collapse and overdIstension During ARDS Change in PEEP - ARDS, AHRF | Not applicable | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 20 | 2026-02-28 | 2026-02-20 |
| Contribution of Transthoracic and Transcranial Ultrasonography to the Titration of PEEP in Patients With ARDS and ABI Stepwise Positive End-Expiratory Pressure (PEEP) Increase Protocol - Acute Respiratory Distress Syndrome (ARDS), Acute Brain Injury | Not applicable | Recruiting | Theodoros Schizodimos | 30 | 2025-12-01 | 2025-12-31 |
| Effects of Negative Pressure Ventilation Onto Hemodynamics and Right Ventricular Funktion in Patients After Implantation of a Left Ventricular Assist Device. Negative pressure ventilation, positive pressure ventilation - Critical Illness, Heart Failure | Not applicable | Recruiting | Karlsburg Hospital | 30 | 2025-10-01 | 2026-02-18 |
| Effects of Positive End-Expiratory Pressure Levels on Lung Recruitment Duration and Hemodynamics After Alveolar Recruitment Maneuver: A Randomized Clinical Trial lung recruitment maneuvre; PEEP - Dynamic Lung Compliance, Alveolar Recruitment Maneuver | Not applicable | Completed | Northern Jiangsu People's Hospital | 101 | 2025-08-30 | 2026-03-24 |
| Effects of Manual Positive End Expiratory Pressure and Non-invasive Continuous Positive Air Pressure in COPD Patients Manual Positive End Expiratory Pressure (PEEP) Therapy, Non-Invasive CPAP Therapy - COPD | Not applicable | Not yet recruiting | Riphah International University | 42 | 2025-07-28 | 2025-07-23 |
| Effect of Positive End-expiratory Pressure on the Gastric Volume Positive end expiratory pressure - Gastric Volume, Breast Cancer Female | Not applicable | Unknown | Seoul National University Bundang Hospital | 128 | 2025-03-15 | 2025-03-06 |
| Noninvasive Ventilation Facemasks Favoring Carbon Dioxide Washout Noninvasive ventilation - Respiratory Insufficiency | Not applicable | Recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 20 | 2024-11-15 | 2025-09-30 |
| The Effects of Positive End-expiratory Pressure (PEEP) on Optic Nerve Sheath Diameter in Laparoscopic Cholecystectomy Positive End-Expiratory Pressure (PEEP) - Positive End-expiratory Pressure (PEEP), Intracranial Pressure | Not applicable | Completed | Nigde Omer Halisdemir University | 34 | 2024-05-23 | 2026-06-02 |
| Pre- and Postoperative Chest Therapy With Positive Expiratory Pressure (PEP) to Prevent Hospital-acquired Pneumonia positive expiratory pressure - Hip Fractures (ICD-10 72.01-72.2) | Not applicable | Recruiting | University Hospital Bispebjerg and Frederiksberg | 566 | 2024-02-19 | 2025-09-23 |
| Lung Recruitment in Laparoscpic Surgery Positive end expiratory pressure - Atelectasis, Postoperative | Not applicable | Completed | Menoufia University | 93 | 2024-02-01 | 2024-10-16 |
| Individualized Selection of PEEP in Patients Affected by Expiratory Flow Limitation Mechanical ventilation setting (Positive end-expiratory pressure) according to Expiratory Flow Limitation, Mechanical ventilation setting (Positive end-expiratory pressure) not according to Expiratory Flow Limitation - Postoperative Complications, Mechanical Ventilation Complication | Not applicable | Unknown | Università degli Studi di Ferrara | 1536 | 2024-02-01 | 2024-01-22 |
| Effect of PEEP on Gastric Insufflation During Face Mask Induction of General Anesthesia in Children Positive End Expiratory Pressure PEEP - Anesthesia, Child | Not applicable | Completed | Kasr El Aini Hospital | 72 | 2023-10-10 | 2025-08-03 |
| Respiratory and Hemodynamic Targets During General Anesthesia Blood pressure, Positive end expiratory pressure, Tidal volume - Patients Undergoing General Anesthesia | Not applicable | Completed | Lars Wiuff Andersen | 485 | 2023-10-09 | 2025-08-05 |
Showing 20 of 87. Sign in to see all of them.
Respiratory Distress Syndrome (12) · Pulmonary Atelectasis (7) · Obesity (5) · Respiratory Aspiration (5) · Sleep Apnea, Obstructive (5) · Acute Lung Injury (4) · Respiratory Insufficiency (4) · Hypoxia (3) · Lung Diseases (3) · Pneumonia (3) · Postoperative Complications (3) · Ventilator-Induced Lung Injury (3) · Asthma (2) · Brain Injuries (2) · Bronchopulmonary Dysplasia (2)
Seoul National University Hospital (6) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (3) · Capital Medical University (2) · Cliniques universitaires Saint-Luc- Université Catholique de Louvain (2) · Columbia University (2) · Hospices Civils de Lyon (2) · Hospital do Coracao (2) · Region Västmanland (2) · Riphah International University (2) · Umeå University (2) · University of Crete (2) · Balikesir University (1) · Beth Israel Deaconess Medical Center (1) · Brigham and Women's Hospital (1) · Brugmann University Hospital (1)
United States (14) · South Korea (8) · France (7) · Italy (7) · Canada (5) · Sweden (5) · Egypt (4) · Germany (4) · Turkey (Türkiye) (4) · Belgium (3) · China (3) · Greece (3) · Spain (3) · Argentina (2) · Chile (2)
Charalampos Mermigkis, MD (2) · Izolde Bouloukaki, MD, PhD (2) · Sophia E Schiza, MD, PhD (2) · Adriana Aguilar, MD (1) · Alan Morris, MD (1) · Alfred F. Connors, MD (1) · Andrew Wellman, PhD MD (1) · Anne Dixon, BM BCh (1) · Antonio Anzueto, MD (1) · Arjumand Bano, Ms CPPT (1) · Arthur Wheeler, MD (1) · Basak Pehlivan, Asoc Prof (1) · Bon Wook Koo (1) · Brigette Wilkins, Physio (1)
PMID 26225498, PMID 26716862, PMID 11323373, PMID 11435250, PMID 11549535, PMID 11733397, PMID 12456460, PMID 14674978, PMID 15105237, PMID 15189655, PMID 17585106, PMID 18401254, PMID 18853696, PMID 18931236, PMID 19403595, PMID 19926983, PMID 21358846, PMID 21358847, PMID 22473256, PMID 23201585, PMID 23204602, PMID 23211642, PMID 23227139, PMID 23362167, PMID 23386371, PMID 23407019, PMID 24127141, PMID 24634638, PMID 24690329, PMID 24808886, PMID 24910546, PMID 24916094, PMID 25232509, PMID 25624390, PMID 25818272, PMID 26196743, PMID 26518698, PMID 27242272, PMID 27852713, PMID 28194273, PMID 28284473, PMID 28707173, PMID 28899524, PMID 29420341, PMID 29430407, PMID 29444644, PMID 29720277, PMID 3057937, PMID 30612327, PMID 30624279
5UH3HL140177-03 (1), N01HR56165 (1), N01HR56166 (1), N01HR56167 (1), N01HR56168 (1), N01HR56169 (1), N01HR56170 (1), N01HR56171 (1), N01HR56172 (1), N01HR56173 (1), N01HR56174 (1), N01HR56175 (1), N01HR56176 (1), N01HR56179 (1), R01HL036787 (1)