33 completed, 15 unknown, 6 terminated, 5 not yet recruiting. 69 Phase 1, 30 Phase 2.
Follow Intracranial Hemorrhages: new trials by email Literature Review of Intracranial Hemorrhages trials Research Report on Intracranial Hemorrhages
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ventricular mTOR Inhibition to Prevent Hydrocephalus After Brain Hemorrhage Sirolimus (Rapamune®) - Post-hemorrhagic Hydrocephalus (PHH) | Phase 1 / Phase 2 | Not yet recruiting | Massachusetts General Hospital | 15 | 2027-01-01 | 2026-06-25 |
| Intra-Arterial Bevacizumab as an Adjunct to Middle Meningeal Artery Embolization for Chronic Subdural Hematoma Bevacizumab (intra-arterial) - Chronic Subdural Hematoma | Phase 1 | Not yet recruiting | Dheeraj Gandhi | 18 | 2027-01-01 | 2026-07-27 |
| Induced Suppression of Platelet Activity in Aneurysmal Subarachnoid Hemorrhage Management-2 (iSPASM-2) Tirofiban, Placebo - Aneurysmal Subarachnoid Hemorrhage | Phase 1 / Phase 2 | Not yet recruiting | Dr David Hasan, M.D. | 82 | 2026-12-05 | 2026-11-04 |
| Tenecteplase (TNK) in the Treatment of Intracerebral Hemorrhage (ICH) TNK - Intracerebral Hemorrhage, Intracranial Hemorrhages | Phase 1 | Not yet recruiting | Gaurav Gupta, MD | 5 | 2026-09-15 | 2026-04-30 |
| An Open-Label, Dose-Escalation Study on the Safety, Tolerability and Preliminary Efficacy for Preventing SAP by Intravenous Pump-Delivered Propranolol in Patients With ICH Intravenous Pump-Delivered Propranolol - Intracerebral Hemorrhage, Stroke-Associated Pneumonia (SAP) | Phase 1 | Not yet recruiting | Tang-Du Hospital | 30 | 2026-05-01 | 2026-04-14 |
| Tocilizumab-aazg for Hemorrhage: Reduction of Ischemic Vascular Events tocilizumab-aazg (TYENNE) - Aneurysmal Subarachnoid Hemorrhage, Delayed Cerebral Ischemia | Phase 1 | Recruiting | University of Florida | 30 | 2026-03-02 | 2026-09-23 |
| Psychedelic Healing: Adjunct Therapy Harnessing Opened Malleability Psilocybin (Usona Institute) - Stroke, Chronic Stroke | Phase 1 | Recruiting | Johns Hopkins University | 20 | 2026-02-09 | 2026-02-13 |
| Stem Cell Therapy for Intracerebral Hemorrhage Device: Phase Ⅰ Dose Level 1, Device: Phase Ⅰ Dose Level 2, Device: Phase Ⅰ Dose Level 3 - Intracerebral Hemorrhage, Mesenchymal Stem Cell | Phase 1 / Phase 2 | Recruiting | Tang Zhouping | 39 | 2025-06-02 | 2026-10-20 |
| Minimally Invasive Surgery and rhTNK-tPA for Intracerebral Hemorrhage Evacuation Minimally invasive surgery plus low-dose rhTNK-tPA group, Minimally invasive surgery plus medium dose rhTNK-tPA group, Minimally invasive surgery plus high dose rhTNK-tPA group - Intracranial Hemorrhages, Cerebrovascular Disorders | Phase 1 | Completed | Beijing Tiantan Hospital | 12 | 2024-11-04 | 2025-03-07 |
| Chronic Subdural Hematoma Treatment With Intra-Arterial Bevacizumab Injection Bevacizumab 2 mg/kg, Bevacizumab 4 mg/kg - Chronic Subdural Hematoma | Phase 1 | Completed | The Cooper Health System | 10 | 2024-06-17 | 2026-10-02 |
| Intracerebral Transplantation of Autologous MSC Combined With Scaffold Product for Chronic Intracerebral Hemorrhage HUFF-01 - Intracerebral Hemorrhage | Phase 1 / Phase 2 | Active not recruiting | Hokkaido University Hospital | 8 | 2023-12-01 | 2026-10-15 |
| Hyperpolarized 13C-pyruvate Metabolic MRI With Traumatic Brain Injury Hyperpolarized 13C-Pyruvate - Traumatic Brain Injury, Subarachnoid Hemorrhage | Phase 1 | Recruiting | University of Maryland, Baltimore | 15 | 2023-10-26 | 2025-05-11 |
| Fingolimod in Minimal Invasive Treatment of Intracerebral Hemorrhage Fingolimod - Intracerebral Hemorrhage | Phase 1 / Phase 2 | Unknown | Tang-Du Hospital | 40 | 2023-10-11 | 2023-10-18 |
| Minocycline Accelerates Intracerebral Hemorrhage Absorption Minocycline, starch - Intracerebral Hemorrhage | Phase 1 | Unknown | Second Affiliated Hospital, Zhejiang University, School of Medicine | 90 | 2023-01-01 | 2022-11-29 |
| Deferoxamine in Aneurysmal Subarachnoid Hemorrhage Trial Deferoxamine, placebo - Intracranial Aneurysm, Subarachnoid Hemorrhage | Phase 1 / Phase 2 | Unknown | Radboud University Medical Center | 40 | 2022-12-02 | 2023-04-24 |
| Relative Bioavailability of Intravenous GTX-104 Compared to Oral Nimodipine Capsules in Healthy Subjects GTX-104, Nimodipine Capsules - Aneurysmal Subarachnoid Hemorrhage | Phase 1 | Completed | Grace Therapeutics Inc. | 58 | 2021-08-26 | 2023-08-31 |
| Prophylactic Antibiotics Useful With Antibiotic Impregnated External Ventricular Drains (EVDs)? Long term (continuous) prophylactic antibiotics, 24 hours antibiotics - Subarachnoid Hemorrhage, Intracerebral Hemorrhage | Phase 1 | Recruiting | Montefiore Medical Center | 84 | 2021-06-14 | 2026-08-10 |
| Safety and Efficacy Study of Etanercept for Aneurysmal Subarachnoid Hemorrhage Etanercept - Subarachnoid Hemorrhage, Aneurysmal | Phase 1 | Withdrawn | Unity Health Toronto | 2021-01-01 | 2020-11-02 | |
| Efficacy of Percutaneous SPG Block in Aneurysmal SAH Regional anesthetic SPG block-bilateral - Subarachnoid Hemorrhage, Headache | Phase 1 | Completed | Mayo Clinic | 2 | 2020-11-01 | 2024-04-09 |
| A Clinical Trial to Determine the Safety and Efficacy of Hope Biosciences Autologous Mesenchymal Stem Cell Therapy for the Treatment of Traumatic Brain Injury and Hypoxic-Ischemic Encephalopathy HB-adMSCs - Traumatic Brain Injury | Phase 1 / Phase 2 | Completed | Hope Biosciences LLC | 24 | 2020-01-01 | 2026-01-15 |
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Subarachnoid Hemorrhage (32) · Cerebral Hemorrhage (29) · Stroke (12) · Vasospasm, Intracranial (6) · Aneurysm (5) · Brain Injuries, Traumatic (4) · Hemorrhagic Stroke (4) · Ischemic Stroke (4) · Bronchiolitis Obliterans Syndrome (3) · Hemorrhage (3) · Hydrocephalus (3) · Intracranial Aneurysm (3) · Brain Edema (2) · Central Nervous System Diseases (2)
Cardiovascular Diseases (69) · Pathologic Processes (69) · Pathological Conditions, Signs and Symptoms (69) · Brain Diseases (68) · Cerebrovascular Disorders (68) · Nervous System Diseases (68) · Vascular Diseases (68) · Central Nervous System Diseases (67) · Hemorrhage (66) · Wounds and Injuries (8) · Signs and Symptoms (7) · Trauma, Nervous System (6) · Craniocerebral Trauma (5) · Hematoma (4)
Deferoxamine (3) · Minocycline (3) · Saline Solution (3) · Bevacizumab (2) · Dantrolene (2) · EG-1962 (2) · Mannitol (2) · Nimodipine (2) · Simvastatin (2) · Sodium Chloride (2) · Tirofiban (2) · 5-(3-hydroxybenzoyl)-2-thiophenesulfonamide (1) · Acetaminophen (1) · Acupuncture Therapy (1) · Administration, Sublingual (1)
Beijing Tiantan Hospital (2) · Capital Medical University (2) · Edge Therapeutics Inc (2) · Massachusetts General Hospital (2) · Mayo Clinic (2) · Tang-Du Hospital (2) · Thomas Jefferson University (2) · University of Massachusetts, Worcester (2) · Washington University School of Medicine (2) · AegisCN LLC (1) · Augusta University (1) · Baylor College of Medicine (1) · Beth Israel Deaconess Medical Center (1) · Brigham and Women's Hospital (1) · CellMed AG, a subsidiary of BTG plc. (1)
United States (40) · China (9) · Canada (6) · Finland (2) · Germany (2) · Czechia (1) · Israel (1) · Japan (1) · Netherlands (1) · Poland (1) · Spain (1) · Taiwan (1) · United Kingdom (1)
Michael Diringer, MD (2) · Susanne Muehlschlegel, MD (2) · Abba C Zubair (1) · Abbot R. Laptook, MD (1) · Abhik Das, PhD (1) · Adnan I. Qureshi, MD (1) · Ajith J Thomas, MD (1) · Andrew Baker, MD (1) · Barbara J. Stoll, MD (1) · Boguslaw Machalinski, MD, PhD, BSc (1) · Brenda B. Poindexter, MD MS (1) · Brian Hoh, MD (1) · Brian Mac Grory, MD (1) · Brian P Walcott, MD (1) · Brian V Nahed, MD (1)
PMID 30739747, PMID 16319269, PMID 18606927, PMID 18658043, PMID 19236490, PMID 19628806, PMID 19770736, PMID 20457956, PMID 21396235, PMID 21454813, PMID 21626077, PMID 22560810, PMID 22989500, PMID 23233387, PMID 24218460, PMID 25072112, PMID 25148012, PMID 25344064, PMID 25549192, PMID 25678453, PMID 26067213, PMID 26409481, PMID 26643677, PMID 26721259, PMID 27932607, PMID 28101148, PMID 28887388, PMID 28928910, PMID 29871521, PMID 30355183, PMID 30428930, PMID 31775069, PMID 31812149, PMID 31900351, PMID 32253717, PMID 32384763, PMID 32391156, PMID 32411082, PMID 32985652, PMID 33236783, PMID 33272131, PMID 33739197, PMID 33841103, PMID 34083595, PMID 34470496, PMID 34873674, PMID 35562205, PMID 35765072, PMID 35769327, PMID 35920945
2015 (1), R01NS044976 (1), R01NS057127 (1), R01NS066929 (1), R44NS071657 (1), U10HD021364 (1), U10HD021373 (1), U10HD021385 (1), U10HD027851 (1), U10HD027856 (1), U10HD027871 (1), U10HD027880 (1), U10HD027904 (1), U10HD034216 (1), U10HD036790 (1)