28 completed, 20 unknown, 14 terminated, 6 recruiting. 29 Not applicable, 17 Phase 2, 7 Phase 1, 6 Phase 3, 4 Phase 4.
Follow Vasospasm, Intracranial: new trials by email Literature Review of Vasospasm, Intracranial trials Research Report on Vasospasm, Intracranial
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effect of Sympathetic Modulation on Cerebral Vasospasm Secondary to Aneurysmal Subarachnoid Hemorrhage Vectris trial leads and stimulation, Sham - Vasospasm, Cerebral, Aneurysmal Subarachnoid Hemorrhage | Not applicable | Suspended | University of Alabama at Birmingham | 25 | 2028-07-31 | 2026-09-24 |
| Noninvasive CA Monitoring Validation and Autonomic Modulation in Aneurysmal Subarachnoid Hemorrhage Right-Sided Cervical Sympathetic Block at C6, Transcutaneous Auricular Vagal Nerve Stimulation (taVNS) - Subarachnoid Hemorrhage, Aneurysmal, Delayed Cerebral Ischemia | Not applicable | Not yet recruiting | University of Texas Southwestern Medical Center | 300 | 2027-07-01 | 2026-10-16 |
| Endovascular Therapy for Cerebral Vasospasm After Aneurysmal Subarachnoid Hemorrhage Intra-arterial and Intravenous Milrinone Therapy, Standardized Medical Management - Subarachnoid Hemorrhage, Aneurysmal, Cerebral Vasospasm After Subarachnoid Hemorrhage | Not applicable | Not yet recruiting | Beijing Tiantan Hospital | 306 | 2026-10-01 | 2026-09-23 |
| The Effect of Transcutaneous Vagal Nerve Stimulation (tVNS) on Cerebral Vasospasm Secondary to Aneurysmal Subarachnoid Hemorrhage Transcutaneous Vagal Nerve Stimulation - Aneurysmal Subarachnoid Hemorrhage, Vasospasm, Cerebral | Not applicable | Recruiting | Marshall Holland | 10 | 2026-02-06 | 2026-08-11 |
| Registry on NeVa VS for CerebraL VAsospasm ManagemenT in Post SAH PatiEnts NEVA VS - Cerebral Vasospasm, Aneurysmal Subarachnoid Hemorrhage (aSAH) | Recruiting | Vesalio | 200 | 2025-04-14 | 2026-05-27 | |
| Incidence, Characteristics and Evolution of Cerebral Vasospasm With Clinical Impact in Moderate to Severe Traumatic Brain Injury Complicated by Subarachnoid Hemorrhage at Martinique University Hospital Additional realization of a brain perfusion scan sequence which would allow the radiological diagnosis of CV - SAH (Subarachnoid Hemorrhage), Cerebral Vasospasm | Not applicable | Recruiting | University Hospital Center of Martinique | 154 | 2024-11-06 | 2025-03-31 |
| Mechanical Intracranial Artery DilAtation Using Stent-retriever for Cerebral Vasospasm stent-angioplasty & nimodipine infusion (During the stent (Solitaire-X) -angioplasty, IA nimodipine was also infused) - Intracranial Vasospasm | Not applicable | Not yet recruiting | Yonsei University | 10 | 2024-09-01 | 2024-09-27 |
| Mechanisms of Brain-Heart Injury of Post-Intracranial Hemorrhage Multi-disciplinary assessment - Subarachnoid Hemorrhage, Aneurysmal, Cerebrocardiac Syndrome | Recruiting | Beijing Tiantan Hospital | 1000 | 2024-08-01 | 2025-04-02 | |
| Predictive Model for the Occurrence of Cerebral Vasospasm Complicating Subarachnoid Haemorrhage by Combined Analysis of the Kinetics of a Panel of Biomarkers. Samples collection - Cerebral Vasospasm | Not applicable | Completed | University Hospital, Bordeaux | 155 | 2024-05-07 | 2025-08-06 |
| Nitric Oxide Consumption as a Predictor of Vasospasm in Subarachnoid Hemorrhage Aneurysmal Subarachnoid Hemorrhage, Cerebral Vasospasm | Recruiting | Massachusetts General Hospital | 40 | 2024-03-03 | 2026-05-29 | |
| Cervical Sympathetic Block in Patients With Cerebral Vasospasm Cervical sympathetic block - Anesthesia, Local, Cerebral Vasospasm | Not applicable | Enrolling by invitation | Stanford University | 10 | 2023-07-27 | 2025-10-20 |
| Cervical Spinal Cord Stimulation in Patients With Cerebral Vasospasm After Subarachnoid Haemorrhage: VasoStim Study Spinal cord stimulation - Cerebral Vasospasm, Subarachnoid Hemorrhage | Not applicable | Terminated | Insel Gruppe AG, University Hospital Bern | 1 | 2023-06-30 | 2026-01-08 |
| Magnesium Treating Subarachnoid Hemorrhage Vasospasm Magnesium sulfate, normal saline - Subarachnoid Hemorrhage, Aneurysmal, Cerebral Vasospasm | Phase 2 / Phase 3 | Unknown | General Committee of Teaching Hospitals and Institutes, Egypt | 200 | 2022-12-01 | 2022-09-13 |
| Chemical and Mechanical Angioplasty for Vasospasm (SAVEBRAIN) Chemical and Mechanical Angioplasty for Refractory Intracranial Arterial Vasospastic Stenosis - Aneurysmal Subarachnoid Hemorrhage, Vasospasm, Intracranial | Not applicable | Completed | Erasme University Hospital | 22 | 2022-03-01 | 2024-02-21 |
| Angiotensin Metabolite Profile After Subarachnoid Hemorrhage Sampling of plasma and cerebrospinal fluid at specified time points - Subarachnoid Hemorrhage, Aneurysmal | Unknown | Dr. Roman Ullrich | 60 | 2022-03-01 | 2022-03-02 | |
| Epigenome-wide DNA Methylation Profiling in Aneurysmal Subarachnoid Hemorrhage and Delayed Ischemic Neurologic Deficit Subarachnoid Hemorrhage, Aneurysmal, Delayed Cerebral Ischemia | Active not recruiting | Pomeranian Medical University Szczecin | 61 | 2021-12-20 | 2025-07-31 | |
| "The Effect of Stellate Ganglion Block in Severe Brain Injury" one site blockade of the stellate ganglion - Traumatic Brain Injury, Brain Inflammation | Not applicable | Completed | University Medical Centre Ljubljana | 40 | 2021-11-01 | 2024-01-03 |
| Early Warning of Delayed Cerebral Ischemia Computed Tomography (CT) and Computed Tomography Angiography (CTA), Multimodal physiological monitoring - Subarachnoid Hemorrhage, Aneurysmal, Vasospasm, Cerebral | Unknown | Vilnius University | 250 | 2021-09-21 | 2023-09-06 | |
| Stellate Ganglion Block and Cerebral Vasospasm Stellate ganglion block - Aneurysmal Subarachnoid Hemorrhage, Stellate Ganglion Block | Not applicable | Unknown | Beijing Tiantan Hospital | 202 | 2021-07-01 | 2024-03-15 |
| Cerebral Nimodipine Concentrations Following Oral, Intra-venous and Intra-arterial Administration Nimodipine - Subarachnoid Hemorrhage, Aneurysmal, Delayed Cerebral Ischemia | Unknown | Medical University of Vienna | 30 | 2020-11-25 | 2023-10-19 |
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Subarachnoid Hemorrhage (70) · Aneurysm (11) · Intracranial Aneurysm (10) · Hydrocephalus (6) · Brain Ischemia (4) · Aneurysm, Ruptured (3) · Brain Injuries, Traumatic (2) · Stroke (2) · Arrhythmias, Cardiac (1) · Arteriovenous Fistula (1) · Atrial Fibrillation (1) · Autonomic Nervous System Diseases (1) · Brain Injuries (1) · Brain Neoplasms (1)
Brain Diseases (81) · Cardiovascular Diseases (81) · Central Nervous System Diseases (81) · Cerebrovascular Disorders (81) · Nervous System Diseases (81) · Vascular Diseases (81) · Pathological Conditions, Signs and Symptoms (72) · Pathologic Processes (71) · Hemorrhage (70) · Intracranial Hemorrhages (70) · Intracranial Arterial Diseases (11) · Aneurysm (10) · Craniocerebral Trauma (3) · Trauma, Nervous System (3) · Wounds and Injuries (3)
Ultrasonography, Doppler, Transcranial (4) · Sildenafil Citrate (3) · clazosentan (3) · Nicardipine (2) · Nimodipine (2) · Saline Solution (2) · Spinal Cord Stimulation (2) · 5-(3-hydroxybenzoyl)-2-thiophenesulfonamide (1) · Acetaminophen (1) · Acetazolamide (1) · Acetylcysteine (1) · Acupuncture Therapy (1) · Administration, Cutaneous (1) · Aluminum Hydroxide (1) · Anesthesia, Local (1)
Beijing Tiantan Hospital (4) · Idorsia Pharmaceuticals Ltd. (3) · HeadSense Medical (2) · Henry Ford Health System (2) · State University of New York - Upstate Medical University (2) · University of Wisconsin, Madison (2) · Vesalio (2) · Assiut University (1) · Baylor College of Medicine (1) · Charite University, Berlin, Germany (1) · Dr. Roman Ullrich (1) · El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez (1) · Elisabeth-TweeSteden Ziekenhuis (1) · Erasme University Hospital (1) · General Committee of Teaching Hospitals and Institutes, Egypt (1)
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Eric M Deshaies, MD (2) · Adrien Guenego, MD (1) · Afaf A. Hasan, Profosser (1) · Ali Alaraj, MD (1) · Angelika G Sorteberg, MD, PhD (1) · Angelina Marr, BSc. Pharm (1) · Anna Maria Bombardieri, MD, PhD (1) · Atahualpa Caue Strapasson, MD (1) · Azam Ahmed, MD (1) · Ben Z. Roitberg, MD (1) · Bobby M Agrawal, MD (1) · Boyd Richards, DO (1)
PMID 10525849, PMID 10563118, PMID 10717509, PMID 10825515, PMID 10978043, PMID 11452854, PMID 11563280, PMID 11846914, PMID 12568169, PMID 13933363, PMID 15018324, PMID 15508346, PMID 15526491, PMID 1580013, PMID 15898439, PMID 16418351, PMID 1704491, PMID 18239182, PMID 18245071, PMID 18356250, PMID 18456995, PMID 1866764, PMID 18839484, PMID 18850093, PMID 19625911, PMID 19847758, PMID 21125452, PMID 2181766, PMID 21917146, PMID 21998061, PMID 22267829, PMID 22368972, PMID 22403047, PMID 22678087, PMID 22700527, PMID 2295920, PMID 23032083, PMID 23328469, PMID 23581590, PMID 24425125, PMID 25072112, PMID 25280913, PMID 25344064, PMID 25366638, PMID 25886483, PMID 26248048, PMID 26428322, PMID 26495942, PMID 27000643, PMID 27737684
2015 (1), P50GM015431 (1), R01NS049135 (1)