16 completed, 4 unknown, 3 recruiting, 3 terminated. 10 Phase 2, 7 Phase 4, 5 Not applicable, 5 Phase 1, 3 Early Phase 1.
Follow Nimodipine: new trials by email Literature Review of Nimodipine trials Research Report on Nimodipine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Nimodipine on Alcohol Drinking Nimodipine, Placebo - Alcohol Use Disorder | Phase 2 | Not yet recruiting | Yale University | 40 | 2026-09-01 | 2026-07-02 |
| Pilot Study: Effects of Nimodipine on Alcohol Drinking Nimodipine - Alcohol Use Disorder | Phase 2 | Not yet recruiting | Yale University | 5 | 2026-09-01 | 2026-03-17 |
| NICardipine for Fast Achievement of Systolic BP Targets in ICH Nicardipine, Glyceryl trinitrate - Intracerebral Haemorrhage | Phase 4 | Recruiting | Aarhus University Hospital | 88 | 2025-10-01 | 2026-06-24 |
| Perioperative Intravenous Nimodipine Trial Nimodipine, Isotonic Saline - Colectomy, Open Surgery | Not applicable | Recruiting | University of Ioannina | 40 | 2025-05-19 | 2026-09-14 |
| A Causal Role for Voltage-gated Cav1.2 Calcium Channels in Mediating 5G FR1 Effects on Sleep-associated Brain Health in Humans Nimodipine Capsules, 5G RF-EMF - Mediation of 5G Effects on Sleep | Not applicable | Recruiting | Hans-Peter Landolt | 30 | 2024-10-22 | 2025-05-31 |
| Safety and Tolerability of GTX-104 Compared with Oral Nimodipine in Patients with ASAH GTX-104, Nimotop 30 MG Oral Capsule - Aneurysmal Subarachnoid Hemorrhage (aSAH) | Phase 3 | Active not recruiting | Grace Therapeutics Inc. | 100 | 2023-10-20 | 2024-10-01 |
| Management of Cerebral Vascular Spasm in Posttraumatic Subarachnoid Hemorrhage Using Combination Therapy nimodipine, Oral Nimodipine and milrinone - Oral Nimodipine, Milrinone | Phase 2 | Completed | Zagazig University | 30 | 2021-11-24 | 2022-05-25 |
| Relative Bioavailability of Intravenous GTX-104 Compared to Oral Nimodipine Capsules in Healthy Subjects GTX-104, Nimodipine Capsules - Aneurysmal Subarachnoid Hemorrhage | Phase 1 | Completed | Grace Therapeutics Inc. | 58 | 2021-08-26 | 2023-08-31 |
| Pharmacological Mechanisms of Low-intensity Focused Ultrasound for Motor Cortex Neuroplasticity Carbamazepine, Lorazepam, Dextromethorphan - Low Intensity Focussed Ultrasound | Early Phase 1 | Active not recruiting | University Health Network, Toronto | 20 | 2021-05-25 | 2025-08-03 |
| Cerebral Nimodipine Concentrations Following Oral, Intra-venous and Intra-arterial Administration Nimodipine - Subarachnoid Hemorrhage, Aneurysmal, Delayed Cerebral Ischemia | Unknown | Medical University of Vienna | 30 | 2020-11-25 | 2023-10-19 | |
| Effectiveness of Calcium Channel Blockade for OP and Carbamate Pesticide Poisoning Magnesium Sulfate, Nimodipine - Anticholinesterase Insecticide Poisoning, Pesticide Poisoning | Phase 3 | Completed | University of Edinburgh | 1728 | 2020-06-11 | 2025-10-01 |
| Coronavirus (COVID-19) ACEi/ARB Investigation Thiazide or Thiazide-like diuretics, Calcium Channel Blockers, ACE inhibitor - Hypertension, COVID-19 | Phase 4 | Suspended | National University of Ireland, Galway, Ireland | 2414 | 2020-04-30 | 2020-06-30 |
| Stellate Ganglion Block as Adjuvant Therapy to ca Channel Blocker stellate ganglion block by transcranial doppler, Nimodipine - Subarachnoid Hemorrhage | Phase 2 | Completed | Assiut University | 40 | 2020-01-11 | 2023-06-13 |
| Measuring Blood Flow in the Brain After Epileptic Activity Paracetamol, Nimotop - Epilepsy, Depression | Phase 2 | Completed | Rijnstate Hospital | 34 | 2019-12-05 | 2023-11-18 |
| Cognitive Effects of Nimodipine in Patients With Schizophrenia Nimodipine, Placebo oral capsule - Schizophrenia, Schizo Affective Disorder | Early Phase 1 | Completed | Johns Hopkins University | 18 | 2018-10-05 | 2023-06-23 |
| Bioavailability Comparison Study of Two Types of Nimodipine Injections in Healthy Volunteers Nimodipine Injection, Nimodipine Injection (II) - Bioavailability, Safety Issues | Early Phase 1 | Unknown | Shenyang Dongxing Pharmaceutical Technology Co., Ltd. | 26 | 2018-08-23 | 2019-01-08 |
| RCVS: The Rational Approach to Diagnosis and Treatment TCD- cerebral blood flow velocities, Headache pain score, Neurological examination - Reversible Cerebral Vasoconstriction Syndrome | Phase 4 | Withdrawn | Johns Hopkins University | 2017-07-01 | 2019-09-18 | |
| Noninvasive Assessment of Cerebral Oxygenation and Cardiac Function in Patients With Neurovascular Diseases Nimodipine - Subarachnoid Hemorrhage, Aneurysmal | Completed | National Institute of Mental Health and Neuro Sciences, India | 25 | 2016-12-01 | 2019-03-26 | |
| The Effect of Nimodipine on the Postoperative Cognitive Dysfunction Nimodipine group, Control group - Mild Cognitive Impairment | Not applicable | Terminated | University Hospital Hradec Kralove | 15 | 2015-09-01 | 2019-10-01 |
| Carbonic Anhydrase Antagonism in Subarachnoid Hemorrhage Acetazolamide, Nimodipine - Acute Cerebrovascular Accident, Vasospasm | Phase 2 | Withdrawn | University of Florida | 2015-09-01 | 2015-09-24 |
Showing 20 of 34. Sign in to see all of them.
Subarachnoid Hemorrhage (8) · Stroke (3) · Alcoholism (2) · Cocaine-Related Disorders (2) · Cognitive Dysfunction (2) · Depression (2) · Hypertension (2) · Vasospasm, Intracranial (2) · AIDS Dementia Complex (1) · AIDS-Related Complex (1) · Acquired Immunodeficiency Syndrome (1) · Acute Pain (1) · Anovulation (1) · COVID-19 (1) · Cardiovascular Diseases (1)
Yale University (3) · Grace Therapeutics Inc. (2) · Johns Hopkins University (2) · Aarhus University Hospital (1) · Assiut University (1) · Boston IVF (1) · Edge Therapeutics Inc (1) · FDA Office of Orphan Products Development (1) · Fengtian Hospital (1) · Hans-Peter Landolt (1) · Janssen-Cilag Farmaceutica Ltda. (1) · Medical University of Vienna (1) · Ministry of Science and Technology of the People´s Republic of China (1) · Mount Sinai Hospital, Canada (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1)
United States (12) · Canada (4) · China (4) · Czechia (2) · Egypt (2) · Austria (1) · Bangladesh (1) · Denmark (1) · Finland (1) · Greece (1) · India (1) · Ireland (1) · Netherlands (1) · Switzerland (1)
Suchitra Krishnan-Sarin (2) · Adam Boxer, MD, PhD (1) · Alan S Penzias, MD (1) · Daniel Hanggi (1) · Dr Fazle Rabbi Chowdhury, MD (1) · Elisabeth B Marsh, MD (1) · Ellen M. Whyte, MD (1) · Eric Sicard, MD (1) · Jeroen A van Waarde, MD (1) · John William McEvoy, MBBCh MHS (1) · Kristin Bigos, PhD (1) · Lipton S (1) · Michael Anthony Belfort (1) · Navia B (1)
PMID 24964105, PMID 25678453, PMID 27932607, PMID 31812149, PMID 35436940, PMID 36659633, PMID 39560199, PMID 39875683, PMID 40659830
P50AA012870 (2), K23MH067710 (1), P50DA009250 (1)