145 unknown. 145 Phase 2, 30 Phase 3, 27 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 145 | Unknown 145 |
| Phase 3 | 30 | Unknown 30 |
| Phase 1 | 27 | Unknown 27 |
Follow Inflammation: new trials by email Literature Review of Inflammation trials Research Report on Inflammation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Comparative Study Between Dexmedetomidine Versus Methylprednisolone on Induced Inflammatory Response in Patients Undergoing On-pump CABG Normal saline, Dexmedetomidine, Methylprednisolone - Coronary Artery Disease, Systemic Inflammatory Response Syndrome | Phase 1 / Phase 2 | Unknown | Ain Shams University | 60 | 2025-09-01 | 2025-08-06 |
| Investigation of Novel and Established Therapies in a Human Intravenous Lipopolysaccharide Model of Sepsis Imatinib, Compound sodium lactate solution - Sepsis, Fluid Overload | Phase 1 / Phase 2 | Unknown | Belfast Health and Social Care Trust | 65 | 2024-12-01 | 2024-10-04 |
| MRG-001 as an Immunoregulatory and Regenerative Therapy for ARDS Patients MRG-001 (Low-dose), MRG-001 (High-dose), Placebo - Acute Respiratory Distress Syndrome, Respiratory Failure | Phase 2 | Unknown | MedRegen LLC | 60 | 2024-12-01 | 2024-08-23 |
| Cilostazol in Parkinson's Disease Cilostazol, Placebo, Standard treatment - Parkinson's Disease | Phase 2 | Unknown | Ain Shams University | 50 | 2024-10-01 | 2024-09-25 |
| Black Seed Oil in ADHD Atomoxetine, Black Seed Oil Cap/Tab - ADHD | Phase 2 | Unknown | Ain Shams University | 60 | 2024-10-01 | 2024-08-09 |
| Beta-Hydroxybutyrate Feasibility Treating IBD Feasibility of beta-hydroxybutyrate supplementation to reduce inflammation in patients with Crohn's - Crohn's Disease, Inflammatory Bowel Diseases | Phase 1 / Phase 2 | Unknown | University of Texas at Austin | 20 | 2024-08-28 | 2024-09-19 |
| Early Resuscitation in Paediatric Sepsis Using Inotropes Fluid, Adrenalin - Sepsis | Phase 2 | Unknown | NATALIA LOPERA MUNERA | 40 | 2024-07-01 | 2024-06-27 |
| Dexmedetomidine and Vasopressin in Septic Shock DEX-PRESSIN, Standard of Care - Sepsis, Septic Shock | Phase 2 | Unknown | Mansoura University | 260 | 2024-06-01 | 2024-03-12 |
| Role of Active Deresuscitation After Resuscitation: Furosemide Injection, Metolazone Tablets - Fluid Overload, Critical Illness | Phase 2 | Unknown | Unity Health Toronto | 120 | 2024-05-01 | 2024-03-22 |
| Metformin and Lactoferrin in Sepsis in Icu Metformin, Lactoferrin - Sepsis | Phase 2 / Phase 3 | Unknown | Tanta University | 60 | 2024-04-01 | 2024-04-19 |
| Reversing Microvascular Dysfunction in Heart Failure With Preserved Ejection Fraction Colchicine, Placebo - Heart Failure With Preserved Ejection Fraction, Microvascular Coronary Artery Disease | Phase 2 / Phase 3 | Unknown | Montreal Heart Institute | 60 | 2024-03-01 | 2024-01-25 |
| Use of Dobutamine in Patients With Sepsis and Maintained Hypoperfusion After Initial Volemic Resuscitation. Dobutamine - Sepsis, Hypoperfusion | Phase 2 | Unknown | Federal University of São Paulo | 120 | 2024-02-01 | 2024-01-30 |
| The COLchicine HEART Failure PRESERVED Trial (COLHEART-PRESERVED) Colchicine, Placebo - Heart Failure With Preserved Ejection Fraction | Phase 2 | Unknown | Tor Biering-Sørensen | 152 | 2024-01-18 | 2024-02-28 |
| Effectiveness of Asiaticoside as Intracanal Medication on Infectious/Inflammatory Contents in Teeth With Apical Periodontitis Calcium Hydroxide Intracanal medication, Leddermix Intracanal medication, Asiaticoside Intracanal medication - Intracanal Medication | Phase 2 / Phase 3 | Unknown | Mansoura University | 36 | 2023-11-20 | 2024-08-22 |
| A Multicenter, Randomized, Double-blind, Placebo-controlled Phase II Dose Exploration Clinical Trial Evaluating the Efficacy, Safety, and Pharmacokinetic Characteristics of STC314 Injection Administered Intravenously in Sepsis Patients STC314 Injection/STC314 Injection Placebo - Sepsis | Phase 2 | Unknown | Grand Medical Pty Ltd. | 180 | 2023-11-20 | 2024-08-12 |
| Early Versus Conventional Cessation of Hydrocortisone in Septic Shock normal saline solution, Hydrocortisone and normal saline solution - Septic Shock, Adverse Event | Phase 2 | Unknown | Mahidol University | 160 | 2023-07-05 | 2024-04-05 |
| Beta-glucans for Hospitalised Patients With COVID-19 MC 3x3, Placebo - COVID-19 | Phase 2 | Unknown | Wohlstand Pharmaceutical | 60 | 2023-06-01 | 2022-12-13 |
| Efficacy and Safety of corticoSTEROids Added to Standard Therapy in Patients With Acute Heart Failure (STERO-AHF) Dexamethasone, Prednisone - Acute Heart Failure | Phase 2 / Phase 3 | Unknown | Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia | 120 | 2023-04-24 | 2023-12-04 |
| Alpha-Lipoic Acid in Patients With Sepsis Alpha-Lipoic Acid, Sepsis Supportive Care - Sepsis | Phase 2 / Phase 3 | Unknown | Ain Shams University | 60 | 2023-03-10 | 2023-04-12 |
| Dexmedetomidine and HIPEC Dexmedetomidine, Placebos - Inflammation, Cancer | Phase 2 / Phase 3 | Unknown | University of British Columbia | 20 | 2023-03-01 | 2022-11-03 |
Showing 20 of 145. Sign in to see all of them.
Sepsis (42) · Shock, Septic (26) · COVID-19 (13) · Cytokine Release Syndrome (12) · Atherosclerosis (6) · Insulin Resistance (6) · Systemic Inflammatory Response Syndrome (6) · Neuroinflammatory Diseases (5) · Respiratory Distress Syndrome (5) · Shock (5) · Bacteremia (4) · Diabetes Mellitus (4) · Diabetes Mellitus, Type 2 (4) · Acute Kidney Injury (3)
Pathological Conditions, Signs and Symptoms (145) · Pathologic Processes (143) · Infections (75) · Systemic Inflammatory Response Syndrome (69) · Shock (39) · Respiratory Tract Diseases (26) · Lung Diseases (25) · Cardiovascular Diseases (20) · Vascular Diseases (19) · Sepsis (18) · Nutritional and Metabolic Diseases (17) · RNA Virus Infections (16) · Respiratory Tract Infections (16) · Nervous System Diseases (15)
Saline Solution (6) · esmolol (4) · Colchicine (3) · Docosahexaenoic Acids (3) · Terlipressin (3) · Angiotensin II (2) · Ascorbic Acid (2) · Control Groups (2) · Dexamethasone (2) · Dexmedetomidine (2) · Dobutamine (2) · Hydrocortisone (2) · Interleukin 1 Receptor Antagonist Protein (2) · Lactoferrin (2) · Meropenem (2)
Ain Shams University (6) · University of British Columbia (4) · University of Sao Paulo General Hospital (4) · Mahidol University (3) · Azienda Ospedaliera di Padova (2) · Dascena (2) · Fast Forward Pharmaceuticals (2) · Leiden University Medical Center (2) · Mansoura University (2) · Oslo University Hospital (2) · Radboud University Medical Center (2) · 101 Therapeutics (1) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Assaf-Harofeh Medical Center (1) · Assistance Publique - Hôpitaux de Paris (1)
United States (20) · China (14) · Brazil (10) · Egypt (9) · Canada (8) · Netherlands (7) · Italy (6) · Mexico (5) · Indonesia (4) · United Kingdom (4) · Australia (3) · France (3) · Germany (3) · Iran (3) · Israel (3)
Agung Putra, Assoc.Prof (1) · Alaa Hemida (1) · Alejandra Correa, MD (1) · Alexander J Clark, MD, FRCPC (1) · Alfredo R Zarate, MD (1) · Amalia Pinguello, MD (1) · Amany Bader, prof (1) · Antoine Kimmoun, MD (1) · Arash Shirvani, MD, PhD (1) · Bambang Darwono, Dr.Sp.OT (1) · Beata Banaszewska (1) · Bianca Gutfilen, PhD (1) · Bruno Levy, MD PhD (1)
PMID 10415784, PMID 11402097, PMID 12563677, PMID 12628952, PMID 1342820, PMID 14719037, PMID 15030944, PMID 15234492, PMID 15663512, PMID 16164444, PMID 17181919, PMID 17662768, PMID 18003941, PMID 18097874, PMID 18289548, PMID 18289791, PMID 18546285, PMID 19056593, PMID 19105791, PMID 19397687, PMID 19453649, PMID 19998041, PMID 20084502, PMID 20920189, PMID 21131395, PMID 21187189, PMID 21458008, PMID 21638157, PMID 22028728, PMID 22465313, PMID 22545014, PMID 22666356, PMID 22731679, PMID 22985725, PMID 23327349, PMID 23509945, PMID 23562296, PMID 23612995, PMID 23782971, PMID 24641437, PMID 24675228, PMID 25104975, PMID 25378457, PMID 25469528, PMID 25511715, PMID 25634565, PMID 25986785, PMID 26431839, PMID 26545141, PMID 26866499
2015 (2), 2008 (1), 2014 (1), 2018 (1), K08HD052885 (1), R01HD068712 (1), R33AT009991 (1), R44AA030000 (1), R44DK059062 (1)