45 completed, 27 unknown, 4 terminated, 3 recruiting. 27 Not applicable, 19 Phase 2, 19 Phase 4, 17 Phase 3, 2 Phase 1.
Follow Terlipressin: new trials by email Literature Review of Terlipressin trials Research Report on Terlipressin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Terlipressin vs. Somatostatin in Cirrhotic Patients With Acute Variceal Bleeding and Renal Dysfunction 2-4 mg of terlipressin, 3 mg of somatostatin - Liver Cirrhosis | Not applicable | Not yet recruiting | General Hospital of Shenyang Military Region | 64 | 2026-09-25 | 2026-08-27 |
| Terlipressin vs Placebo to Reduce Bleeding in Fibroid Surgery terlipressin (vasoconstrictor), Placebo - Uterine Fibroids (Leiomyoma), Uterine Myoma | Not applicable | Not yet recruiting | Sevil Cankaya | 80 | 2026-08-01 | 2026-08-05 |
| Effects of Terlipressin and Somatostatin on Portal Pressure in Patients Undergoing Living Donor Liver Transplantation Somatostatin, Terlipressin - Liver Transplantation, Portal Hypertension | Not applicable | Recruiting | Istanbul Medipol University Hospital | 50 | 2025-12-29 | 2026-04-29 |
| Comparison of Terlipressin Versus Octreotide in Patients With Hepatorenal Syndrome terlipressin, Octreotide (drug) - Hepatorenal Syndrome | Not applicable | Completed | Lahore General Hospital | 60 | 2025-05-01 | 2026-03-10 |
| Effect of Terlipressin for Intraoperative Blood Pressure Management in Kidney Transplantation terlipressin, Placebo (Normal Saline) - Kidney Transplant, Delayed Graft Function | Not applicable | Active not recruiting | Beijing Friendship Hospital | 150 | 2025-03-06 | 2026-07-13 |
| Safety and Efficacy of Continuous Infusion of Terlipressin With Norepinephrine Versus Norepinephrine Alone in Improving Outcomes of Acute Kidney Injury in Acute on Chronic Liver Failure With Septic Shock Terlipressin, Norephrine - Acute on Chronic Liver Failure | Not applicable | Unknown | Institute of Liver and Biliary Sciences, India | 126 | 2024-08-15 | 2024-08-16 |
| Continuous Versus Bolus Infusion of Terlipressin for Portal Hypertension Related Bleeding in Liver Cirrhosis Terlipressin - Liver Cirrhosis, Portal Hypertension | Not applicable | Unknown | General Hospital of Shenyang Military Region | 40 | 2024-07-01 | 2024-02-23 |
| Endothelin Receptor Antagonism With Ambrisentan to Treat Hepatorenal Syndrome Ambrisentan, Terlipressin - Hepatorenal Syndrome, Liver Cirrhosis | Phase 2 | Active not recruiting | Noorik Biopharmaceuticals AG | 54 | 2024-04-17 | 2026-04-13 |
| Intraoperative Continuous Terlipressin Infusion is Associated With Reduced Severe Postoperative Complications After Laparoscopic Hepatectomy: a Prospective Propensity Score-matched Cohort Study terlipressin - Liver Neoplasms, Postoperative Complications | Completed | First Affiliated Hospital, Sun Yat-Sen University | 161 | 2024-04-01 | 2026-07-28 | |
| Terlipressin in Combined Hepatorenal Syndrome in Patients With Signs of Chronic Renal Disease terlipressin or noradrenalin plus albumin - Liver Cirrhosis, Hepato-Renal Syndrome | Completed | University Hospital Freiburg | 490 | 2024-03-03 | 2025-12-05 | |
| Effect of Terlipressin on the Incidence of Early Postoperative Acute Kidney Injury in Liver Transplantation Patients Terlipressin, normal saline - Acute Kidney Injury, Liver Transplant; Complications | Phase 4 | Completed | Beijing Tsinghua Chang Gung Hospital | 104 | 2023-10-25 | 2026-10-13 |
| Efficacy of Continuous Terlipressin Therapy After Endoscopic Variceal Ligation Terlipressin, 0.9% normal saline (NS) - Variceal Hemorrhage | Phase 3 | Unknown | Post Graduate Institute of Medical Education and Research, Chandigarh | 165 | 2023-09-01 | 2023-09-07 |
| Study to Evaluate R2R01 Plus Terlipressin Versus Terlipressin Alone in Patients With Hepatorenal Syndrome R2R01, Terlipressin - Hepatorenal Syndrome, Acute Kidney Injury | Phase 2 | Unknown | River 2 Renal Corp. | 95 | 2023-06-30 | 2023-10-03 |
| Methods Decreasing Bleeding in Open Myomectomy Misoprostol, Tourniquet, Carbetocin - Misoprostol Allergy, Oxytocin Allergy | Phase 4 | Unknown | Cairo University | 105 | 2023-03-15 | 2023-04-10 |
| Noradrenaline Versus Glypressin for Prevention of Hypotension After Deflation of Tourniquet in Knee Arthroplasty Saline, Norepinephrine, glypressin - Norepinephrine, Glypressin, Tourniquet Deflation, Hypotension | Not applicable | Completed | Tanta University | 135 | 2022-12-01 | 2023-11-22 |
| HRS-AKI Treatment With TIPS in Patients With Cirrhosis TIPS, Standard of Care - Cirrhosis, Liver, Hepatorenal Syndrome | Not applicable | Recruiting | Jena University Hospital | 124 | 2022-11-29 | 2024-11-18 |
| Clinical Trial Comparing Noradrenaline (NA) Plus Placebo Versus Noradrenaline Plus Terlipressin (TP) in Septic Shock Noradrenaline plus Terlipressin - Septic Shock | Phase 3 | Unknown | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | 152 | 2022-10-11 | 2023-04-27 |
| Efficacy and Safety of Vasopressin Versus Terlipressin as a Second Vasopressor in Critically Ill Cirrhotics With Septic Shock- the VITEL-C Trial Terlipressin, vasopressin - Septic Shock, Cirrhosis, Liver | Not applicable | Unknown | Institute of Liver and Biliary Sciences, India | 100 | 2022-04-05 | 2022-04-07 |
| ACid Tranexamic or Terlipressin for Initial Emergency Treatment of Mild to seVere hEmoptysis: a Randomized Trial. Tranexamic Acid 500 MG, Terlipressin, Placebo - Hemoptysis | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 315 | 2022-03-27 | 2026-04-23 |
| The Effect of Intramyometrial Injection of Terlipressin Versus Intramyometrial Injection of Carbitocin on Hemoglobin and Blood Loss During Laparoscopic Myomectomy Operations Terlipressin - Laparoscopic Myomectomy | Not applicable | Unknown | Wael Elbanna Clinic | 99 | 2022-02-27 | 2024-06-25 |
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Hepatorenal Syndrome (16) · Fibrosis (14) · Shock, Septic (13) · Acute Kidney Injury (11) · Liver Cirrhosis (11) · Esophageal and Gastric Varices (6) · Hemorrhage (6) · Hypertension, Portal (6) · Ascites (5) · Acute-On-Chronic Liver Failure (4) · Myoma (4) · Renal Insufficiency (4) · Gastrointestinal Hemorrhage (3) · Shock (3) · Blood Loss, Surgical (2)
Institute of Liver and Biliary Sciences, India (11) · Post Graduate Institute of Medical Education and Research, Chandigarh (4) · Shanghai Zhongshan Hospital (4) · Wael Elbanna Clinic (4) · Assiut University (3) · First Affiliated Hospital, Sun Yat-Sen University (3) · General Hospital of Shenyang Military Region (3) · Hospital Clinic of Barcelona (3) · Mallinckrodt (3) · Aga Khan University (2) · Assistance Publique - Hôpitaux de Paris (2) · Ferring Pharmaceuticals (2) · National Science and Technology Council, Taiwan (2) · Ain Shams University (1) · Amany Mousa Salama Muhammed (1)
India (16) · China (14) · Egypt (11) · Spain (7) · United States (7) · France (3) · Italy (3) · Pakistan (3) · Canada (2) · Germany (2) · Switzerland (2) · Taiwan (2) · Thailand (2) · Denmark (1) · Israel (1)
Saeed S Hamid, FRCP, FACG (2) · Shiyao Chen, Professor (2) · Xingshun Qi, MD (2) · Aleksander Krag Krag, MD (1) · Andrea Morelli, MD (1) · Arun J. Sanyal, M.D. (1) · Benjamin Planquette, MD, PhD (1) · Chen Juan, M.D. (1) · Cristina Ripoll, MD (1) · Cristina Ripoll, Prof. Dr. (1) · Deba P Dhibar, MD (1)
PMID 36633470, PMID 37143199, PMID 37302573, PMID 40704461, PMID 17560680, PMID 28370090, PMID 32860184, PMID 1350562, PMID 15743361, PMID 15743362, PMID 18471513, PMID 19664253, PMID 20129334, PMID 23278466, PMID 23601499, PMID 26896734, PMID 26903338, PMID 27464593, PMID 27633962, PMID 28101605, PMID 28245243, PMID 28564127, PMID 29679676, PMID 29971593, PMID 30079635, PMID 30508958, PMID 30704260, PMID 31200638, PMID 31680011, PMID 31807567, PMID 32113581, PMID 33461754, PMID 33657294, PMID 34268406, PMID 34335897, PMID 36542261, PMID 37020315, PMID 37145232, PMID 38161497, PMID 38235907, PMID 40164039, PMID 40658810, PMID 41200852, PMID 41265546, PMID 42813964
2004 (1), 2005 (1), 2017 (1), 2019 (1)