14 completed, 6 unknown, 3 active not recruiting, 3 withdrawn. 31 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 31 | Completed 14, Unknown 6, Active not recruiting 3, Withdrawn 3, Not yet recruiting 2, Terminated 2, Recruiting 1 |
Follow Hypoxic-Ischemic Encephalopathy: new trials by email Literature Review of Hypoxic-Ischemic Encephalopathy trials Research Report on Hypoxic-Ischemic Encephalopathy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluating a Wireless NIRS Device in the Neonatal Intensive Care Unit Wireless NIRS - Hypoxic-Ischemic Encephalopathy, Congenital Heart Disease | Not applicable | Recruiting | McGill University Health Centre/Research Institute of the McGill University Health Centre | 20 | 2025-11-15 | 2026-07-28 |
| Nephroprotection Following Perinatal Asphyxia: Randomized Controlled Trial Pentoxifylline, placebo distilled water - Hypoxic-Ischemic Encephalopathy, Neonatal Encephalopathy | Not applicable | Not yet recruiting | Alexandria University | 30 | 2025-07-30 | 2025-07-28 |
| The Effect of Maternal Scent and Knitted Octopus Application on Pain in Infants Diagnosed With Neonatal Asphyxia and Receiving Therapeutic Hypothermia Treatment scent - Hypoxic-Ischemic Encephalopathy, Pain | Not applicable | Completed | Alev Sivasli | 45 | 2024-12-30 | 2026-04-13 |
| Comparative Outcomes Related to Delivery-room Cord Milking In Low-resourced Kountries Umbilical cord milking - Hypoxic-Ischemic Encephalopathy, Birth Asphyxia | Not applicable | Active not recruiting | Nemours Children's Clinic | 3442 | 2022-10-17 | 2026-09-01 |
| Umbilical Cord Milking in Neonates Who Are Depressed at Birth-Developmental Follow Up (MIDAB-FU) Umbilical Cord Milking - Hypoxic-Ischemic Encephalopathy, Birth Asphyxia | Not applicable | Withdrawn | Nemours Children's Clinic | 2022-10-17 | 2023-04-25 | |
| Comparative Outcomes Related to Delivery-room Cord Milking In Low-resourced Kountries Developmental Follow Up Umbilical Cord Milking - Hypoxic-Ischemic Encephalopathy, Birth Asphyxia | Not applicable | Active not recruiting | Nemours Children's Clinic | 3442 | 2022-10-17 | 2026-07-13 |
| Effects of a Physical Therapy Intervention on Motor Delay in Infants Admitted to a Neonatal Intensive Care Unit Physical Therapy intervention - Motor Delay, Premature Birth | Not applicable | Active not recruiting | Shirley Ryan AbilityLab | 222 | 2022-10-01 | 2026-07-31 |
| Spinal Stimulation and Mobility Devices Mobility Device, Spinal Stimulation - Cerebral Palsy, Stroke | Not applicable | Completed | University of Washington | 10 | 2022-08-04 | 2026-09-18 |
| Efficacy Evaluation of UCB-MNCs in the Treatment of Refractory Neonatal Diseases Mononuclear cells, Mild hypothermia therapy, Breathing support technique - Hypoxic-Ischemic Encephalopathy, Bronchopulmonary Dysplasia | Not applicable | Unknown | Shandong Qilu Stem Cells Engineering Co., Ltd. | 120 | 2022-04-01 | 2024-05-24 |
| Therapeutic Intervention Supporting Development From NICU to 6 Months for Infants Post Hypoxic-Ischemic Encephalopathy Sensorimotor Intervention - Cerebral Palsy, Hypoxic-Ischemic Encephalopathy | Not applicable | Completed | University of Southern California | 11 | 2022-02-18 | 2026-06-26 |
| Umbilical Cord Milking Versus Immediate Cord Clamping in Full Term Neonates (≥ 37 Weeks) Requiring Resuscitation Umbilical cord milking, Immediate cord clamping - Hypoxic-Ischemic Encephalopathy, Perinatal Asphyxia | Not applicable | Completed | Lady Hardinge Medical College | 200 | 2022-02-05 | 2024-07-09 |
| RIC in HIE: A Safety and Feasibility Trial Remote Ischemic Conditioning - Hypoxic-Ischemic Encephalopathy | Not applicable | Completed | The Hospital for Sick Children | 32 | 2022-01-17 | 2024-03-07 |
| Effect of Non-nutritive Sucking on Transition to Oral Feeding in Infants With Asphyxia Non-Nutritive Sucking - Swallowing Disorder, Perinatal Asphyxia | Not applicable | Completed | Medipol University | 100 | 2021-11-01 | 2023-10-06 |
| Babies in Glasses; a Feasibility Study. Near vision spectacles - Cerebral Visual Impairment, Refractive and Accommodative Disorders | Not applicable | Unknown | Great Ormond Street Hospital for Children NHS Foundation Trust | 55 | 2021-09-09 | 2022-09-29 |
| Early Virtual Intervention for Infants With CP Following HIE Diagnosis Virtual Care - Cerebral Palsy, Hypoxic-Ischemic Encephalopathy | Not applicable | Not yet recruiting | The Hospital for Sick Children | 150 | 2021-06-01 | 2021-06-04 |
| Maternal Hyperoxygenation for Intrapartum Fetal Heart Rate Tracing Abnormalities Room air - Perinatal Death, Respiratory Distress Syndrome, Newborn | Not applicable | Withdrawn | Loma Linda University | 2021-06-01 | 2021-08-17 | |
| Evaluation of Long-term Neurodevelopment in Neonatal Encephalopathy by Infant Treadmill Baby treadmill, Physical rehabilitation training - Hypoxic-Ischemic Encephalopathy, Periventricular Leukomalacia | Not applicable | Withdrawn | Children's Hospital of Fudan University | 2020-12-01 | 2023-12-29 | |
| Evaluation of Long-Term Gait Development in Infants With Neonatal Encephalopathy Using Infant Treadmill Baby treadmill, Conventional physical rehabilitation training - Hypoxic-Ischemic Encephalopathy, Periventricular Leukomalacia | Not applicable | Terminated | Children's Hospital of Fudan University | 20 | 2020-12-01 | 2023-12-29 |
| The Effects of Minimal Enteral Nutrition on Mesenteric Blood Flow and Oxygenation in Neonates With HIE Minimal enteral nutrition, Distilled water - Hypoxic-Ischemic Encephalopathy | Not applicable | Completed | Istanbul Training and Research Hospital | 60 | 2020-09-01 | 2024-04-03 |
| Metabolic Monitoring During Therapeutic Hypothermia (Cooling) for Hypoxic Ischaemic Encephalopathy CGM - Hypoxic-Ischemic Encephalopathy | Not applicable | Completed | Kathryn Beardsall | 16 | 2019-05-10 | 2025-04-17 |
Showing 20 of 31. Sign in to see all of them.
Hypoxia-Ischemia, Brain (31) · Hypothermia (4) · Asphyxia Neonatorum (3) · Cerebral Palsy (3) · Hypoxia, Brain (3) · Leukomalacia, Periventricular (3) · Premature Birth (3) · Brain Injuries (2) · Bronchopulmonary Dysplasia (2) · Cerebral Infarction (2) · Fetofetal Transfusion (2) · Hypoglycemia (2) · Kernicterus (2) · Blindness, Cortical (1) · Communication Disorders (1)
Brain Diseases (31) · Brain Ischemia (31) · Cardiovascular Diseases (31) · Central Nervous System Diseases (31) · Cerebrovascular Disorders (31) · Hypoxia (31) · Nervous System Diseases (31) · Pathological Conditions, Signs and Symptoms (31) · Signs and Symptoms (31) · Signs and Symptoms, Respiratory (31) · Vascular Diseases (31) · Hypoxia, Brain (28) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (10) · Infant, Newborn, Diseases (9) · Infant, Premature, Diseases (6)
Umbilical Cord Clamping (5) · Hyperbaric Oxygenation (1) · Intercellular Signaling Peptides and Proteins (1) · Melatonin (1) · Odorants (1) · Palliative Care (1) · Parenteral Nutrition, Total (1) · Pentoxifylline (1) · Spinal Cord Stimulation (1) · Telemedicine (1)
NICHD Neonatal Research Network (3) · Nemours Children's Clinic (3) · Children's Hospital of Fudan University (2) · The Hospital for Sick Children (2) · Alev Sivasli (1) · Alexa Craig (1) · Alexandria University (1) · Children's Hospital Medical Center, Cincinnati (1) · Children's Hospital of Chongqing Medical University (1) · Great Ormond Street Hospital for Children NHS Foundation Trust (1) · Istanbul Training and Research Hospital (1) · Jubilee Mission Medical College and Research Institute (1) · Kathryn Beardsall (1) · Lady Hardinge Medical College (1) · Loma Linda University (1)
United States (10) · China (6) · India (5) · Canada (3) · Turkey (Türkiye) (3) · United Kingdom (2) · Holy See (1) · Italy (1)
Abhik Das, PhD (3) · Seetha Shankaran, MD (3) · Abbot R Laptook, MD (2) · Anup Katheria, MD (2) · Barbara J. Stoll, MD (2) · Barbara Schmidt, MD, MSc (2) · Brenda B. Poindexter, MD MS (2) · Carl D'Angio, MD (2) · Edward F. Bell, MD (2) · Kathleen A. Kennedy, MD MPH (2) · Krisa P. Van Meurs, MD (2) · Kristi L. Watterberg, MD (2) · Kurt Schibler, MD (2) · Myra Wyckoff, MD (2) · Ronald N. Goldberg, MD (2)
PMID 35835616, PMID 41250198, PMID 11703564, PMID 20207600, PMID 20695757, PMID 22348528, PMID 23629670, PMID 24012586, PMID 24136687, PMID 24524452, PMID 25123212, PMID 25393080, PMID 25536254, PMID 25616519, PMID 25644966, PMID 25782975, PMID 25827279, PMID 26063194, PMID 26828941, PMID 27450203, PMID 27524449, PMID 28065781, PMID 28389438, PMID 28672318, PMID 29031859, PMID 29067428, PMID 29408249, PMID 29681183, PMID 30108392, PMID 30721531, PMID 32813884, PMID 33189747, PMID 33986149, PMID 34882200, PMID 35296895, PMID 36130761, PMID 37725613, PMID 39216619, PMID 39960680, PMID 39992674, PMID 41177395, PMID 41698720
U10HD021364 (3), U10HD021373 (3), U10HD021385 (3), U10HD027851 (3), U10HD027853 (3), U10HD027856 (3), U10HD027880 (3), U10HD027904 (3), U10HD034216 (3), U10HD036790 (3), U10HD040492 (3), U10HD040689 (3), U10HD053109 (3), U10HD068244 (3), U10HD068263 (3)