62 completed, 16 unknown, 12 recruiting, 6 withdrawn. 55 Not applicable, 11 Phase 3, 7 Phase 1, 7 Phase 2, 1 Early Phase 1.
Follow Asphyxia Neonatorum: new trials by email Literature Review of Asphyxia Neonatorum trials Research Report on Asphyxia Neonatorum
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cell-Based Therapy for White Matter Repair in Periventricular Leukomalacia Investigational Combination Product - Periventricular Leukomalacia, White Matter Disease | Early Phase 1 | Withdrawn | MGAM LLC | 2027-01-01 | 2025-07-22 | |
| Evaluation of Neonatal Acute Hypoxia at Delivery Using Fetal Physiology and Eucapnic pH Assessment Neonatal Acidemia and Hypoxia | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 1000 | 2026-10-01 | 2026-09-02 | |
| Success of Laryngeal Mask Airway (LMA) Insertion During Continuous Chest Compressions in Neonatal Resuscitation: A Randomized Crossover Simulation Study Size 1 ProSeal™ LMA - Neonatal Resuscitation, Airway Management | Not applicable | Completed | Kahramanmaras Sutcu Imam University | 32 | 2026-06-23 | 2026-07-02 |
| Effectiveness of Simulation-based Training Delivered to Special Newborn Care Providers on Resuscitation Management and Kangaroo Mother Care: Simulation-based Training for Asyphxia in Babies Trial (STAR-Baby Trial) Simulation-based training using Neonatalie - Newborn Asphyxia, Hypothermia Neonatal | Not applicable | Not yet recruiting | Integrated Development Foundation Nepal | 240 | 2026-06-01 | 2026-05-08 |
| Sustained Cord Circulation at Emergency Cesarean Section Sustained cord (≥ 180 seconds) resuscitation, Routine (< 60 seconds) cord clamping - Asphyxia Neonatorum, Fetal Hypoxia | Not applicable | Recruiting | Region Skane | 2200 | 2025-09-08 | 2026-10-29 |
| Face Mask vs Laryngeal Mask in Neonatal Resuscitation Training on Neonatal Resuscitation - Neonatal Complication, Neonatal Asphyxia | Not applicable | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 150 | 2025-05-01 | 2025-04-30 |
| Intrapartum Sildenafil in Laboring Mothers Sildenafil 50 mg Oral Tablet, Placebo Oral Tablet - Neonatal Asphyxia, Intrapartum Fetal Distress | Phase 3 | Withdrawn | University of Alabama at Birmingham | 2025-05-01 | 2025-09-16 | |
| Oral Sildenafil Citrate to Improve Maternal and Neonatal Outcomes in Low-resource Settings Sildenafil 50 mg Oral Tablet, Placebo Oral Tablet - Intrapartum Fetal Distress, Neonatal Asphyxia | Phase 3 | Withdrawn | University of Alabama at Birmingham | 2025-05-01 | 2025-09-16 | |
| Impact of Maternal Body Mass Index on Infant Hypoxic Events at Time of Delivery ,Cross-sectional Study. compare infant hypoxic events in both groups - Maternal Obesity, Hypoxia Neonatal | Not yet recruiting | Ain Shams University | 544 | 2025-04-20 | 2025-04-09 | |
| Advanced Wireless Sensors for Neonatal Care in the Delivery Room Wireless skin sensors vital sign monitoring system, Wired vital sign monitoring system - Sudden Unexplained Infant Death, Apnea of Newborn | Not applicable | Recruiting | Guilherme Sant'Anna, MD | 600 | 2025-04-08 | 2026-05-08 |
| Hypoxia Profiles Identified in Term Newborns With Cord pH <7.00 Neonatal Acidemia and Hypoxia | Recruiting | University Hospital, Strasbourg, France | 400 | 2025-04-04 | 2026-01-12 | |
| Comparison of Visual Instructions for Inserting a Laryngeal Mask in a Neonatal Mannequin. Instructions A, Instructions B - Cardiopulmonary Resuscitation, Newborn Asphyxia | Not applicable | Completed | National University of San Marcos, Peru | 62 | 2024-10-02 | 2025-01-10 |
| Treatment of Neonatal Encephalopathy With Oral Sildenafil Suspension to Repair Brain Injury Secondary to Birth Asphyxia Sildenafil, Ora-Blend - Neonatal Encephalopathy | Phase 2 | Recruiting | Pia Wintermark | 60 | 2024-07-01 | 2026-09-17 |
| Evaluation of Maternal & Newborn Health Simulation Lab Centers of Excellence in Nepal Establishment of a simulation lab and provision of simulation based trainings - Post Partum Hemorrhage, Asphyxia; Fetal | Not applicable | Unknown | One Heart Worldwide | 1464 | 2024-05-01 | 2024-09-03 |
| Is Feeding During Therapeutic Hypothermia Safe and Can Improve Outcomes in Infants With Hypoxic-ischaemic Encephalopathy enteral feeding with mother milk or human donor breast milk - Newborn Asphyxia | Not applicable | Recruiting | Nutricia Foundation | 104 | 2024-04-15 | 2024-05-01 |
| Functional Imaging of Baby Brains Diffuse Optical Tomography - Hypoxia Ischemia, Cerebral, Hypoxia-Ischemia, Brain | Unknown | Hamilton Health Sciences Corporation | 25 | 2024-03-15 | 2024-10-23 | |
| Cooling in Mild Encephalopathy Whole body hypothermia, Targeted normothermia, Supportive neonatal intensive care - Neonatal Encephalopathy, Newborn Asphyxia | Phase 3 | Recruiting | Imperial College London | 426 | 2024-03-15 | 2026-02-06 |
| Cluster Randomized Controlled Trial Applying Helping Baby Breathe in Nepal Simulator based training to manage asphyxia and essential newborn care using neonatalie - Newborn Morbidity, Newborn Asphyxia | Not applicable | Completed | Integrated Development Foundation Nepal | 95 | 2024-02-18 | 2026-04-30 |
| Perinatal Conditions Influencing Morbidity, Mortality, and Medical Care in Newborns Infant, Premature - Preterm Birth, Low Birth Weight | Completed | HOSPITAL GINECO OBSTETRICO ISIDRO AYORA | 26000 | 2023-11-12 | 2024-10-22 | |
| Enhancing Neonatal Sucking Reflex: A Study on the Efficacy of Magnesium Sulphate in Severe Birth Asphyxia Magnesium Sulphate infusion - Birth Asphyxia | Not applicable | Completed | RESnTEC, Institute of Research | 80 | 2023-10-01 | 2024-06-24 |
Showing 20 of 106. Sign in to see all of them.
Hypoxia-Ischemia, Brain (20) · Premature Birth (8) · Asphyxia (7) · Hypothermia (7) · Neonatal Sepsis (6) · Perinatal Death (5) · Postpartum Hemorrhage (5) · Brain Diseases (4) · Fetal Distress (4) · Hypoxia (4) · Apnea (3) · Eclampsia (3) · Pre-Eclampsia (3) · Pregnancy Complications (3)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (106) · Infant, Newborn, Diseases (104) · Pathological Conditions, Signs and Symptoms (61) · Signs and Symptoms (43) · Pathologic Processes (31) · Signs and Symptoms, Respiratory (31) · Nervous System Diseases (27) · Central Nervous System Diseases (26) · Female Urogenital Diseases and Pregnancy Complications (26) · Urogenital Diseases (26) · Cardiovascular Diseases (25) · Hypoxia (24) · Brain Diseases (22) · Pregnancy Complications (22) · Vascular Diseases (22)
Umbilical Cord Clamping (9) · Sildenafil Citrate (6) · Erythropoietin (4) · Resuscitation (4) · Epoetin Alfa (3) · Masks (2) · Methods (2) · Standard of Care (2) · Tablets (2) · 2-iminobiotin (1) · Aging (1) · Air (1) · Amikacin (1) · Analgesia, Epidural (1) · Ascorbic Acid (1)
Imperial College London (5) · Sharp HealthCare (4) · Aga Khan University (3) · NICHD Global Network for Women's and Children's Health (3) · Nemours Children's Clinic (3) · University of Alberta (3) · University of California, San Francisco (3) · Centre For International Health (2) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (2) · InfanDx AG (2) · Integrated Development Foundation Nepal (2) · Life Science Inkubator (2) · Massachusetts General Hospital (2) · McGill University Health Centre/Research Institute of the McGill University Health Centre (2) · Oslo University Hospital (2)
United States (15) · Canada (11) · India (8) · Italy (8) · Uganda (7) · Turkey (Türkiye) (6) · Pakistan (5) · United Kingdom (5) · Egypt (4) · Zambia (4) · France (3) · Germany (3) · Nepal (3) · Norway (3) · Sweden (3)
Anup Katheria, MD (5) · Ola Andersson, MD PhD (3) · Ron Meyer (3) · Waldemar A Carlo, MD (3) · Georg Schmolzer, MD, PhD (2) · Sudhin Thayyil, PhD (2) · Yvonne W Wu, MD, MPH (2) · Zubair Aghai, MD (2) · Abeer Salamah, Lecturer (1) · Ahmed Maged, MD (1) · Alistair J Gunn, M.D., Ph.D. (1) · Ana Langer, MD (1) · Andrew D Weeks, MD (1) · Anil Gulati (1) · Anna Tarocco, MD (1)
PMID 24524452, PMID 41250198, PMID 11900034, PMID 14977901, PMID 15036740, PMID 15721471, PMID 15724034, PMID 15885291, PMID 15885292, PMID 16188811, PMID 16199715, PMID 16989935, PMID 17329511, PMID 18450889, PMID 18492509, PMID 18784420, PMID 19797281, PMID 19896902, PMID 20164485, PMID 20385632, PMID 20483522, PMID 20937655, PMID 21292711, PMID 21816050, PMID 22258133, PMID 22542215, PMID 22950861, PMID 23008465, PMID 23149172, PMID 23440789, PMID 23800194, PMID 24366463, PMID 25439577, PMID 25631390, PMID 26169430, PMID 26283669, PMID 26473001, PMID 26857710, PMID 26874298, PMID 27496260, PMID 27582031, PMID 27799322, PMID 28427883, PMID 28863023, PMID 28912163, PMID 29728142, PMID 29866591, PMID 29895572, PMID 30009926, PMID 30026911
R01HD102967 (2), 2015 (1), 2017 (1), R01HD096023 (1), R03HD105224 (1), R25TW009337 (1), U01HD043464 (1)