446 completed, 53 unknown, 52 terminated, 50 recruiting. 290 Not applicable, 113 Phase 2, 63 Phase 1, 57 Phase 3, 49 Phase 4.
Follow Hypoglycemia: new trials by email Literature Review of Hypoglycemia trials Research Report on Hypoglycemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Behavioural Problems and Cognition in Children With Hypoglycemia Unawareness in Type-1 Diabetes Mellitus Psychological Interventions for children and adolescents - Type 1 Diabetes | Not applicable | Not yet recruiting | University of Pittsburgh | 50 | 2026-12-01 | 2026-07-07 |
| The BRIGHT Study (Device Name: HALO System) The HALO System - Diabetes Mellitus - Type 1, Diabetes Mellitus - Type 2 | Not applicable | Not yet recruiting | Indigo Diabetes NV | 12 | 2026-12-01 | 2026-08-04 |
| Study of the Safety and Efficacy of Pancreatic Endocrine Cells in Adult Patients With Type 1 Diabetes Allogeneic pancreatic endocrine cell clusters - Diabete Mellitus, Diabete Type 1 | Phase 1 / Phase 2 | Not yet recruiting | Seraxis | 9 | 2026-11-01 | 2026-10-19 |
| Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of PAL-119 in Healthy Volunteers and Adult Participants With Type 1 or Type 2 Diabetes PAL-119, Placebo - Healthy Volunteers and Diabetes Participants | Phase 1 / Phase 2 | Not yet recruiting | Paulex Bio Inc. | 147 | 2026-11-01 | 2026-10-28 |
| Comparing Glycemic Outcomes of Carbohydrate Counting vs. Fixed Mealtime Insulin Dosing in Hospitalized Patients With Hyperglycemia Carbohydrate-counting-based prandial rapid-acting insulin dosing, Flexible fixed mealtime rapid-acting insulin dosing based on percentage of meal consumed - Diabetes Type 2 on Insulin, Hypoglycemia (Diabetic) | Not applicable | Not yet recruiting | Mayo Clinic | 500 | 2026-10-01 | 2026-09-08 |
| Enhancing Shared Decision-making to Guide Care for People With Dementia and Diabetes Continuous Glucose Monitoring - Diabetes, Alzheimer's Disease (Incl Subtypes) | Not applicable | Recruiting | Indiana University | 62 | 2026-09-29 | 2026-10-05 |
| Umbilical Cord Glucose For the screening, the interventions will be glucose measurements (and possibly G-BOBH), while follow-up assessments will include Bayley testing, EEG, and MRI. - Congenital Hyperinsulinism (CHI) | Not applicable | Not yet recruiting | Odense University Hospital | 50 | 2026-09-01 | 2026-08-31 |
| Implementation of Networked Continuous Glucose Monitoring With Telemetry Within the Intensive Care Unit (ICU-TeleCGM) Dexcom G7, ViewsEMR telemetry - Type 1 Diabetes, Type 2 Diabetes Treated With Insulin | Not yet recruiting | Imperial College Healthcare NHS Trust | 70 | 2026-08-01 | 2026-08-17 | |
| Perioperative Hypoglycemia in Diabetic Patients Undergoing Vitrectomy: a Masked CGM Prospective Observational Study Masked continuous glucose monitoring (FreeStyle Libre 2®) - Diabetes Mellitus, Hypoglycemia | Not yet recruiting | Yonsei University | 85 | 2026-07-15 | 2026-07-10 | |
| Anakinra for the Treatment of Postprandial Hypoglycemia in a Patient With Total Gastrectomy and End-Stage Renal Disease Anakinra (interleukin-1 receptor antagonist), Placebo Comparator (0.9% NaCl) - Postprandial Hypoglycemia, End-stage Renal Disease (ESRD) | Phase 2 | Not yet recruiting | Marc Donath | 1 | 2026-07-01 | 2026-05-12 |
| Closed Loop Glucose Control in a Simulated ICU Setting FUSION closed loop glucose control system - Type 1 Diabetes, Type 2 Diabetes | Not applicable | Not yet recruiting | Ideal Medical Technologies | 6 | 2026-07-01 | 2026-06-12 |
| GlycoQuest: An AI-Adaptive CGM-Integrated Serious Game for Pediatric Type 1 Diabetes GlycoQuest Digital Therapeutic, Enhanced Digital Psychoeducation - Type 1 Diabetes Mellitus (T1DM), Diabetes Distress | Not applicable | Recruiting | Shifa International Hospital | 110 | 2026-06-01 | 2026-07-24 |
| Developing a Colonoscopy Preparation Protocol for Patients With Diabetes timing of cleansing and procedure - Hypoglycaemia, Diabete Mellitus | Not applicable | Not yet recruiting | Queen's University | 40 | 2026-06-01 | 2026-04-24 |
| Miniaturized Breath-based Sensor for the Detection of Hypo- and Hyperglycemia Sensing Device and Tedlar Bags - Diabetes, Hyperglycemia | Not applicable | Recruiting | Indiana University | 40 | 2026-05-31 | 2026-07-10 |
| Hypoglycemia Fear Affect Autonomic Function, Physical Activity, and Exercise Capacity in Type I Diabetes No intervention (observational study) - Type 1 Diabetes Mellitus | Not yet recruiting | Ordu University | 67 | 2026-05-02 | 2026-04-14 | |
| FEAR of HYPOGLYCEMIA in PATIENTS WITH DIABETES Diabetes Mellitus, Diet, Healthy | Recruiting | Bilecik Seyh Edebali Universitesi | 100 | 2026-04-15 | 2026-09-16 | |
| A Study of Endocrine, Metabolic, and Genetic Risk Factors of Pediatric Persistent Hypoglycemia at Sohag University Hospital Hypoglycaemia | Not yet recruiting | Sohag University | 50 | 2026-04-15 | 2026-04-16 | |
| Validation of Remote Photoplethysmography for Non-Invasive Estimation of Blood Glucose and HbA1c Diabetes Mellitus, Hyperglycaemia (Diabetic) | Not yet recruiting | Tarumanagara University | 300 | 2026-03-23 | 2026-04-20 | |
| The Real-World Control-IQ Glycemic Control and Quality of Life Study in Type 1 Diabetes in France t:slim X2 insulin pump with Control-IQ technology (Control-IQ System) - Diabetes Mellitus, Type 1 | Recruiting | Tandem Diabetes Care, Inc. | 350 | 2026-03-03 | 2026-10-14 | |
| Effect of Ambient Temperature on Blood Glucose and Insulin Absorption in Adults With Type 1 Diabetes Environmental Temperature Exposure - Type 1 Diabetes Mellitus | Not applicable | Not yet recruiting | Institut de Recherches Cliniques de Montreal | 30 | 2026-03-01 | 2026-03-24 |
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Diabetes Mellitus, Type 1 (265) · Diabetes Mellitus (138) · Hyperglycemia (110) · Diabetes Mellitus, Type 2 (88) · Insulin Resistance (56) · Motor Activity (48) · Congenital Hyperinsulinism (37) · Hyperinsulinism (23) · Glucose Metabolism Disorders (17) · Diabetes Complications (13) · Critical Illness (12) · Insulinoma (12) · Metabolic Diseases (12) · Fasting (9)
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Insulin (35) · Glucagon (32) · Continuous Glucose Monitoring (26) · Insulin Aspart (22) · Glucagon-Like Peptide 1 (17) · Insulin Glargine (17) · dasiglucagon (16) · Sodium Chloride (14) · Exercise (13) · Glucose (13) · exendin (9-39) (12) · Insulin, Regular, Human (10) · Islets of Langerhans Transplantation (10) · fluorodopa F 18 (9) · Methods (8)
Institut de Recherches Cliniques de Montreal (27) · Steno Diabetes Center Copenhagen (17) · University of Minnesota (15) · Joslin Diabetes Center (14) · Zealand Pharma (14) · Insel Gruppe AG, University Hospital Bern (12) · Xeris Pharmaceuticals (11) · Yale University (11) · Eli Lilly and Company (10) · Jaeb Center for Health Research (10) · Florida Atlantic University (8) · Brigham and Women's Hospital (7) · University Hospital, Basel, Switzerland (7) · Indiana University (6) · National Institute of Allergy and Infectious Diseases (NIAID) (6)
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Bernhard J. Hering, M.D. (5) · Christoph Stettler, MD (5) · Christoph Stettler, Prof. MD (5) · John Lum, MS (5) · Remi Rabasa-Lhoret (5) · Stephen N. Davis, MD (5) · Betty Tuller, PhD (4) · Bruce A Buckingham, MD (4) · Eyal Dassau, PhD (4) · Mary Elizabeth Patti, MD (4) · Robert Sherwin, MD (4) · Rubina Heptulla, MD (4)
PMID 15793249, PMID 17339500, PMID 2012085, PMID 21388440, PMID 22996144, PMID 23438305, PMID 25393157, PMID 28941330, PMID 31615852, PMID 34282646, PMID 34620618, PMID 36482870, PMID 37166980, PMID 37526194, PMID 38635313, PMID 39780302, PMID 10371488, PMID 11023138, PMID 11315822, PMID 11889147, PMID 1494764, PMID 14961992, PMID 15138460, PMID 15713772, PMID 15857224, PMID 15920041, PMID 16241867, PMID 16302286, PMID 16373890, PMID 16505513, PMID 16800753, PMID 17003293, PMID 17065680, PMID 17192346, PMID 17236890, PMID 17416785, PMID 17513708, PMID 17519307, PMID 17583795, PMID 17659061, PMID 17682088, PMID 17717285, PMID 17895314, PMID 18332163, PMID 18456072, PMID 18512043, PMID 18594062, PMID 18703486, PMID 18786961, PMID 19056608
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